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median infective dose
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  “median infective dose”译为未确定词的双语例句
     The median infective dose of medical urea immunoliposomes for HVEC was about 26 mg.
     尿素免疫脂质体对HVEC的半效应量(ID50)约26 mg。
短句来源
     The results showed that the potency was 5.2、(3.6)、2.1、1.0 PD_(50) per dose when using 500、1 000、2 000、4 000 ID_(50)which is the median infective dose as the challenge viral dosage, respectively.
     结果表明 ,分别用 5 0 0ID50 、10 0 0ID50 、2 0 0 0ID50 和 4 0 0 0ID50 的病毒进行攻毒 ,疫苗每头份分别含 5 .2、3.6、2 .1和 1.0个PD50 。
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  相似匹配句对
     The median infective dose of medical urea immunoliposomes for HVEC was about 26 mg.
     尿素免疫脂质体对HVEC的半效应量(ID50)约26 mg。
短句来源
     Modified Median Sternotomy
     改良胸骨正中切口
短句来源
     The recombinant adenovirus titers were tested with median tissue culture infective dose (TCID50) method.
     B.B DNA。 转染并荧光显微镜观察eGFP的表达,进行重组腺病毒的PCR鉴定,重组腺病毒扩增后氯化铯密度梯度离心法纯化Ad-VEGF_(165),TCID_(50) 50%组织培养感染剂量法,测定腺病毒滴度。
短句来源
     Infective Massive Hemobilia
     感染性胆道大出血
短句来源
     nov. Size median.
     nov.
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  median infective dose
Still, the dosage for tularemia is well above the median infective dose for almost two hours, giving reasonable time to cover most fixed targets.
      


The virulence of foot and mouth disease(FMD) virus of ORMF8 in type O used as the challenge virus when potency tests of porcine FMD vaccine was detected on pigs. The minimal infecting dose(MID) and the (median) infective dose(ID_(50)) were detected by three factories. The MID and ID_(50) determined by Lanzhou Veterinary (Research) Institute, Stock Lanzhou Biological Products Factory and Inner Mongolia Biological Products Factory of Jinyu Group were 10~(-6.0)/2 mL, 10~(-8.2)/2 mL; 10~(-7.0)/2...

The virulence of foot and mouth disease(FMD) virus of ORMF8 in type O used as the challenge virus when potency tests of porcine FMD vaccine was detected on pigs. The minimal infecting dose(MID) and the (median) infective dose(ID_(50)) were detected by three factories. The MID and ID_(50) determined by Lanzhou Veterinary (Research) Institute, Stock Lanzhou Biological Products Factory and Inner Mongolia Biological Products Factory of Jinyu Group were 10~(-6.0)/2 mL, 10~(-8.2)/2 mL; 10~(-7.0)/2 mL, 10~(-7.0)/2 mL; 10~(-6.0)/2 mL, 10~(-7.5)/2 mL respectively. The statistical results showed MID was 10~(-6.3)/2 mL and ID_(50) was 10~(-7.6)/2 mL. As a result, 1 MID was (equal) to 20 ID_(50) approximately in this test.

 用中国农科院兰州兽医研究所统一提供的猪口蹄疫O型灭活疫苗效检攻毒用种毒ORMF8,在3个企业同时用架子猪进行测毒,分别测得猪的最小感染量(MID)和猪的半数感染量(ID50)。3家单位测得的MID和ID50分别为10-6.0/2mL,10-8.2/2mL;10-7.0/2mL,10-7.0/2mL;10-6.0/2mL,10-7.5/2mL。将所有实验动物统计计算,MID约为10-6.3/2mL,ID50约为10-7.6/2mL。从这些数据得出,该试验1MID约为20ID50。

The PD_(50)(50% protective dose) potency of food and mouth disease(FMD) type O swine vaccine batch 0304041-2 was detected on pigs with different challenge viral dosage.The results showed that the potency was 5.2、(3.6)、2.1、1.0 PD_(50) per dose when using 500、1 000、2 000、4 000 ID_(50)which is the median infective dose as the challenge viral dosage, respectively. The results of virulence detection of FMD virus type O ORMF8 showed that the ID_(50) was 10~(-7.0) per 2 mL and the MID which is the minimal infecting...

The PD_(50)(50% protective dose) potency of food and mouth disease(FMD) type O swine vaccine batch 0304041-2 was detected on pigs with different challenge viral dosage.The results showed that the potency was 5.2、(3.6)、2.1、1.0 PD_(50) per dose when using 500、1 000、2 000、4 000 ID_(50)which is the median infective dose as the challenge viral dosage, respectively. The results of virulence detection of FMD virus type O ORMF8 showed that the ID_(50) was 10~(-7.0) per 2 mL and the MID which is the minimal infecting dose was 10~(-6.0) per 2 mL.

采用PD50 效检方法 ,对 0 30 4 0 4 1 2批猪口蹄疫O型灭活疫苗 (I型苗 )进行不同攻毒剂量的PD50 检测。结果表明 ,分别用 5 0 0ID50 、10 0 0ID50 、2 0 0 0ID50 和 4 0 0 0ID50 的病毒进行攻毒 ,疫苗每头份分别含 5 .2、3.6、2 .1和 1.0个PD50 。该项试验的攻毒毒株ORMF8的ID50 为 10 - 7.0 /2mL ,MID为10 - 6 .0 /2mL。

Objective To evaluate the effect and targeting ability of medical urea immunoliposomes conjugated with monoclonal antibody of vascular endothelial growth factor receptor2 (VEGFR2) on proliferation of hemangioma vascular endothelial cells ( HVEC) in vitro. Methods Many kinds of cytotox-icity experiment methods were used to observe the changes in morphology and growth curve of HVEC, and detect survival rate, killing ratio and doubling time of HVEC in vitro after HVEC were exposed to medical urea immunoliposomes....

Objective To evaluate the effect and targeting ability of medical urea immunoliposomes conjugated with monoclonal antibody of vascular endothelial growth factor receptor2 (VEGFR2) on proliferation of hemangioma vascular endothelial cells ( HVEC) in vitro. Methods Many kinds of cytotox-icity experiment methods were used to observe the changes in morphology and growth curve of HVEC, and detect survival rate, killing ratio and doubling time of HVEC in vitro after HVEC were exposed to medical urea immunoliposomes. Results The survival rate of HVEC showed a negative correlation with medical u-rea immunoliposomes final concentration. The median infective dose of medical urea immunoliposomes for HVEC was about 26 mg. The killing ratio of 2. 6% medical urea immunoliposomes for HVEC was about 99. 91% . After HVEC were exposed to 2. 6% medical urea immunoliposomes, the proliferation of HVEC was inhibited all the time and the growth curve exhibited obviously downward tendency all the time; The doubling time of HVEC was impossibly calculated according to formula. The medical urea immunoliposomes possessed persistently inhibitory action on proliferation of HVEC, and scarcely had the medical urea immunoliposomes acted upon HVEC when the medical urea immunoliposomes inhibited proliferation of HVEC. Conclusion The medical urea immunoliposomes inhibited the growth of HVEC in a dose-and time-dependent manner and had better action of targeting therapy for hemangioma.

目的探讨偶联血管内皮生长因子受体(VEGFR)2单克隆抗体的尿素免疫脂质体对血管瘤血管内皮细胞(HVEC)的增殖影响,对血管瘤是否有更好的靶向治疗作用。方法通过细胞毒性实验的多种方法,观察尿素免疫脂质体作用后HVEC的形态和生长曲线变化,检测HVEC细胞存活率、细胞杀伤率及细胞群体倍增时问。结果HVEC细胞存活率与尿素免疫脂质体终质量浓度呈显著负相关。尿素免疫脂质体对HVEC的半效应量(ID50)约26 mg。2.6%尿素免疫脂质体的细胞杀伤率为99.91%。2.6%尿素免疫脂质体作用HVEC后,HVEC的细胞增殖一直处于抑制状态,细胞群体倍增时间无法算出,生长曲线一直呈下降趋势,尿素免疫脂质体对HVEC的增殖抑制作用具有明显的持续效应,尿素免疫脂质体从接种药物开始就对HVEC的增值进行了抑制。结论尿素免疫脂质体对HVEC呈时间依赖性和剂量依赖性生长抑制作用,尿素免疫脂质体具有靶向治疗血管瘤的作用。

 
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