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mannitol hexanitrate
相关语句
  六硝酸甘露醇
     Objective to study the hypotensive and antiasthmatic actions of mannitol hexanitrate (MH). Method The methods of tail artery and arteriae carotis communis intubation were used to detect the hypotensive action of MH on hereditary hypertension,and normal rats.
     采用大鼠颈总动脉插管法及尾动脉体表血压测量法对海洋药物六硝酸甘露醇(mannitol hexani-trate,MH)进行了急性及慢性降压实验,观察了MH对遗传性高血压大鼠及正常大鼠的降压作用。
短句来源
  “mannitol hexanitrate”译为未确定词的双语例句
     STUDIES ON HYPOTENSIVE AND ANTIASTHMATIC ACTIONS OF MANNITOL HEXANITRATE IN RATS AND GUINEA PIGS
     海洋药物六硝酸甘露醇的降压及平喘作用
短句来源
  相似匹配句对
     A STUDY OF DETERMINATION METHOD OF D-MANNITOL HEXANITRATE
     六硝酸甘露醇酯的含量测定方法研究
短句来源
     F10 (D-mannitol).
     F10:D-甘露醇。
短句来源
     D-mannitol (15) .
     D-mannitol,D-甘露醇(15)。
短句来源
     STUDIES ON HYPOTENSIVE AND ANTIASTHMATIC ACTIONS OF MANNITOL HEXANITRATE IN RATS AND GUINEA PIGS
     海洋药物六硝酸甘露醇的降压及平喘作用
短句来源
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Objective to study the hypotensive and antiasthmatic actions of mannitol hexanitrate (MH). Method The methods of tail artery and arteriae carotis communis intubation were used to detect the hypotensive action of MH on hereditary hypertension,and normal rats. The preventive effect of MH was observed in experimental bronchial asthma caused by histamine and acetylcholine. Result After MH was taken by po for thirty days in succession, MH has shown a hypotensive action on hereditary hypertensive rats. Blood...

Objective to study the hypotensive and antiasthmatic actions of mannitol hexanitrate (MH). Method The methods of tail artery and arteriae carotis communis intubation were used to detect the hypotensive action of MH on hereditary hypertension,and normal rats. The preventive effect of MH was observed in experimental bronchial asthma caused by histamine and acetylcholine. Result After MH was taken by po for thirty days in succession, MH has shown a hypotensive action on hereditary hypertensive rats. Blood pressure of rats was reduced by 26 + 8mmHg. Taking the medicine per oral (80mg/kg) and duodenal (40,80mg/kg) ,MH had not an obvious effect on blood pressure of normal rats in the methods of tail arteries and arteriae carotis communis intubation. The asthmatic incubation period was prolonged for 33?0s by MH (80mg/kg) in the experimental bronchial asthma. Conclusion The results of the study suggest that MH produces a mild hypotensive action on hereditary hypertensive rats and a preventive effect on bronchial asthma.

采用大鼠颈总动脉插管法及尾动脉体表血压测量法对海洋药物六硝酸甘露醇(mannitol hexani-trate,MH)进行了急性及慢性降压实验,观察了MH对遗传性高血压大鼠及正常大鼠的降压作用。MH[80mg/(kg.d)]经ig连续用药30d后,使遗传性高血压大鼠的血压由用药前的198±12mmHg降至172±6mmHg,平均降低了26±8mmHg,与NS对照组比较差异显著(P<0.05)。同样剂量的MH经ig30d后,使正常大鼠的尾动脉血压平均降低12±7mmHg(P>0.05)。在急性降压实验中,采用颈动脉插管法,MH[80、40/kg.d)]经十二指肠内给药,使正常大鼠的颈总动脉血压降低了14±6mmHg,与NS组比较,差异不显著(P>0.05)。在由乙酰胆碱和组胺诱发的支气管哮喘的模型中,预先igMH(80mg/kg),每日两次,连续用药1w,可使豚鼠的引喘潜伏期延长33±10s,与NS组比较差异显著(P<0.05)。实验结果表明,MH对遗传性高血压大鼠有较温和的降压作用,并对实验性支气管哮喘有一定的预防作用。

A simple determination method of D-mannitol hexanitrate used by coronary vasodilator and its characteristics were studied. The spectrophotometric method was based on the developing colour system of D-mannitol hexanitrate and phenol disulfonic acid. The results show that the method is simple, sensitive and constant. The standard deviation is 0. 74, and the relative standard deviation is 0. 80 % for containing 93. 0 % D-mannitol hexanitrate (n=9). The method is fit as a standard method for monitoring...

A simple determination method of D-mannitol hexanitrate used by coronary vasodilator and its characteristics were studied. The spectrophotometric method was based on the developing colour system of D-mannitol hexanitrate and phenol disulfonic acid. The results show that the method is simple, sensitive and constant. The standard deviation is 0. 74, and the relative standard deviation is 0. 80 % for containing 93. 0 % D-mannitol hexanitrate (n=9). The method is fit as a standard method for monitoring production process of pharmacopoeia.

对冠状血管扩张药──六硝酸甘露醇酯的性质及其含量测定方法进行了讨论,采用六甘酯-苯酚二磺酸显色体系进行分光光度法测定。结果表明,本法操作简单,显色稳定 灵敏,对含六甘酯93.0%的样品测定9次其标准偏差为0.74,相对标准偏差0.80%,适用于 生产质量检测和建立药典规范方法。

 
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