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plasma bicarbonate     
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  血浆碳酸氢盐
     RESULTS Plasma bicarbonate concentration and PCO 2 decreased from 20 74±2 81 mmol/L and 5 2 kPa to 11 26±3 22 mmol/L and 3 0 kPa respectively when the blood flowed through the dialyzer, while serum pH not evidently changed.
     结果:①经过透析器后,血浆碳酸氢盐浓度从2074±281mmol/L降至1126±322mmol/L,二氧化碳分压从52kPa降至30kPa,而血浆pH值无明显变化。
短句来源
     Evaluation of plasma bicarbonate SDS of short stature children can predict the probability of GHD,especially when bicarbonate SDS is less than 1 s.
     结论 :GHD儿童血浆 AB、碳酸氢盐SDS明显低于 ISS儿童 ,血浆碳酸氢盐 SDS≤ 1s者应高度怀疑 GHD。
短句来源
     Plasma bicarbonate concentration increased significantly after postdilution with bicarbonate solution which surpassed the loss of bicarbonate through dialyzer. Loss of bicarbonate from the blood to the dialysate obviously increased after plasma bicarbonate concentration reached at a normal level.
     ②随着透析时间的延长,血浆碳酸氢盐浓度明显增加,当血浆碳酸氢盐浓度达正常水平时,碳酸氢盐从透析器丢失明显增加。
短句来源
     Three infusion rates of bicarbonate (≥20 ml/min) can correct plasma bicarbonate concentration to normal range in 2 hours after the start of AFBF. No alkalosis were observed as AFBF continues for the self limitation mechanism.
     ③20ml/min、25ml/min和30ml/min三种不同的碳酸氢盐灌注速度,均能使患者在透析2h后血浆碳酸氢盐浓度达正常水平。
短句来源
  “plasma bicarbonate”译为未确定词的双语例句
     Methods:44 patients were enrolled in the study,their plasma bicarbonate concentration,pH value,blood urea nitrogen,serum creatinine,total protein,albumin,pre albumin,electrolyte,iPTH were measured,and eKT/V were calculated.
     方法:选择44例血透患者,采血测pH、HCO_3~-、BUN、Scr、总蛋白、ALB、前白蛋白、血常规、电解质、iPTH等并计算eKT/V。
短句来源
     Objective: To study the difference of plasma actual bicarbonate between the children with growth hormone deficiency(GHD) and idopathatic short stature(ISS) and to value the plasma bicarbonate standard deviation scores(SDS) in diagonosis of GHD.
     目的 :探讨生长激素缺乏 (GHD)和特发性矮身材 (ISS)儿童血浆实际碳酸氢盐浓度 (AB)差异 ,以及碳酸氢盐标准差评分 (SDS)在 GHD诊断中的价值。
短句来源
     A correlation was observed between the increase of QTd and the increase of plasma bicarbonate, ultrafiltration volume respectively (r=0.53,P<0.001;r=0.56,P<0.001, respectively).
     回归分析表明 ,透析后QTd增幅与透后HCO3 -的增高及透析脱水量呈正相关 (分别为r =0 .5 3 ,P <0 .0 0 1;r =0 .5 6,P <0 .0 0 1) ;
短句来源
     Results In MHD patients, QTd was higher than that in control. After the hemodialysis session, we found a significant increase (P<0.001) in QTd and a significant increase in plasma bicarbonate concentration (P<0.001).
     结果 :MHD患者透析前QTd明显高于正常对照组 (P <0 .0 0 1) ,透析后QTd进一步增高 (P <0 .0 0 1) ;
短句来源
     Methods Forty-four MHD patients were divided into 3 groups according to plasma bicarbonate concentrations (PHCO3) and pH values.
     方法按照患者透析前血浆碳酸氢根浓度(PHCO3)和动脉血pH值将病例分为3组,分析不同程度代谢性酸中毒以及酸中毒纠正情况对营养指标的影响。
短句来源
  相似匹配句对
     plasma;
     血浆游离DNA ;
短句来源
     Solitons in Plasma
     等离子体中的孤立子
短句来源
     Microencapsulation of Sodium Bicarbonate
     碳酸氢钠的微胶囊化
短句来源
     It is reported that sodium bicarbonate influence plasma concentrations of salicylate acid and its pharmacokinetic parameters when aspirin was given to rabbits by po.
     本文报告碳酸氢钠(SB)对家兔口服阿司匹林(ASP)后血浆水杨酸(SA)浓度及其药代动力学的影响。
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  plasma bicarbonate
The plasma bicarbonate, calcium, inorganic phosphate, potassium, sodium, globulin, creatinine and urea values were similar under both systems of management.
      
Significant increases in the values of Base Excess, plasma bicarbonate, standard bicarbonate and blood pH and a reduction in carbon dioxide tension indicated that the exercised animals were suffering from both respiratory and metabolic alkalosis.
      
Group 1 consisted of 52 patients with DKA (age: 41.9 ± 19.2 years; blood glucose (Glc): 27.4 ± 11.5 mmol/L; pH: 7.20 ± 0.16; plasma bicarbonate: 10.5 ± 6.2 mmol/L; blood urea nitrogen (BUN): 0.60 ± 0.44 g/L; HbA1C: 12.5% ± 2.8%).
      
True euglycaemic ketoacidosis (initial blood glucose 10 mmol/l or less) was rare, occurring in 0.8-1.1% of all episodes depending on the defining plasma bicarbonate concentration.
      
The original criteria described for euglycaemic ketoacidosis (initial blood glucose less than 16.7 mmol/l and plasma bicarbonate equal to or less than 10 mmol/l) were identified in 23 of 722 consecutive episodes (3.2%) of diabetic ketoacidosis.
      
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OBJECTIVE Acetate free biofiltration(AFBF) is a new technique in hemodiafiltration, in which a base free dialysate is applied and an isotonic bicarbonate solution infused in a postdilution mode. The hemodynamics of the bicarbonate in AFBF remained understudied. METHODOLOGY Sequential blood gas analysis and measurement of bicarbonate in dialysate were performed in 18 uremic patients during AFBF. RESULTS Plasma bicarbonate concentration and PCO 2 decreased from 20 74±2 81 mmol/L and 5 2 kPa to 11 ...

OBJECTIVE Acetate free biofiltration(AFBF) is a new technique in hemodiafiltration, in which a base free dialysate is applied and an isotonic bicarbonate solution infused in a postdilution mode. The hemodynamics of the bicarbonate in AFBF remained understudied. METHODOLOGY Sequential blood gas analysis and measurement of bicarbonate in dialysate were performed in 18 uremic patients during AFBF. RESULTS Plasma bicarbonate concentration and PCO 2 decreased from 20 74±2 81 mmol/L and 5 2 kPa to 11 26±3 22 mmol/L and 3 0 kPa respectively when the blood flowed through the dialyzer, while serum pH not evidently changed. Plasma bicarbonate concentration increased significantly after postdilution with bicarbonate solution which surpassed the loss of bicarbonate through dialyzer. Loss of bicarbonate from the blood to the dialysate obviously increased after plasma bicarbonate concentration reached at a normal level. Three infusion rates of bicarbonate (≥20 ml/min) can correct plasma bicarbonate concentration to normal range in 2 hours after the start of AFBF. No alkalosis were observed as AFBF continues for the self limitation mechanism. CONCLUSIONS Plasma bicarbonate concentration reaches a normal steady state at the third hour during AFBF, as the perfusion equals the loss of bicarbonate. Bicarbonate solution infusion rate at 25 ml/min was the best choice during AFBF.

目的:研究无醋酸盐生物滤过(AFBF)过程中碳酸氢盐血液动力学的变化。方法:对18例尿毒症患者在AFBF过程中进行血气分析动态观察并测定透出液中碳酸氢盐的含量。结果:①经过透析器后,血浆碳酸氢盐浓度从2074±281mmol/L降至1126±322mmol/L,二氧化碳分压从52kPa降至30kPa,而血浆pH值无明显变化。②随着透析时间的延长,血浆碳酸氢盐浓度明显增加,当血浆碳酸氢盐浓度达正常水平时,碳酸氢盐从透析器丢失明显增加。③20ml/min、25ml/min和30ml/min三种不同的碳酸氢盐灌注速度,均能使患者在透析2h后血浆碳酸氢盐浓度达正常水平。结论:碳酸氢盐的灌注速度决定了最终血浆碳酸氢盐浓度,但不会因补碱过多而造成碱中毒。

Objective To observe the effects of peritoneal dialysate containing pyruvate on peritoneal macrophages functions, electrolytes, metabolic acidosis and peritoneal mesothelium in uremic rats and compare with conventional lactate based solution. Methods The rats with stable chronic uremia were induced by two stages of 5/6 nephrectomy. After three months, all the animals received intraperitoneal injection of dialysis solution (25 ml/d) . After five weeks, the blood-gas analysis of artery was performed. The macrophages...

Objective To observe the effects of peritoneal dialysate containing pyruvate on peritoneal macrophages functions, electrolytes, metabolic acidosis and peritoneal mesothelium in uremic rats and compare with conventional lactate based solution. Methods The rats with stable chronic uremia were induced by two stages of 5/6 nephrectomy. After three months, all the animals received intraperitoneal injection of dialysis solution (25 ml/d) . After five weeks, the blood-gas analysis of artery was performed. The macrophages were separated from the peritoneal effluent for a dwell time of four hours. O2 the secretion of tumor necrosis factor-α (TNF-α) from the cells stimulated by LPS were investigated. Results The macrophages in the supernatant of pyruvate peritoneal effluent generated greater levels of 0: than that of lactate peritoneal effluent. The TNF-α secretion of macrophages from pyruvate peritoneal effluent increased significantly than that from lactate peritoneal effluent. Arterial plasma bicarbonate levels and pH of the rats received pyruvate dialysate were higher than those received lactate peritoneal solution. Light microscopy showed extensive mesothelial cell denudation, the surface was covered in some places with a thin layer of fibrin in rats received lactate peritoneal dialysate. Transmission electron microscopy revealed mesothelial cells microvilli missing. The rats received pyruvate peritoneal dialysate showed in part denudation of mesothelium. Transmission electron microscopy revealed the cells microvilli were sparse. Conclusions The peritonea] dialysate with pyruvate is more effective in correcting metabolic acidosis and preserving the peritoneal mesothelium. The cytotoxicity effect on macrophages can be lessened by using pyruvate anions.

目的 观察丙酮酸盐腹膜透析液对尿毒症大鼠代谢性酸中毒、电解质代谢、腹膜巨噬细胞功能及腹膜间皮的影响,并与乳酸盐腹膜透析液比较 方法 分两期对大鼠行 5/6肾切除,3个月后分别用丙酮酸盐腹膜透析液(PBPDF)。乳酸盐腹膜透析液(LBPDF)及含相同葡萄糖浓度的平衡盐水(GNS)进行腹腔内注射,4h后引流、分离透出液中的巨噬细胞进行孵育,测定用 LPS刺激后细胞超氧阴离子及肿瘤坏死因子。(TNF-α)的产量。首次透前及透析5周后做动脉血气分析及血清生化检查,并在光镜及电镜下观察腹膜间支形态。结果 透析5周后PBPDF组大鼠动脉血pH、HCO3浓度、腹膜巨噬细胞超氧阴离子及TNF-α的产量均高于LBPDF组,并且腹膜间皮损伤也较轻、而两组血清K-、Na+、Cl-水平差异无显著性意义。结论 丙酮酸盐腹膜透析液较乳酸盐腹膜透析液能更有效地纠正尿毒症大鼠的代谢性酸中毒,时腹膜巨噬细胞的抑制作用较轻,也能更好地维持腹膜间皮的完整性。

Objective: To study the difference of plasma actual bicarbonate between the children with growth hormone deficiency(GHD) and idopathatic short stature(ISS) and to value the plasma bicarbonate standard deviation scores(SDS) in diagonosis of GHD.Methods:Forty-seven short stature children were divided into two groups (GHD and ISS) according to the peak GH response to provocative test.Plasma actual bicarbonate concentrations anion gap (AG),base excess and electrolytes were measured in 47 children...

Objective: To study the difference of plasma actual bicarbonate between the children with growth hormone deficiency(GHD) and idopathatic short stature(ISS) and to value the plasma bicarbonate standard deviation scores(SDS) in diagonosis of GHD.Methods:Forty-seven short stature children were divided into two groups (GHD and ISS) according to the peak GH response to provocative test.Plasma actual bicarbonate concentrations anion gap (AG),base excess and electrolytes were measured in 47 children with short stature before GH provocative tests.Results:The mean plasma actual bicarbonate concentrations,bicarbonate SDS were (22.60±1.29)mmol/L and -0.27±0.98 respectively in GHD children,which were significantly lower than those of ISS children(P< 0.01),whereas AG was higher than that of ISS children [(11.73±4.52 vs 7.87±1.70) mmol/L],P<0.01. Seventy-two percent of patients with bicarbonate SDS≤1 s were dignosed as GHD.Conclusion:Plasma actual bicarbonate concentrations and bicarbonate SDS are lower in patients with GHD than those in patients with idopathatic short stature.Evaluation of plasma bicarbonate SDS of short stature children can predict the probability of GHD,especially when bicarbonate SDS is less than 1 s.

目的 :探讨生长激素缺乏 (GHD)和特发性矮身材 (ISS)儿童血浆实际碳酸氢盐浓度 (AB)差异 ,以及碳酸氢盐标准差评分 (SDS)在 GHD诊断中的价值。方法 :对 4 7例矮小症儿童作血气分析及电解质测定及 GH激发试验 ,根据 GH激发试验的峰值分为 GHD和 ISS两组 ,比较两组血浆 AB、碳酸氢盐 SDS、阴离子间隙 (AG)的差异。结果 :GHD儿童血浆 AB、碳酸氢盐 SDS分别为 (2 2 .6 0± 1.2 9) mmol/L、- 0 .2 7± 0 .98,明显低于 ISS组 [(2 3.80±0 .95 ) mmol/L、0 .6 4± 0 .73],P<0 .0 1;而 AG GHD组为 (11.73± 4 .5 2 ) mmol/L高于 ISS组 [(7.87± 1.70 ) mmol/L],P<0 .0 1。在碳酸氢盐 SDS≤ 1s的矮小儿童中 ,72 % (31/4 3)患儿为 GHD。结论 :GHD儿童血浆 AB、碳酸氢盐SDS明显低于 ISS儿童 ,血浆碳酸氢盐 SDS≤ 1s者应高度怀疑 GHD。

 
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