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hydrogen peroxide
相关语句
  过氧化氢
    Determination of Chemical Stability of Hydrogen Peroxide Dilute Solution by Agar Diffusion Test
    琼脂弥散法测定过氧化氢稀溶液的化学稳定性
短句来源
    RESULTS Geniposide is a novel agonist for GLP-1 receptor, which induces the neuronal differentiation of PC12 cells via mitogen-activated protein kinase pathway, and prevents PC12 cells from oxidative damage induced by hydrogen peroxide.
    结果经过筛选、鉴定,京尼平苷是一种新的GLP-1受体激动剂,能够通过MAPK信号通路诱导PC12细胞分化,对抗过氧化氢诱导的PC12细胞氧化损伤,提高神经细胞活力。
    Then their ability to protect PC12 cells against hydrogen peroxide induced apoptosis was assessed through MTT methods.
    通过MTT方法考察了上述化合物对PC12细胞的保护作用以及对于由过氧化氢诱导产生的氧化应激损伤的PC12细胞凋亡的抑制作用。
    EXPERIMENTAL OBSERVATION ON GERMICIDAL EFFICACY OF COMPOUND DISINFECTANT OF HYDROGEN PEROXIDE
    过氧化氢复方消毒剂杀灭微生物效果的实验观察
短句来源
    Protective Effects of TMB-8 on Hydrogen Peroxide Induced Injury in Bovine Aortic Endothelial Cells
    内钙拮抗剂TMB-8对过氧化氢所致的培养牛主动脉内皮细胞损伤的保护作用
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  双氧水
    Penicillin G potassium salt can be oxidized by Hydrogen Peroxide or Peracetic acid to give sulfoxide with a yield of 91.5%.
    以青霉素 G钾为原料 ,分别采用过氧乙酸和双氧水作氧化剂合成青霉素 G亚砜 ,收率可达91.5 %。
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  “hydrogen peroxide”译为未确定词的双语例句
    The Protective Effects of N-Acetylcysteine on Exogenous Hydrogen Peroxide and Endogenous Superoxide Anion-induced DNA Strand Breakage in Human Spermatozoa
    N-乙酰半胱氨酸对外源性H_2O_2和内源性O_2~-引起的精子DNA损伤的保护作用
短句来源
    DNA Oxidative Damage Induced by Oxidants and P-tyrosol Protection Against Hydrogen Peroxide in CHL Cells
    氧化剂致CHL细胞DNA损伤及酪醇的保护作用
短句来源
    Effects of N-acetyl-L-cystein on endothelial cells injury induce by hydrogen peroxide
    N-乙酰-L-半胱氨酸对H_2O_2引起的血管内皮细胞损伤的拮抗效应
短句来源
    Effect of Abnormal Savda Munziq and Mushil on the expression of nuclear factorκB induced by hydrogen peroxide in lymphocytes
    异常黑胆质成熟剂与清除剂对H_2O_2诱导的淋巴细胞NF-κB表达的影响
短句来源
    Antiapoptotic Effect and Its Mechanism of Rosmarinic Acid on Human Umbilical Vein Endothelial Cell Apoptosis Induced by Hydrogen Peroxide
    迷迭香酸拮抗H_2O_2诱导的人脐静脉内皮细胞凋亡及作用机制
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  hydrogen peroxide
Their catalytic activity in the oxidation of cyclohexanol and benzyl alcohol was investigated with only aqueous 30% hydrogen peroxide.
      
Electrochemical behavior of hydrogen peroxide sensor based on new methylene blue as mediator
      
A novel amperometric hydrogen peroxide sensor was proposed by co-immobilizing new methylene blue (NMB) and Horseradish peroxidase (HRP) on glassy carbon electrode through covalent binding.
      
The experiments showed NMB could effectively transfer electrons between hydrogen peroxide and glassy carbon electrode.
      
The oxidant was a 30 wt-% aqueous solution of hydrogen peroxide.
      
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The inorganic salts of antimony, arsenic and bismuth are toxic substances, but their hard dissociated organic derivatives are less toxic and are widely used in the- rapy. Organic chelating compounds such as ethylenediaminetetraacetic acid (I) are often used as agents for detoxification of heavy metals. It appears that complexes formed by therapeutic metals and ethylenediaminetetraacetic acid would be less toxic as well and might be useful therapeutically. Such compounds have been prepared in the present work....

The inorganic salts of antimony, arsenic and bismuth are toxic substances, but their hard dissociated organic derivatives are less toxic and are widely used in the- rapy. Organic chelating compounds such as ethylenediaminetetraacetic acid (I) are often used as agents for detoxification of heavy metals. It appears that complexes formed by therapeutic metals and ethylenediaminetetraacetic acid would be less toxic as well and might be useful therapeutically. Such compounds have been prepared in the present work. Attempts to react ethylenediaminetetraacetic acid or its mono, di or tetra-sodi- um salts with freshly precipitated antimonous oxide were not successful. The former also failed to react with potassium antimonyltartrate. Treatment of antimony trichloride on aqueous ethylenediaminetetraacetic acid, however, gave a complex, which could be recrystallized from water without hydrolysis, and which gave no precipitate with catechol or rhodizonic acid. This complex forming reaction is most favourable at a pH of about 2.5. Neutralization of the complex with various alkalis or amines afforded the corresponding potassium, sodium, lithium, ammonium, ethylenediammonium and diethylammonium salts, which are water-soluble. Neither antimony pentachloride nor arsenic trichloride gave the corresponding chelating compounds with ethylenediaminetetraacetic acid under similar conditions. A bismuth chelate was formed by interaction of bismuth basic carbonate and aqueous ethylenediaminetetraacetic acid at 80°. This sparingly soluble chelate gave water-soluble salts on treatment with sodium hydroxide or ammonia. In order to study its structure, a pseudo-ephedrine salt, m. p. 270-271° (decomp.), (α)_D~(10)=-1.28,° was prepared. Recrystallization of this salt, however, did not cause change in optical rotation. Structure II should give optical isomers. An alternative symme- trical structura was recently suggested by Japanese authors. It was shown in our previous work that stannous tin could yield potential therapeutic compounds. Attempts were therefore made to prepare a stannous chelate of ethylenediaminetetraacetic acid. Although treatment of the latter with stannous oxide did not afford a pure compound, its disodium salt and stannous chloride interacted smoothly in water and a chelate was formed. This new com- pound gave no precipitate on treatment with alkalis, oxalate or sodium thiosulphate, but it could reduce mercuric salts, and metallic tin was separated on treatment with zinc. A water-soluble diammonium salt was prepared. Oxidation of the stannous chelate of ethylenediaminetetraacetic acid by means of hydrogen peroxide afforded the corresponding stannic chelate. Since it could not be dehydrated under reduced pressure and its aqueous solution was distinctly acidic, its structure was assumed as a tetradentate ligand (Ⅲ) rather than a hexadentate one (Ⅳ). It was recently shown by Indian authors that tervalent metals did not necessarily give hexadentate ligand chelates. The stannic chelate is less stable toward alkali than the stannous compound. Preliminary pharmacological tests revealed that the sodium salt of the antimony chelate was as active as tartar emetic against schistosomiasis japonica in white mice.

乙二胺四乙酸在醋酸及醋酸钠缓冲溶液中与三氯化锑作用,获得锑螯合物;与碱式碳酸铋作用,获得铋螯合物;它的二钠盐与氯化亚锡作用,获得亚锡螯合物;作用过程中以过氧化氢氧化时形成锡螯合盐.这些金属螯合物并经与各种碱或胺作用,制成多种水溶性盐。对血吸虫病实验治疗的初步结果指示锑螯合物钠盐的疗效与酒石酸锑钾相仿。

Potassium antimonyltartrate (Ⅰ) is an effective schistosomacidal agent. It would be of interest to see the activity of its corresponding pentavalent antimony derivative. Furthermore, chelation of the latter compound with various hydroxy acids would give a series of new compounds with different degree of stability, which might have some relations with their pharmacological properties. Treatment of aqueous potassium antimonyltartrate (Ⅰ) with 30% hydrogen peroxide gave the corresponding pentavalent antimonyltartrate...

Potassium antimonyltartrate (Ⅰ) is an effective schistosomacidal agent. It would be of interest to see the activity of its corresponding pentavalent antimony derivative. Furthermore, chelation of the latter compound with various hydroxy acids would give a series of new compounds with different degree of stability, which might have some relations with their pharmacological properties. Treatment of aqueous potassium antimonyltartrate (Ⅰ) with 30% hydrogen peroxide gave the corresponding pentavalent antimonyltartrate (Ⅱa). This compound is a weak acid, forms a di-potassium salt (Ⅱb) with potassium hydroxide but does not react with weak bases such as diethylamine or pyridine. Ⅱa, on boiling with potassium bitartrate, gave di-potassium antimonyl~(V) ditartrate (Ⅲ). This new compound could also be formed by the oxidation of antimony trichloride by means of hydrogen peroxide followed by chelation with tartaric acid and then neutralization with potassium hydroxide. Similar complexes were prepared by the action of glyceric acid, D-gluconic acid, mucic acid and gallic acid on Ⅱa. These new compounds are water-soluble substances, and they are suitable for injection. Preliminary pharmacological examination showed that they had quite low toxicity.

酒石酸銻鉀(Ⅰ)用过氧化氫氧化后生成相应五价銻化合物(Ⅱa),它与二乙胺或吡啶等弱碱不能成鹽,但与氫氧化鉀生成鉀鹽(Ⅱb),酒石酸銻鉀(Ⅱa)与酒石酸氫鉀、甘油酸、葡萄糖酸、半乳糖二酸及沒食子酸作用,生成相应于Ⅲ結構的螯合鹽。

In view of the cffectivcness of bis(3,5,6-trichloro-2-hydroxyphenyl)-sulphide (I_b, CMS-390) and bis(3-bromo-5-chloro-2-hydroxyphenyl)_sulphide(I_a, CMS-349) in the treatment of schistosomiasis japonicum, a series of analogous compounds was prepared in the present work for pharmacological examinations. The compounds I_2 and I_b were oxidized with hydrogen peroxide, forming the corresponding sulphoxides (II_2 and II_b). The compound substituted with mixed halogens (I_c) was prepared by bromination of the...

In view of the cffectivcness of bis(3,5,6-trichloro-2-hydroxyphenyl)-sulphide (I_b, CMS-390) and bis(3-bromo-5-chloro-2-hydroxyphenyl)_sulphide(I_a, CMS-349) in the treatment of schistosomiasis japonicum, a series of analogous compounds was prepared in the present work for pharmacological examinations. The compounds I_2 and I_b were oxidized with hydrogen peroxide, forming the corresponding sulphoxides (II_2 and II_b). The compound substituted with mixed halogens (I_c) was prepared by bromination of the corresponding chloro-compound. When phenols with various substituents were reacted with sulphur chloride, the corresponding diphenyl sulphides were obtained. The Mannich bases were obtained by heating 2,2'-dihydroxydiphenyl sulphides with formaldehyde and secondary amines. The piperazine salts were prepared by coupling the corresponding diphenyl sulphides with anhydrous piperazine. Preliminary pharmacological examinations showed that bis (3-bromo-4,5-dichloro-2-hydroxyphenyl)-sulphide (I_c), bis (3-bromo-5-chloro- 2-hydroxyphenyl)-sulphoxide (II_2), bis (3,5,6-trichloro-2-hydroxyphenyl)-sulphoxide (II_b) and the piperazine salt of bis(3-bromo-5-chloro-2-hydroxyphenyl_-sulphide and bis(3,5,6- trichloro-2-hydroxyphenyl)-sulphde were quite effective against Schistosoma japonicum.

鉴于2,2'-二羟基-3,3'-二溴代-5,5'-二氯代二苯硫醚(I_a,抗虫349)与2,2'-二羟基-3,3',5,5',6,6'-六氯代二苯硫醚(I_b抗虫390)对小白鼠体内的日本血吸虫具有明显的抑制与杀灭作用,乃合成一系列有关化合物。亚砜化合物(II_a、II_b)系由相应的硫醚(I_a、I_b)在冰醋酸中用过氧化氢氧化制成。2,2'-二羟基-4,4',5,5'-四氯代二苯硫醚(I_d)用溴素溴化得化合物I_c。化合物I_(d-f)系由苯环上带有相应取代基的苯酚与二氯化硫缩合而得。化合物I_(g-o)系由对位带有各种不同基因(Cl、Br、CH_3等)的2,2'-二羟基二苯硫醚、甲醛与相应的仲胺在乙醇中进行Mannich反应而得。化合物I_a、I_b溶于苯中与无水(?)(?)嗪苯溶液作用分别得相应的(?)(?)嗪盐。动物试验结果指出2,2'-二羟基-3,3'-二溴代-4,4',5,5'-四氯代二苯硫醚(I_c,编号抗虫438)、2,2'-二羟基-3,3'-二溴代-5,5'-二氯代二苯亚砜(II_a,编号抗虫436)、2,2'-二羟基-3,3',5,5',6,6'-六氯代二苯亚砜(II_b,编号抗虫42...

鉴于2,2'-二羟基-3,3'-二溴代-5,5'-二氯代二苯硫醚(I_a,抗虫349)与2,2'-二羟基-3,3',5,5',6,6'-六氯代二苯硫醚(I_b抗虫390)对小白鼠体内的日本血吸虫具有明显的抑制与杀灭作用,乃合成一系列有关化合物。亚砜化合物(II_a、II_b)系由相应的硫醚(I_a、I_b)在冰醋酸中用过氧化氢氧化制成。2,2'-二羟基-4,4',5,5'-四氯代二苯硫醚(I_d)用溴素溴化得化合物I_c。化合物I_(d-f)系由苯环上带有相应取代基的苯酚与二氯化硫缩合而得。化合物I_(g-o)系由对位带有各种不同基因(Cl、Br、CH_3等)的2,2'-二羟基二苯硫醚、甲醛与相应的仲胺在乙醇中进行Mannich反应而得。化合物I_a、I_b溶于苯中与无水(?)(?)嗪苯溶液作用分别得相应的(?)(?)嗪盐。动物试验结果指出2,2'-二羟基-3,3'-二溴代-4,4',5,5'-四氯代二苯硫醚(I_c,编号抗虫438)、2,2'-二羟基-3,3'-二溴代-5,5'-二氯代二苯亚砜(II_a,编号抗虫436)、2,2'-二羟基-3,3',5,5',6,6'-六氯代二苯亚砜(II_b,编号抗虫422)、以及2,2'-二羟基-3,3'-二溴代-5,5'-二氯代二苯硫醚、2,2'-二羟基-3,3',5,5',6,6'-六氯代二苯硫醚的(?)(?)嗪盐对小白鼠体内的日本血吸虫均有明显的抑制与杀灭作用,详细的药理结果将另文报导。

 
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