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   oral inoculation 在 基础医学 分类中 的翻译结果: 查询用时:0.636秒
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oral inoculation    
相关语句
  口服接种
    Objective To investigate the effects on the immune response of mice with rBCG vaccination expressing foreign antigen Der p2 in the form of lipoprotein by oral inoculation.
    目的观察胞壁型重组BCG(rBCG)经口服接种后对BALB/c小鼠TH细胞免疫应答的影响。
短句来源
  口服免疫
    Oral inoculation of recombinant BCG expressing Der p2 in the form of lipoprotein induces antigen-specific TH1 predominant immune response in mice
    胞壁型rBCG经口服免疫可以诱导BALB/c小鼠产生抗原特异性T_H1应答
短句来源
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  oral inoculation
These data are important because they indicate that the antigenic load achieved following a single oral inoculation is sufficient to achieve long lasting immunity, the goal of any potential vaccine.
      
Pups born to dams immunized by oral inoculation with live MHV acquired both MHV-specific IgA and IgG in their whey, while pups born to dams immunized with killed virus acquired only IgG.
      
The in vivo dose study (1, 10, 25, 50 μg of OVA) was performed by subcutaneous and oral inoculation in mice by single (0 week) or double (0 and 3 weeks) administration of PLGA 50/50 microspheres containing 0.1% OVA.
      
Oral inoculation of strains lacking the 55 kb plasmid did not cause any mortality.
      
In order to determine if intra-oral inoculation could explain the pathogenesis of paracoccidioidomycosis, 64 BALB/c mice were inoculated intra-orally with 850.000 viable P.
      
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C. jacchus and S. mystax were inoculated intravenously and orally with hepatitis A virus respectively, followed by needle biopsy of liver at regular intervals. It revealed that after the infection, the pathological lesions of hepatitis and progress of the pathological changes were found both under light and electron microscopes, associated with elevation of serum GPT and GOT, appearance of antibody and shedding of the virus in the feces. These findings suggest that both C. jacchus and S. mystax can be the animal...

C. jacchus and S. mystax were inoculated intravenously and orally with hepatitis A virus respectively, followed by needle biopsy of liver at regular intervals. It revealed that after the infection, the pathological lesions of hepatitis and progress of the pathological changes were found both under light and electron microscopes, associated with elevation of serum GPT and GOT, appearance of antibody and shedding of the virus in the feces. These findings suggest that both C. jacchus and S. mystax can be the animal models of human hepatitis A by intravenous or oral inoculation with hepatitis A virus.

本文系将人甲型肝炎(下称甲肝)病毒经胃肠遭感染白髭狨猴和静脉感染普通狨猴后,定期进行肝穿活检,从组织病理学变化,结合转氨酶及抗体的改变、大便排病毒阳性,评估肝穿活检对确诊狨猴实验性甲肝模型的价值。感染动物在光镜和电镜下肝组织均呈现肝炎病变,提示经两种不同途径给两种狨猴感染甲肝病毒,都可能成为甲肝病毒实验的动物模型。

Cyst suspension(6000 cyst/ml)of Giardia lamblia obtained and purified from a 62—years—old farmerliving in a rural area of Sichuan province was used to infect the suckling gerbils Meriones unguiculatus.Onday 7 after oral inoculation,trophozoites isolated aseptically from the upper intestinal tract of the infectedanimals were inoculated into modified TYI—S—33 medium and cultivated at 37℃.On day 4 of the culti-vation,the organisms became adapted to the in vitro cultivation,so that they formed a cellular monolayer...

Cyst suspension(6000 cyst/ml)of Giardia lamblia obtained and purified from a 62—years—old farmerliving in a rural area of Sichuan province was used to infect the suckling gerbils Meriones unguiculatus.Onday 7 after oral inoculation,trophozoites isolated aseptically from the upper intestinal tract of the infectedanimals were inoculated into modified TYI—S—33 medium and cultivated at 37℃.On day 4 of the culti-vation,the organisms became adapted to the in vitro cultivation,so that they formed a cellular monolayer onthe inner surface of the culture tube.No bacterial or fungal growth was detected by plating aliquots of theculture onto blood agar plates,or inoculating them into beef broth for cultivation at 37℃ for 4 days.Theperiod of logarithmic growth was from 48 to 72hr.After having become adapted to the in vitro environ-ment,the organisms could also grow and reproduce in the absence of vitamin—Tween 80 mixtures whichwere used at the start of the culture.So far,this axenic culture has been maintained for 6 months and 50subcultures have been made.

收集蓝氏贾第鞭毛虫患者的新鲜粪便标本,用蔗糖密度梯度离心法纯化包囊。以包囊悬液感染哺乳期的长爪沙鼠,7d 后,在无菌条件下从受染乳鼠小肠上段获取本虫滋养体,用改良 TYI-S-33培养基,于37℃培养。培养后 d4虫体即在管壁形成密集的细胞单层,同日开始传代。将培养物置肉汤及血琼脂平板培养,未见细菌及霉菌污染,为纯培养。虫体的对数生长期为48~72h。在去除培基中的维生素一吐温80混合液成分后,虫体仍可生长繁殖。

An animal model of Helicobacter felis (Hf)which is a related bacterium of Helicobacter pylori(Hp)was estalished in this study. After oral inoculation of Hf to the stomach of 25 of Specific Pathogen Free (SPF) Balb/c mice,long time colonizayion was observed. Histologic changes were mainly chronic active gastritis features. After16 weeks of infection,chronic gastritis was found in all of the 25 mice IgG antibodies with cross reaction with Hp could be detected in serum and intestinal fluid of the infectious...

An animal model of Helicobacter felis (Hf)which is a related bacterium of Helicobacter pylori(Hp)was estalished in this study. After oral inoculation of Hf to the stomach of 25 of Specific Pathogen Free (SPF) Balb/c mice,long time colonizayion was observed. Histologic changes were mainly chronic active gastritis features. After16 weeks of infection,chronic gastritis was found in all of the 25 mice IgG antibodies with cross reaction with Hp could be detected in serum and intestinal fluid of the infectious animals. Both of these findings were similar to that of Hp infection in human beings,which suggests that this model should be useful in the study of Hp.

本研究建立了幽门螺杆菌的近缘苗猪胃螺杆菌的SPF级Balb/c小鼠模型,发现细菌可在其中长期定植并引起与人类Hp相关胃炎相似的组织学改变,提示该模型可用于幽门螺杆菌的研究。

 
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