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pathologic characters
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  病理特征
     Methods The expression levels of HIF-1α in gliomas were detected by immunohistochemistry assay, and analyzed the relationship of the HIF-1α expression to clinical pathologic characters and prognosis of the patients.
     方法采用免疫组化方法检测胶质瘤标本中HIF—1α的表达情况,分析HIF-1α与胶质瘤临床病理特征及预后关系。
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     We detected the expression of KDR mRNA in 80 different cases of ovarian tissues with semi-quantified RT-PCR technique and analyzed the relationship between the expression and clinical pathologic characters to investigate the significance of KDR mRNA expression in origination and development of ovarian serous carcinoma ( OSC ) , thus provide evidences for preventing angiogenesis, metastasis and relapse of the tumor in molecular level.
     本研究用RT-PCR结合计算机条带密度半定量分析方法,检测80例不同卵巢组织中KDR mRNA的表达水平,及KDR mRNA的表达与卵巢浆液性癌(Ovarian Serous Carcinoma,OSC)临床病理特征的关系,探讨KDR mRNA表达在卵巢上皮性浆液性肿瘤尤其是OSC发生、发展中的意义,为今后从分子水平干预肿瘤血管增生,进而预防卵巢癌转移、复发提供依据。
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     The expression of VEGF in patients with recurrence within 1 year were higher than that in patients without recurrence (71.4% vs 31.6%, P<0.05). There was no relationship between the expression of VEGF and clinic pathologic characters.
     vEGF在1年内有复发转移组的表达阳性率显著高于1年内无复发转移组(71.4%vs 31.6%,P<0.05),VEGF的表达与其它临床病理特征无关;
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     ④ There was no relationship between the expression of survivin and caspase-3 and clinic pathologic characters.
     ④Survivin和Caspase-3的阳性表达率与HCC患者的临床病理特征无关(P>0·05);
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     Objective: To test the levels of HGF and the expression of c-Met, VEGF and uPA in HCC , To investigate the relationship between the levels of HGF, c-Met, VEGF , uPA and the clinic pathologic characters, recurrence , metastasis in patients with hepatocellular carcinoma. The correlation between c-Met and VEGF , c-Met and uPA was analyzed in the study.
     目的:检测肝癌患者术前血清HGF水平与肝癌组织中c-Met、VEGF、uPA的表达,分析术前血清HGF水平、c-Met、VEGF、uPA的表达与肝癌临床病理特征、复发转移的关系,以及c-Met和VEGF、c-Met和uPA的表达是否相关。
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     Idiopathic pulmonary fibrosis (IPF) is the representative disease of interstitial lung disease(ILD). Its pathologic characters are alveolitis and pulmonary interstitial fibrosis.
     特发性肺纤维化(Idiopathic pulmonary fibrosis, IPF)是间质性肺疾病(Interstitial lung disease, ILD)的代表性疾病,以肺泡炎、肺间质纤维化为病理特点
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     Pathologic characters,surgical treatment and prognosis of 30 cases with complete information were analysed.
     并对其中临床资料完整的30例病人的病理特点、外科治疗及预后进行回顾性分析。
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     Analysis on pathologic characters of Dolichasigmoid in children
     小儿乙状结肠冗长症病理特点分析
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     Objective To explore and investigate the pathogenesis,pathologic characters,diagnosis,differential diagnosis and treatment of hepatic focal nodular hperplasia(FNH).
     目的 探讨分析肝局灶性结节性增生 (FNH)的发病机制、病理特点、诊断鉴别诊断和治疗。
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     Objective To clarify the clinical pathologic characters and biological behavior of endometrial carcinoma to give reference to early diagnosis and rational operation treatment.
     目的 :阐明子宫内膜癌的临床病理特点 ,肿瘤的生物学行为 ,为临床早期诊断和选择合适手术提供参考。
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     Methods: The protein expression of CD44V6 and E-Cad was detected by immunohistochemical technique in 48 cases of gallbladder carcinoma,29 cases of gallbladder adenoma polypi and 25 cases of chronic calculous cholecytitis, and the relationship between their expression with the clinical and pathologic characters of gallbladder carcinoma was analyzed.
     方法:应用免疫组织化学的方法检测48例胆囊癌、29例胆囊腺瘤性息肉、25例慢性结石性胆囊炎中CD44V6、E-Cad的表达情况,并分析其表达与胆囊癌临床病理的关系。
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     The expressions of MMP-9 ,VEGF, PCNA and CD34 in 82 cases with human GCT were examined using immunohistochemical staining. The relationship between them and the clinical pathologic characters are analyzed.
     [方法]采用免疫组化法检测82例骨巨细胞瘤标本MMP鄄9、VEGF、PCNA、CD34表达,分析其与骨巨细胞瘤临床病理特性的关系。
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     Objective: To study the expression of vascular endothelial growth factor-C(VEGF-C) and c-fms-like tyrosine kinase-4(Flt-4) in nonsmall cell lung cancer (NSCLC) and the relationship with the pathologic characters.
     目的:探讨血管内皮生长因子C(VEGF C)及其受体Flt4与非小细胞肺癌(NSCLC)组织的关系。
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     Methods The ultrasonographic characteristics of different bone tumors were detected by B ultrasound, and compared with the results of pathologic characters after operation.
     方法 对骨肿瘤的声像图特点进行分析 ,并与术后病理检查的结果进行比较。
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     Rats were executed in the fourteenth week and their weights of bladder, pathologic characters, microvessel densities (MVD), apoptotic indexes (AI) were surveyed.
     于第14周进行病理观察、测量膀胱总重量,微血管密度(MVD)和凋亡指数(AI)。
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  pathologic characters
The ultrasonographic characteristics of different bone tumors were studied and compared with the results of pathologic characters after operation.
      


Pathogenicity of bacterial L-forms was carried out with animal experiments. The infection with bacterial L-forms may cause interstitial inflammations of internal organs, very similar to the infections of virus and mvcoplasma. This may be a common characteristic of micrc-otgarisms without cell valls. The typical pathologic character of infections with their original bacterial forms usually can not be seen in these infections. Tuberculosis Iesions carsed by L-forms have caseous reorosis withaut tubercle...

Pathogenicity of bacterial L-forms was carried out with animal experiments. The infection with bacterial L-forms may cause interstitial inflammations of internal organs, very similar to the infections of virus and mvcoplasma. This may be a common characteristic of micrc-otgarisms without cell valls. The typical pathologic character of infections with their original bacterial forms usually can not be seen in these infections. Tuberculosis Iesions carsed by L-forms have caseous reorosis withaut tubercle formation;typhoid lesions have S typhi L-form antigen in the tissue, but no typhoid nodules. This may be referable to the failure and mistake in diagnosis.

本文通过动物实验研究报道了细菌L型的致病特征—主要引起内脏器官的间质性炎症,与病毒、支原体等缺壁微生物感染所致的病变相似。这可能是细菌L型感染的共同特征。细菌L型感染往往缺乏其原菌的典型病变特点:如结核病灶虽有干酪样坏死,但无结核结节形成;伤寒病灶虽证明有伤寒菌L型抗原存在,但缺乏伤寒性肉芽肿。这些可能是容易造成漏诊和误诊的主要原因。

Eight hundred and seventy six specimens of endometria were subjected to bacteriologi- cal and immunohistochemical studies in this article.It was found that:1)There were infiltration of lymphocyte and plasma cell or formation of lymphoid follicles in 32.5% of the case.In some other cases there were infection,yet endometrial stroma no chro- nic inflammatory cell infiltration was seen. 2)In the cases that bacterial examination was negative,no chronic inflammation was found in the endometrial stromas.3)Bacte- riological...

Eight hundred and seventy six specimens of endometria were subjected to bacteriologi- cal and immunohistochemical studies in this article.It was found that:1)There were infiltration of lymphocyte and plasma cell or formation of lymphoid follicles in 32.5% of the case.In some other cases there were infection,yet endometrial stroma no chro- nic inflammatory cell infiltration was seen. 2)In the cases that bacterial examination was negative,no chronic inflammation was found in the endometrial stromas.3)Bacte- riological examination showed that 80.9% of the infections were due to Staphylococcus aureus L-forms.4)The positive rate of bac- terial forms and L-forms of endometrial stro- ma was higher than that of the glands in immunohistochemical staining. The authors suggest that the lymphocytic infiltration and follicular formations in en- dometrial stroma are pathologic characters specific for L-form infections.Therefore it is also a diagnostic criterion for chronic en- dometritis.

本文应用微生物培养、免疫组织化学等方法,对876例子宫内膜进行了组织病理学研究。发现:1.子宫内膜细菌 L 型感染病例中,32.5%的内膜间质有淋巴细胞浸润、淋巴滤泡形成或伴有浆细胞浸润。尚有部分病例虽有感染,但无慢性炎细胞浸润。2.细菌学检查阴性病例,内膜间质无慢性炎细胞浸润。3.病原微生物培养显示70.8%为金黄色葡萄球菌 L 型感染。4.免疫组织化学证明子宫内膜间质细菌型和 L 型的检出率高于腺体。作者提出子宫内膜间质中淋巴细胞浸润或淋巴滤泡形成系细菌 L 型感染的病变特征。故也是慢性子宫内膜炎的诊断依据。

Twenty-six cases of lung hydatidosis were positively diagnosed by ultrasonography and of them were surgically confirmed later. Lung hydatidosis could be classified into 4 types ording to their ultrasonographic and pathologic characters, that is Ⅰ. single cyst; Ⅱ. ulti-daughter cyst; Ⅲ. secondary cyst and Ⅳ. multiple cyst. The conincidence of ultrasonic gnosis with surgical confirmation was 92.8% (26/28). In this study, 3 cases missed gnosis, among which 1 didn't show for it was on the back of the right...

Twenty-six cases of lung hydatidosis were positively diagnosed by ultrasonography and of them were surgically confirmed later. Lung hydatidosis could be classified into 4 types ording to their ultrasonographic and pathologic characters, that is Ⅰ. single cyst; Ⅱ. ulti-daughter cyst; Ⅲ. secondary cyst and Ⅳ. multiple cyst. The conincidence of ultrasonic gnosis with surgical confirmation was 92.8% (26/28). In this study, 3 cases missed gnosis, among which 1 didn't show for it was on the back of the right upper lobe and was d up by the ihoractic vertebrae and scapula, another didn't show clearly as it was on the ;k of the middle lobe of the right lung and was separated by the thoractic vertebrae and /ered with pulmonary alveoli, the third didn't show clearly either, because of its location at the lower part of the left lung and possible influence of chlorine in the gastrointestinal tract though diaphragmatic surface examination was done using the spleen as a sound-penetrating window. Two cases were misdiagnosed, one was a round-shaped tuberculoma of the lung, and the other was mislocated.

本文报告26例肺包虫病的超声显象检查,全部病例经手术病理证实。肺包虫病根据其声象图特征结合病理分为四型。即Ⅰ型(单纯囊型),Ⅱ型(多子囊型),Ⅲ型(继发症型),Ⅳ型(多型型)。超声诊断符合手术病理者26/28例,占92.8%。3例漏诊,1例位于右肺上叶背侧,因受胸椎与肩胛骨影响未显示,1例病变在右肺中叶背侧纵隔面,受胸椎、肩胛骨阻挡及肺泡气体影响显示不清,另1例为左肺底,虽经右侧位以脾为透声窗向膈面探查(可能于受胃肠道氯气影响有关)仍然显示不满意。误诊2例,1例肺结核瘤呈类圆形暗区误认为肺包虫囊肿,1例胸膜腔包虫病病灶显示为椭圆形囊性肿块向肺内突出而使定位判断错误。 超声波遇到肺组织产生多次反射,使位于肺组织深层未贴近胸膜脏层的占位病变不能显示。当肺包虫囊肿的某一部分贴近肺表面即可使超声波透过而显示病变的切面图象。超声显象有助于显示肺包虫囊肿的部位,形态、边缘状况、内部结构及其物理特性,可为本病的诊断与鉴别诊断,为临床治疗决策提供可靠的资料。

 
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