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病毒性肝炎患者
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  patients with viral hepatitis
    Methods: Bifendate, 7.5 mg tid, was taken for 28 days in 64 patients with viral hepatitis who had the abnormal ALT and no jaundice, and their liver function changes were observed.
    方法:选择我院血清ALT异常的无黄疸型病毒性肝炎患者,共64例。 服用联苯双酯7.5mg tid治疗28天,观察其对肝功能的影响。
短句来源
    Methods A total of 98 patients with viral hepatitis were divided into four groups.
    方法  98例病毒性肝炎患者分成 4组 ;
短句来源
  “病毒性肝炎患者”译为未确定词的双语例句
    THE CLINICAL SIGNIFICANCE OF PLASMA AMINO ACID ALTERATIONS IN PATIENTS WITH ACUTE VIRAL HEPATITIS
    急性病毒性肝炎患者血浆氨基酸改变的临床意义
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  patients with viral hepatitis
The absence of specific presentation of acute urticaria in, patients with viral hepatitis is not surprising because many other viral infections can induced similar cutaneous symptoms.
      
In patients with viral hepatitis (n=21) during the acute phase all four fractions of plasma glycosphingolipids were elevated compared to healthy subjects (n=23).
      
Medication costs for acute liver failure were higher, due to a high administration rate of expensive anti-HBs immunoglobulin therapy in patients with viral hepatitis B.
      
The cyclobarbital (CB) half-life was prolonged and the clearance reduced in patients with viral hepatitis, cirrhosis, or alcoholic liver damage as compared to data from 17 control subjects.
      
The different forms of acidophilic alterations of single liver cells (acidophilic degeneration, acidophilic necrosis, and Councilman-like bodies) in liver tissue of patients with viral hepatitis were studied by light and electron microscopy.
      
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Nine healthy volunteers received a single dose of 7.5mg/kg of Amikacin intramuscularly, Amikacin was rapidly absorbed from injection site. A peak serum level after 1 hr averaged 23.59/μg/nl, and declined to 12.77μg/ml 3 hrs later. 12 hrs after the administration of Amikacin in serum was 0.78/μg/ml. Pharmacokinetical parameters of Amikacin were determined by a least-squares. Analysed parameters were based on a two-compartment, open-system kinetic model. The halflife time of Amikacin was 2.48 hrs. Apparent volumes...

Nine healthy volunteers received a single dose of 7.5mg/kg of Amikacin intramuscularly, Amikacin was rapidly absorbed from injection site. A peak serum level after 1 hr averaged 23.59/μg/nl, and declined to 12.77μg/ml 3 hrs later. 12 hrs after the administration of Amikacin in serum was 0.78/μg/ml. Pharmacokinetical parameters of Amikacin were determined by a least-squares. Analysed parameters were based on a two-compartment, open-system kinetic model. The halflife time of Amikacin was 2.48 hrs. Apparent volumes of distribution averaged 22.6% of body weight, and the mean rate of renal clearance was 72.56ml/min. Of the administered dose, 92.28% was recovered from the urine in 24 hours.

九名健康人单次肌注丁胺卡那霉素7.5mg/kg,1小时后的高峰血浓度为23.58μg/ml,3小时的血清浓度为高峰血浓度的1/2(12.77μg/ml),12小时浓度降至0.78/μg/ml。药物主要从肾脏排出,24小时内排出给药量的92.28%,100μg/ml以上的尿浓度可维持12小时,最高可达1451μg/ml。血清浓度动力学按两室开放式模型分析,表观分布容积Vd13.56升,肾清除率Q72.56ml/min。根据动力学参数计算出的不同时间的血浓度与实测值非常接近。五名病毒性肝炎患者肌注相同剂量的丁胺卡那霉素后,血浓度与正常人的水平相接近。1例老年慢性病毒性肝炎肝硬变病人,肌注丁胺卡那霉崇7.5mg/kg后,血浓度明显高于正常人,血清消除半衰期为6.3小时,提示该类病人体内动力学过程有所改变。

. R.China Six

用聚合酶链反应(PCR)方法动态观来了α-干扰素治疗的6例慢性乙型病毒性肝炎患者外周血单个核细胞(PBMC)与血清中乙型肝炎病毒(HBV)DNA的清除情况。血清HBVDNA在治疗5周后(3-10周)6例转阴,其中2例在结束治疗时复转阳性,PBMC中HBVDNA在治疗15周(12-20周)时5例转阴,1例始终阳性,并出现ALT复升高。结果显示α-干扰素能清除PBMC中HBVDNA,但滞后于血清病毒的清除,PBMC中HBVDNA持续阳性,可能使治疗中期效果较差。

Twenty patients with hepatitis C were treated with interferon

对20例丙型病毒性肝炎患者用重组α-2b干扰素治疗,观察其近、远期疗效,发现干扰素对丙型病毒性肝炎有效。治疗3个月(一疗程)后,60%的患者丙型肝炎病毒(HCV)RNA转阴,88.9%的患者肝功能恢复正常,但停药后其中部分患者HCVRNA又出现阳性,肝功能出现反复。随访1~2a,发现肝功能稳定正常者占52.6%,HCVRNA持续阴转者占31.6%。用干扰素治疗的丙型肝炎患者,凡早出现临床症状者,预后佳;HCVRNA持续阴转者,不易复发,病情稳定。

 
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