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hematopoietic
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  造血
     Experimental Studies on the Function of Ndr2 in Human Lymphoid Hematopoietic Tissues
     Ndr2基因在人类淋巴造血系统中的功能研究
短句来源
     Study on Clinic and Serum Hematopoietic Regulator IL-6、TGF-β_1、Bone Marrow C-Kit、CXCR_4 Receptor of CAA with Marrow-Supplementing and Blood-Engendering Granule
     补髓生血颗粒剂治疗慢性再生障碍性贫血及对血清造血调控因子IL-6、TGF-β_1及骨髓c-kit、CXCR_4受体影响的研究
短句来源
     Notch Signaling Promotes Expansion of Hematopoietic Stem/Progenitor Cells and Osteogenic Differentiation of Mesenchymal Stem Cells
     Notch信号促进造血干/祖细胞扩增及间充质干细胞向成骨细胞分化的研究
短句来源
     Novel Chemokine MIP-2γ Maintains Survival, Promotes Chemotaxis and Increases Mobilization of Hematopoietic Stem Cells: Effects and Mechanisms
     新型趋化因子MIP-2γ对造血干/祖细胞的存活、趋化和动员作用及机制研究
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     Bone Marrow Endothelial Cell-conditioned Medium Inducing Hematopoietic Differentiation of Mouse Embryonic Stem Cells
     骨髓内皮细胞条件培养液诱导胚胎干细胞向造血细胞分化
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  “hematopoietic”译为未确定词的双语例句
     Study on Hematopoietic Constituents in SI-WU-TANG by Chemomics Method
     用化学组学方法研究四物汤的补血成分
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     Application of Microsatellite Markers in Allogeneic Hematopoietic Stem Cell Transplantation
     微卫星标志物在异基因造血干细胞移植中的应用
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     The Experimental Studies of vIL-10 Gene Transfer of Hematopoietic Stem Cells Induce Tolerance to Murine Cardiac Allograft
     vIL-10基因修饰造血干细胞诱导小鼠心脏移植免疫耐受的实验研究
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     Experimental Study on Isolation, Cultivation of Human Embryonic Germ Cells in Vitro and Committed Differentiation of Hegcs to Hematopoietic Cells
     人EG细胞分离、培养及其定向诱导为造血细胞的实验研究
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     Endothelial Splenic Stroma Cells Program Hematopoietic Stem Cells to Differentiate into Regulatory Dendritic Cells
     内皮型脾脏基质细胞诱导造血干细胞分化为调节性树突状细胞
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  相似匹配句对
     On Antigenicity of Hematopoietic Stem Cells
     造血干细胞抗原的研究
短句来源
     STUDIES ON CRYOPRESERVATION OF HEMATOPOIETIC CELLS
     造血细胞低温保存的研究
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  hematopoietic
Experimental study on ex vivo expanded hematopoietic stem/progenitor in the two step culture from human umbilical cord blood tra
      
The effects of hematopoietic stem/progenitor cells (HSPCs) expanded in the two step coculture with human bone marrow mesenchymal stem cells (hMSCs) on the hematopoietic reconstruction of irradiated NOD/SCID mice were studied.
      
Isolation and cultivation of murine hematopoietic stem cells and expression of hFIX mediated by recombinant lentiviral vectors i
      
Hematopoietic stem cells (HSCs) are an attractive target for gene therapy, especially for inherited blood diseases.
      
It is also indicated that the hematopoietic stem cells may give rise to some HSCs in embryonic liver.
      
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Harringtonine (HA) and homoharringtonine (HO), two new antileukemic agents, were submitted to toxicological studies in mice, rabbits and dogs. The major target organs involved in toxicity in rabbits and dogs produced by 5 or 7 day treatments with either alkaloid were limitted to G. I. tract, heart and hematopoietic organs. Most deaths were attributable to cardiac dysfunction. After injection of lethal doses, hepatic and renal toxicities of mild to moderate degree occurred only in individual cases. When...

Harringtonine (HA) and homoharringtonine (HO), two new antileukemic agents, were submitted to toxicological studies in mice, rabbits and dogs. The major target organs involved in toxicity in rabbits and dogs produced by 5 or 7 day treatments with either alkaloid were limitted to G. I. tract, heart and hematopoietic organs. Most deaths were attributable to cardiac dysfunction. After injection of lethal doses, hepatic and renal toxicities of mild to moderate degree occurred only in individual cases. When such treatments were repeated for two additional courses, no additional significant toxicity was observed. However, the cardiac and hematopoietic toxicity appeared to be moderately cumulative. All toxicities observed were dose-dependent, predictable and completely reversible upon discontinuation of treatment. No significant delayed toxicity was noted during an observation period of 6 weeks or more. Neither inter or intraspecies nor sex related differences in qualitative toxicity of either HA or HO were observed. 0.42 mg/kg/d×5 of HA and 0.16 mg/kg/d×7 of HO were established as the toxic doses high for dogs. The LD_(50) S (±S·E) of HA and HO in mice (I. P.) were found to be 4.17±0.30 and 3.17±0.19 mg/kg, respectively. Although He was found to be more potent than HA, qualitatively the two alkaloids did not differ significantly.

用小鼠、兔及犬研究了三尖杉酯碱(HA)和高三尖杉酯碱(HO)的毒性。兔及犬连续给药五或七天,两药毒性的主要靶器官都是胃肠道、心脏和造血器官。大多数毒性死亡皆可归因于心功能障碍。用致死剂量时,尚个别出现轻、中度肝、肾损害。间歇地重复给药共三疗程,未出现其它重大毒性,但心脏及造血显示为轻、中度累积性的毒性,毒性与剂量大小平行,可及时发现,停药后是完全可逆的。在至少六周的观察期内未见重大迟发毒性,两药均未见种属间、个体间或与性别有关的毒性性质上的显著差异。HA及HO的家犬中毒剂量(高)分别是0.45mg/kg/天×5及0.16mg/kg/天×7。小鼠急性LD_(50)(±S.E.)分别是4.17±0.30及3.17±0.19mg/kg。HA与HO相比,两者毒性在性质上无重大差别,程度上则HO显著大于HA。

The haemorrhagic disease of the grass carp is a wide-spread viral disease infingerling fishfarms, and it may seriously endanger the production of fingerling grasscarp. In order to make further studies on the causative agent of this disease, electronmicroscopic observations were performed on the artificially infected kidney. Theresults of the observations are reported in this paper. During 1976 and 1977, the ultra-thin sections of the kidney tissue of grass carpfingerlings (1.5-2.5 cm in total length) from three...

The haemorrhagic disease of the grass carp is a wide-spread viral disease infingerling fishfarms, and it may seriously endanger the production of fingerling grasscarp. In order to make further studies on the causative agent of this disease, electronmicroscopic observations were performed on the artificially infected kidney. Theresults of the observations are reported in this paper. During 1976 and 1977, the ultra-thin sections of the kidney tissue of grass carpfingerlings (1.5-2.5 cm in total length) from three normal fish and seven moribundfish which had typical symptoms of the haemorrhagic disease after being exposed tothe causative agent were examined under electron microscope. Virus particles wereobserved in the kidney tissue of the infected fish; some of the particles were presentedas crystalline structures and orderly arranged. Similar particles were also found inthe head kidney. The virus particles similar to those of infected fish were not observedin the kidney tissues of normal fish. The observed virus was in the shape of spherical or hexagonal particles. 109 ofthese particles had a size ranging from 60 to 78 nm and a mean of 69 nm in diameter.They consisted of an outer coat 20 nm thick and a core with high electronic densityapproximately 32 nm in diameter. Another kind of virus particles was found in thecell nucleus and cytoplasmic inclusion bodies. These particles were devoid of an outercoat and had a size from 46-60 nm in diameter, average 52 nm. All such virus par-ticles were only observed in the hematopoietic tissue of the kidney, but have not beenobserved in the erythrocytes and granulocytes. There was also an absence of virusparticles in the epithelium of uriniferous tubule, which presented a normal appearance. As compared with CCV, VHS, IHN and Rhabdovirus of the grass carp (RVGC).so far as virus appearance, optimal temperature fur replication and symptom ofinfected fish are concerned, this virus appears to be similar to CCV. But its averagediameter is only 69 nm while that of CCV is 100 nm. Therefore, the observed virusparticles are considered to be different from all other known viruses of fish, so thatwe tentatively designate it as Herpesvirus of Grass earp (HVGC).

在病鱼肾组织中发现有病毒颗粒,在头肾组织中也看到类似的颗粒。病毒呈球形或六角形,直径为60—78毫微米,平均为69毫微米;颗粒中央有一电子密度较高的核心,其直径平均为32毫微米,核心周围包有外膜,宽20毫微米左右。此外,还有一种无外膜的、电子密度均匀的病毒颗粒,直径为46—60毫微米,平均为52毫微米,这种颗粒出现在细胞核和胞质包涵体内。所观察到的病毒颗粒均出现在肾的造血组织内,但红血球和颗粒白血球中没有发现。肾小管上皮细胞正常,也未观察到病毒颗粒。在正常鱼的肾组织中没有发现与病鱼标本中类似的病毒颗粒。因此可以认为,我们人工感染致病的草鱼肾组织中所观察到的病毒颗粒,是草鱼出血病的病原,暂名为草鱼疱疹病毒。

After the investigation of 1,000 bone marrow biopsies, using the six staining procedures in every instance, i.e.,H.E., Giemsa,reticulin,collagen, PAS and Prussian blue reaction, the authors discuss the following ten aspects: the percentage of cellularity, the granulocytc to nucleated red blood cell ratio ( M : E ratio ) , the process of matura-tion of hematopoietic cells, the content of plasma cells, the content of megakaryocytes, edema and hemorrhage, the modification of reticulin fibres, the modification...

After the investigation of 1,000 bone marrow biopsies, using the six staining procedures in every instance, i.e.,H.E., Giemsa,reticulin,collagen, PAS and Prussian blue reaction, the authors discuss the following ten aspects: the percentage of cellularity, the granulocytc to nucleated red blood cell ratio ( M : E ratio ) , the process of matura-tion of hematopoietic cells, the content of plasma cells, the content of megakaryocytes, edema and hemorrhage, the modification of reticulin fibres, the modification of collagen fibres,the modification of bone trabeculae, and the evaluation of iron stores. In addition, some criteria for the basic lesions under microscopic observation are proposed.

根据1,000例骨髓穿刺活检及近二年来采用H.E.、姬姆萨、网状纤维、胶原纤维、PAS及铁反应6种染色后的工作体会,对一些基本病变的观察作了分析和探讨.共讨论了10个问题:如造血组织与脂肪组织的比例、粒细胞与红细胞的比例、造血细胞成熟过程、浆细胞含量、巨核细胞含量、骨髓水肿与出血、网状纤维的变化、胶原纤维的变化、骨小梁变化及骨髓中贮存铁的观察等,并对其中某些内容提出了自己镜检的常规标准.

 
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