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reversible decrease
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  “reversible decrease”译为未确定词的双语例句
     The in vitro 1H MRS of hippocampus revealed the reversible decrease of NAA/Cr, which had negative correlation with TAOC(Pearson correlation coefficient was-0.624, P value was 0.003) and positive correlation with Cho/Cr level(Pearson correlation coefficient was 0.556, P value was 0.011).
     与对照组相比,实验组海马NAA蛐Cr表现为先降低后升高,这种变化与病理生理学检测的总抗氧化能力(TAOC)具有负相关性(Pearson相关系数为-0.624,P值为0.003),与1HMRS检测的Cho蛐Cr的变化具有正相关性(Pearson相关系数为0.556,P值为0.011)。
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     2-iodomelatonin, an agonist of melatonin receptor, could cause a reversible decrease the IA current amplitude in all tested cells, and modified the IA channel activation kinetics of control cells.
     2-iodomelatonin,一种褪黑素受体激动剂,能可逆性的抑制小脑颗粒细胞的I_A电流,同时改变了正常细胞I_A电流的稳态激活特性;
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     50ug terbinafine caused mild inflammatory response in the vitreous without retinal histological changes , while the concentration caused a reversible decrease in the ERG b-wave.
     特比萘芬50ug/0.1ml引起眼内轻微炎症反应,视网膜组织结构未见明显异常,但ERG显示有可逆性降低;
短句来源
     Result:The effective rate of pain relief was 90%(28/31), the PSA level reduced, and the main side effect were the mild reversible decrease of white blood cells, hemoglobin and platelets.
     结果 :89Sr治疗止痛总有效率为 90 .3% (2 8/ 31) ,PSA均有下降 ; 不良反应主要为轻度可逆性骨髓造血功能损害 ;
短句来源
     30 IU Hyaluronidase and 2 IU Plasmin both caused mild inflammatory response in the vitreous without retinal histological changes, while the latter caused a reversible decrease in the ERG b-wave.
     注药后进行裂隙灯、+90 D前置镜、间接检眼镜、视网膜电流图(ERG)、B超及相干光断层扫描检查,观察2周后,眼球组织标本做光镜及扫描电镜观察。
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  相似匹配句对
     Decrease in Calories
     减少热量
短句来源
     Reversible Renascence
     可逆转性的重生
短句来源
     Immunologic function decrease.
     免疫结构退化与功能下降。
短句来源
     This procedure is reversible.
     这种变化是可逆的。
短句来源
     The results showed that the presence of H 2O resulted in a decrease in the NO reduction activity and the inhibition effect was reversible.
     结果表明 ,Ag Al2 O3 的还原NO活性优于其它催化剂 .
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  reversible decrease
Deoxycholate at 0.05% induced a reversible decrease of TEER; a 2- and 50-fold enhancement on the transepithelial transport of 14C-sucrose and HRP, respectively, was observed.
      
Determination of high energy phosphates showed that 24 h TNFα-exposure resulted in a reversible decrease of ATP, ADP, AMP and CP by 30-40% (p >amp;lt; 0.05).
      
A rise in hexose concentrations, above a threshold value in excess of 5.6 mM, caused a rapid, sustained and rapidly reversible decrease in the mitochondrial NADH/NAD+ ratio.
      
In particular it was found that NiO, Co3O4 and Mn3O4 thin films showed reversible decrease in the Vis-NIR absorption due to CO.
      
The phenomenon, which involves the reversible increase of the tension surface electrical resistance and the reversible decrease of the compression surface electrical resistance upon flexure, allows strain sensing.
      
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Objective: To study the effect of satragaloside Ⅳ on the microvascular permeability induced by histamine in pial microvessels. Method: The microvascular permeability was expressed by changes in the transendothelial electrical resistance which was measured with technique using microelectrode impaled into the vascular lumen and based on cable analysis of vessels in rat. Result: The transendothelial electrical resistance of microvessels superfused with artificial cerebrospinal fluid was about 2500 Ω·cm 2, indicating...

Objective: To study the effect of satragaloside Ⅳ on the microvascular permeability induced by histamine in pial microvessels. Method: The microvascular permeability was expressed by changes in the transendothelial electrical resistance which was measured with technique using microelectrode impaled into the vascular lumen and based on cable analysis of vessels in rat. Result: The transendothelial electrical resistance of microvessels superfused with artificial cerebrospinal fluid was about 2500 Ω·cm 2, indicating a tight barrier with extremely low ion permeability, and application of 10 -4 mol·L -1 histamine in superfusate caused a rapid and reversible decrease in transendothelial electrical resistance. In paired experiment, the decrease of transendothelial electrical resistance induced by 10 -4 mol·L -1 histamine was inhibited by adding 0.8×10 -4 mol·L -1 satragaloside Ⅳ in superfusate. Conclusion: The results indicated that increases in the microvascular permeability induced by histamine, and satragaloside Ⅳ can inhibit the increases in the microvascular permeability induced by histamine. It is necessary that the cellular mechanism of permeability response induced by satragaloside Ⅳ be further elucidated.

目的 :观察黄芪皂苷甲对组胺引起的脑软膜微血管通透性增加的抑制作用。方法 :脑软膜微血管通透性用跨脑软膜微血管内皮的电阻表示 ,跨脑软膜微血管内皮的电阻通过将微电极插入微血管腔内记录 ,并用电缆公式计算获得。结果 :脑软膜微血管经灌流人工脑脊液 ,测得的跨内皮电阻大约为 2 5 0 0Ω·cm2 ,说明微血管内皮是具有较低通透性的致密屏障 ,在人工脑脊液中加入 10 -4 mol·L-1组胺引起跨内皮电阻快速的和可逆性的下降。在配对实验中 ,10 -4 mol·L-1组胺引起跨内皮电阻的下降能够被在人工脑脊液中加入 0 .8× 10 -4 mol·L-1黄芪皂苷甲所抑制。结论 :实验结果表明组胺能够引起脑微血管通透性增加 ,而黄芪皂苷甲能够抑制组胺引起脑微血管通透性增加。有关黄芪皂苷甲引起通透性反应的细胞机制需进一步研究。

OBJECTIVE:To study the effect of ferulic acid sodium on the increase of the pial microvascular permeability induced by histamine METHODS: The microvascular permeability was expressed by changes in the transendothelial electrical resistance which was measured with technique using microelectrode impaled into the vascular lumen and based on cable analysis of vessels in rat RESULTS:The transendothelial electrical resistance of microvessels superfused with artificial cerebrospinal fluid was about 2 500 Ω·cm ...

OBJECTIVE:To study the effect of ferulic acid sodium on the increase of the pial microvascular permeability induced by histamine METHODS: The microvascular permeability was expressed by changes in the transendothelial electrical resistance which was measured with technique using microelectrode impaled into the vascular lumen and based on cable analysis of vessels in rat RESULTS:The transendothelial electrical resistance of microvessels superfused with artificial cerebrospinal fluid was about 2 500 Ω·cm 2 , indicating a tight barrier with extremely low ion permeability, and application of 10 4 mol·L 1 histamine in superfusate caused a rapid and reversible decrease of resistance In paired experiment, 10 4 mol·L 1 histamine induced decrease of transendothelial electrical resistance was inhibited by adding 10 5 mol·L 1 ferulic acid sodium in superfusate CONCLUSION:The results indicated that increases in the microvascular permeability can be induced by histamine, and ferulic acid sodium can inhibit the increases in the microvascular permeability induced by histamine It is necessary that the cellular mechanism of permeability response induced by ferulic acid sodium remains to be further elucidated

目的 :观察阿魏酸钠对组胺引起的脑软膜微血管通透性增加的抑制作用。方法 :脑软膜微血管通透性用跨脑软膜微血管内皮的电阻表示 ,跨脑软膜微血管内皮的电阻通过将微电极插入微血管腔内记录 ,并用电缆公式计算获得。结果 :脑软膜微血管经灌流人工脑脊液 ,测得的跨内皮电阻大约为 2 5 0 0Ω·cm2 ,说明微血管内皮是具有较低通透性的致密屏障 ,在人工脑脊液中加入 10 4 mol·L 1组胺引起跨内皮电阻快速的和可逆性的下降。在配对实验中 ,10 4 mol·L 1组胺引起跨内皮电阻的下降能够被在人工脑脊液中加入 10 5mol·L 1阿魏酸钠所抑制。结论 :结果表明组胺能够引起脑微血管通透性增加 ,而阿魏酸钠能够抑制组胺引起脑微血管通透性增加

This study was designed to compare the effects of protease-activated receptor 1 (PAR-1) and protease-activated receptor 4 (PAR -4) to the expression of platelet surface GPIbα and cytoskeleton reorganization, then to investigate the role of P ARs in platelet signal transmission. PAR1 (25 μmol/L) and PAR4 (250 μmol/L) we re used to stimulate platelet at different time points (0-60 minutes), and the p latelet surface GPIbα, actin and myosin and P-selectin were detected with flow cytometry, the alteration...

This study was designed to compare the effects of protease-activated receptor 1 (PAR-1) and protease-activated receptor 4 (PAR -4) to the expression of platelet surface GPIbα and cytoskeleton reorganization, then to investigate the role of P ARs in platelet signal transmission. PAR1 (25 μmol/L) and PAR4 (250 μmol/L) we re used to stimulate platelet at different time points (0-60 minutes), and the p latelet surface GPIbα, actin and myosin and P-selectin were detected with flow cytometry, the alteration of GPIbα, actin and myosin in cytoskeleton was compared by Western blot, the membrane cytoskeleton followed GPIbα immunop recipitation was analyzed. The results showed that an increase of P-selectin an d reversible decrease of GPIbα expression were obtained after platelet activation by PAR1 o r PAR4, and a different kinetics of redistribution of GPIbα was found for the t wo peptides all over the time course (P<0 05). PAR1 acted more potently and rapidly than PAR4, but the effect of PAR4 persisted longer in the course of plat elet activation. Meanwhile, there was a transient change of actin, myosin and GP Ibα in cytoskeleton proteins. Similar redistribution was also found in GPIbα/m yosin and GPIbα/actin association. It is concluded that PAR1 and PAR4 possess a n important role in platelet signal transmission. Either of the receptors can me diate platelet activation and GPIbα redistribution, which is correlated with cy toskeleton reorganization. PAR1 acts more rapidly, and effect of PAR4 persists l onger.

为了比较蛋白酶活化受体 1和 4(PAR1,PAR4)合成肽对血小板膜表面糖蛋白GPIbα表达及细胞骨架的影响 ,揭示蛋白酶活化受体在血小板信号传递中的作用 ,选择 2 5μmol/LPAR1与 2 50 μmol/LPAR4两类合成肽分别在不同时间段 (0 -60分钟 )活化血小板 ,应用流式细胞仪测定血小板膜糖蛋白GPIbα及P 选择蛋白的表达 ,并结合SDS PAGE与转移电泳技术比较血小板活化前后细胞骨架GPIbα、肌动蛋白、肌球蛋白的变化 ,同时对膜骨架成分进行GPIbα免疫沉淀分析。结果显示 ,PAR 1与PAR4两类合成肽均可促使血小板活化 ,其P 选择蛋白水平显著升高 ,GPIbα表达进行性减少又出现逐渐回升的可逆性变化 ,各时间段引起的GPIbα改变在两者之间都具有显著差异 (P <0 .0 5) ,其中PAR1首先发生作用 ,但PAR4维持时间更长。细胞骨架蛋白分析显示肌动蛋白与肌球蛋白协同GPIbα呈现先增加后减少的动态变化。免疫印迹也表明与GPIbα相连的肌动蛋白及肌球蛋白出现可逆性改变。结论 :PAR1与PAR4在血小板信号传递过程中发挥了重要作用 ,它们能各自独立地介导血小板活化 ...

为了比较蛋白酶活化受体 1和 4(PAR1,PAR4)合成肽对血小板膜表面糖蛋白GPIbα表达及细胞骨架的影响 ,揭示蛋白酶活化受体在血小板信号传递中的作用 ,选择 2 5μmol/LPAR1与 2 50 μmol/LPAR4两类合成肽分别在不同时间段 (0 -60分钟 )活化血小板 ,应用流式细胞仪测定血小板膜糖蛋白GPIbα及P 选择蛋白的表达 ,并结合SDS PAGE与转移电泳技术比较血小板活化前后细胞骨架GPIbα、肌动蛋白、肌球蛋白的变化 ,同时对膜骨架成分进行GPIbα免疫沉淀分析。结果显示 ,PAR 1与PAR4两类合成肽均可促使血小板活化 ,其P 选择蛋白水平显著升高 ,GPIbα表达进行性减少又出现逐渐回升的可逆性变化 ,各时间段引起的GPIbα改变在两者之间都具有显著差异 (P <0 .0 5) ,其中PAR1首先发生作用 ,但PAR4维持时间更长。细胞骨架蛋白分析显示肌动蛋白与肌球蛋白协同GPIbα呈现先增加后减少的动态变化。免疫印迹也表明与GPIbα相连的肌动蛋白及肌球蛋白出现可逆性改变。结论 :PAR1与PAR4在血小板信号传递过程中发挥了重要作用 ,它们能各自独立地介导血小板活化 ,并导致GPIbα逆转 ,这与细胞骨架的积极参与相关。PAR1起效较快 ,PAR4维持作用更长久

 
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