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interlobular bile ducts
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  小叶间胆管
     The main histopathological changes were: necroinflammation of interlobular bile ducts (100%, 27/27), lymphocyte aggregation or lymphocyte follicles (15%, 4/27), granuloma (26%, 7/27), decreased number of interlobular bile ducts and smaller bile duct proliferation (55%, 15/27), feathery degeneration of hepatocytes (59%, 16/27);
     肝组织病理学特点为:小叶间胆管变性坏死、基底膜不完整,周围有淋巴细胞和浆细胞浸润(66%,18/27); 汇管区淋巴细胞聚集(10%,27/27)或淋巴滤泡形成(15%,4/27);
短句来源
     Forty-six patients (93%) presented positive anti-mitochondrial antibody(AMA) or AMA-M2. The main histological changes were necroinflammation of interlobular bile ducts, lymphocyte aggregation or lymphocyte follicles, smaller bile duct proliferation, bilirubinostasis in canaliculi, but the typical histological change appeared only in 33% of bioptic patients.
     46例中有43例(93%)患者血清线粒体抗体或线粒体抗体M2亚型阳性。 主要的组织学变化为小叶间胆管变性、减少伴有淋巴细胞和浆细胞浸润、细小胆管增生、胆栓形成等,但出现典型组织学变化的阳性率仅有33%。
短句来源
     Conclusion:Ischemic injury in donor liver could be caused by warm and cold preservation,and injury of bile canaliculi and interlobular bile ducts might be the major cause of mild cholestasis in liver transplantation.
     结论:供肝毛细胆管和小叶间胆管上皮细胞的损伤是保存性损伤引起轻度胆汁淤积的主要因素。
短句来源
     The apoptosis of the epithelial cells may be related to the damage of interlobular bile ducts.
     而小叶间胆管周围小血管内皮细胞的损伤可能是导致小叶间胆管上皮细胞凋亡的直接原因。
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  “interlobular bile ducts”译为未确定词的双语例句
     (4) damage of interlobular bile ducts;
     (4)汇管区小叶间静脉内皮下炎细胞浸润 ;
短句来源
  相似匹配句对
     (4) damage of interlobular bile ducts;
     (4)汇管区小叶间静脉内皮下炎细胞浸润 ;
短句来源
     The apoptosis of the epithelial cells may be related to the damage of interlobular bile ducts.
     而小叶间胆管周围小血管内皮细胞的损伤可能是导致小叶间胆管上皮细胞凋亡的直接原因。
短句来源
     The Application of Fish Bile
     鱼类胆汁的应用
短句来源
     Apoptotic bodies and cellular debris were often noticed in the epithelial cells of bile canaliculi lumen and interlobular bile duct.
     部分小叶间胆管上皮细胞凋亡,管腔中含凋亡小体及细胞碎片。
短句来源
     Conclusions The appearances of mucinous epithelial metaplasias and numerous epithelial degenerations are the important signs of chronic inflammation of the interlobular bile ductulus.
     结论 :黏液上皮化生和上皮变性、坏死的增多是小叶间胆小管慢性炎症的重要标志。
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  interlobular bile ducts
Case Report: Terbinafine-Induced Prolonged Cholestasis with Reduction of Interlobular Bile Ducts
      
Features of primary biliary cirrhosis were pruritus, high titer of antimitochondrial antibodies, inflammatory infiltrates surrounding interlobular bile ducts, and periportal granuloma.
      
Each patient exhibited a paucity and hypoplasia of interlobular bile ducts, unusual facies, short stature, a pulmonary ejection systolic murmur, and structural anomalies of vertebrae.
      
Paucity of interlobular bile ducts getting to know it better
      
Fatty acid (FA) concentrations were studied in lymphocytes isolated from children with syndromic paucity of interlobular bile ducts (PILBD), Alagille syndrome.
      
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The livers from 5 week 14~32 human fetuses were studied. The results are summarized as follows:1. Two kinds of liver cells revealed by EM: the "light" and "dark" cells. The light ones are larger in size, more numerous in number, containing larger mitochondria and obvious RER and SER, but less free ribosomes than the dark ones. Both of them may contain hemosiderin granules and the configuration of mitochondria enclosed by circular or semicircular RER cisternae.2. Bile canaliculus: Beside canaliculi between...

The livers from 5 week 14~32 human fetuses were studied. The results are summarized as follows:1. Two kinds of liver cells revealed by EM: the "light" and "dark" cells. The light ones are larger in size, more numerous in number, containing larger mitochondria and obvious RER and SER, but less free ribosomes than the dark ones. Both of them may contain hemosiderin granules and the configuration of mitochondria enclosed by circular or semicircular RER cisternae.2. Bile canaliculus: Beside canaliculi between two adjacent liver cells, canaliculi situated between 3 or 4 liver cells are not infrequently revealed. That is due to the fetal liver cells are arranged in groups rather than in cords. The stereoscopic configurations of bile canaliculus and the tight junction surrounding it are demonstrated more clearly in freeze-fracture micrograph than that of the TEM. In addition, one intracellular bile canaliculus is found in the freeze-fracture preperation.3. The blood sinusoid and hemopoietic focus: In the 4-week fetus, the endothelium of the sinusoid can hardly be recognized While its lumen is quite large. Many erythrocytes accompanied by their immature components can be seen among it. As to the 32-week fetal liver, the endothelium and Kupffer cell may be easily recognized but the lumen of the sinusoid dimenishes enormously. The hemopoietic foci are localized extra-sinusoidially and in close contact with liver cells. Their volume exceeds one half of the fetal liver lobule before the age of 28 weeks, then it dimenishes gradually. In the space of Disse a fat storage cell is revealed.4. The portal canal : The mensenchyma and immature erythrocytes in the portal canal dimenishes with the increase of the fetal age. The portal canal is surrounded by the pigmented limiting plate cells of the liver lobules. The interlobular bile duct is differentiated from the limiting plate cells. Its epithelium is composed of both light and dark cells. The former is more numerous and contains many large mitochondria in its apical portion, while the latter shows higher electron density. Microvilli are located on the surfaces of both kinds of cells and finger like processes in the enlarged intercellular spaces are revealed.

本研究采用5例正常人14~32周水囊引产胎儿肝脏,进行了光镜、超薄切片和冷冻复型电镜的对比观察,发现并证实了: 1.肝细胞有明、暗之分, 2.肝细胞内有胆小管, 3.小叶间胆管由肝小叶的界板细胞形成,而构成管壁的上皮细胞也有明、暗之分。最后,根据观察所见并结合已有文献进行了分析讨论。

Liver specimens of 12 newborns are studied. In the newborn, adjucent lobules are not outlined precisely. The liver plates sepanated by hepatic sinusoids arpear as masses of cords in the section Hepatecytes are polyhedral cells that contain thin eosinephil granules,The clear and dark stained cells are obseived in 3 cases. There are scatters d hematopoietic focuses between the liver cord and hepatic sinusoid, or in hepatic sinusoids. There are one or two layers of periportal limiting plate cells around the portal...

Liver specimens of 12 newborns are studied. In the newborn, adjucent lobules are not outlined precisely. The liver plates sepanated by hepatic sinusoids arpear as masses of cords in the section Hepatecytes are polyhedral cells that contain thin eosinephil granules,The clear and dark stained cells are obseived in 3 cases. There are scatters d hematopoietic focuses between the liver cord and hepatic sinusoid, or in hepatic sinusoids. There are one or two layers of periportal limiting plate cells around the portal area. The interlobular bile ducts derived from the peripotal limiting plate are observed.

本文收集新生儿肝脏12例,用Bouin氏液固定,HE染色。镜下见肝小叶结构明显,相邻肝小叶分界不清,肝板在切面上呈团块状或条索状,与肝血窦交错排列,肝细胞呈多边形,胞质中有细小的嗜酸性颗粒,有3例围成团块状的肝细胞着色深浅不等。肝小叶内有散在的造血灶,门管周围有1~2层门管周围界板细胞。

Histochemical observasion and comparason have been made of biliary passage and gall bladder of normal dogs and gall stone dogs by HE and Alcian bluc-PAS and HTD-AB method.Results show that epithelial secretory functions of liver cells biliary passage,interlobular bile duet and mucosa of gall stone dogs become greater.The gall stone is formed by neutral and acid sulfoglycoproteion,which have been secreted from liver cells,biliary passage interlobular bile duct musosa and glands of gall stone...

Histochemical observasion and comparason have been made of biliary passage and gall bladder of normal dogs and gall stone dogs by HE and Alcian bluc-PAS and HTD-AB method.Results show that epithelial secretory functions of liver cells biliary passage,interlobular bile duet and mucosa of gall stone dogs become greater.The gall stone is formed by neutral and acid sulfoglycoproteion,which have been secreted from liver cells,biliary passage interlobular bile duct musosa and glands of gall stone dogs.

狗肝胆道系统组织化学及狗宝分泌形成初步研究¥实验动物中心(226001)邵义祥,朱顺星,毕书增,高长泽关键词狗宝;分泌与形成;肝胆道系统;狗狗宝是珍贵药材,是狗胆囊、膀胱等内脏器官的结石[1],自然形成的结石极少,在狗体内培植形成狗宝已有报道[2]....

 
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