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reactive lysis
相关语句
  反应性溶解
     Being cascade reaction, complement activation is strictly controlled by many regulators of complement activation. Among these regulators, membrane cofactor protein ( MCP),decay acceleration factor (DAF), membrane inhibitor of reactive lysis ( CD59,MIRL) are more effective.
     补体激活做为一种级联反应受到多种补体调节因子(Regulators of Complement Activation,RCA)的严格控制,这些调节因子中以膜辅助蛋白(MCP)、衰变加速因子(DAF)和膜反应性溶解抑制物(CD59、MIRL)的作用尤为显著。
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  “reactive lysis”译为未确定词的双语例句
     Objective:To study the significance of Decay Accelerating Factor(DAF=CD55)? Membrane Inhibitor of reactive Lysis (MIRL=CD59) in the diagnostic of paroxysmal nocturnal hemoglobinuria (PNH).
     目的 :探讨衰变加速因子 (CD5 5 )、反应性溶血膜抑制物 (CD5 9)在阵发性睡眠性血红蛋白尿(PNH)诊断中的意义。
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  相似匹配句对
     Reactive Perfume
     反应香料
短句来源
     I. reactive 261and C.
     I活性红261及C.
短句来源
     Knee adhesion lysis with arthroscope
     关节镜下松解膝关节粘连
短句来源
     pseudotuberculosis bacteriophage lysis test.
     ,用传统生化和噬菌体裂解实验证实。
短句来源
     Microassay for Determination of Reactive Hemolysis
     微量补体反应性溶血测定法
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  reactive lysis
Red cell proteins, decay accelerating factor, and membrane inhibitor of reactive lysis were found to be deficient.
      


Objective:To study the significance of Decay Accelerating Factor(DAF=CD55)?Membrane Inhibitor of reactive Lysis (MIRL=CD59) in the diagnostic of paroxysmal nocturnal hemoglobinuria (PNH). Methods: Flow cytometric analysis of CD55?CD59 was carried to detect the deficiency of membrane protein to the cell surface. Results: The level of CD55(45.94±6.06)%,CD59(46.40±12.36)% of PNH group was significantly lower than that of in AA-PNH CD55(71.00±0.43)%,CD59(84.62±2.08)%,in AA CD55(99.19±0.86)%,CD59(94.42±2.92)%...

Objective:To study the significance of Decay Accelerating Factor(DAF=CD55)?Membrane Inhibitor of reactive Lysis (MIRL=CD59) in the diagnostic of paroxysmal nocturnal hemoglobinuria (PNH). Methods: Flow cytometric analysis of CD55?CD59 was carried to detect the deficiency of membrane protein to the cell surface. Results: The level of CD55(45.94±6.06)%,CD59(46.40±12.36)% of PNH group was significantly lower than that of in AA-PNH CD55(71.00±0.43)%,CD59(84.62±2.08)%,in AA CD55(99.19±0.86)%,CD59(94.42±2.92)% and control group CD55(99.23±0.95)%,CD59(98.56±1.25)%.Conclusion: CD55 and CD59 is a useful target to diagnose and characterize PNH.

目的 :探讨衰变加速因子 (CD5 5 )、反应性溶血膜抑制物 (CD5 9)在阵发性睡眠性血红蛋白尿(PNH)诊断中的意义。方法 :用流式细胞仪检测CD5 5、CD5 9的表达量 (% )。结果 :PNH组CD5 5、CD5 9明显低于AA -PNH组和AA组、对照组。结论 :检测患者外周血粒细胞膜表面抗原CD5 5、CD5 9可作为PNH的早期确诊指标 ,其中CD5 9是较敏感指标 ,CD5 5是特异性指标。

Objective To form hemolytica membrane attack complex(MAC)with purified human terminal components of complement after activation of C5 with chloramine T(Cl T), a methionine oxidizing agent Methods Purified human C5 was incubated with Cl T in barbital buffer C6 was added to form a stable C56 complex 10 min later After incubation with NHS or purified C7, C8 and C9, MAC formation and lysis of non sensitized guinea pig red cells (reactive lysis) were assayed Results Cl T treated C5 acquired...

Objective To form hemolytica membrane attack complex(MAC)with purified human terminal components of complement after activation of C5 with chloramine T(Cl T), a methionine oxidizing agent Methods Purified human C5 was incubated with Cl T in barbital buffer C6 was added to form a stable C56 complex 10 min later After incubation with NHS or purified C7, C8 and C9, MAC formation and lysis of non sensitized guinea pig red cells (reactive lysis) were assayed Results Cl T treated C5 acquired a binding site for C6 to form C56; After it incubated with C6 and subsequent addition of NHS or C7, C8 and C9, a membrane attack complex was formed which lysed non sensitized guinea pig red cells The hemolytic activity was in a dose dependent fashion Conclusion Cl T oxidating C5 leads to form C5b like functional activity molecules which can bind to C6 and form hemolytic MAC

目的 利用氧化的方法在无酶解反应发生的情况下获得活化形式的C5 ,进而实现以纯化的补体终末成分体外组装补体膜攻击复合物 (MAC)。方法 以蛋氨酸氧化剂氯氨 T与纯化的C5相互作用后 ,加入C6组装具溶血活性的C5 6复合物。以此复合物与NHS或纯化的后续终末补体成分组装MAC ,检测复合物的溶血活性。结果 反应性溶破实验证实 ,氯胺 T氧化C5与C6组装形成功能C5 6复合物 ,后者可与NHS或纯化的补体终末成分C7~C9体外组装具溶血活性的MAC ,并且所形成的C5 6复合物在 2 4h达到最大的溶血活性 ,48h仍保持稳定。结论 氯胺 T在不裂解C5的条件下产生了C5b样活性分子 ,该分子能与C6组装形成稳定的活性复合物 ,并可与其它补体终末成分组装产生活性MAC。

 
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