助手标题  
全文文献 工具书 数字 学术定义 翻译助手 学术趋势 更多
查询帮助
意见反馈
   mesenchymal transition 的翻译结果: 查询用时:0.2秒
图标索引 在分类学科中查询
所有学科
更多类别查询

图标索引 历史查询
 

mesenchymal transition
相关语句
  “mesenchymal transition”译为未确定词的双语例句
     0bjective:To study the epithelial to mesenchymal transition and expression level of Twist in MCF-7/ADR multidrug resistant breast cancer cells and to determine the relationship between multidrug resistance (MDR) and metastatic behavior.
     目的:观察乳腺癌多药耐药细胞MCF-7/ADR中Twist表达及上皮-间质转化现象,探讨其与MCF-7/ADR侵袭转移能力增强的相关性。
短句来源
     Conclusions:During the development of MDR, epithelial to mesenchymal transition induced by Twist may be related to the enhanced invasion and metastatic potential of multidrug resistant breast cancer cells MCF-7/ADR.
     结论:在多药耐药乳腺癌细胞MCF-7/ADR中,其侵袭力增强可能与Twist介导的EMT发生有关。
短句来源
     Expression and significance of integrin-linked kinase in the renal tubular epithelial to mesenchymal transition induced by TGFβ_1
     ILK在TGFβ_1诱导HKCs转分化过程中的表达和意义
短句来源
     Object: To investigate the variance of expression of Paxillin (Pax) in human renal tubular epithelial cells (HKCs) during undergoing tubular epithelial to mesenchymal transition (TEMT) induceded by transforming growth factor β_1 (TGF-β_1) and the result of intervention of protein tyrosine kinase (PTK) inhibitor genistein (Gen).
     目的:研究桩蛋白(paxillin,Pax)在转化生长因子β_1(transforming growth factorβ-1,TGF-β_1)诱导人肾小管上皮细胞发生小管上皮-肌成纤维细胞转分化(tubular epithelial tomesenchymal transition,TEMT)过程中表达的变化及酪氨酸激酶(protein tyrosine kinase,PTK)特异性抑制剂金雀异黄素(genistein,Gen)的干预结果。
短句来源
     Epithelial to Mesenchymal Transition Induced by HBx Protein in Hepatocellular Carcinoma and Its Molecular Mechanism
     HBx蛋白诱导肝癌细胞上皮—间叶样表型转化及其分子机制初步探讨
短句来源
更多       
  相似匹配句对
     Epithelial-to-mesenchymal transition and diabetic nephropathy
     肾小管上皮细胞表型转化与糖尿病肾病
短句来源
     Research advancement on epithelial-mesenchymal transition in oncology
     上皮-间充质转变在肿瘤学中的研究进展
短句来源
     Connection and Transition
     联系与过渡
短句来源
     On Learning Transition
     学习迁移的分析
短句来源
查询“mesenchymal transition”译词为用户自定义的双语例句

    我想查看译文中含有:的双语例句
例句
为了更好的帮助您理解掌握查询词或其译词在地道英语中的实际用法,我们为您准备了出自英文原文的大量英语例句,供您参考。
  mesenchymal transition
Long-term exposure of human renal carcinoma cells to PD98059 induces epithelial-mesenchymal transition-like phenotype and enhanc
      
Here we describe the various types of cell movements that have been studied in detail, which represent models for epithelial-to-mesenchymal transition, transepithelial migration, inflammation, wound healing and invasion.
      
Recent findings indicate that PRLs may function in regulating cell adhesion structures to effect epithelial-mesenchymal transition.
      
One of the mechanisms underlying epithelial plasticity is the epithelial-mesenchymal transition.
      
An example of growth factor-induced motility is the epithelial-mesenchymal transition induced by hepatocyte growth factor/scatter factor (HGF/SF).
      
更多          


It is an important cell biological phenomenon that epithelial cells transit into mesenchymal cells under special physiological and pathological condition. In recent years, it has been known that epithelial-mesenchymal-transition may be mediated by several intracellular signaling pathways, such as MAPK, Rho, Src, PI 3 kinase and Smads. Renal tubular epithelial cells have been observed to transit to myo-fibroblasts in renal diseases. However, the intracellular signaling pathways are rarely known....

It is an important cell biological phenomenon that epithelial cells transit into mesenchymal cells under special physiological and pathological condition. In recent years, it has been known that epithelial-mesenchymal-transition may be mediated by several intracellular signaling pathways, such as MAPK, Rho, Src, PI 3 kinase and Smads. Renal tubular epithelial cells have been observed to transit to myo-fibroblasts in renal diseases. However, the intracellular signaling pathways are rarely known. The progress on this field is reviewed.

上皮细胞在特定生理和病理情况下向间充质细胞转分化的现象是肿瘤及慢性炎症性疾病中的重要细胞生物学现象。近年来研究发现 ,细胞内信号转导途径中的MAPK通路、Rho家族激酶、Src激酶、PI3激酶和Smad通路参与调控上皮细胞转分化过程。肾小管上皮细胞在病理条件下可转分化为肌成纤维细胞 ,其细胞内信号转导机制虽已有初步研究 ,但尚所知甚少。本文将就有关的研究进展及现状进行综述

During the development of human early embryo, formation of organ primordium and organogenesis need all kinds of cell morphological transition, including epithelial-mesenchymal transition (EMT) and mesenchymal-epithelial transition (MET). If the cell transition fails to occur at the right time and in the right lace, a developmental disorder will occur, resulting in congenital malformation in severe cases or recessive maldevelopment in mild cases,easily predisposing to canceration or organ...

During the development of human early embryo, formation of organ primordium and organogenesis need all kinds of cell morphological transition, including epithelial-mesenchymal transition (EMT) and mesenchymal-epithelial transition (MET). If the cell transition fails to occur at the right time and in the right lace, a developmental disorder will occur, resulting in congenital malformation in severe cases or recessive maldevelopment in mild cases,easily predisposing to canceration or organ functional disorders. Clarifying the mechanism of cell transition may provide theoretic guidance in prevention of deformity and tumorigenesis.

在人体早期胚胎发育中,各个器官原基的形成以及器官的发生、发展均需要广泛的细胞形态转变,或上皮细胞向间充质细胞转型(EMT),或间充质细胞向上皮细胞转型(MET)。如果在规定的时间、地点和空间没有顺利实现细胞转型,器官发育就会出现障碍,重者发生先天性畸形,轻者产生隐性发育不良,从而使器官易致癌变或功能不全。研究器官发育中细胞转型的机制,可为人们从根本上预防畸形和肿瘤提供理论指导。

Objective: To observe morphological changes of epithelial-mesenchymal transition in the early stage of mice renal interstitial fibrosis. Methods: Renal interstitial fibrosis was induced by unilateral ureteral obstruction(UUO) in mice. Histological and immunohistochemical methods were used to analyze pathological changes and α-SMA expression in renal tissue. Argentum hexamethylenamine staining and transmission electron microscopy were used to observe changes of the renal tubule basement membrane. Gelatin...

Objective: To observe morphological changes of epithelial-mesenchymal transition in the early stage of mice renal interstitial fibrosis. Methods: Renal interstitial fibrosis was induced by unilateral ureteral obstruction(UUO) in mice. Histological and immunohistochemical methods were used to analyze pathological changes and α-SMA expression in renal tissue. Argentum hexamethylenamine staining and transmission electron microscopy were used to observe changes of the renal tubule basement membrane. Gelatin zymographic analysis was used to observe the expression of MMP2 and MMP9 in renal tissue. Results:The mice suffered from renal interstitial fibrosis were identified by histological analysis and α-SMA positive cells in renal tissue. Argentum hexamethylenamine staining and transmission electron-microscopy showed that the renal tubule basement membrane disrupted locally and renal tubule epithelial cells invaded into the renal interstitium in the early stage of renal interstitial fibrosis. Gelatin zymographic analysis showed that the expression of MMP2 and MMP9 was increased transitorily in the early stage of renal interstitial fibrosis. Conclusion: Renal tubule basement membrane disruption, renal tubule epithelial cells invasion into the renal interstitium, and the expression of MMP2 and MMP9 are involved in the development of renal interstitial fibrosis.

目的:探讨小鼠肾间质纤维化早期是否存在肾小管上皮细胞间充质细胞转型的形态学变化。方法:利用单侧输尿管梗阻的方法建立小鼠肾间质纤维化模型,常规组织学分析小鼠肾脏病理变化,免疫组化检测α- SMA的表达,肾基底膜六胺银染色和透射电镜观察肾小管基底膜的变化情况,明胶酶谱分析观察肾脏中MMP2和MMP9的表达情况。结果:成功地建立了小鼠肾间质纤维化模型,并被组织学分析证实。免疫组化分析显示肾脏中出现了大量表达α-SMA的细胞,肾基底膜六胺银染色和透射电镜分析显示小鼠肾间质纤维化早期肾脏出现了肾小管基底膜局部断裂和肾小管上皮细胞迁出的改变,明胶酶谱分析显示小鼠肾脏中MMP2和MMP9于肾间质纤维化早期有一过性增高变化。结论:肾小管基底膜局部断裂,肾小管上皮细胞迁出以及MMP2和MMP9的表达变化参与了小鼠肾间质纤维化早期上皮细胞间充质细胞转型的过程。

 
<< 更多相关文摘    
图标索引 相关查询

 


 
CNKI小工具
在英文学术搜索中查有关mesenchymal transition的内容
在知识搜索中查有关mesenchymal transition的内容
在数字搜索中查有关mesenchymal transition的内容
在概念知识元中查有关mesenchymal transition的内容
在学术趋势中查有关mesenchymal transition的内容
 
 

CNKI主页设CNKI翻译助手为主页 | 收藏CNKI翻译助手 | 广告服务 | 英文学术搜索
版权图标  2008 CNKI-中国知网
京ICP证040431号 互联网出版许可证 新出网证(京)字008号
北京市公安局海淀分局 备案号:110 1081725
版权图标 2008中国知网(cnki) 中国学术期刊(光盘版)电子杂志社