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severe hepatitis patients
相关语句
  重型肝炎
     IL-15 in severe hepatitis patients correlated well with TBIL (r =0.591, P <0.01).
     重型肝炎患者血清IL-15与TBIL呈正相关(r=0.591,P<0.01)。
短句来源
     [Methods] Serum IL-2,IL-6,TGFβ1,TNF-αand LPS of 36 severe hepatitis patients were determined before and after the treatment of plasma exchange(PE),continuous veno-venous hemofiltration(CVVH)etc.
     方法36例重型肝炎患者分别在血浆置换(PE)、连续静脉血液滤过(CVVH)等人工肝支持系统不同方法的治疗前后测定患者血清IL-2、IL-6、TGFβ1、TNF-α及LPS的水平,比较它们在治疗前后的变化。
短句来源
     [Results] Compared with the healthy subjects (5.9±2.0 pg/mL), the levels of IL-15 were significantly increased in chronic hepatitis patients (9.7±2.7) and severe hepatitis patients (18.3±7.3), especially in the latter (P <0.01).
     结果与正常对照组血清IL-15(5.9±2.0pg/mL)相比,慢性肝炎组(9.7±2.7)pg/mL和重型肝炎组(18.3±7.3)均差异有显著性,尤其以重型肝炎患者升高为甚(P<0.01);
短句来源
     [Objective] To observe the effect of artificial liver system to eliminate serum interleukin-2(IL-2),interleukin-6(IL-6),transforming growth factorβ1(TGFβ1),tumor necrosis factor(TNF-α),and lipopolysaccharide(LPS)of severe hepatitis,and discuss the significance of artificial liver system to the treatment of severe hepatitis patients.
     目的观察人工肝支持系统对重型肝炎肝衰竭患者血清白介素-(2IL-2)、白介素-(6IL-6)、转化生长因子β(1TGFβ1)、肿瘤坏死因子(TNF-α)及内毒素(LPS)的清除效果,进一步探讨人工肝支持系统在重型肝炎治疗中的意义。
短句来源
     Methods Serum IL-2,IL-6,TGFβ_1,TNF-α,sFas,IFN-αlevels of severe hepatitis patients before and after treatment with non-bioartificial liver were detected and compared.
     方法测定正常组、重型肝炎保守治疗组及重型肝炎人工肝治疗组治疗前后血清IL-2、IL-6、TGFβ1、TNF-α、sFas、IFN-α的水平,并进行比较。
短句来源
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  重症肝炎患者
     Results Serum T 4 and FT 4 levels increased in patients with acute hepatitis B. Levels of FT 3, FT 4 and TSH decreased in patients with chronic hepatitis B. The concentrations of serum T 3, FT 3 and TSH decreased in patients with liver cirrhosis. Serum T 3, FT 3, FT 4 and TSH levels decreased in severe hepatitis patients.
     结果 :急性乙肝患者T4 、FT4 水平升高 ,慢性乙肝患者FT3、FT4 、TSH水平降低 ,肝硬化患者T3、FT3、TSH水平降低 ,重症肝炎患者T3、FT3、FT4 、TSH水平降低。
短句来源
     Objective To study serum interleukin 6 and 8(IL 6,IL 8) in chronic and chronic severe hepatitis patients to observe the effects of hepatocyte growth promoting factor (pHGF) therapy.
     目的 研究观察慢性肝炎、慢性重症肝炎患者血清IL 6和IL 8水平在促肝细胞生长素(pHGF)治疗前后的变化。
短句来源
     Clinical significance of detection of indexes assosciated with severe hepatitis patients
     重症肝炎患者相关指标检测的临床意义
短句来源
     For the chronic severe hepatitis patients 4 weeks of pHGF treatment could reduce serum IL 6 and IL 8 levels ( P <0.05). After 8 weeks treatment these factors were all decreased( P <0.01). Meanwhile,IL 6 decreasing was related with ALT level.
     pHGF治疗组的慢性肝炎和慢性重症肝炎患者在治疗 8周后 ,其血清IL 6和IL 8水平明显下降 (P <0 .0 5) ,ALT与IL 6呈明显正相关 ;
短句来源
     Prior to or following taking PGR mixture, 33 severe hepatitis patients' blood SOD activity was determined with a simplified method of pyrogallol autoxidation.
     用简易邻苯三酚自氧化法测定了33例重症肝炎患者服用赤栀黄合剂前后全血SOD活性。
短句来源
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  重症肝炎
     Conclusion Tα1 can decrease the level of TNF-α, sIL-2R, IL-6, endotoxin and CD + 8, while increases IL-4 level, attenuating immune injury of hepatocyte in severe hepatitis patients.
     结论 Tα1是强有力的免疫调节剂 ,能降低TNF -α ,sIL -2R ,IL -6,内毒素及CD+ 8含量 ,提高IL -4水平 ,从而减轻重症肝炎时免疫反应对肝细胞的损伤。
短句来源
     Results Serum T 4 and FT 4 levels increased in patients with acute hepatitis B. Levels of FT 3, FT 4 and TSH decreased in patients with chronic hepatitis B. The concentrations of serum T 3, FT 3 and TSH decreased in patients with liver cirrhosis. Serum T 3, FT 3, FT 4 and TSH levels decreased in severe hepatitis patients.
     结果 :急性乙肝患者T4 、FT4 水平升高 ,慢性乙肝患者FT3、FT4 、TSH水平降低 ,肝硬化患者T3、FT3、TSH水平降低 ,重症肝炎患者T3、FT3、FT4 、TSH水平降低。
短句来源
     Objective To study serum interleukin 6 and 8(IL 6,IL 8) in chronic and chronic severe hepatitis patients to observe the effects of hepatocyte growth promoting factor (pHGF) therapy.
     目的 研究观察慢性肝炎、慢性重症肝炎患者血清IL 6和IL 8水平在促肝细胞生长素(pHGF)治疗前后的变化。
短句来源
     Clinical significance of detection of indexes assosciated with severe hepatitis patients
     重症肝炎患者相关指标检测的临床意义
短句来源
     For the chronic severe hepatitis patients 4 weeks of pHGF treatment could reduce serum IL 6 and IL 8 levels ( P <0.05). After 8 weeks treatment these factors were all decreased( P <0.01). Meanwhile,IL 6 decreasing was related with ALT level.
     pHGF治疗组的慢性肝炎和慢性重症肝炎患者在治疗 8周后 ,其血清IL 6和IL 8水平明显下降 (P <0 .0 5) ,ALT与IL 6呈明显正相关 ;
短句来源
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  “severe hepatitis patients”译为未确定词的双语例句
     Methods The expression of membrane CD14、CD14 mRNA and TLR4 mRNA in the peripheral blood monocytes (PBMs) from 30 cases of chronic severe hepatitis patients、20 cases of chronic hepatitis B patients and 10 cases of healthy controls were detected by flow cytometry and reverse transcription-polymerase reaction (RT-PCR) methods. Moreover, the level of plasma endotoxin and serum sCD14 were assayed by limulus amebocyte lysate test and ELISA respectively.
     方法 采用流式细胞术和逆转录-聚合酶链反应(RT-PCR)方法检测30例慢性重型乙肝患者、20例慢性乙肝患者和10例正常人外周血单核细胞上膜型CD14(mCD14)、CD14 mRNA以及TLR4 mRNA的水平,应用动态浊度法和ELISA双抗体夹心法检测血浆内毒素及血清可溶性CD14(sCD14)的水平。
短句来源
     Results: In the 102 mild, 88 moderate and 56 severe hepatitis patients, the number of cases with positive HBsAg, HBeAg and anti-HBc was 53 (51.9%), 46(52.3%) and 33( 58.9%)respectively;
     结果 :10 2例轻度、88例中度及 5 6例重度患者中血清学标志HBsAg ,HBeAg,抗 -HBc阳性模式分别为 5 3例 (5 1.9% )、4 6例(5 2 .3% )、33例 (5 8.9% ) ;
短句来源
     Comparing all the results between the severe hepatitis patients and normal group, there was distinct difference(P<0.05 or P<0.01).
     各项指标与正常对照比较,差异均有统计学意义(P<0.05或P<0.01)。
短句来源
     Methods 150 hospitalized cases of severe hepatitis patients with nosocomial fungus infection were investigated and analyzed retrospectively.
     方法应用回顾性调查方法对150例重症肝病患者医院真菌感染临床资料及相关因素进行分析。
短句来源
     For the chronic severe hepatitis patients 4 weeks of pHGF treatment could reduce serum IL-6 and IL-8 levels( P<0.05). After 8 weeks treatment these factors were all decreased( P<0.01). Meanwhile,IL-6 decreasing was related with ALT level .
     pHGF治疗组的慢性肝炎在治疗8周后,其血清IL-6和IL-8水平明显下降(P<0.05),ALT与IL-6呈明显正相关;
短句来源
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Needle biopsy specimens from 18 subacute severe hepatitis patients (SSH) and 9 biliary hepatitis patients ( BH ) were studied under optic and eltron microscopes. The volume percentage of hepatic cell cholestasis and that of chole-coagulative necrosis were determined. The data obtained were processed statistically for correlation with serai bilirubin contents. The results showed ( 1 ) Hepatic cell cholestasis and chole-coagulative necrosis were present in both SHH and BH) correlation of bilirubin...

Needle biopsy specimens from 18 subacute severe hepatitis patients (SSH) and 9 biliary hepatitis patients ( BH ) were studied under optic and eltron microscopes. The volume percentage of hepatic cell cholestasis and that of chole-coagulative necrosis were determined. The data obtained were processed statistically for correlation with serai bilirubin contents. The results showed ( 1 ) Hepatic cell cholestasis and chole-coagulative necrosis were present in both SHH and BH) correlation of bilirubin content was only found with hepatic cell "cholestasis in BH. ( 2 ) The architecture of lobules was intact in BH, but destroyed in SSH. ( 3 ) The bile excretory system was preserved in BH.The authors believe that in addition to the extent of liver cell necrosis, the condition of bile excretory system is of prognostic significance to the illness. The ultrastructural details of chole-coagulative necrosis are decribed in this paper

对29例亚急性重症肝炎及13例次淤胆性肝炎肝穿刺标本的光、电镜检查,测算了18例亚急性重症肝炎,9例淤胆性肝炎肝细胞内淤胆的容积百分比、胆汁凝固性坏死的容积百分比与临床资料进行统计学处理,指出这两类肝炎都有肝细胞内淤胆和胆汁凝固性坏死,但淤胆性肝炎肝小叶结构完整,胆汁流出道不破坏,亚急性重症肝炎肝小叶破坏。认为除肝细胞大量坏死外,胆汁流出道破坏是影响预后的另一个重要因素。本文详细描述了胆计凝固性坏死的超微结构改变。

Activity of serum inhibitory factors (SIF) were observed in 72 oases of severe hepatitis, the positive incidence of SIF was as high as 98.18%, the average inhibitory activity was 93.77±1.07% in various viral hepatitis groups.It was found that there was some relationship between SIF changes and prognosis in severe hepatitis patients, but SIF activity was not parallel to changes of SB and AFP in patient's serum. High levels of SIF activity could still be detected in the serum from severe hepatitis...

Activity of serum inhibitory factors (SIF) were observed in 72 oases of severe hepatitis, the positive incidence of SIF was as high as 98.18%, the average inhibitory activity was 93.77±1.07% in various viral hepatitis groups.It was found that there was some relationship between SIF changes and prognosis in severe hepatitis patients, but SIF activity was not parallel to changes of SB and AFP in patient's serum. High levels of SIF activity could still be detected in the serum from severe hepatitis patients who had been treated with repeated plasma exchanges. Mixed serum from severe hepatitis patients could not only inhibit lymphocyte proliferation from normal healthy people in vitro, but also remarkbly reduced the function of suppressive T cells.

作者等观察了72例重型肝炎的SIF活性,阳性率高达98.18%,平均抑制活性在各病毒性、急、慢性肝炎组中占首位(93.77±1.07%)。SIF的变化趋势与重肝预后有一定的相关性,但与血清中SB、AFP的变化不平行。经多次换血浆治疗的重肝患者的血清中仍能测到高活性的SIF。在体外,混合的重肝血清除了能抑制正常人的淋巴细胞增殖反应外,还能明显的降低抑制性细胞的功能。

Prior to or following taking PGR mixture, 33 severe hepatitis patients' blood SOD activity was determined with a simplified method of pyrogallol autoxidation. The results show that: (a) before taking PGR, the SOD activity in patient with subacute severe hepatitis (1029.11±123.25u/g Hb) is significantly lower than that of healthy control (1590.09±30.45u/g Hb), p<0.01; (b) after taking the medicine, the SOD activity in patients with various types of severe hepatitis is...

Prior to or following taking PGR mixture, 33 severe hepatitis patients' blood SOD activity was determined with a simplified method of pyrogallol autoxidation. The results show that: (a) before taking PGR, the SOD activity in patient with subacute severe hepatitis (1029.11±123.25u/g Hb) is significantly lower than that of healthy control (1590.09±30.45u/g Hb), p<0.01; (b) after taking the medicine, the SOD activity in patients with various types of severe hepatitis is gradually increased and significant for clinically curative group, p<0.01, indicating that PGR mixture possesses the potential to raise the SOD activity and protect liver cells from damage induced by O_2~·~-.

用简易邻苯三酚自氧化法测定了33例重症肝炎患者服用赤栀黄合剂前后全血SOD活性。结果:1.用药前亚急性重症肝炎患者全血SOD活性(1029.11±128.25u/gHb)明显低于健康人(1590.09±30.45u/gHb)P<0.02;2.用药后各型重症肝炎患者全血SOD活性逐渐上升,临床治愈组上升最为显著,与服药前相比有极显著性统计学意义,P<0.01。提示赤栀黄合剂有提高SOD活性,抗O 对肝细胞损伤的作用。

 
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