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endothelin
相关语句
  内皮素
    Determination of Platelet-Granular Membranous Protein and Endothelin in Blood Stasis Patient
    血瘀证患者血小板α—颗粒膜蛋白、内皮素测定
短句来源
    The clinical symptoms and signs, hemodiastase, urinary amylase, C-reactive protein (CRP) and endothelin (ET) of the patients in the two groups before and after treatment were observed and detected.
    治疗前及治疗第7天作血、尿淀粉酶及血C反应蛋白(C-reactive protein,CRP)、内皮素(endothelin,ET)水平检测。
短句来源
    Objective: To investigate the effect of Shenfu Injection(SFI,参附注射液) on plasma endothelin (ET) and nitric oxide(NO) levels in patients with severe acute pancreatitis(SAP),and the mechanisms.
    目的观察参附注射液(SFI)对重症急性胰腺炎(SAP)患者血浆内皮素(ET)、一氧化氮(NO)的影响及对SAP的治疗作用,并探讨其机制。
短句来源
    Methods: 127 patients with cerebral arteriosclerotic headache aged 50 to 75 were randomly divided into therapeutic group and control group, the therapeutic efficacy and concentration of serum nitric oxide (NO), calcitonin geng-related peptide (CGRP), endothelin (ET) ,β-endorphin (β-EP) and average velocity of cerebral blood flow (VM) were measured.
    方法:127名脑动脉硬化性头痛患者随机分为治疗组和对照组,观察疗效、TCD及血浆一氧化氮(NO)、降钙素基因相关肽(CGRP)、内皮素(ET)和β-内啡肽(β-EP)水平的变化。
    Clinical Study on Improving Effect of Buyang Huanwu Decoction on Plasma Thromboxane B_2, 6-Keto-Prostaglandin F_(1α), Endothelin and Calcitonin Gene Related Peptide in Primary Nephrotic Syndrome Patients
    补阳还五汤对原发性肾病综合征患者血浆血栓素B_2、6-酮-前列腺素F_(1α)、内皮素、降钙素基因相关肽改善作用的研究
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  “endothelin”译为未确定词的双语例句
    Study on Levels of Plasma Endothelin and Nitrii Oxide in Patients with Unstable Angina and lnfluence of Chinese Herbal Medicine
    Study on Levels of Plasma Endothelin and Nitrii Oxide in Patients with Unstable Angina and lnfluence of Chinese Herbal Medicine
短句来源
    Effect of Puerarin on Plasma Endothelin, Renin Activity and Angiotensin Ⅱ in Patients with Acute Myocardial infarction
    Effect of Puerarin on Plasma Endothelin, Renin Activity and Angiotensin Ⅱ in Patients with Acute Myocardial infarction
短句来源
    Study on Plasma Endothelin, Angiotensin II, Thromboxame A_2 in Different TCM Type of Grade 2 Hypertension and Effect of Tetrametuyl Pyrazine
    2级高血压病中医证型与血浆ET、AngⅡ、TXA_2关系及川芎嗪的影响
短句来源
    Effect of Tangzu Prescription for the Treatment of Diabetic Foot and Its Influence on Plasma NO,Endothelin and Vascular Endothelial Growth Factor
    糖足方治疗糖尿病足及其对血浆NO、ET、VEGF的影响
短句来源
    4.High-dose of Qingrezhixuening can increase endothelin expression in endometrium;
    4.免疫组化结果表明,清热止血宁高剂量组能增强子宫内膜ET阳性表达。
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  endothelin
Cardiovascular and Urinary System Receptors: Focus on Endothelin Receptor and α1-Adrenoceptor Subtypes
      
The study of substrate specificity of a new peptide substrate of endothelin-converting enzyme
      
A new hexapeptide CMC-Ala-Gly-Gly-Trp-Phe-Arg was used as a substrate for assay of endothelin-converting (ECE; EC 3.4.24.71) and angiotensin-converting (ACE; EC 3.4.15.1) enzymes and of neutral endopeptidase (NEP; EC 3.4.24.11).
      
The expression of endothelin type A and B receptors in the lateral wall of the mouse cochlea
      
Endothelin (ET), originally characterized as a vasoconstrictive peptide, has been found to have many different biological functions, including acting as a local hormonal regulator of pressure, fluid, ions and neurotransmitters in the inner ear.
      
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The experiment was designed to elucidate the effect of Oenotheria binnis Seed Oil (OBSO) on experimental hyperlipidemia in rats. The contents of serum lipids, lipoperoxides (LPO), plasma superoxides dismutase (SOD), thromboxane (TXA 2), prostacyclin (PGI 2), endothelin (ET) and the ultrastructural pathological change of the aortic wall under the scanning electron microscope were observed. Hyperlipidemic Wistar rats were fed with high fat diets (HFD) containing OBSO (2%) for 4 weeks. The results...

The experiment was designed to elucidate the effect of Oenotheria binnis Seed Oil (OBSO) on experimental hyperlipidemia in rats. The contents of serum lipids, lipoperoxides (LPO), plasma superoxides dismutase (SOD), thromboxane (TXA 2), prostacyclin (PGI 2), endothelin (ET) and the ultrastructural pathological change of the aortic wall under the scanning electron microscope were observed. Hyperlipidemic Wistar rats were fed with high fat diets (HFD) containing OBSO (2%) for 4 weeks. The results showed that: OBSO could reduce the level of total serum cholesterol (TC) and triglyceride (TG), and increase the level of high density lipoprotein cholesterol (HDL C). OBSO could significantly reduce serum LPO level and markedly increase plasma SOD activities. The concentration of plasma PGI 2 in the group fed with OBSO was much higher than that in the group fed with HFD only, meanwhile the concentration of plasma ET and the ratio of TXA 2/PGI 2 in OBSO were lower than those in HFD group. Moreover, hepatic histopathological examinations showed that hepatic fat accumulation in OBSO group was less than that in HFD group. OBSO could attenuate the damage of aortic endothelium. These results indicate that OBSO is useful in treating hyperlipidemia, protecting endothelial cells and preventing atherosclerosis.

用含2%月见草油的高脂饲料喂饲实验性高脂血症大鼠4周,分别对血脂、血清脂质过氧化物(LPO)、血浆超氧化物歧化酶(SOD)、血栓素(TXA2)、前列腺素(PGI2)及内皮素(ET)进行了检测,并用扫描电镜对动脉内皮进行了观察。结果发现:月见草油能降低血清总胆固醇(TC)及甘油三酯(TG)含量,提高高密度脂蛋白胆固醇(HDL-C)含量;月见草油能显著降低血清LPO水平,提高血浆SOD活力;月见草油组大鼠血浆PGI2水平明显增高,而TXA2/PGI2比值及血浆ET水平明显下降;月见草油组大鼠肝脏脂肪蓄积稍轻于高脂对照组;扫描电镜观察亦发现月见草油组大鼠动脉内皮损伤明显轻于高脂对照组。结果提示月见草油具有良好的降脂、保护内皮细胞及预防动脉粥样硬化形成的作用

Ninety cases of angina pectoris patients with the Deficiency of Heart Qi Syndrome(DHQS),Deficiency of Heart-Yin Syndrome(DHYS) and blood stasis in Heart vessels Syndrome(BSHVS)were studied. The number of patients were 30 for each group. Their regulatory polypeptides:atrial natri-uretic polypeptide(ANP),β-Endorphine(β-EP),Endothelin(ET),Angiotensin (A-Ⅱ) weretested. Results showed that in comparing with normal level,p <0 . 05 or<0 . 01, ANP and -βEP of them:DHQS> BSHVS>normal group> DHYS. ET and A-Ⅱ of...

Ninety cases of angina pectoris patients with the Deficiency of Heart Qi Syndrome(DHQS),Deficiency of Heart-Yin Syndrome(DHYS) and blood stasis in Heart vessels Syndrome(BSHVS)were studied. The number of patients were 30 for each group. Their regulatory polypeptides:atrial natri-uretic polypeptide(ANP),β-Endorphine(β-EP),Endothelin(ET),Angiotensin (A-Ⅱ) weretested. Results showed that in comparing with normal level,p <0 . 05 or<0 . 01, ANP and -βEP of them:DHQS> BSHVS>normal group> DHYS. ET and A-Ⅱ of them:DHYS> BSHVS>normal group > DHQS,And the comparison between groups revealed that P < 0 . 05 or < 0 . 0 1 . So ANP,β-EP,ET and A-Ⅱ were the principal material basis, and they could be the specific objective parameters of the Syndrome Differentiation.

对90例不同证型冠心病心绞痛患者血浆心钠素(ANP)、β-内啡肽(β-EP)、内皮素(ET)、血管紧张素Ⅱ(A-Ⅱ)等调节肽指标进行临床检测,结果与30例正常人比较,均有显著性差异(P<0.05,P<0.01)。且舒血管作用的ANP和β-EP检测结果呈现心气虚证组>心脉瘀阻证组>正常人组>心阴虚证组,且实验观察组3组间两两比较,均有显著性差异(P<0.01)。而缩血管作用的ET、A-Ⅱ检测结果则呈现心阴虚证组>心脉瘀阻证组>正常人组>心气虚证组,且实验观察组3组间两两比较,均有显著性差异(P<0.01)。提示ANP、β-EP、ET、A-Ⅱ等调节肽是冠心病心绞痛临床辨证的主要物质基础之一,似可作为客观化辨证的特异性指标。

The Yuxintong (YXT) capsule, which possesses effects of removing blood stasis and replenishing Qi, was used to treat patients with unstable angina (UA).Sixty-five patients were divided randomly into YXT group (34 cases) and control groups (31 cases). Conventional Western medicine therapy was given to both groups and YXT was given to YXT group in addition. Results showed that: (1)Effect of YXT group was superior to that of control group in general clinical efficacy,recovery of ischemic S-T segment changes in...

The Yuxintong (YXT) capsule, which possesses effects of removing blood stasis and replenishing Qi, was used to treat patients with unstable angina (UA).Sixty-five patients were divided randomly into YXT group (34 cases) and control groups (31 cases). Conventional Western medicine therapy was given to both groups and YXT was given to YXT group in addition. Results showed that: (1)Effect of YXT group was superior to that of control group in general clinical efficacy,recovery of ischemic S-T segment changes in electrocardiogram, improvement of grading of angina,reduction in consumption of nitroglycerine, and mean onset time of effect. Meanwhile, the subjective symptoms and signs of blood stasis also improved evidently. (2)Laboratory findings displayed obvious elevation of peripheral circulatory endothelial cells, plasma endothelin (ET), malonyldialdehyde and α-granule membrane protein-140, as well as markedly reduction of erythrocyte superoxide dismutase and glutathione peroxidase activity,P<0 . 01~0. 001. The effect of YXT group was significantly better than that of control group,P< 0. 05~0 .01. These findings suggested that YXT could supplemented Western medicine of antiangina, it might act by means of improving the function of vascular endothelia, antagonising against ET, inhibiting the platelet activation and reducing the damage induced by lipid peroxidation.

本研究观察了益气活血方药愈心痛胶囊配合常规西药治疗34例不稳定性心绞痛(UA)的临床疗效。结果显示:(1)愈心痛组在总的临床疗效方面和在心电图缺血性ST段恢复、心绞痛分级改善、硝酸甘油消耗量减少以及平均起效时间上均明显优于西药对照组(总有效率分别为94.1%和74.2%,P<0.05);同时,患者的自觉症状和血瘀征象也明显好转。(2)实验室检测表明,UA患者较正常对照组,外周血循环内皮细胞(CEC)数量及血浆内皮素(ET)、丙二醛(MDA)和α-颗粒膜蛋白(GMP-140)浓度显著增高,而红细胞超氧化物歧化酶(SOD)和全血谷胱甘肽过氧化物酶(GSH-Px)活性显著降低,提示UA患者存在严重的内皮功能损伤,体内血小板活化程度较高及抗脂质过氧化能力下降。给予愈心痛治疗2周后,血中CEC数量及ET、MDA和GMP-140含量均显著降低,而SOD、GSH-Px活性显著升高(P<0.01~0,001),疗效明显优于西药对照组(P<0.05~0.01)。提示愈心痛胶囊与抗心绞痛西药有协同治疗作用,可能是通过改善血管内皮功能,拮抗ET,抑制血小板活化和减轻脂质过氧化损伤等途径来达到治疗UA的目的。

 
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