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   cervical condyloma 的翻译结果: 查询用时:0.161秒
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妇产科学
感染性疾病及传染病
皮肤病与性病
临床医学
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cervical condyloma
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  宫颈湿疣
     Results The uterus cervix rotten to the core I, II and III prevalence rates were 18.73%, 10.25% and 2.55%, the cervix of the uterus polyp prevalence rate was 17.98%, the uterus cervix hypertrophy was 23.97%, cervical condyloma was 0.40%, post-natal lacerated wound was 4.19% respectively.
     结果宫颈糜烂I度、II度和III度的患病率分别为18.73%、10.25%和2.55%,宫颈息肉患病率为17.98%,宫颈肥大为23.97%,宫颈湿疣0.40%,产后裂伤为4.19%。
短句来源
     Method In immunohistochemistry detection P16INK4A , CyclinE,CDK2 of expression(Detection P16INK4A ,CyclinE using SP method;Detection CDK2 using SABC method)and in situ hybridization detectionHPV16 in 15 nomal cervix,10 cervical condyloma ,45 CINs and 20 cervicalcarcinoma Using Tissue Microarra.
     方法 应用组织微阵列方法和免疫组化法对 15 例正常宫颈、10 例宫颈湿疣、45 例宫颈上皮内瘤样病变、20 例宫颈浸润癌行 P16INK4a、CyclinE、CDK2 的测定(SP 法检测 P16INK4a、CyclinE;SABC 检测 CDK2),用组织微阵列方法及原位杂交行 HPV16CDNA 的测定。
短句来源
     97 patients suffered cervical condyloma(23 among them with pregnancy)were treated with Ho:YAG laser(pulse energy:0.5-0.8J,frequency:5-15Hz).
     宫颈湿疣97例(包括妊娠合并宫颈湿疣23例),采用峰值能量0.5-0.8J,频率5-15Hz。
短句来源
     [Result] By pathology confirmation, there were chronicity cervicitis 187 cases, cervical polyp 46 cases, cervical condyloma acuminatum 17 cases, CIN (cervical intraepithelial neoplasia)13 cases, cervical carcinoma 2 cases.
     结果经病理证实,慢性宫颈炎187例,宫颈息肉46例,宫颈湿疣17例,宫颈上皮内瘤样病变(CIN)13例,宫颈癌2例。
短句来源
     [Result] By pathology confirmation, there were chronicity cer-vicitis 187 cases, cervical polyp 46 cases, cervical condyloma acuminatum 17 cases, CIN (cervical intraepithelial neoplasia)13 cases, cervical carcinoma 2 cases.
     结果经病理证实,慢性宫颈炎187例,宫颈息肉46例,宫颈湿疣17例,宫颈上皮内瘤样病变(CIN)13 例,宫颈癌2例。
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  宫颈尖锐
     The positive rate of HPV6/11 was significantly higher than that of HPV16/18 in cervical condyloma acuminatum with koilocytosis(P< 0.01),and the positive rate of HPV16/18 was significantly higher than that of HPV6/11 in cervical condyloma acuminatum with nuclear atypia(P< 0.01).
     具有凹空细胞的宫颈尖锐湿疣中,HPV6/11的阳性率明显高于HPV16/18的阳性率(P<0.01),以细胞核病理性改变为特征的宫颈尖锐湿疣中,HPV16/18的阳性率明显高于HPV6/11的阳性率(P<0.01);
短句来源
     Methods HPV6/11,HSV-Ⅱ and CMV of 10 cases of nomal cervix,10 chronic cervicitis,10 cervical condyloma,45 CINs and 20 cervical carcinoma were detected by the immunohistochemistry,and HPV16 cDNA by in situ hybridization.
     方法采用免疫组化方法对10例慢性宫颈炎、10例宫颈尖锐湿疣、45例宫颈上皮内瘤变、20例宫颈浸润癌、10例正常宫颈标本行HPV6/11、HSV-Ⅱ、CMV的测定。 用原位杂交行HPV16CDNA的测定。
短句来源
     The HPV antigen was expressed only in cervical condyloma acuminatum with distinct koilocytosis caused by HPV6/11 infection.
     HPV抗原的表达仅见于HPV6/11感染且凹空细胞明显的宫颈尖锐湿疣。
短句来源
     HPV6/11 is main reason for the cervical condyloma .
     HPv6/11是引起宫颈尖锐湿庆的主要病因。
短句来源
     Results Cervical condyloma showed a sigificantly higher HPV6/11 infection rate.
     结果HPV6/11在宫颈尖锐湿疣组阳性表达率明显增高(P<0.05)。
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  “cervical condyloma”译为未确定词的双语例句
     HPV6/11 is main reason for the cervical condyloma.
     结论HPV6/11是引起宫颈癌和尖锐湿疣的主要病因。
短句来源
     Cervical carcinoma and CINs showed sigificantly higher HPV16 cDNA,HSV-Ⅱand CMV infection rates than the nomal cervix,chronic cervicitis and cervical condyloma(P<0.05),the expression of HPV16 cDNA increased following progress of cervical lesions.
     HPV16 cDNA,HSV-Ⅱ及CMV在宫颈癌及宫颈上皮内瘤变中的阳性表达率均增高(P<0.05)。
短句来源
     rvical carcinoma CINs, when HPV16 infection was emerged with HSV- Ⅱ, CMV, the expression rates of HPV16E7 are higher than that of HPV16E7 when only HPV16 was infective, the expression rate of Rb increases in chronic cervicitis, cervical condyloma ,CINs .
     在宫颈癌及宫颈上皮内瘤变时,HPV16E7在HPV16合并HSV一11及CMV感染时阳性表达率高于单纯HPV16感染时的表达。
短句来源
     Methods DNA was isolated from specimens including desquamate cells of sexual organs, secretion or cervical condyloma tissues and used for PCR amplification.
     方法取子宫颈及生殖器尖锐湿疣疣体脱落细胞或尖锐湿疣组织,经PCR扩增后其产物与11种常见HPV亚型探针进行导流快速反斑点印迹杂交。
短句来源
     CONCLUSION: The staining pattern of P16 was useful to differentiate CIN with chronic cervicitis with squamous metaplasia and cervical condyloma acuminatum.
     结论P16的着色可用于CIN与慢性宫颈炎伴腺体鳞化、尖锐湿疣之间的鉴别。
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  cervical condyloma
The rate of detection of HPV-16 in Chinese women increased from 8.3% in normal cervical epithelium to 20% in chronic cervicitis, 28% in cervical condyloma, 50% in CIN and 60.4% in cervical cancer.
      
The gene expression of human papillomavirus (HPV) 33, which can be detected both in benign and malignant genital tumors, was analyzed in a cervical condyloma acuminatum by in situ hybridization using open reading frame-specific RNA probes.
      


The HPV DNA related sequences, the expression of HPV capside antigen and relationship between the ultrastructural feature of lesion and diverse types of HPV infection in 35 cases of the cervical pr61iferative lesions(cervical condyloma, cervical cancer)were analyzed on the levels of cell,subcell and molecule by using nucleic acid hybridization, immunohistochemical method and electron microscopic technique. The results showed: (1) Moot of cervical condyloma was related to HPV 11; cervical...

The HPV DNA related sequences, the expression of HPV capside antigen and relationship between the ultrastructural feature of lesion and diverse types of HPV infection in 35 cases of the cervical pr61iferative lesions(cervical condyloma, cervical cancer)were analyzed on the levels of cell,subcell and molecule by using nucleic acid hybridization, immunohistochemical method and electron microscopic technique. The results showed: (1) Moot of cervical condyloma was related to HPV 11; cervical cancer was mainly related to HPV 16. (2) The expression of HPV capside antigen presented negatine relation to malignant degree of lesion in the cervical proliferative lesion, the higher the malignant degree of lesion was, the lower the expression of HPV capside antigen was. (3) HPV 11 induced lesion characterized by a high degree of koilocytoois as a marker and HPV 16 appeared to preferentially induce lesion with marked nuclear atypia in the cervical benign proliferative lesion (cervical condyloma). (4) The expression of HPV capside antigen was much higher in the cervical benign proliferative lesion with koilocytosis caused by HPV 11, on the contray,the expression of HPV capside antigen was much lower in the cervical benign proliferative lesion with marked nuclear atypia caused by HPV 16.

本研究分别用核酸杂交、免疫组织化学和电子显微镜术等方法从细胞、亚细胞和分子水平上比较分析了35例子宫颈增殖性病变中人乳头瘤病毒DNA相关序列,人乳头瘤病毒衣壳抗原的表达以及病变超微结构变化特征与不同型别人乳头瘤病毒感染之间的关系。结果表明:(1)宫颈湿疣多与人乳头瘤病毒11型(HPV—11)相关,宫颈癌主要与人乳头瘤病毒16型(HPV—16)相关;(2)子宫颈增殖性病变中人乳头瘤病毒衣壳抗原的表达与病变的恶性程度呈负相关,病变恶性程度愈高,人乳头瘤病毒衣壳抗原的表达愈低;(3)宫颈湿疣中HPV—11以诱导细胞的重度凹空病变为标志,HPV—16以引起细胞核的非典型性改变为特征;(4)人乳头瘤病毒衣壳抗原的表达主要见于HPV—11感染的具有凹空病变的宫颈湿疣中,而在HPV—16感染引起细胞核非典型性改变为特征的宫颈湿疣中,人乳头瘤病毒衣壳抗原的表达较低。以上结果表明:HPV—16致癌潜能较强。

The Physical state of 32 cases of cervical proliferative lesions which were positive to dot blot hybridization of HPV—16DNA were further analyzed by using labelled HPV—16 DNA probe, restriction enzyme technique and Southern blot hybridization method. The results showed that HPV—16 DNA sequences could only be detected as an episome in normal cervical epithelia and cervical benign proliferative lesions(cervical condyloma),on the contray, HPV—16 DNA was found to have been integrated into the genome of host...

The Physical state of 32 cases of cervical proliferative lesions which were positive to dot blot hybridization of HPV—16DNA were further analyzed by using labelled HPV—16 DNA probe, restriction enzyme technique and Southern blot hybridization method. The results showed that HPV—16 DNA sequences could only be detected as an episome in normal cervical epithelia and cervical benign proliferative lesions(cervical condyloma),on the contray, HPV—16 DNA was found to have been integrated into the genome of host cell in of cervical malignant proliferative lesions(cervical cancer) while in the cervical malignant lesions(cervical intraepithelial neoplasia, CIN), HPV—16 DNA sequences coexisted in form of episome and integration. These results suggest that integration of HPV—16 genome in cervical epithelia may play an important role in the process of occurrence and development of cervical cancer.

本研究以a—~(32)P—dCTP标记的HPV—16DNA为探针,应用限制性内切酶技术和Southern印迹杂交方法进一步分析了32例HPV—16DNA斑点杂交阳性的宫颈活检标本中HPV—16基因组的物理状态。结果表明:正常宫颈上皮和宫颈良性增殖性病变(宫颈湿疣)中,HPV—16DNA均以染色体外游离基因的形式存在;宫颈癌前病变(宫颈上皮内新生物)中,HPV—16DNA以游离和整合两种状态共存;宫颈恶性增殖性病变(宫颈癌)中,HPV—16DNA完全以整合的形式存在于宿主细胞基因组中。以上结果提示:宫颈上皮中HPV—16基因组的整合在宫颈癌的发生发展过程中可能起着重要作用。

bjective To determine the relationship between the infection by human papillomavirus(HPV)and the incidence of cervical carcinoma. Methods Biopsy and paraffin wax embedded specimens(n=99 ) from various cervical lesions in the departrnent of gynecologic oncology were analysed by polymerase chain reaction(PCR )technique with multiple primers of HPV types 6b/11 , 16 and 18.Resul ts Of 9 9 cervical specimens investigated,2 0 were histopathologically diagnosed as cervical condyloma, 18 as cervical intraepithelial...

bjective To determine the relationship between the infection by human papillomavirus(HPV)and the incidence of cervical carcinoma. Methods Biopsy and paraffin wax embedded specimens(n=99 ) from various cervical lesions in the departrnent of gynecologic oncology were analysed by polymerase chain reaction(PCR )technique with multiple primers of HPV types 6b/11 , 16 and 18.Resul ts Of 9 9 cervical specimens investigated,2 0 were histopathologically diagnosed as cervical condyloma, 18 as cervical intraepithelial neoplasia(CIN ) grade 1~2(CIN_(1~2)), 20 as CIN grade 3(CIN_3),2 3 as cervical cancer and 1 8 as normal controls. Detection for HPV revealed that the positive rates of the five different groups were 85.0%, 83.3%, 80.0%, 87.0%and 27.8%,respectively. Those of the cervical lesions were significantly higher than that of the normal controls(P<0. 01). The predominant HPV type in condyloma and CIN_(1~2) group were HPV 6b/11 (positive rates 85.0%and72.3%), while HPV 16 and(or)18 DNA were more frequently found in the CIN_3 group(50.0%)and in the cervical cancer group(73.9%), The difference of distribution of HPV types in cervical condylo-ma,CIN_(1~2) and in CIN_3,and cervical carcinoma was statistically significant(P<0.01)。Concl usion HPV infections are intimately linked to condyloma , CIN and carcinoma of the uterine cervix; the low-risk types HPV 6 and 11 seem to be associated with cervical condyloma and the low grade CIN; the high-risk types 16 and 18 are closely related to high grade CIN and cervical carcinom,

应用多重引物人乳头状瘤病毒(HPV)6B/11、16、18 型聚合酶链反应(PCR)技术检测99例不同宫颈病变宫颈组织中人乳头状瘤病毒DNA(HPVDNA)。其中宫颈湿疣20例,宫颈上皮内瘤变(CIN)1~2级(CIN_(1~2))18例,CIN3级(CIN_3)20例,宫颈癌23例和正常对照18例。结果:上述宫颈组织中HPVDNA总检出率分别为85.0%,83.3%,80.0%,87.0%和27.8%。宫颈各病变组中HPVDNA的检出率均显著高于对照组(P<0.01)。宫颈湿疣及CIN_(1~2)中HPV6B/11型检出率分别为85.0%和72.3%,CIN_3和宫颈癌中HPV6和(或)18型阳性率分别为50.0%和73.9%,两者HPV型别分布差异有显著意义(P<0.01)。3例腺癌中HPV18型阳性2例,16型阳性1例。低分化宫颈癌中均为HPV16和(或)18型感染。提示:宫颈癌及其癌前病变的发生与HPV感染高度相关。宫颈湿疣和CIN_(1~2)常与HPV6B/11型感染有关;CIN_3和宫颈癌的发生则与HPV16、18型关系密切。

 
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