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chronic hepatitis patients
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  慢性肝炎患者
     The mean loads of HCV RNA in liver cirrhosis and hepatocelluar carcinoma patients were significantly higher than those in chronic hepatitis patients (7.75±0.29, 7.86±0.32 vs 4.67±0.41, P<0.05), and there was also a positive correlation between HCV RNA loads and ALT level (r= 0.89,t= 8.29, P<0.05).
     在HCV抗体阳性患者中, 肝硬化和肝癌患者的HCV RNA含量显著高于慢性肝炎患者(7.75±0.29,7.86±0.32 vs 4.67±0.41,P<0.05), 而且HCV RNA含量与ALT水平呈正相关(r=0.89, t=8.29,P<0.05).
短句来源
     The incidence of IETM is 41/80(51.25%)in chronic hepatitis patients. The levels of ALT、TBIL、IL-4、IL-10 in ET positive were significantly higher than in ET negative and the level of IL-12 and the ratio of Th1/Th2 was decreased obviously.
     在慢性肝炎患者中,内毒素血症的发生率为41/80(51.25%),内毒素阳性组(ET positive)与阴性组(ET negative)比较,ALT、TBIL、IL-4、IL-10水平均显著升高,而IL-12水平和Th1/Th2比值明显降低。
短句来源
     The results show that out of 15 HCV RNA positive chronic hepatitis patients, 8 were genotype Ⅱ/1b 7 were type 6a.
     结果显示,15例慢性肝炎患者中,8例为Ⅱ/1b基因型,7例为6a型。
短句来源
     Results of 623 liver diseases patients,9.8%(61/623)were hepatogenic diabetes,of 396 chronic hepatitis patients, 7.1%(28/396) were hepatogenic diabetes, of 78 chronic failure hepatitis patients,6.4%(5/78)were hepatogenic diabetes, of 149 liver cirrhosis patients, 22.1%(33/149) were hepatogenic diabetes (P<0.01).
     结果肝源性糖尿病的发生率在乙型肝炎患者中为9.8%(61/623),其中慢性肝炎患者中为7.1%(28/396),慢性重型肝炎中为6.4%(5/78); 肝硬化中为22.1%(33/149),与慢性肝炎、慢性重型肝炎相比,差异显着(P<0.01)。
短句来源
     The HBeAg positive rate of chronic hepatitis patients was higher than asymtomatic HBsAg carr- iers significantly(P<0.005).
     肝功能异常率随着HBsAg 滴度的升高而明显增加(P<0.005),而且慢性肝炎患者的 HBeAg 阳性率显著高于无症状 HBsAg 携带者(P<0.005)。
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  慢性肝炎
     The mean loads of HCV RNA in liver cirrhosis and hepatocelluar carcinoma patients were significantly higher than those in chronic hepatitis patients (7.75±0.29, 7.86±0.32 vs 4.67±0.41, P<0.05), and there was also a positive correlation between HCV RNA loads and ALT level (r= 0.89,t= 8.29, P<0.05).
     在HCV抗体阳性患者中, 肝硬化和肝癌患者的HCV RNA含量显著高于慢性肝炎患者(7.75±0.29,7.86±0.32 vs 4.67±0.41,P<0.05), 而且HCV RNA含量与ALT水平呈正相关(r=0.89, t=8.29,P<0.05).
短句来源
     [Results] Compared with the healthy subjects (5.9±2.0 pg/mL), the levels of IL-15 were significantly increased in chronic hepatitis patients (9.7±2.7) and severe hepatitis patients (18.3±7.3), especially in the latter (P <0.01).
     结果与正常对照组血清IL-15(5.9±2.0pg/mL)相比,慢性肝炎组(9.7±2.7)pg/mL和重型肝炎组(18.3±7.3)均差异有显著性,尤其以重型肝炎患者升高为甚(P<0.01);
短句来源
     The incidence of IETM is 41/80(51.25%)in chronic hepatitis patients. The levels of ALT、TBIL、IL-4、IL-10 in ET positive were significantly higher than in ET negative and the level of IL-12 and the ratio of Th1/Th2 was decreased obviously.
     在慢性肝炎患者中,内毒素血症的发生率为41/80(51.25%),内毒素阳性组(ET positive)与阴性组(ET negative)比较,ALT、TBIL、IL-4、IL-10水平均显著升高,而IL-12水平和Th1/Th2比值明显降低。
短句来源
     The results show that out of 15 HCV RNA positive chronic hepatitis patients, 8 were genotype Ⅱ/1b 7 were type 6a.
     结果显示,15例慢性肝炎患者中,8例为Ⅱ/1b基因型,7例为6a型。
短句来源
     Results of 623 liver diseases patients,9.8%(61/623)were hepatogenic diabetes,of 396 chronic hepatitis patients, 7.1%(28/396) were hepatogenic diabetes, of 78 chronic failure hepatitis patients,6.4%(5/78)were hepatogenic diabetes, of 149 liver cirrhosis patients, 22.1%(33/149) were hepatogenic diabetes (P<0.01).
     结果肝源性糖尿病的发生率在乙型肝炎患者中为9.8%(61/623),其中慢性肝炎患者中为7.1%(28/396),慢性重型肝炎中为6.4%(5/78); 肝硬化中为22.1%(33/149),与慢性肝炎、慢性重型肝炎相比,差异显着(P<0.01)。
短句来源
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  慢性乙肝患者
     Objective:To study the expression of CD69 which is the nonage signal in CD4+ and CD8+T lymphocytes in the peripheral blood of chronic hepatitis patients.
     目的:观测慢性乙肝患者外周血CD4+、CD8+T淋巴细胞早期激活标志CD69的表达。
短句来源
     CD69 on part of the CD4+ and CD8+ T cells could be easily detected in chronic hepatitis patients,which was evidently higher than that in the healthy people.
     同样,慢性乙肝患者在激活前后也有统计学差异(P<0.01); 慢性乙肝患者在PHA刺激前有一部分CD4+、CD8+T淋巴细胞表达CD69分子,明显高于对照组(P<0.01)。
短句来源
     Methods:190 chronic hepatitis patients from our hospital since the year 2000 were reviewed,divided into two groups,and given joint antivirus treatment of interferon and thymopetide α_1,with Treatment Group one year medication while Control Group half a year.
     方法回顾我院2000年来接受抗病毒治疗中的190例慢性乙肝患者,将其分为两组,予干扰素联合α1胸腺肽抗病毒治疗,治疗组用药一年,对照组用药半年,观察疗效。
短句来源
     Results The expression of CD14 mRNA and TLR4 mRNA in peripheral blood mononuclear cells (PBMCs) were significantly higher in chronic severe hepatitis patients(2.65±0.47 and 1.36±0.25, respectively)than those in healthy controls (0.96±0.35 and 0.64±0.12, respectively p<0.01) and in chronic hepatitis patients (1.24±0.31 and 0.81±0.16 , respectively p<0.01 ).
     结果 慢性重型乙肝组患者外周血单个核细胞CD14 mRNA和TLR4 mRNA表达水平分别为2.65±0.47 、1.36±0.25,明显高于慢性乙肝患者(1.24±0.31 、0.81±0.16, p<0.01)和对照组(0.96±0.35 、0.64±0.12, p<0.01)。
短句来源
     Methods:2 ml venose blood from chronic hepatitis patients was collected,and nourished with phytohemagglutinin(PHA)(20 μg/ml). Four hours later,the expression of CD69 was tested by flow cytometry(FCM).
     方法:静脉采集慢性乙肝患者普通肝素抗凝血2ml,在植物血凝素(PHA)20μg/ml条件下进行全血培养,4h后用双色免疫荧光标记流式细胞术检测CD4+、CD8+T淋巴细胞CD69的表达。
短句来源
  “chronic hepatitis patients”译为未确定词的双语例句
     Results:CD69 on the CD4+ and CD8+ T cells was barely found in the healthy people,but was easily observed after the stimulation of PHA(P<0.01),as well as in chronic hepatitis patients;
     结果:正常人外周血只有很少量CD4+与CD8+T淋巴细胞表达CD69分子,经PHA刺激后CD4+与CD8+T淋巴细胞CD69的表达率明显升高,较刺激前有统计学差异(P<0.01)。
短句来源
     HBV preS1 antigen is acted as complement of HBeAg and HBV DNA,and a index that judges reactiveness of chronic hepatitis patients.
     PreS1抗原可以作为HBeAg和HBV-DNA的补充,也可作为判断慢性乙型肝炎患者病情活动性的一项指标。
短句来源
     The mean LN in Child A, B, C cirrhosis was also significantly higher than that in chronic hepatitis patients and in normal controls (P<0.01);
     Child A、B、C级肝硬化组LN也明显高于慢性乙型肝炎组和对照组,P值均<0.01;
短句来源
     Within the group of chronic hepatitis patients, the expression of IL-18 increased with the inflammatory activity (P<0.05), and was positively correlated with serum ALT levels (r=0.92,P<0.01).
     慢性乙型肝炎组中IL-18的表达与血清丙 氨酸氨基转移酶(ALT)水平呈正相关(r=0.92,P<0.01)。
短句来源
     The semi-quantitative analysis showed that the scope of ADP in SH patients was significantly larger than that in acute and chronic hepatitis patients ( x2= 63.62, P < 0.05), and the scope of ADP in subacute severe hepatitis and chronic severe hepatitis patients was also significantly larger than that in acute severe hepatitis patients.
     重型肝炎ADP范围明显大于普通肝炎(x~2=63.63,P<0.05),亚急性重型肝炎和慢性重型肝炎病例ADP范围明显大于急性重型肝炎病例。
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  chronic hepatitis patients
In HBe antigen-negative cases, by contrast, significant difference in the frequency of T1653/V1753 mutants was found between blood donors (22%) and chronic hepatitis patients (67%).
      
HCV/1b-infected chronic hepatitis patients received 9 MU IFNα2a everyday but Sunday for 2 weeks and thrice a week for next 10 weeks, and 76 patients became HCV RNA-negative while 81 remained positive.
      
High-dose (9 MU) long-term (60 weeks) alfa-interferon therapy for chronic hepatitis patients infected with HCV genotype 1b
      
The genomes of nine GBV-C/HGV isolates from Japanese chronic hepatitis patients were fully sequenced and characterized.
      
Hepatitis B Virus Genomes of Chronic Hepatitis Patients Do Not Contain Specific Mutations Related to Acute Exacerbation
      
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We have studied 298 case(male 182,female 116)of HBsAg postitive carriers,including 76 cases of chronic active hepatitis,17 case of chronic persistent hepatitis and 205 cases of asymtomatic HBsAg carrie- rs,The study shows that there is a closed relationship among HBsAg t- iter,HBeAg and liver function.Abnormal rate of liver function rises with the HBsAg titer apparently(p<0.005).The HBeAg positive rate of chronic hepatitis patients was higher than asymtomatic HBsAg carr- iers significantly(P<0.005).The...

We have studied 298 case(male 182,female 116)of HBsAg postitive carriers,including 76 cases of chronic active hepatitis,17 case of chronic persistent hepatitis and 205 cases of asymtomatic HBsAg carrie- rs,The study shows that there is a closed relationship among HBsAg t- iter,HBeAg and liver function.Abnormal rate of liver function rises with the HBsAg titer apparently(p<0.005).The HBeAg positive rate of chronic hepatitis patients was higher than asymtomatic HBsAg carr- iers significantly(P<0.005).The result reminds us that the detection of HBeAg,HBsAg titer and liver function cimutaneously is very useful in the inference for incidence,infectivity,diagnosis,extent of liver lesion,as well as the prognosis of hepatitis B infection,thus,it is also helpful to take protective measurements against the hepatitis B infec- tion.

本文研究了298例乙型肝炎表面抗原(称 HBsAg)阳性者,其中76例诊断为慢性活动性肝炎,17例诊断为慢性迁延性肝炎,205例为无症状 HBsAg 携带者。研究结果表明,HBsAg 滴度与 HBeAg(乙型肝炎 e 抗原)及肝功能三者之间存在比较密切的关系,并且与慢性肝炎的发生率相关。肝功能异常率随着HBsAg 滴度的升高而明显增加(P<0.005),而且慢性肝炎患者的 HBeAg 阳性率显著高于无症状 HBsAg 携带者(P<0.005)。结果启示,检测 HBeAg和 HBsAg 滴度,肝功能试验对判断乙型肝炎感染率、传染性、早期诊断、病情转归、肝脏损害程度以及开展防治工作等方面均有现实指导意义。

20 patients received intravenous infusion of glucagon at a dose of 10μg/kg and plasma C-AMP concentration was determined before meal and 15, 30, 45, 60 min after glucagon infusion. In 8 healthy adult subjects the mean value of plasma C-AMP concentration before meal was 16±1 pmol/ml. The value in patients with chronic hepatitis was in the normal range, in patients with hepatic cirrhosis the value was higher than the normal and chronic hepatitis patients, but that of with severe hepatitis was significantly...

20 patients received intravenous infusion of glucagon at a dose of 10μg/kg and plasma C-AMP concentration was determined before meal and 15, 30, 45, 60 min after glucagon infusion. In 8 healthy adult subjects the mean value of plasma C-AMP concentration before meal was 16±1 pmol/ml. The value in patients with chronic hepatitis was in the normal range, in patients with hepatic cirrhosis the value was higher than the normal and chronic hepatitis patients, but that of with severe hepatitis was significantly lower than normal value. After glucagon infusion, plasma C-AMP concentration changed. In healthy subjects, plasma C-AMP rose at 15 min, but in cirrhotic and chronic hepatitis patients the peak of plasma C-AMP removed later and the value was higher than that of the healthy adults. In cases of severe hepatitis, liver cells seriously damaged, plasma C-AMP concentration remained at low level throughout the glucagon infusion test. The curve was quite different from that of the healthy adult and chronic hepatitis patients. Thus, whether treatment of glucagon-insulin will improve the injured liver of these patients or not is still in controversy.

观察了肝病患者20例静脉注入胰高糖素后血浆cAMP的改变。胰高糖素1mg溶于10ml生理盐水,以10μg/kg体重剂量静脉注入。并在空腹,注入胰高糖素后15、30、45、60min采血测血浆cAMP浓度。健康成人空腹为16±1pmol/ml,慢性肝炎者也在正常范围,肝硬化是26.1±1.5pmol/ml,高于健康成人组。健康成人cAMP高峰在注射胰高糖素后15min,慢性肝炎、肝硬化组高峰后移,重症肝炎反应低下,且无高峰,与健康成人及慢性肝炎组差异明显。因此对重症肝炎者施以胰高糖素-胰岛素疗法是否能改善肝实质损害,尚值得进一步商榷。

umor necrosis factor alpha(TNFα)was measured with an enzyme- linked immunosorbent assay.TNFα levels in peripheral blood of patients with twenty-one cases of chronic persistent hepatitis(7.3±9.5μg/L), fourty- two cases of chronic active hepatitis(15.4±31.1μg/L),one hundred and six cases of liver cirrhosis(11. 1±17.7 μg/L)and one hundred and ten cases of parimary hepatocellular carcino-ma(10. 9±13.3μg/L)was significantly increased when compared with normal controls(4.3±2.9μg/L)(P<0.01). There was a significant...

umor necrosis factor alpha(TNFα)was measured with an enzyme- linked immunosorbent assay.TNFα levels in peripheral blood of patients with twenty-one cases of chronic persistent hepatitis(7.3±9.5μg/L), fourty- two cases of chronic active hepatitis(15.4±31.1μg/L),one hundred and six cases of liver cirrhosis(11. 1±17.7 μg/L)and one hundred and ten cases of parimary hepatocellular carcino-ma(10. 9±13.3μg/L)was significantly increased when compared with normal controls(4.3±2.9μg/L)(P<0.01). There was a significant correlation between tumor necrosis factor a levels and ALT ele-vation and also between TNFα levels and bilirubin contents more than 100 μmol/L in chronic hepatitis patients,Tumor necrosis factor a levels was also significantly in HBV concomitant with HCV and/or HDV infection than in HBV infection alone. There was no correlation in tumor necrosis factor a levels and AFP concentrations.These findings show that tumor necrosis factor participates in the activity pro-cess of liver disease.

检测外周血肿瘤坏死因子α(TNTα)水平,显示21例慢性迂延性肝炎(CPH)、42例慢性活动性肝炎(CAH)、106例肝硬化(LC)及110例原发性肝癌(PHC)之TNFα均显著高于正常对照(P<0.01)。慢性肝炎中ALT升高及胆红素>100μmol/L者其TNFα水平显著上升。乙型肝炎病毒(HBV)合并丙型肝炎病毒(HCV)/丁型肝炎病毒(HDV)感染时TNFα水平亦显著高于单纯HBV感染。PHC患者TNFα水平与甲胎蛋白(AFP)浓度无相关性。提示TNFα参与肝脏的活动性病变过程。

 
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