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intra-venous
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     The pancreatic histopathologic scores in rat group of intra-venous oxygen therapy were significantly lower than those in ANP group (P<0.05);
     胰腺的病理学评分内给氧组比ANP组明显降低 (P <0 .0 5 ) ;
短句来源
     Effects of Intra-venous Oxygen Therapy on Pancreatic Pathology and Microcirculatory Morphology in Rats with Acute Necrotizing Pancreatitis
     内给氧对ANP大鼠胰腺病理和微循环形态的影响
短句来源
     Objectives]To understand the early ultrastrucural changes of pancreatic microvessels and the alteration after intra-venous oxygen therapy in rats with acute necrotizing pancreatitis (ANP) as well as explore the relation of this therapy to pathological alteration during ANP.
     【目的】了解急性坏死性胰腺炎 (ANP)大鼠早期胰腺微血管的超微结构变化以及内给氧处理后的改变 ,并探讨内给氧与ANP病理改变的关系。
短句来源
     ANP models were established in Sprague-Dawley rats by retrograde puncture into pancreaticobiliary duct and injection of 5% sodium taurocholate. Inspection of the gross structures of intra-abdominal tissues before decapitation of the rats , evaluation of pathological scores in pancreas and scanning electron microscope were carried out in control rat group of sham-operation, ANP rat group and rat group of intra-venous oxygen therapy, respectively.
     【方法】采用逆行穿刺胰胆管并注射 5 %牛磺胆酸钠诱发大鼠ANP作为动物模型 ,分别观察假手术对照组、ANP组和内给氧组大鼠处死前腹腔内组织大体结构、并进行胰腺病理学评分和扫描电镜观察。
短句来源
     ②Compared with the findings of scanning electron microscope in ANP group, rats in group of intra-venous oxygen therapy displayed rather slighter decrease of pancreatic inter-capillary anastomosis, existence of lesser bubble-like substance and resin aggregation, and reduced number of caeca, etc.
     ②扫描电镜观察 :与ANP组比较 ,内给氧组大鼠胰腺毛细血管间吻合的减少相对减轻 ,存在泡状物和树脂聚集相对较少及盲端数量减少等现象。
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  “intra-venous”译为未确定词的双语例句
     The pretreatment regimen was intra-venous injection of cytarabin (200 mg·kg-1·d-1,-2~-1 d)and cyclophosphamide (40 mg·kg-1·d-1, -2~-1 d ).
     非清髓性预处理方案:阿糖胞苷(200 mg·kg-1·d-1, -2~-1 d)及环磷酰胺(40 mg·kg-1·d-1,-2~-l d),均为静脉滴注。
短句来源
     lumbar pain and hematuria were known as its frequent symtoms. Positive rate of acid-fast bacilli in urine sedimentation was 32.0%. Positive diagnostic rate of intra-venous excretory urogram(IVU),B ultrasound and CT was 60.7%,17.9% and 78.1% respectively.
     尿沉渣找抗酸杆菌阳性率为 32.0%,静脉尿路造影(intravenous excretory urogram, IVU)、B超、CT的诊断阳性率分别为 60.7%、17.9%、78.1%。
短句来源
     The concentrations of PIP in the blood after intra-venous infusion in single dose of 3g or 2g went up to 322. 7±28. 4 and 204. 5±16.2μg/ml. After 8hours they were 7.4±3.0 and 1. 8±0.7μg/ml.
     结果表明,静滴哌拉西林3g或2g后即刻血药浓度分别可达到322.7±28.4和204.5±16.2μg/ml,8h后仍保持7.4±3.0和1.8±0.7μg/ml;
短句来源
     While drugs in blood by intra-venous method was 1.92,2.03,1.77, 1.92,1.40 times as much as by intra-arterial method.
     血液中平均药物浓度静脉途径分别为动脉灌注方法的1、92、2.03、1.77、1.92、1.40倍。
短句来源
     Meta-analysis of comparative study in treatment of acute cerebral infarction between intra-venous thrombolysis with urokinase and other drugs
     尿激酶静脉溶栓与其它药物治疗急性脑梗死对照研究的Meta分析
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  相似匹配句对
     Intra-Abundant semigroups
     内禀富足半群(英文)
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     (5) intra-alveolar hemorrhage;
     (5)肺泡内出血;
短句来源
     The Enhanced H.264 Intra Prediction
     H.264帧内方向预测增强模式
短句来源
     Treatment of intra articular fractures
     重视关节内骨折的治疗
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     Venous Thromboembolism
     静脉血栓栓塞
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  intra-venous
The efficacy of this compound has been demonstrated in animal models in which intra-venous administration was used.
      
For the immunocompetent, pre-irradiation intra-venous or intra-arterial chemotherapy with Methotrexate alone or in combination with other agents is provided to treat tumor within multiple brain sites.
      
The 7 days course of oral and intra-venous chemotherapy consisted of CCNU and Procarbazin orally and Vincristine intra-venously (PCV), repeated after 6 weeks.
      
Two patients with recurrent medulloblastomas were treated with combined oral and intra-venous chemotherapy followed by intra-arterial BCNU.
      
The EEG activation was depressed and prevented by intra-venous injection of central cholinolyticsamizil and atropine and remained unchanged after intravenous administration of peripheral cholinolytic-antrenyl.
      
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Sb-58 is a water-soluble trivalent antimony mercaptide synthesizeed. by the reaction of Sb_2O_3 on sodium dimercaptosuccinate.The present study inves- tigated its therapeutic and toxic effects,and compared the antidotal actions of 4 dithiols against Sb-58. (1)In rabbits,which had been infected with Schistosoma japonicum,intra- venous or intramuscular injections of Sb-58 gave very good therapeutic results.AIL the rabbits were completely cured(no worm could be recovered)when the total dosage was above 350 mg/kg.In...

Sb-58 is a water-soluble trivalent antimony mercaptide synthesizeed. by the reaction of Sb_2O_3 on sodium dimercaptosuccinate.The present study inves- tigated its therapeutic and toxic effects,and compared the antidotal actions of 4 dithiols against Sb-58. (1)In rabbits,which had been infected with Schistosoma japonicum,intra- venous or intramuscular injections of Sb-58 gave very good therapeutic results.AIL the rabbits were completely cured(no worm could be recovered)when the total dosage was above 350 mg/kg.In a 3-day treatment by intramuscular route,though the total dosage(120 mg/kg)was smaller than that in the long-course,treatment, Sb-58.still exhibited a therapeutic activity no less than that of tartar emetic.In the rabbits after Sb-58 treatment,serum bromsulfalein retention was much lower than that in the control group,indicating a significant improvement of the liver function. (2)In anesthetized dogs,a single intravenous administration of 30 mg/kg produced no remarkable influence on respiration,blood pressure and electrocardio- gram.In unanesthetized dogs,intramuscular injection of 50 mg/kg did not yield any untoward reaction;toxic doses(150—200 mg/kg) elicited vomiting,reduction of food intake,hypotension,depression of S—T segment and flattening of T wave in the EKG,respiratory embarrassment,and finally death.A monkey,injected intramuscularly for3 days(total dosage 90 mg/kg),displayed neither systemic nor local irritation,without alterations in the blood pressure,liver function(BSP re- tention),glucose tolerance,and electrocardiogram. (3)The acute mortality of mice from intraperitoneal administration of Sb- 58 could be remarkably diminished by subcutaneous injections of sodium dimercap- tosuccinate or унитиол,but not by injections of BAL or BAL-glucoside.

Sb-58是二巯基丁二酸纳和Sb_2O_3:作用生成的水溶性硫醇锑(三价)化合物,本文试验其疗效和毒性,并比铰4种二巯基药物对Sb-58的解毒作用(一)感染日本血吸虫病的家兎静脉或肌肉注射Sb-58二周均有非常明显的疗效;总剂量在350毫克千克以上时,全部病兎治愈(无虫)。用于肌肉注射3天疗法时,总剂量(120毫克/千克)远较长程治疗为小,但仍获满意的疗效,其疗效不亚于吐酒石。这些病兎经Sb-58治疗后,血清BSP存留率此不治疗对照粗均有显著下降,显示肝机能有明显的改善。(二)麻醉狗一次静脉注射30毫克/千克后,对呼吸、血压和心电图无明显影响。不麻醉狗肌肉注射50毫克/千克后无任何反应。中毒剂量(一次150—200毫克/干克)则引起呕吐、食少、心电图S-T(Ⅱ_Ⅲ)压低、T波平坦、血压下降、呼吸抑制,最后死亡。一只猴子肌肉注射3天(总剂量90毫克/千克),无局部或全身不良反应,血压、肝机能(BSP存留率)、葡萄糖耐量和心电图均无显著影响。(三)小鼠皮下注射二巯基丁二酸鈉或унитиол能使腹腔注射Sb-58急性中毒的死亡率明显减低,而注射BAL或BAL-glucoside则无效。

The pharmacologic effects of I-THP,d-THP,dl-THP,and THB on the spinalcord activities were investigated.Strychnine-convulsion,spinal reflexes and reflexdischarges were taken as indices.The results were as follows:(1)Strychnine-convulsion:In mice the threshold dose of strychnine-convul-sion was found to be 1-1.2 mg/kg.Pretreatment with 40 mg/kg of 1-THP,dl-THP,d-THP or THB could facilitate the mice convulsion and even causedtheir death.When the dose of the above-mentioned drugs were increased to 80or 180 mg/kg,the...

The pharmacologic effects of I-THP,d-THP,dl-THP,and THB on the spinalcord activities were investigated.Strychnine-convulsion,spinal reflexes and reflexdischarges were taken as indices.The results were as follows:(1)Strychnine-convulsion:In mice the threshold dose of strychnine-convul-sion was found to be 1-1.2 mg/kg.Pretreatment with 40 mg/kg of 1-THP,dl-THP,d-THP or THB could facilitate the mice convulsion and even causedtheir death.When the dose of the above-mentioned drugs were increased to 80or 180 mg/kg,the convulsion was also produced by the sub-threshold dose ofstrychnine;the larger the dose,the more vigorous the strychnine-convulsion was.(2)In spinal cats,the spinal reflex elicited by stimulating the central endof tibial nerve every 15 sec.was recorded from anterior tibial muscle.Intra-venous injections of dl-THP at 30-40 mg/kg often yielded a biphasic effect,i.e.abrief excitation followed by moderate inhibition.A single dose of 1-THP,15-40mg/kg,exhibited a prolonged inhibitory action,whilst d-THP produced onlya brief excitation.Moreover,the optical isomers of THP had no effect on neuro-muscular junctions.(3)The reflex discharges elicited by stimulating the dorsal root in the samesegment(L-7 or S-1)were recorded from the ventral root of spinal cats.Intra-venous injections of d-THP at 40 mg/kg caused a brief excitation of monosynap-tic discharge,but 1-THP inhibited both mono-and poly-synaptic discharges,dl-THP yielded a brief excitation followed by an inhibition.Under the same experimental conditions,THB exerted little effect on spinalcord activities.It is to be noted that the central inhibition produced by I-THP is weakerat the spinal than at the supraspinal level.

1.给小白鼠预先腹腔注射乙素旋光异构体、四氢小蘖碱各40毫克/公斤,均能协同阈剂量1.0—1.2毫克/公斤士的宁的惊厥。将士的宁降为阈下剂量(0.8毫克/公斤),上述药物增大剂量到80或180毫克/公斤,剂量越大,协同士的宁惊厥作用则越明显。因此,设想它们的中枢抑制作用与协同士的宁惊厥的关系是较复杂。2.用脊猫试验时,刺激腓神经,记录胫前肌的反射活动,分别静脉注射消旋乙素30—40毫克/公斤、左旋乙素15—40毫克/公斤后,反射活动受到抑制,等剂量的右旋乙素或四氢小蘖碱无明显的抑制作用。消旋乙素常常有短时的兴奋现象,右旋乙素也有之。3.在脊猫的腹根记录反射放电时,静脉注射药物40毫克/公斤,观察到左旋乙素均抑制单、多突触放电活动;而右旋体仅有短时兴奋,增强单突触反射放电。消旋乙素先有短时兴奋,随之有抑制现象。四氢小蘗碱的作用不明显。本文资料说明,消旋乙素对脊髓活动的作用,包括了右旋体的短时兴奋和左旋体的中枢抑制作用。但应该指出,左旋乙素对脊髓水平的抑制作用,不及对脊髓以上脑部位为强。

This study was undertaken to examine the acid secretion in response to intra-venous injection of morphine or Leu-enkephalin under basal conditions.Acuteexperiments were performed,the technic of Ghosh and Schild was essentiallyused.The stomach of the rat anesthetized with urethane was perfused with salineat 37℃ at a uniform rate.The perfusate collected every 10 minutes from thepyloric end of the stomach was titrated for acidity.It was found that both morphine and Leu-enkephalin caused increase in basalacid...

This study was undertaken to examine the acid secretion in response to intra-venous injection of morphine or Leu-enkephalin under basal conditions.Acuteexperiments were performed,the technic of Ghosh and Schild was essentiallyused.The stomach of the rat anesthetized with urethane was perfused with salineat 37℃ at a uniform rate.The perfusate collected every 10 minutes from thepyloric end of the stomach was titrated for acidity.It was found that both morphine and Leu-enkephalin caused increase in basalacid secretion.The maximal acid response after morphine and Leu-enkephalininjection was observed at 30 and 20 minutes respectively.The acid stimula-tory effect of morphine was completely blocked by naloxone at a dose of 1.5-2.6mg/kg.However,a significant rise in morphine-induced acid secretion was ob-served when an increased dose(3-5 mg kg)of naloxone was used.

用大鼠作急性实验,腹腔注射乌拉坦麻醉。以恒定速度将37℃的生理盐水自食道插管灌流入胃,收集从幽门插管流出的灌流液,用0.01当量的 NaOH 滴定其酸度,并计算单位时间内的总酸排出量。结果表明:静脉注射吗啡(3mg/kg)后,胃酸分泌增加,在注射后的30分钟时总酸排出量达最高水平,90分钟恢复至基础水平。静脉注射亮啡肽(2mg/kg),胃酸分泌也增加,总酸排出量于注射后20分钟达最高水平,60分钟恢复至基础水平。纳洛酮在一定剂量范围内(1.2—2.6mg/kg)可完全阻断吗啡增加胃酸分泌的作用,如剂量过大,则反增强吗啡对胃酸分泌的作用。

 
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