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viral capsid antigen
相关语句
  病毒壳抗原
     Significance of anti EB viral capsid antigen antibodies (VCA-IgM/IgG) for serodiagnosis of infectious mononucleosis
     抗EB病毒壳抗原抗体(VCA-IgM、IgG)测定对传染性单核细胞增多症诊断意义的探讨
短句来源
     Several monoclonal antibodies(McAbs) to Epstein—Barrvirus(EB) antigen—Viral capsid antigen (VGA), membrane antigen(MA), early antigen(EA), early antigen—diffuse (EA—D), early antigen—restricted (EA—R), EB unclear antigen (EBNA), EBNA—2 and latent membrane protein (LMP) were tested using a 3 steps amplified indirect immunoperoxidase method on 5 EB cell lines.
     5种EB病毒细胞系通过三步放大间接免疫过氧化物酶方法,检测抗EB病毒抗原的单克隆抗体(McAb)—病毒壳抗原(VCA)、膜抗原(MA),早期抗原(EA)、早期弥漫性抗原(EA—D)、早期限制性抗原(EA—R)、核抗原(EBNA)、核抗原第2型(EBNA—2)及潜在性膜蛋白(LMP)。
短句来源
     Purification and application of viral capsid antigen of Epstein Barr virus
     Epstein-Barr病毒壳抗原的纯化及其在检查血清抗体中的应用
短句来源
     The viral capsid antigen of Epstein Barr virus was purified from sf9 cells infected with recombinant Baculoviruses and the purified protein was used to establish ELISA and immunno strip method for detection of VCA/IgG and VCA/IgA antibodies in human sera.
     为了建立纯化Epstein-Barr(EB)病毒壳抗原(EBV-VCA)的方法,用于酶联免疫吸附试验(ELISA)检测人血清中的相关抗体,我们用重组昆虫病毒在感染的sf9细胞中表达EBV-VCA。 感染的细胞经裂解后,层析纯化表达产物。
短句来源
     INHIBITORY EFFECT OF SOME MEDICINES ON THE EXPRESSION OF VIRAL CAPSID ANTIGEN OF EPSTEIN-BARR VIRUS IN B95-8 CELLS
     几种药物抑制EB病毒壳抗原在体外细胞中表达的作用
短句来源
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  “viral capsid antigen”译为未确定词的双语例句
     Antibodies to EB Viral Capsid Antigen in Rhesus Monkey Sera
     恒河猴EB病毒有关抗体的检查
短句来源
     STUDY OF SERUM IgA ANTIBODY TO EB VIRAL CAPSID ANTIGEN IN NASOPHARYNGEAL CARCINOMA FROM SHAANXI
     陕西籍鼻咽癌患者血清EB病毒VCA—IgA抗体水平的研究
短句来源
     Relationship between p53 accumulation and immunoglobulin A against viral capsid antigen of Epstein-Barr virus(ⅠgA/VCA) in nasopharyngeal carcinoma(NPC)
     鼻咽癌组织p53蛋白积聚与血清EB病毒抗体ⅠgA/VCA的关系
短句来源
     OBSERVATION ON THE CHANGES OF SERUM IgA ANTIBODY TO EPSTEIN-BARR VIRAL CAPSID ANTIGEN IN ACUTE LEUKEMIA
     急性白血病EB病毒抗壳抗原抗体(VCA-IgA)变化的观察
短句来源
     Relationship between p53 and bcl 2 accumulation and immunoglobulin A against viral capsid antigen of Epstein Barr virus (IgA/VCA) in nasopharyngeal carcinoma(NPC)
     鼻咽癌组织p53、bcl2蛋白异常表达与血清EB病毒抗体IgAVCA滴度升高相关性研究
短句来源
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  相似匹配句对
     Study of Dengue Virus Capsid Targeted Viral Inactivation
     登革病毒衣壳蛋白靶向抗病毒作用的研究
短句来源
     Capsid-targeted viral inactivation for dengue virus infection
     衣壳蛋白靶向灭活策略应用于抗登革病毒感染的研究
短句来源
     Antibodies to EB Viral Capsid Antigen in Rhesus Monkey Sera
     恒河猴EB病毒有关抗体的检查
短句来源
     Purification and application of viral capsid antigen of Epstein Barr virus
     Epstein-Barr病毒壳抗原的纯化及其在检查血清抗体中的应用
短句来源
     STUDY OF SERUM IgA ANTIBODY TO EB VIRAL CAPSID ANTIGEN IN NASOPHARYNGEAL CARCINOMA FROM SHAANXI
     陕西籍鼻咽癌患者血清EB病毒VCA—IgA抗体水平的研究
短句来源
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  viral capsid antigen
IgG and IgA antibodies to viral capsid antigen (VCA), IgG antibodies to early antigen (EA), and antibodies to EBV nuclear antigen were detected at higher titers in sera of patients with uveitis than in the sera of healthy controls.
      
In the three groups of patients significantly higher titers of antibodies to EB viral capsid antigen (VCA) were found as compared to the controls.
      
Antibody levels against the viral capsid antigen of Epstein-Barr virus (EBV/VCA) in AHD patients were significantly higher, with overrepresentation of higher titres (≥1:160), than in matched controls.
      
The inhibitor reduced viral capsid antigen (VCA) positive cells.
      
High titers of antibodies to EBV, either IgG anti-viral capsid antigen or anti-early antigen, can be demonstrated.
      
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We have attempted to produce the P150 viral capsid antigen of Epstein-Barr Virus (EBV) in Escherichia coli. This protein was found, by immun-oprecipitation, to be a clinically relevant antigen, especially for the determination of the IgA-titer in patients with Naso Pharyngeal Carcinoma(NPC).Since the expression of the entire P150 coding region was unsuccessful, we synthesized only the antigenic parts of this protein. After purification of P150 expressed by PUR290CXH580 with column chromatography...

We have attempted to produce the P150 viral capsid antigen of Epstein-Barr Virus (EBV) in Escherichia coli. This protein was found, by immun-oprecipitation, to be a clinically relevant antigen, especially for the determination of the IgA-titer in patients with Naso Pharyngeal Carcinoma(NPC).Since the expression of the entire P150 coding region was unsuccessful, we synthesized only the antigenic parts of this protein. After purification of P150 expressed by PUR290CXH580 with column chromatography (sepharose 2B-CL), the resulting product reacts particularly well with IgA antibodies of NPC patients indicating its diagnostic value for NPC.

本文报告对EB病毒壳抗原(VCA)带有抗原决定簇的蛋白质在大肠杆菌中的表达及其纯化。以纯化后的蛋白为抗原检测人血清中VCA/IgA抗体,鼻咽癌病人及某些急性EB病毒感染人群呈抗体阳性.而对照组呈阴性。这一结果提示VCA蛋白在鼻咽癌的普查中有应用价值。

A total of 154 sera from patients with nasopharyngeal carcinoma(NPC), patients with other head and neck tumors(OHNT) and healthy individuals (HI) from Shaanxi province were tested for IgA antibody to EB viral capsid antigen (VCA-IgA) by immunoenzyrnie method. 75.93% of 54 pretreated NPC patients had VCA-IgA antibody with a GMT of 1: 38. 00,whereas less than 12. 00%of 50 OHNT and 50 HI with a GMT of 1: 2. 5 ~ 1: 3. 35.The results showed that the detection of VCA-IgA was of great value in diagnosis of NPC...

A total of 154 sera from patients with nasopharyngeal carcinoma(NPC), patients with other head and neck tumors(OHNT) and healthy individuals (HI) from Shaanxi province were tested for IgA antibody to EB viral capsid antigen (VCA-IgA) by immunoenzyrnie method. 75.93% of 54 pretreated NPC patients had VCA-IgA antibody with a GMT of 1: 38. 00,whereas less than 12. 00%of 50 OHNT and 50 HI with a GMT of 1: 2. 5 ~ 1: 3. 35.The results showed that the detection of VCA-IgA was of great value in diagnosis of NPC from low risk areas. The elevated level of VCA-IgA was seen in well-differentiated squamous cell carcinoma which gave a pattern similar to that noted in vacuolar nuclear cell carcinoma or less-differentiated carcinoma, but not in undifferentiated carcinoma. The VCA-IgA positive ratio in NPC patients below 30-year-old was similar to that in OHNT, however the GMT was elevated markedly. The results above showed that VCA-IgA antibody was of little value in diagnosis of NPC below 30-year-old and undifferentiated carcinoma.

用免疫酶法检测了陕西籍的鼻咽癌、头颈部其它肿瘤和健康人血清EB病毒VCA—IgA抗体。54例治疗前鼻咽癌其抗体阳性率为75.93%,几何平均滴度为38.00,而50例头颈部其它肿瘤和50例健康人的抗体阳性率低于12.00%,几何平均滴度为2.50~3.25。表明VCA—IgA测定对低发区鼻咽癌的临床诊断具有十分重要的参考价值。鼻咽高分化鳞癌同低分化鳞癌、泡状核细胞癌一样,血清VCA—IgA抗体的阳性率和几何平均滴度显著增高,而鼻咽未分化癌与头颈部其它肿瘤相似,显著低于上述3种病理类型。30岁以下鼻咽癌血清VCA—IgA抗体的阳性率与头颈部其它肿瘤相似,但几何平均滴度显著增高。以上结果表明,VCA—IgA检测对低发区鼻咽未分化癌和30岁以下鼻咽癌的诊断价值不大。

Several monoclonal antibodies(McAbs) to Epstein—Barrvirus(EB) antigenViral capsid antigen (VGA), membrane antigen(MA), early antigen(EA), early antigen—diffuse (EA—D), early antigen—restricted (EA—R), EB unclear antigen (EBNA), EBNA—2 and latent membrane protein (LMP) were tested using a 3 steps amplified indirect immunoperoxidase method on 5 EB cell lines. The results indicate a high specificity of McAbs, EBNA, EBNA—2 and EA. VCA and EA—R show specificity to a certain...

Several monoclonal antibodies(McAbs) to Epstein—Barrvirus(EB) antigenViral capsid antigen (VGA), membrane antigen(MA), early antigen(EA), early antigen—diffuse (EA—D), early antigen—restricted (EA—R), EB unclear antigen (EBNA), EBNA—2 and latent membrane protein (LMP) were tested using a 3 steps amplified indirect immunoperoxidase method on 5 EB cell lines. The results indicate a high specificity of McAbs, EBNA, EBNA—2 and EA. VCA and EA—R show specificity to a certain extent. MA, LMP and EA—D do not present expected specific reaction.

5种EB病毒细胞系通过三步放大间接免疫过氧化物酶方法,检测抗EB病毒抗原的单克隆抗体(McAb)—病毒壳抗原(VCA)、膜抗原(MA),早期抗原(EA)、早期弥漫性抗原(EA—D)、早期限制性抗原(EA—R)、核抗原(EBNA)、核抗原第2型(EBNA—2)及潜在性膜蛋白(LMP)。结果表明McAb、EBNA、EBNA—2和EA有较高特异性,VCA和EA—R有一定特异性,MA、LMP和EA—D未得到预期的特异性反应。

 
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