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oncogene p
相关语句
  抑癌基因p16
     Expression and significance of P21 oncogene,P16 antioncogene in bladder cancer
     抑癌基因P16与癌基因P21在膀胱肿瘤中的表达及意义
短句来源
     Purpose:Find the relationship between the expressions of P21 oncogene,P16 antioncogene and the biological action of the bladder cancer.
     目的 :探讨癌基因 P2 1和抑癌基因 P16的表达与膀胱癌生物学行为之间的关系。
短句来源
     Methods:Using immunnohistochemical S P method,We examined exprossion of the P21 oncogene,P16 antiocogene in 40 cases of bladder cancer.
     方法 :采用免疫组织化学 S- P法对 40例膀胱移行细胞癌癌基因 P2 1和抑癌基因 P16进行检测。
短句来源
     Objective To investigate the expression of anti oncogene P 16 and proliferative cell nuclear antigen (PCNA) in esophageal squamous cell cancer and their clinical pathology.
     陕西省肿瘤医院 ,西安  71 0 0 612 陕西省人民医院 ,西安  71 0 0 68目的 观察抑癌基因P16、增殖细胞核抗原PCNA在食管鳞状细胞癌中的表达特性及与临床病理联系。
短句来源
     Objective To study the relationship between oncogene P16 and clinical pathological character of colorectal carcinoma Methods Expression of P16 in colorectal carcinoma, heterotypic hy-Perplasia of mucosa, inflammation and normal tissues were measured by immunohistochemistry SABC method.
     目的探讨抑癌基因P16与大肠癌的发生及临床病理特征之间的关系。 方法采用SABC免疫组化技术检测大肠癌、大肠黏膜腺瘤伴异型增生、炎症及正常组织中P16蛋白的表达。
短句来源
  “oncogene p 16”译为未确定词的双语例句
     On the contrary, the positive expression rate of suppressive oncogene p16 in control group was the highest as compared with the lowest results in Dys rats.
     而 p16蛋白表达则相反 ,在假手术对照组最高 ,在异型增生最低 ,两组之间差异有显著性 (P <0 .0 1) ,p16在异型增生时为低表达。
短句来源
  相似匹配句对
     Oncogene Antioncogene and Cancer
     癌基因、抗癌基因与癌
短句来源
     THE ras ONCOGENE PRODUCTS AND THE CARCINOMA
     ras癌基因产物与肿瘤
短句来源
     c erbB Proto oncogene and Psoriasis
     c-erbB原癌基因与银屑病
短句来源
     There were 9 oncogene and anti-oncogene;
     其中:原癌基因和抑癌基因9条;
短句来源
     (16) D.
     ⒃马毛虱D.
短句来源
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An expression of ras oncogene protein (p21) was assessed with immunohistochemistry in normal, dysplasia, benign hyperplasia, chronic prostatitis and prostatic carcinomatous tissues. The results showed that the positivity rate of p21 was higher in prostatic carcinoma than that in other prostatic lesions and was markedly correlated to histologic tumor grade. The expression level of p21 was more intentive in prostatic dysplasia surrounding carcinoma than that in simple prostatic dysplasia. It...

An expression of ras oncogene protein (p21) was assessed with immunohistochemistry in normal, dysplasia, benign hyperplasia, chronic prostatitis and prostatic carcinomatous tissues. The results showed that the positivity rate of p21 was higher in prostatic carcinoma than that in other prostatic lesions and was markedly correlated to histologic tumor grade. The expression level of p21 was more intentive in prostatic dysplasia surrounding carcinoma than that in simple prostatic dysplasia. It is suggested that overexpression of ras oncogene p21 product may play an important role in progressing from dysplasia to cancer and may be used as a new tumor marker for assessment of biological behavior of prostatic carcinoma.

用抗ras癌基因蛋白质产物p21单克隆抗体SCI-oncogema I,采用常规ABC免疫组织化学方法检测了66例前列腺癌、46例前列腺非典型增生、20例慢性前列腺炎、50例良性前列腺增生和6例正常前列腺组织石蜡标本中p21的表达,结果显示,前列腺癌的阳性表达率明显高于其他几组病变(P<0.01),其阳性表达率随肿瘤组织学分级增高而增高。前列腺癌周的不典型增生组织对p21的反应强度显著高于单纯性不典型增生组织。上述结果说明,ras癌基因产物p21的过量表达,在前列腺非典型增生向前列腺癌的发展过程中起着重要作用,并且可以作为一种新的肿瘤标记物来估计前列腺癌的生物学行为。

he oncogene P21 ̄(ras) expression in premalignant lesions and carcinomas of the stomach was quantitatively studied by flow cytometry and immunofluorescence methods and the relation of P21 ̄(ras) to DNA ploidy and cellular proliferation was analysed.The results showed that P21 ̄(ras) expression was high- er in carcinomas than premalignant lesions of the stomach.The fluorescence index in P21 ̄(ras) expression increased with the rise in histological grade. DNA ploidy correlated with the amount...

he oncogene P21 ̄(ras) expression in premalignant lesions and carcinomas of the stomach was quantitatively studied by flow cytometry and immunofluorescence methods and the relation of P21 ̄(ras) to DNA ploidy and cellular proliferation was analysed.The results showed that P21 ̄(ras) expression was high- er in carcinomas than premalignant lesions of the stomach.The fluorescence index in P21 ̄(ras) expression increased with the rise in histological grade. DNA ploidy correlated with the amount of P21 ̄(ras) expression.

应用流式细胞术和细胞免疫荧光染色技术,对胃癌前病变和胃癌细胞P21 ̄(ras)的表达量进行了定量研究,并分析了P21 ̄(ras)的表达量与DNA倍体和细胞增殖指数的关系。结果表明:胃癌细胞P21 ̄(ras)表达量(荧光指数FI)明显高于胃癌前病变的表达量,并发现P21 ̄(ras)表达的荧光指数随组织学分级增高而升高,DNA倍体与P21 ̄(ras)表达量有密切关系。

When human Bel-7402 hepatocarcinoma cell line grew in a medium containing 10-4M DDB,the secretion of α-fetoprotein(AFP) and the activity of γ-glutamyltranspeptidase(γ-GT)were significantly lower than the control cells,whereas the albumin(ALB) secretion and the activity of tyrosine-α-ketoglutarate transaminase(TAT)were markedly increased.DDB at the concentration of 10-4M could significantly increase the content of cAMP in Bel-7402 cells,and also suppressed the expressions of oncogene c-myc and hepatocarcinoma...

When human Bel-7402 hepatocarcinoma cell line grew in a medium containing 10-4M DDB,the secretion of α-fetoprotein(AFP) and the activity of γ-glutamyltranspeptidase(γ-GT)were significantly lower than the control cells,whereas the albumin(ALB) secretion and the activity of tyrosine-α-ketoglutarate transaminase(TAT)were markedly increased.DDB at the concentration of 10-4M could significantly increase the content of cAMP in Bel-7402 cells,and also suppressed the expressions of oncogene c-myc and hepatocarcinoma marker AFP gene and enhanced the anti-oncogene p53 expression.The results of this paper suggest that DDB has some reversing effects on the phenotypes of human Bel7402 hepatocarcinoma cell line.

作者运用生化和分子生物学方法,探讨了抗肝炎药联苯双酯(DDB)对人肝癌细胞分化的影响,结果发现:生长在含有10-4mol/LDDB培养液中的人肝癌Bel-7402细胞,其甲胎蛋白(AFP)的分泌量和γ-谷氨酰转肽酶(γ-GT)活力均明显低于培养相同天数的对照细胞,而白蛋白(ALB)的分泌量和酪氨酸-α酮戊二酸转氨酶(TAT)活性又明显高于对照细胞。DDB还能明显增加Bel/7402细胞环化腺苷酸(cAMP)的含量,并抑制癌基因c-myc及肝癌标志AFP基因的表达,增强了P53抑癌基因的表达。上述结果提示DDB能诱导人Bel-7402肝癌细胞的分化。

 
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