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active drugs
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  活性药物
    The time of vascular active drugs application was the shortest in ICBC group, which was 2.8 days, versus CBC group, 3.0 days (p>0.05), versus CC group, 3.6 days (p<0.05).
    术后血流动力学指标IcBC组优于cBc组、cC‘组,血管活性药物应用天数分别为:IcBc组2.8天,cBc组3 .0天印殉.05),CC组3.6天(P<0 .05)。
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    Conclusions Combination of mild general and epidural anesthesia is applied better, but the supplement of the blood volume or the administration with vascular active drugs should be noticed in order to reduce the fluctuation of hemodynamics.
    结论 浅全麻复合硬膜外阻滞是一种较好的麻醉方式 ,但应重视血容量补充或使用血管活性药物 ,以减少血液动力学波动。
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    \ Conclusion\ The combined inhalation intravenous anesthesia mainly with fentanyl and appropriate application of vaso active drugs are able to keep the stability of circulation during anesthesia.
    ④结论 缓慢的麻醉诱导 ,以芬太尼为主的静脉或静吸复合全麻 ,配合应用适当的血管活性药物 ,能保持围麻醉期循环稳定
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  active drugs
In our opinion, MRTs, which target locally active drugs into the desired cell compartment and thereby enhance the drug response, represent a new generation of the pharmacological agents.
      
The action of different coronary active drugs on intraand extravascular components of local myocardial perfusion
      
Coumermycin and rifampicin were the most active drugs, since not only inhibition of multiplication but also rapid elimination ofListeria monocytogenes could be achieved in normal and immunocompromised animals.
      
In animal experiments ampicillin or amoxicillin, respectively, are still the most active drugs.
      
VEGF-targeted therapy in renal cell carcinoma: Active drugs and active choices
      
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32 cases of invasive infection in burns were dealt with general tretment. Among them, 87. 5%were delayed to be hospitalized there were 19 cases with 2 and more organs damage. 19 cases were given emergent operation within 24 hours after being hospitalized with the maximum operation to cut the scabs; 9 cases died with mortality 28. 1 %. The treatment principles includeds: (1) end organ support; (2)cell function protection; (3)nutrition support; (4) active drugs of blood vessel and large dose of anti-medium...

32 cases of invasive infection in burns were dealt with general tretment. Among them, 87. 5%were delayed to be hospitalized there were 19 cases with 2 and more organs damage. 19 cases were given emergent operation within 24 hours after being hospitalized with the maximum operation to cut the scabs; 9 cases died with mortality 28. 1 %. The treatment principles includeds: (1) end organ support; (2)cell function protection; (3)nutrition support; (4) active drugs of blood vessel and large dose of anti-medium drugs were used; (5) ultraviolet blood irradiation and oxygenation (UBIO) was given before and after the operation. The paper also gives a preliminaty theoratical discussion.

本文探讨了32例烧伤并发创面侵袭性感染患者的全身治疗.本组中87.5%是延迟入院的患者,两个器官以上功能障碍19例。入院24小时内急诊手术19例,一次手术最大面积30%,连续二次手术切痂5例。死亡9例,死亡率28.1%。治疗原则:包括终未器官支持,保护细胞功能、营养支持和血管活性药物的应用,手术前后应用β-量子血,以及大量使用抗介质药物,并对治疗机理进行了探讨。

cases with open heart surgery have been treated on micro-dose medication intravenously through micro-electric pump.The vaso-active drugs and analgesics are the main administered drugs.To calculated the drugs based on one formula:Patient's weight(kg) times 3 is the total amount of drug(mg) needed,diluted in 50mls of solution and then pumped in 1ml per hour,by this way,the patient can receive 1ug·kg -1 ·min -1 of such drug.During administration,patient's vital signs are monitored...

cases with open heart surgery have been treated on micro-dose medication intravenously through micro-electric pump.The vaso-active drugs and analgesics are the main administered drugs.To calculated the drugs based on one formula:Patient's weight(kg) times 3 is the total amount of drug(mg) needed,diluted in 50mls of solution and then pumped in 1ml per hour,by this way,the patient can receive 1ug·kg -1 ·min -1 of such drug.During administration,patient's vital signs are monitored carefully and the changes are interpreted accurately and managed in time.So this may help patient to tide over perioperative period safely.

对391 例心脏直视手术病人进行经静脉微量用药的治疗。药物主要包括血管活性药和镇静药。采用深静脉穿刺,并保留穿刺导管,按照微量用药计算公式:药量(mg) = 体重(kg)·3,将此药物稀释至50ml 液体中,经微量泵泵入,泵入速度1ml·h-1 时,即等于1μg·kg1·min1 。在用药过程中,对病人的心血管功能进行加强监护。通过对微量用药的管理,认真细致的观察,及时发现问题并加以处理,为心肺复苏期维持血液动力学稳定提供了有力的救治措施。

Objective To observe the influences of combined general and epidural anesthesia on hemodynamics.Methods Twenty one patients were randomly divided into two groups, general anesthesia (GA group, n=11) and combined general and epidural anesthesia (GA+EA group, n=10). With Swan Ganz technique, hemodynamic parameters were measured 5min following 0.6 and 1.0 MAC enflurane inhalation in GA group, and 5min following 0.6 MAC enflurane inhalation and 10min after combined epidural lidocaine in GA+EA group.Results ...

Objective To observe the influences of combined general and epidural anesthesia on hemodynamics.Methods Twenty one patients were randomly divided into two groups, general anesthesia (GA group, n=11) and combined general and epidural anesthesia (GA+EA group, n=10). With Swan Ganz technique, hemodynamic parameters were measured 5min following 0.6 and 1.0 MAC enflurane inhalation in GA group, and 5min following 0.6 MAC enflurane inhalation and 10min after combined epidural lidocaine in GA+EA group.Results Compared with the baselines, in both groups with 0.6 MAC enflurane inhalation, MAP decreased significantly (P<0.05), HR, systemic vascular resistance (SVR), stroke index (SI), cardiac index (CI) changed unsignificantly(P>0.05); in GA group with 1.0 MAC enflurane inhalation, MAP, HR, SVR, SI and CI decreased significantly (P<0.05), in GA+EA group with combined epidural anesthesia, MAP and SVR markedly reduced(P<0.01), but CI and SI remained stable (P>0.05). As compared with those following 0.6 MAC enflurane inhalation, only in GA+EA group MAP and SVR decreased, and SI rose obviously (P<0.05) after combined epidural anesthesia.Conclusions Combination of mild general and epidural anesthesia is applied better, but the supplement of the blood volume or the administration with vascular active drugs should be noticed in order to reduce the fluctuation of hemodynamics.

目的 观察浅全麻复合硬膜外阻滞对血液动力学的影响。方法 随机将 2 1例择期行腹腔镜胆囊切除手术病人分为全身麻醉组 (GA组 ,11例 )和浅全麻复合硬膜外阻滞组 (GA +EA组 ,10例 ) ,采用Swan Ganz导管技术 ,分别监测GA组吸入 0 .6MAC、1.0MAC安氟醚与GA +EA组吸入0 .6MAC安氟醚基础上硬膜外注入 2 %利多卡因 7ml前后血液动力学的变化。结果 两组吸入 0 .6MAC安氟醚 ,MAP均显著下降 (P <0 .0 5 ) ,HR、SVR、SI、CI均无显著性变化 (P >0 .0 5 )。GA组吸入1MAC安氟醚 ,与基础值相比 ,MAP、HR、SVR、SI及CI显著性下降 (P <0 .0 5 )。GA +EA组硬膜外注药使MAP、SVR明显下降 (P <0 .0 5 ) ,CI无明显变化 (P >0 .0 5 ) ,SI显著升高 (P <0 .0 5 )。结论 浅全麻复合硬膜外阻滞是一种较好的麻醉方式 ,但应重视血容量补充或使用血管活性药物 ,以减少血液动力学波动。

 
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