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ischemia-     
相关语句
  相似匹配句对
     muscle ischemia;
     供应颞肌的血管阻断致肌肉缺血;
短句来源
     Cerebral ischemia;
     脑缺血;
短句来源
     ischemia-reperfusion group(I);
     ③肝脏缺血再灌注(ischemi areperfusion,I/R)组(I);
短句来源
     ⑵ischemia-reperfusion;
     ⑵脑缺血再灌注组 ;
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  ischemia-
Effect of oxytocin on gastric ischemia-reperfusion injury in rats
      
The effect of peripherally administered oxytocin (OT) on gastric ischemia-reperfusion injury (GI-RI) and its possible mechanism were investigated.
      
These results indicated that the oxytocin could significantly protect gastric mucosal against injury induced by ischemia-reperfusion, and the oxytocin receptor was involved.
      
Choline succinate administration significantly improved memory and learning in ischemic rats and prevented the ischemia-induced decrease in the cerebral level of N-acetylaspartate.
      
Using laser confocal scanning microscope to study ischemia-hypoxia injury in rat brain slice
      
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Myocardial infarct was produced by occluding the apical branch of the left anteriordescending coronary artery. The effect of the corolla extract of Flos Carthami, the Chinese medicinal plant "Hong-Hua", on the extent of myocardial ischemia was evaluated by means of the epicardial electrographic mapping. During the 15 rain-occlusion the mapping was performed in 5 min interval, then the coronary occlusion was released. After reperfusion for 1 hr, while the Hong-Hua extract was being infused, a second occlusion...

Myocardial infarct was produced by occluding the apical branch of the left anteriordescending coronary artery. The effect of the corolla extract of Flos Carthami, the Chinese medicinal plant "Hong-Hua", on the extent of myocardial ischemia was evaluated by means of the epicardial electrographic mapping. During the 15 rain-occlusion the mapping was performed in 5 min interval, then the coronary occlusion was released. After reperfusion for 1 hr, while the Hong-Hua extract was being infused, a second occlusion and mapping was applied again as before@Hong-Hua extract (25%) in a dose of 2 g/kg reduced the average ST segment elevation. In the central infarct zone, 15 min after the first and second occlusion were 7.5±0.6 and 3.3±0.5mV respectively (P<0.001), whereas in the border zone the correspoding values of were 3.5±0.4 and 0.9±0.2mV(P<0.001). Reduction of was more Significant in the border zone than in the central zone (P<0.001).@Hong-Hua extract administered during the second occlusion markedly reduced the number of sites showing equal or greater than 2 mV ST segment elevation (NST) in the border zone as compared with occlusion alone, but NST remained unchanged in the central zone.@After administration of Hong-Hua extract, heart rate decreased from initial value of 164±11 to 144±9 beats/min (P<0.05) and tension-time index from 129.0±6.3 to 116.8±6.3 (P<0.01).@Our data suggest that Hong-Hua may reduce the infarct size following acute coronary occlusion by salving a lot of jeopardized myocardium in the border ischemic zone, and that the reduction of myocardial oxygen consumption was involved in the beneficial action of Hong-Hua.

由结扎左前降冠状动脉尖支的方法造成犬的心肌梗塞,用心外膜电图标测术评价中药红花提取液对心肌缺血程度的影响。本研究发现,红花液显著减少心外膜电图标测点ST段平均抬高程度,这种变化尤以梗塞边缘区为甚。红花液还可明显减少梗塞边缘区ST段显著抬高的标测点数。输入红花液后,心率及张力—时间指数明显减少。说明红花可以挽救梗塞边缘区濒危缺血心肌而缩小急性冠脉闭塞后的梗塞范围,这种有益作用可能与其降低心肌耗氧量有关。

The aim of replantation is not only to obtain survival of the replantedlimb, but also to achieve a satisfactory function. Since 1972, a total of88 limb or digital replantations have been performed, with 67 survivors(76%), their age ranging from 4 to 56 years. Every case has been follow-ed up regularly, and 3/4 of them have satisfactory function. The factors which determine the functional results of the replantedlimbs are:1. Age. No patient over 50 years of age had obtained excellent functional result.2. The...

The aim of replantation is not only to obtain survival of the replantedlimb, but also to achieve a satisfactory function. Since 1972, a total of88 limb or digital replantations have been performed, with 67 survivors(76%), their age ranging from 4 to 56 years. Every case has been follow-ed up regularly, and 3/4 of them have satisfactory function. The factors which determine the functional results of the replantedlimbs are:1. Age. No patient over 50 years of age had obtained excellent functional result.2. The duration of limb ischemia. When the durtion of ischemia was less then 8 hours, there were 33 survivors out of 40 replantations, and 15 of them obtained excellent results (Grade I); whereas it exceeded 8 hours, there were 34 survivors among 48 replantations, and only 4 of them obtained excellent results.3. The temperature of amputated ischemic limb. High ambient temperature had definite deleterious effect on amputated limbs. However, the way of storage of the detached limb affected the deleterious effect to certain extent. We had a case of amputation through the upper arm being stored with good cooling for 20 hours. Replantation was performed and movement of the fingers regained 2 years afterward.4. The nature of injury. Amputation with extensive local tissue damage usually does not result in good function.5. As to the chance of obtaining good functional result after replantation, complete major amputation is definitely inferior to the incomplete major amputation. In case of amputation with severe local crush of all the four fingers, which could not be replanted in situ, a better way to deal with this condition is to transplant the relatively suitable fingers available to the positions of the index and middle fingers.6. After major replantation, functional results vary mainly with the recovering condition of the injuried nerves and the flexibility of the small joints of fingers. In palm and digital replantations, the functi- onal results were mainly affected by the severity of the damage of the local bones and joints, particularly the metacarpo-phalangeal joints, and the gliding mechanism of the tendons.7. To obtain a good functional result after replantation, appropriate opera- tive procedures and meticulous postoperative management are manda- tory.

本文报告再植存活断肢67例的随访结果,提出功能考核的分级标准,对影响功能效果的因素,进行了讨论。年轻伤员,整齐的断离伤,缺血时间在8小时以内的断肢,再植后常能获得良好功能。

The effect of acute myocardial ischemia induced by coronary occlusion onthe interoceptive reflexes were examined in 29 anesthetized open-chest dogs.The results obtained were as follows:1.The carotid-occlusion pressor reflex was significantly diminished duringthe course of myocardial ischemia.After bilateral cervical vagotomy,such apressor reflex was not affected by myocardial ishemia.2.The reflex hypertension initiated by Valsalva maneuver was conspicuouslydecreased following myocardial ischemia.3.The...

The effect of acute myocardial ischemia induced by coronary occlusion onthe interoceptive reflexes were examined in 29 anesthetized open-chest dogs.The results obtained were as follows:1.The carotid-occlusion pressor reflex was significantly diminished duringthe course of myocardial ischemia.After bilateral cervical vagotomy,such apressor reflex was not affected by myocardial ishemia.2.The reflex hypertension initiated by Valsalva maneuver was conspicuouslydecreased following myocardial ischemia.3.The renal sympathetic efferent discharge was inhibited by temporary coro-nary occlusion,thus indicating the depression of activity of vasomotor center.4.In contrast to the baroreceptive reflex,the chemoreceptive reflex causedby intracarotid nicotine injection(8 μg/kg)remained unchanged throughout theperiod of myocardial ischemia.5.During myocardial ischemia,the pressor response to intravenous noradrena-line administration(1 μg/kg)exhibited as prominently as that in pre-ischemic period.6.On the basis of afore-mentioned data,it was proposed that myocardial is-chemia might inhibit the activity of vasomotor center,probably by activation ofcardiac vagal afferents,and that such an inhibitory effect might play a significantrole in the pathogenesis of cardiogenic shock.

在29只麻醉开胸犬身上,观察了急性心肌抉血对某些内感受性反射的影响,主要结果如下:(1)在阻断左前降冠状动脉分支而致急性心肌缺血期间,颈总动脉闭塞性加压反射显著减弱;切断两侧颈部迷走神经后,这一反射减弱不再出现。(2)Valsalva 试验时所诱发的反射性血压增高(超射相),在心肌缺血期间也明显减弱。(3)在急性心肌缺血过程中,肾交感神经传出放电明显减少,由此表明血管运动中枢活动受到抑制。(4)与压力感受器反射不同,颈动脉内注射烟碱(8微克/公斤)所致的化学感受性加压反射在心肌缺血期间保持不变。(5)静脉内注射去甲肾上腺素(1微克/公斤)的加压效应,在心肌缺血前后无明显差异。根据以上结果,似可认为,心肌缺血通过激活心脏迷走神经传入纤维而抑制血管运动中枢的活动,而这种抑制效应可能在心源性休克发生机制中起重要作用。

 
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