助手标题  
全文文献 工具书 数字 学术定义 翻译助手 学术趋势 更多
查询帮助
意见反馈
   rb-gene protein 在 肿瘤学 分类中 的翻译结果: 查询用时:0.059秒
图标索引 在分类学科中查询
所有学科
肿瘤学
更多类别查询

图标索引 历史查询
 

rb-gene protein
相关语句
  rb蛋白
    The significance of Rb-gene protein expression in gastric cancers and adjacent tissue of gastric carcinoma
    Rb蛋白在胃癌及癌旁组织中表达的意义
短句来源
    Objectives To detect the expression and distribution of Rb-gene protein in adjacent tissue of cancers and gastric carcinoma tissues.
    目的 检测Rb蛋白在胃癌组织、癌旁组织中的表达及其分布特点。
短句来源
    Rb-gene protein expression were not related to age, sex and tumor position, but were significantly correlated with histological type, invasion depth, lymph node metastasis and clinical pathological stage.
    胃癌Rb蛋白表达与性别、年龄、肿瘤部位在统计学上无差异 (P >0 .0 5 ) ; 而与组织学类型、病理分级、淋巴结转移、临床病理分期在统计学上有差异 (P <0 .0 5 )。
短句来源
查询“rb-gene protein”译词为用户自定义的双语例句

    我想查看译文中含有:的双语例句
例句
没有找到相关例句


Immunohistochemical staining method(ABC method) is used to detect the Bcl 2,P53,P21 and Rb gene protein in 40 cases of primary brain gliomas and 5 cases brain tissue.Results showed:the positive rates of Bcl 2 protein,P53 protein expression were remarkably different in I to Ⅳ stage of brain gliomas.The expression of P21 protein,Rb protein was gradually increased from Ⅰ to Ⅳ stage of brain gliomas.Therefore our data ...

Immunohistochemical staining method(ABC method) is used to detect the Bcl 2,P53,P21 and Rb gene protein in 40 cases of primary brain gliomas and 5 cases brain tissue.Results showed:the positive rates of Bcl 2 protein,P53 protein expression were remarkably different in I to Ⅳ stage of brain gliomas.The expression of P21 protein,Rb protein was gradually increased from Ⅰ to Ⅳ stage of brain gliomas.Therefore our data indicated the Bcl 2,P53,P21 and Rb gene were important in arising of gliomas,particularly Bcl 2,P53 gene.The expression of these gene were correlated with the degree of malignant of gliomas.Detection of expression of Bcl 2,P53,P21 and Rb gene may be a useful tool for diagnosis,distinguish diagnosis and asserted of malignant and prognosis.

采用原癌基因Bcl-2、P21及抑癌基因P53、Rb蛋白4种抗体,用ABC免疫组织化学方法对40例脑星形胶质瘤组织作免疫组化染色.结果发现:Bcl-2及P53基因表达在Ⅰ~Ⅳ级胶质瘤中阳性率有显著性差异,而且染色强度也有明显差异.P21、Rb基因表达在Ⅰ~Ⅳ级胶质瘤中呈上升趋势,但仅在Ⅰ~Ⅲ级、Ⅰ~Ⅳ级之间有明显差异.可以认为:Bcl-2、P53、P21、Rb在胶质瘤的发生中发挥一定的作用,尤其是Bcl-2、P53基因,这些基因蛋白的表达与胶质瘤恶性程度有关.测定胶质瘤中的Bcl-2、P53、P21、Rb蛋白对于胶质瘤的诊断、鉴别诊断以及判断肿瘤的恶性程度与预后均有一定意义.

Objective To find the expression and significance of gene changes which were related to cell - cycle regulato in gastric candia carcinma.Methods The immunohistochemical mehod(SP)was used to study the expression of p16and Rb proteins in 58 cases of gastric cardea carcinoma. Results For p16, the positive rates decreased with the progression ofthe pathological grade and invasion, while for Rb, the positive rates increased (P < 0.05). There was an inverse relationshipbetween the expression of p16 and...

Objective To find the expression and significance of gene changes which were related to cell - cycle regulato in gastric candia carcinma.Methods The immunohistochemical mehod(SP)was used to study the expression of p16and Rb proteins in 58 cases of gastric cardea carcinoma. Results For p16, the positive rates decreased with the progression ofthe pathological grade and invasion, while for Rb, the positive rates increased (P < 0.05). There was an inverse relationshipbetween the expression of p16 and Rb gene protein (P < 0.05). Conclusion These results suggest that deletion of p16 andRb gene Protein expession is related with carcinogenesis of gastric cardia carcinoma, and Rb expression is negatively regulated by the functional of p16 gene protein.

目的探讨与细胞周期调节相关的基因p06和Rb基因在贲门癌中的表达及其意义。方法用SP免疫级化法对58例贲门癌进行p16和Rb基因蛋白的检测。结果随着贲门癌恶性程度的加重和浸润的加深,p16基因蛋白的阳性表达率逐渐降低,而Rb基因蛋白的阳性表达率逐渐升高(P<0.05)。p16和Rb基因蛋白的表达呈显著负相关(P<0.05)。结论p16和Rb基因蛋白的表达异常在贲门癌的发生发展中起重要作用。p16基因蛋白对Rb基因蛋白的表达具有负性调节作用。

Objective: To detemine the relationship between the expression of MTS1/p16, p53, Rb gene protein or proliferating cell nuclear antigen( PCNA) and clinicopathologic of human gastric cancer. Methods: Using SP immunohistochemical methods, p16, p53, Rb and PCNA expression were detected in 63 specimens of gastric carcinoma. Results:The positive expressions for p16, p53, Rb and PCNA were 63.5% , 60.3% , 65.6% and 71.4%, respectively. For p16, the positive rates decreased with the progression of the...

Objective: To detemine the relationship between the expression of MTS1/p16, p53, Rb gene protein or proliferating cell nuclear antigen( PCNA) and clinicopathologic of human gastric cancer. Methods: Using SP immunohistochemical methods, p16, p53, Rb and PCNA expression were detected in 63 specimens of gastric carcinoma. Results:The positive expressions for p16, p53, Rb and PCNA were 63.5% , 60.3% , 65.6% and 71.4%, respectively. For p16, the positive rates decreased with the progression of the pathological grade and invasion,while for p53, Rb and PCNA,the positive rates increased .

目的:研究胃癌中 p16、 p53、 Rb蛋白及 PCNA表达与临床病理的关系。方法:应用免疫组化 SP法对 63例胃癌组织中 p16、 p53、 Rb和 PCNA进行检测。结果: 63例胃癌组织中 p16、 p53、 Rb蛋白和 PCNA表达阳性率分别为 63.5%、 60.3%、 65.6%和 71.4%。 p16蛋白阳性表达随着肿瘤分化程度降低、恶性程度增加和浸润深度的加深, 其表达的阳性率逐渐降低,而 p53、 Rb蛋白及 PCNA的表达则相反。 p16与 p53、 Rb蛋白表达有明显负相关。结论: p16和 p53、 Rb基因蛋白和 PCNA的检测可作为判断胃癌恶性程度、预测肿瘤转移和预后的参考指标。

 
<< 更多相关文摘    
图标索引 相关查询

 


 
CNKI小工具
在英文学术搜索中查有关rb-gene protein的内容
在知识搜索中查有关rb-gene protein的内容
在数字搜索中查有关rb-gene protein的内容
在概念知识元中查有关rb-gene protein的内容
在学术趋势中查有关rb-gene protein的内容
 
 

CNKI主页设CNKI翻译助手为主页 | 收藏CNKI翻译助手 | 广告服务 | 英文学术搜索
版权图标  2008 CNKI-中国知网
京ICP证040431号 互联网出版许可证 新出网证(京)字008号
北京市公安局海淀分局 备案号:110 1081725
版权图标 2008中国知网(cnki) 中国学术期刊(光盘版)电子杂志社