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gene upstream regulation sequence
相关语句
  基因上游调控序列
     Objective To appraise the relationship between fluconazole resistance and expression of the CDR1 gene upstream regulation sequence.
     目的探讨白念珠菌耐药基因CDR1基因上游调控序列对氟康唑耐药的影响。
短句来源
  相似匹配句对
     was found in the 5' upstream of the CD2 gene.
     CD2基因具有弱启动子、强增强子的特点与T细胞表面其它抗原分子基因是相似的。
短句来源
     GETTING UPSTREAM GENE REGULATORY AREA BY SPM
     SPM法获取基因上游调控序列
短句来源
     Promoter sequence of the gene's upstream was forecasted by bioinformatic method.
     结合生物信息学方法分析预测基因上游的启动子序列。
短句来源
     METHODS: The upstream regulation sequences of amelogenin gene were retrieved and analyzed.
     方法:检索并分析釉原蛋白基因的上游调控序列。
短句来源
     Gene Sequences
     基因序列(英文)
短句来源
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Objective To appraise the relationship between fluconazole resistance and expression of the CDR1 gene upstream regulation sequence. Methods The DNA of fluconazole-susceptible and fluconazole-resistant Candida albicans isolates were extracted, PCRs were based on the special primer of upstream regulation sequence of Candida albicans CDR1 gene, and the mutation of the sequence was compared by DNA sequencing. Results No mutation was found in the upstream regulation...

Objective To appraise the relationship between fluconazole resistance and expression of the CDR1 gene upstream regulation sequence. Methods The DNA of fluconazole-susceptible and fluconazole-resistant Candida albicans isolates were extracted, PCRs were based on the special primer of upstream regulation sequence of Candida albicans CDR1 gene, and the mutation of the sequence was compared by DNA sequencing. Results No mutation was found in the upstream regulation sequence of Candida albicans CDR1 gene. Conclusions Candida albicans fluconazole resistance is not due to mutation of the upstream regulation sequence of Candida albicans CDR1 gene.

目的探讨白念珠菌耐药基因CDR1基因上游调控序列对氟康唑耐药的影响。方法分别抽提氟康唑耐药/敏感配对菌株DNA,通过特异性合成CDR1基因上游调控序列引物,分析该序列在氟康唑耐药/敏感配对菌株中是否存在基因突变。结果白念珠菌氟康唑耐药/敏感配对菌株中的CDR1基因上游调控序列未出现任何碱基突变和缺失。结论白念珠菌氟康唑耐药与CDR1基因上游调控序列是否突变无关。

 
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