助手标题  
全文文献 工具书 数字 学术定义 翻译助手 学术趋势 更多
查询帮助
意见反馈
   endogenous toxin 的翻译结果: 查询用时:0.009秒
图标索引 在分类学科中查询
所有学科
更多类别查询

图标索引 历史查询
 

endogenous toxin
相关语句
  “endogenous toxin”译为未确定词的双语例句
     The Role of Dopamine as an Endogenous Toxin Triggered by Inhibition of VMAT in the Pathogenesis of the Parkinson Disease
     VMAT功能抑制触发的多巴胺内源性毒性在帕金森病发病机制中的作用
短句来源
     Conclusion: The endogenous toxin triggered by the inhibition of VMAT may carry on its effection through oxidative stress inducing apoptosis and necrosis.
     结论:VMAT功能抑制触发的多巴胺内源性毒性可能通过氧化应激诱发凋亡和坏死而发挥毒性作用。
短句来源
     The major pathogenesises of PD include oxidative stress,mitochondria malfunction, endogenous toxin and descent of neurotrophicfactor protection in the dopaminergic neurons.
     其主要的发病机制是氧化应激,线粒体功能不全,内源性毒素,神经营养因子保护作用下降,最终引起多巴胺神经元的变性和死亡。
短句来源
     In this study we tested the dopamine toxicity of various concentration to PC 12 cells and the synergism of the selective VMAT inhibitor - reserpine and detected the role of dopamine as an endogenous toxin triggered by inhibition of VMAT which might play a key role in the pathogenesis of PD and thus to illuminate an pathogenesis which could interpret the progressive and selective characteristic of PD more perfectively and rationally.
     本研究检测不同浓度多巴胺对大鼠嗜铬瘤细胞(PC12细胞)的毒性作用及加入VMAT特异性抑制剂利血平后的协同毒性作用,籍以探讨VMAT功能抑制触发的多巴胺内源性毒性在帕金森病发病机制中所起的作用,以阐明一个较为完善而合理地解释帕金森病特异性、进行性病理特点的发病机制。
短句来源
     Endogenous toxin affects directly pathological changes and prognosis in acute apoplexy and it is characterized by severe,scorching,attachment and usually invading viscera and bovels.
     内生毒邪直接影响着中风病急性期的病理变化、预后和转归,在中风病中具有毒性猛烈、毒性火热、依附性以及败坏形体、易攻脏腑等特点。
短句来源
更多       
  相似匹配句对
     On Formation,Development and Features of Endogenous Heat Toxin in Apoplexy
     中风病之内生热毒形成演变及特性初探
短句来源
     Preliminary Approach to the Endogenous Heat-toxin Theory of Apoplexy
     中风热毒论初探
短句来源
     2.toxin.
     2疫毒学说;
短句来源
     Phytopathogenic Toxin
     植物病原毒素
短句来源
     and the uncertainties are endogenous.
     以及不确定性来源的内生性等问题。
短句来源
查询“endogenous toxin”译词为用户自定义的双语例句

    我想查看译文中含有:的双语例句
例句
没有找到相关例句


Toxin is one of important concept in the etiology of traditional Chinese medicine.Extension and diversify are characteristics of toxin.Endogenous toxin affects directly pathological changes and prognosis in acute apoplexy and it is characterized by severe,scorching,attachment and usually invading viscera and bovels.Disturbance of ascending and descending of qi and blood is beginning factor of the occurrence of apoplexy.Blockage of phlem-blood is the core of pathogenesis and is pathological...

Toxin is one of important concept in the etiology of traditional Chinese medicine.Extension and diversify are characteristics of toxin.Endogenous toxin affects directly pathological changes and prognosis in acute apoplexy and it is characterized by severe,scorching,attachment and usually invading viscera and bovels.Disturbance of ascending and descending of qi and blood is beginning factor of the occurrence of apoplexy.Blockage of phlem-blood is the core of pathogenesis and is pathological basic of occurrence of toxin.Obstruction of bovels-qi is a pivot of the occurrence of toxin.Toxin damages the human body.Viscera and bovels,channels and collaterals.Blockage of phlem-blood exists throughout apoplexy.Detoxication and purgation are one of important therapeutic methods in acute apoplexy.

毒邪,是中医学重要的病因概念之一。毒邪致病具有广泛性和多样性的特点。内生毒邪直接影响着中风病急性期的病理变化、预后和转归,在中风病中具有毒性猛烈、毒性火热、依附性以及败坏形体、易攻脏腑等特点。气血逆乱,是中风病发病的始动因素。痰瘀交阻,是中风病病机的核心,并构成毒邪产生的病理基础;腑气不通是毒邪形成的枢纽;毒邪鸱张、败坏形体、损伤脏腑经络,变证丛生;脑络受损,痰瘀交阻贯穿始终。解毒通腑为中风病急性期的治疗大法

In order to understand the law of distribution of active thiol-group in Viscera the content of acfive thiol-group in Viscera were tested in a group of normal mice.Among six Viscera,which included liver,kidney,heart,lung,spleen and brain,the liver contained a level of active thiol-group of 450.29±73.38 mg/kg,and it was the highest one in these viscera tested.The order of the levels of thiol-group in these viscera was as following:liver>kidney (301.17±54.19 mg/kg)>spleen,heart and brain(267.43±47.33,263.29±48.23,and...

In order to understand the law of distribution of active thiol-group in Viscera the content of acfive thiol-group in Viscera were tested in a group of normal mice.Among six Viscera,which included liver,kidney,heart,lung,spleen and brain,the liver contained a level of active thiol-group of 450.29±73.38 mg/kg,and it was the highest one in these viscera tested.The order of the levels of thiol-group in these viscera was as following:liver>kidney (301.17±54.19 mg/kg)>spleen,heart and brain(267.43±47.33,263.29±48.23,and 254.11±49.87 mg/kg)>lung(226.74±46.28 mg/kg).The content of active thiol-group of each viscous in the group of 23~24 weeks old was higher that in the group of 5~6 weeks old and the group of 35~36 weeks old,respectively.No difference was found in both sexes.The results suggest that the high level of active thiol-group in liver may play an important role to detoxification for some exogenous of endogenous toxins.

为了解活性巯基在小白鼠脏器中分布规律 ,测定了一组正常小白鼠各脏器活性巯基含量。在包括肝、肾、心、脾、脑和肺在内的 6种脏器中 ,肝脏含活性巯基最高 ,为 450 .2 9± 73.38mg/kg,这些脏器活性巯基含量顺序依次为肝 >肾 (30 1 .1 7± 54.1 9mg/kg) >脾、心、脑 (分别为 2 67.43± 47.33、2 63.2 9± 48.2 3及 2 54.1 1± 49.87mg/kg) >肺 (2 2 6.74± 46.2 8mg/kg)。2 3~ 2 4周龄小白鼠各脏器活性巯基含量高于 5~ 6周龄及 35~ 36周龄组。动物性别间未发现巯基含量差异。结果提示肝脏高活性巯基含量在机体内源性或外源性毒素解毒中可能起到重要作用。

Objective:To study the apoptosis and necrosis mechani sm of dopamine neuron in Parkinson Disease. Methods:To observe the eff ect of VMAT inhibitors, reserpine, on apoptosis of PC12 cells with MTT and Flow Cytometer. Results:Reserpine itself has no cytotoxcity on P C12 c ells. Dopamine has cytotoxcity on CP12 cells when its concentration is over cert ain level (>0.03 mmol/L). Reserpine and dopamine combined to form synergic toxi city on PC12 cells. The apoptosis ratio of PC12 cells is obviously increased whe...

Objective:To study the apoptosis and necrosis mechani sm of dopamine neuron in Parkinson Disease. Methods:To observe the eff ect of VMAT inhibitors, reserpine, on apoptosis of PC12 cells with MTT and Flow Cytometer. Results:Reserpine itself has no cytotoxcity on P C12 c ells. Dopamine has cytotoxcity on CP12 cells when its concentration is over cert ain level (>0.03 mmol/L). Reserpine and dopamine combined to form synergic toxi city on PC12 cells. The apoptosis ratio of PC12 cells is obviously increased whe n these cells are induced by the same concentration of dopamine combind with res erpine and when these cells with lower concentration of dopamine (0.015 mmol/L) also decreased the Vito ratio. Conclusion:VMAT inhibitor makes dopamin e as an endogenous toxin, and induces the apoptosis of dopamine neurons.

目的:研究帕金森病黑质多巴胺神经元的死亡机理。方法:用四甲基偶氮唑盐(MTT)法及流式细胞仪观察囊泡单胺类转运(VMAT)功能抑制对大鼠嗜铬细胞瘤(PC12)细胞凋亡的影响。结果:单独作用的VMAT抑制剂利血平对PC12细胞无毒性作用;超过一定浓度的多巴胺(0.3mmol/L)对PC12细胞有毒性作用;利血平协同多巴胺明显增加多巴胺的毒性,使同样浓度的多巴胺诱发PC12细胞的凋亡率明显增加,致使较低浓度的多巴胺(0.15mmol/L)就可降低PC12细胞生存率。结论:VMAT功能抑制引发了多巴胺的内源性毒性,进而诱发多巴胺神经元的凋亡,可较好地解释帕金森病的发病机理。

 
<< 更多相关文摘    
图标索引 相关查询

 


 
CNKI小工具
在英文学术搜索中查有关endogenous toxin的内容
在知识搜索中查有关endogenous toxin的内容
在数字搜索中查有关endogenous toxin的内容
在概念知识元中查有关endogenous toxin的内容
在学术趋势中查有关endogenous toxin的内容
 
 

CNKI主页设CNKI翻译助手为主页 | 收藏CNKI翻译助手 | 广告服务 | 英文学术搜索
版权图标  2008 CNKI-中国知网
京ICP证040431号 互联网出版许可证 新出网证(京)字008号
北京市公安局海淀分局 备案号:110 1081725
版权图标 2008中国知网(cnki) 中国学术期刊(光盘版)电子杂志社