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severe hypoxic ischemic encephalopathy
相关语句
  重度缺氧缺血性脑病
     ② The neuron-specific enolase and interleukin-6 in serum in the mild, moderate and severe hypoxic ischemic encephalopathy groups were all higher than those in the normal control group (P < 0.05), and those were higher in the severe hypoxic ischemic encephalopathy group than in the mild and moderate groups (P < 0.05).
     ②轻度、中度、重度缺氧缺血性脑病组神经元特异性烯醇化酶、白细胞介素6均高于正常对照组(P<0.05),重度缺氧缺血性脑病组血清神经元特异性烯醇化酶、白细胞介素6高于轻度、中度组(P<0.05)。
短句来源
     ④ During the study, 5 cases of severe hypoxic ischemic encephalopathy died in the hypoxic ischemic encephalopathy group, the value of their neuron-specific enolase ranged 32.291 to 44.432 μg/L,and the average value was (39.467±4.041) μg/L,which was 3 times of the superior limit of the normal reference value (x+2s) 13.172 μg/L;
     ④在实验过程中缺氧缺血性脑病组患儿死亡5例,均为重度缺氧缺血性脑病患儿。 其神经元特异性烯醇化酶值为(32.291~44.432)μg/L,均值(39.467±4.041)μg/L,约3倍于正常参考值(x+2s)上限13.172μg/L;
短句来源
     Methods Data of 58 patients suffered from moderate to severe hypoxic ischemic encephalopathy(HIE) were retrospectively analyzed.
     方法 对 5 8例中重度缺氧缺血性脑病患儿进行回顾性分析。
短句来源
     METHODS: Thirty-two newborns with hypoxic ischemic encephalopathy, who were treated in the Department of Neonate, the Second Affiliated Hospital of Shanxi Medical University from January to April 2002, were selected as subjects (hypoxic ischemic encephalopathy group), including 12, 11 and 9 cases of mild, moderate and severe hypoxic ischemic encephalopathy respectively.
     方法:选择2002-01/04山西医科大学第二附属医院新生儿科收治的缺氧缺血性脑病患儿32例作为观察对象(缺氧缺血性脑病组)。 其中轻度缺氧缺血性脑病12例,中度缺氧缺血性脑病11例,重度缺氧缺血性脑病9例。
短句来源
     Objective:To study reversible cerebral ischemia regions of acute severe hypoxic ischemic encephalopathy(HIE) in piglet model by MRI ADC values and HSP 70.Methods:Seven days old piglets(n=45) were divided into 2 groups at random:group A(normal control group,n=5) and group B(HIE group,n=40,produced by bilateral common carotid artery occlusion and then inspiration of 4% oxygen about 1 hour).
     目的:利用磁共振ADC值测量与HSP 70免疫组化检测技术,研究新生猪急性期重度缺氧缺血性脑病(HIE)模型脑部可逆缺血区的存在与否及其演变规律。 方法:7日龄健康新生约克猪45只随机分为正常对照组(5只)和HIE组(40只)。
短句来源
  “severe hypoxic ischemic encephalopathy”译为未确定词的双语例句
     Objective To observe the curative effect of continuous intravenous drip of valium to control convulsion in neonates with moderate or severe hypoxic ischemic encephalopathy (HIE).
     目的观察持续静滴安定控制中重度新生儿缺氧缺血脑病(HIE)惊厥的疗效。
短句来源
     Clinical observation of the treatment of 81 cases of miderate to severe hypoxic ischemic encephalopathy with hyperbaric oxygen therapy
     高压氧治疗中重度新生儿缺血缺氧性脑病81例临床观察
短句来源
     Aim To study the changes of serum neuron specific enolase (NSE) and plasma endothelins (ET) in neonates with moderate and severe hypoxic ischemic encephalopathy (HIE) before and after treatment with hyperbaric oxygen (HBO), and to discuss the protective effects of HBO on HIE in neonate.
     目的了解高压氧(HBO)治疗中、重度新生儿缺氧缺血性脑病(HIE)后血清神经元特异性烯醇化酶(NSE)、血浆内皮素(ET)的变化,探讨高压氧治疗对新生儿HIE的保护作用。
短句来源
     Experimental Study on Reversible Acute Severe Hypoxic Ischemic Encephalopathy in Piglet Model:Comparison of ADC Values with HSP 70
     新生猪缺氧缺血性脑病模型可逆缺血区的ADC值与HSP 70对照研究
短句来源
     Effect of large dose of human albumin therapy on neonatal behavioral neurological assessment score and development quotients in neonates with severe hypoxic ischemic encephalopathy
     大剂量白蛋白治疗对重症缺氧缺血性脑病新生儿神经行为评分及发育商的影响
短句来源
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  相似匹配句对
     Effect of early intervention on the severe hypoxic-ischemic encephalopathy.
     早期干预对重度新生儿缺氧缺血性脑病的影响
短句来源
     Severe Optimism
     严峻的乐观主义
短句来源
     NSE is a sensitive, credible guidelineof severe brain hypoxic damage.
     NSE 可作为一个敏感的、可靠的提示较严重脑低氧-缺氧损伤的指标。
短句来源
     The MCT treated rats had more severe changes than the hypoxic rats.
     MCT大鼠上述改变重于缺氧大鼠。
短句来源
     Observation on auxiliary treatment of the middle and severe neonatal hypoxic-ischemic encephalopathy with naloxone
     纳洛酮治疗中重度新生儿缺氧缺血性脑病60例临床观察
短句来源
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  severe hypoxic ischemic encephalopathy
This presentation can be confused clinically with severe hypoxic ischemic encephalopathy.
      


AIM: To observe the therapeutic effect of citicoline plus symptomatic treatment in treating newborn infants with moderate and severe hypoxic_ischemic encephalopathy (HIE). METHODS: The 80 patients (M 44, F 36, age within 24 h after birth) received citicoline 0.125 g, iv, drip, qd, a course of 7_10 d, plus symptomatic treatment, including oxygen inhalation, 5% sodium bicarbonate, fluid therapy, anticonvulsant, energetic mixture. The other 60 patients (M 38, F 22, age <24 h ) as control...

AIM: To observe the therapeutic effect of citicoline plus symptomatic treatment in treating newborn infants with moderate and severe hypoxic_ischemic encephalopathy (HIE). METHODS: The 80 patients (M 44, F 36, age within 24 h after birth) received citicoline 0.125 g, iv, drip, qd, a course of 7_10 d, plus symptomatic treatment, including oxygen inhalation, 5% sodium bicarbonate, fluid therapy, anticonvulsant, energetic mixture. The other 60 patients (M 38, F 22, age <24 h ) as control received symptomatic treatment only. RESULTS: The total effective rates were 95% in therapy group and 68% in the control group (P<0.01). CONCLUSION: citicoline is effective for HIE.

目的:观察胞磷胆碱加对症治疗对中、重度新生儿缺氧缺血性脑病的疗效。方法:新生儿缺氧缺血性脑病80例(男性44例,女性36例;年龄为生后24h内)给予胞磷胆碱0.125g,iv,dripqd,共用7~10d。同时应用吸氧、碳酸氢钠、补液、止惊、能量合剂等对症治疗,对照组为同样病人60例(男性38例,女性22例;年龄同治疗组)只应用上述对症治疗。结果:治疗组总有效率95%;对照组有总有效率68%,P<0.01。结论:胞磷胆碱加对症治疗对新生儿缺氧缺血性脑病的效果较单纯对症治疗为优。

Objective To find out ways of early prediction of the prognosis of perinatal hypoxic brain damage. Methods Data of 58 patients suffered from moderate to severe hypoxic ischemic encephalopathy(HIE) were retrospectively analyzed. Of these patients,25 had obvious nervous system sequelae compared with 33 controls who showed no nervous system sequelae. Factors related to sequelae included history of hypoxia,onset time and duration of nervous system symptoms,state of convulsion and...

Objective To find out ways of early prediction of the prognosis of perinatal hypoxic brain damage. Methods Data of 58 patients suffered from moderate to severe hypoxic ischemic encephalopathy(HIE) were retrospectively analyzed. Of these patients,25 had obvious nervous system sequelae compared with 33 controls who showed no nervous system sequelae. Factors related to sequelae included history of hypoxia,onset time and duration of nervous system symptoms,state of convulsion and brain function(EEG,near infrared spectroscopy),and image changes after the acute phase of the disease. Results Marked differences between the study and control groups were observed. The study group showed severe inhibited state after birth, early onset of nervous system symptoms and 48% occurrence within 6 hours after birth. Symptoms lasted for more than10 days in 40%,convulsion occurred within 24 hours in 54%,and 85% showed frequent onset. It was revealed that severe brain function disorders(EEG), including multifocal long time abnormal discharge,subclinical discharge, low voltage,burst suppression waves,and spontaneous lowered brain oxygenation(near infrared spectroscopy); and extensive parenchymal or ventricular or periventricular image changes which occurred in 88% of the cases. Conclusion The inhibited state, onset time and duration of nervous system symptoms, severity of convulsion, brain function and image changes in later phase were valuable indicators for early prediction of the prognosis.

目的 探讨围产期缺氧性脑损伤患儿神经系统后遗症的早期预测方法。方法 对 5 8例中重度缺氧缺血性脑病患儿进行回顾性分析。将 2 5例有明显神经系统后遗症的患儿和 33例无后遗症的患儿进行对照分析 ,包括围产期缺氧情况、临床神经系统症状出现、持续时间、惊厥发作、脑功能状况及急性期后特征性影像学改变作了对照比较。结果 两组患儿各项比较差异均有显著性。有后遗症组表现 :围产期缺氧所致的生后严重抑制状态 ,神经系统症状出现早 ,生后 6h内发生者为48% ,症状持续 10d以上者占 40 % ,5 4%的患儿惊厥发生在 2 4h内 ,频发病例为 85 %。脑功能严重紊乱 :脑电生理活动表现为广泛、长时间异常放电 ,有临床下发作或全导低电压 ,爆发抑制等严重抑制状态。脑氧合功能异常 ,常有自发的发作性脑氧合降低现象。 88%的患儿在急性期后影像学检查表现为广泛的脑实质性病变或脑室及脑室周围病变。结论 综合分析围产儿缺氧后临床的抑制状况、神经系统症状发生、持续时间、惊厥发作情况、脑功能状态及影像学直观的脑内晚期病变特征 ,对早期预测神经系统后遗症有重要参考价值

Objective To explore the pathogenic factors of convulsion in ne onates with mild to severe hypoxic-ischemic en-cephalopathy. Methods Altogether 70 neonates with mild to severe hypoxic-ischemic encephalopathy (HIE) were admit ted into our hospital between Jan. 1988 and Jan. 2001. Serum calcium was dynami cally monitored in all the patients, with cerebral ultrasonography performed. R esults Convulsions occurred within the first and second days after birth in the neonates...

Objective To explore the pathogenic factors of convulsion in ne onates with mild to severe hypoxic-ischemic en-cephalopathy. Methods Altogether 70 neonates with mild to severe hypoxic-ischemic encephalopathy (HIE) were admit ted into our hospital between Jan. 1988 and Jan. 2001. Serum calcium was dynami cally monitored in all the patients, with cerebral ultrasonography performed. R esults Convulsions occurred within the first and second days after birth in the neonates of con-vulsion group, whose serum calcium levels were significantly dec reased during the third to sixth days in comparison with those of non-convulsio n group (P<0.01). Cerebral ultrasonography showed that 1 to 3 d after birth, cer ebral edema occurred in all the neonates of convulsion group (n=39), with 30 of them having diffuse edema. Cerebral edema was gradually alleviated in the four th to seventh day after birth. In non-convulsion group (n=31), 14 patients suffe red diffuse cerebral edema within 2 d af-ter birth, an incidence significantly l ower than that in convulsion group. Intracranial hemorrhage took place in 23 neo nates in convulsion group (58.97%), and the incidence in non-convulsion group w as only 38.7%. Conclusions The principal causes of convulsions in neonates incl ude hypoxia and cerebral edema, along with secondary causes such as birth trauma and hypocal-cemia.

目的探讨中、重度缺氧缺血性脑病(HIE)新生儿发生惊厥的病因。方法对1998年1月~2001年1月中住院的中、重度(HIE)70例患儿的血清游离钙进行动态观察、头颅B超检测,对结果进行统计学分析。结果HIE惊厥组的76.92%是发生在生后第1~2d;惊厥组血清游离钙于生后3~6d明显降低,与非惊厥组对比差异非常显著(P<0.01)。头颅B超示生后1~3d惊厥组均有脑水肿,其中弥漫性脑水肿30例,4~7d,脑水肿逐渐减轻;非惊厥组1~3d弥漫性脑水肿有14例,较惊厥组少,但4~7天时段仍有7例。惊厥组颅内出血23例,占58.97%,非惊厥组12例,占38.7%。结论HIE惊厥的主要原因是缺氧、脑水肿引起,其次是产伤和低钙等综合因素。

 
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