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epstein-barr
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  伯斯坦-巴尔
     Paired analysis of the correlation of neurasthenia with personality, life events and Epstein-Barr virus
     神经衰弱与患者个性、生活事件及埃伯斯坦-巴尔病毒相关性的配对分析(英文)
短句来源
     OBJECTIVE: To probe the correlation of neurasthenia with personality, life events and the positive rate of serum Epstein-Barr (EB) virus.
     目的:探讨神经衰弱发病与患者个性、生活事件及血清埃伯斯坦-巴尔(EB)病毒阳性率的相关性。
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  中eb
     Methods:The Epstein-Barr virus (EBV) DNA and its gene expression products,including EBNA-1,EBNA-2, EBERs,LMP-1, ZEBRA, EA-D, VCA and MA were detected in 38 nasopharyngeal KSCCs using PCR Southernblotting hybridization, in situ hybridization and immunohistochemistry.
     方法:应用PCRSouthernblotting、原位分子杂交和免疫组化法检测38例鼻咽鳞状细胞癌组织中EB病毒DNA及其产物EBNA-1,EBNA-2,EBERs,LMP-1,ZEBRA,EA-D,VCA和MA的表达。
短句来源
     Detection of the 30 base pair deletion of Epstein-Barr virus latent membrane protein 1 in extranodal nasal type NK/T-cell lymphoma and its prognostic significance
     结外鼻型NK/T细胞淋巴瘤中EB病毒潜伏膜蛋白1基因30bp碱基缺失的检测意义及其与预后的关系
短句来源
     The Epstein-Barr Virus Encoded Latent Membrane Protein 1(EBV-LMP1) Activates Expression of CyclinD1
     鼻咽癌细胞中EB病毒编码的潜伏膜蛋白1活化cyclinD1的表达
短句来源
     Study on Epstein-Barr Virus Latent Membrane Protein 1 and Heat Shock Protein 90 β in Nasopharyngeal Carcinoma
     鼻咽癌中EB病毒潜伏膜蛋白1和热休克蛋白90β的实验研究
短句来源
     A study of Epstein-Barr virus infection in intestinal T-cell lymphoma
     肠道T细胞淋巴瘤中EB病毒感染的研究
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  “epstein-barr”译为未确定词的双语例句
     CHARACTERIZATION OF A HUMAN HERPES VIRUS-6 (HHV-6 )AND EPSTEIN-BARR VIRUS (EBV) ASSOCIATED LEUKEMIC CELL LINE, J6-1
     CHARACTERIZATION OF A HUMAN HERPES VIRUS-6(HHV-6) AND EPSTEIN-BARR VIRUS(EBV) ASSOCIATED LEUKEMIC CELL LINE,J6-1
短句来源
     Telomerase activation by Epstein-Barr virus is related to p16~(INK4A)/E2F1 regulation
     EB病毒活化端粒酶与p16~(INK4A)/E2F1调控的关系
短句来源
     The purification and application of Epstein-Barr virus gp125
     Epstein-Barr病毒壳抗原gp125的纯化和应用
短句来源
     Prokaryotic Expression of Glycoprotein gp85 of Epstein-Barr Virus
     Epstein-Barr病毒包膜糖蛋白gp85的原核表达
短句来源
     Epstein-Barr Virus and Gastric Cancer
     Epstein-Barr病毒与胃癌
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  epstein-barr
Infection frequency of Epstein-Barr virus in subgingival samples from patients with different periodontal status and its correla
      
This receptor was identified as a gene induced by the Epstein-Barr virus (EBV), and is thought to be a mediator of EBV effects on B lymphocytes.
      
Most prevalent among these agents are herpesviruses, particularly Epstein-Barr virus (EBV) and cytomegalovirus (CMV).
      
Transient global amnesia as a manifestation of Epstein-Barr virus encephalitis
      
CSF pleocytosis and serological findings indicated an acute Epstein-Barr virus encephalitis.
      
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Observations on the morphology of BJAB cells were made before and after infection with Epstein-Barr Virus (EB virus) under scanning electron microscope. The surface of uninfected BJAB cells was covered with filopodia instead of microvilli which are the major surface feature of cultivated Burkitt lymphoma cells. One day after infection, the filopodia became somewhat thick and short in a portion of cells, while in the others the filopodia even virtually disappeared and the surfaces seemed to be undulated...

Observations on the morphology of BJAB cells were made before and after infection with Epstein-Barr Virus (EB virus) under scanning electron microscope. The surface of uninfected BJAB cells was covered with filopodia instead of microvilli which are the major surface feature of cultivated Burkitt lymphoma cells. One day after infection, the filopodia became somewhat thick and short in a portion of cells, while in the others the filopodia even virtually disappeared and the surfaces seemed to be undulated with varying number of scattered "fingerlike" projections. This type of surface morphology was more predominant in the third day's infected preparations, and furthermore, clusters of blebs began to be observed. The number of bleb cells increased afterwards, at the seventh day a majority of cells had a "bleb-like excresence" appearance, very similar to the characteristic surface morphology of human myeloma cells. This typical surface architecture maintained without observable change during cell passages in vitro at least for five months. Since infection with inactivated EB virus could not induce such effects on BJAB cells as that mentioned above, it is considered the presence of EB virus genome and the expression of viral gene(s) might be involved in the changes of BJAB cell surface morphology.

在扫描电镜下观察BjAB细胞在感染EB病毒以后表面形态的变化。未受感染的BjAB细胞以表面布满丝状伪足者最多见。感染1天后,部分细胞丝状伪足缩短变粗,另部分则丝状伪足几乎全部消失,细胞表面略现皱褶和分布着疏散的“手指样”结构。感染后3天时细胞突出的变化是表面皱褶更明显,更多见;而且开始看到表面泡状结构。这种泡状结构的细胞在感染5天时数量增多,而7天后大部分细胞已呈“泡样瘤”状。观察感染后5个月的细胞,这种表面结构仍保持不变。由于用灭活的EB病毒在相同条件下感染这种细胞,表面形态未见改变,所以这种表面形态的变化应与EB病毒感染,并设想同EB病毒基因组的存在和表达有关。

A total of 532 sera from patientswith nasopharyngeal carcinoma (NPC),patients with other malignancies,patients with non-malignancies of headand neck and healthy normal controlswere tested for IgA antibody to theviral capsid antigen(VCA) of Epstein-Barr virus (EBV)by indirect immuno-fluorescence test.93. 57% of 140 untreatedNPC patients had IgA antibody to VCAwith geometric mean titer (GMT) of1: 16. 80. No antibody could be foundin sera from 114 normal controls and9 patients with other malignancies.The...

A total of 532 sera from patientswith nasopharyngeal carcinoma (NPC),patients with other malignancies,patients with non-malignancies of headand neck and healthy normal controlswere tested for IgA antibody to theviral capsid antigen(VCA) of Epstein-Barr virus (EBV)by indirect immuno-fluorescence test.93. 57% of 140 untreatedNPC patients had IgA antibody to VCAwith geometric mean titer (GMT) of1: 16. 80. No antibody could be foundin sera from 114 normal controls and9 patients with other malignancies.The positive percentage and GMT ofIgA antibody to VCA in the otherpatients were much lower than in thoseof NPC patients. Among 140 untreatedNPC patients, the positive percentageof IgA antibody to VCA showed nocorrelation with clinical stage. How-ever,the GMT of IgA antibody to VCAshowed a progressive increase withincreasing tumor stage.The GMT levelof IgA antibody to VCA declinedgradually with an increase in survivaltime among 31 treated NPC patientsafter 1 week to 12 years, whereas itincreased in 21 treated NPC patientswho had recurrence or distant metastasisafter 6 months to 14 years. The optical density(OD)mean valueof purple colorimetric response in pa-tients with stage I tumors and nonma-lignancies had no significant differencefrom those in normal subjects. However,the positive percentage and OD meanvalues of purple colorimetric responsewere greater in patients with stage Ⅲand Ⅳ tumors than in those with stage1 and Ⅱ tumors(p<0.01). The positivepercentage and OD mean values of purplecolorimetric response were greater inthose with recurrence or distantmetastasis than in survival treatedpatients. So the findings demonstratedthat measurement of serum IgA antibodyto EB virus VCA and purple colorimetricresponse are useful in serodiagnosis andmonitoring of response to treatment ofnasopharyngeal carcinoma.

本文报道采用血清EB病毒VCA—IgA抗体检测法检测放疗前后鼻咽癌病人、其他恶性肿瘤病人、非癌疾患病人以及正常人共532例。证明此法对鼻咽癌的诊断具有较高的特异性,且有早期诊断的价值。同时进行血清紫色反应检测不仅能提高鼻咽癌诊断的阳性率,还具有监测病情变化与观察疗效的作用。

An epithelial cell line, designated as CNE-2, was established from biopsy of a poorly idiff-erentiated nasopharyngeal carcinoma. A primary investigation on the diological characteristics and the relation to Epstein-Barr virus was performed. EBNA was detected in the cast-off cells from the tumor add cells of the third passage and in vitro, but disappeared after several passages. The detailed biological studies are being carried.

从一例诊断为低分化鼻咽癌病人的鼻咽部肿物活检组织建立了鼻咽癌上皮细胞株(CNE-2)。初步研究了细胞株的生物学特性和与EB病毒的关系。在病人鼻咽脱落细胞和CNE-2早代细胞中检查出EBNA,但多次传代后EBNA却转为阴性,其原因尚待进一步研究。

 
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