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intervention effect
相关语句
  干预作用
    Expression of Granzyme B in Myocardium of Mice with Viral Myocarditis and Intervention Effect of Qingxin Capsule on it
    病毒性心肌炎小鼠心肌颗粒酶B的表达及清心胶囊的干预作用
短句来源
    Intervention effect of local application of recombinant hirudin on neuronal apoptosis in intracerebral hemorrhage of rats
    局部应用重组水蛭素对大鼠脑出血神经细胞凋亡的干预作用
短句来源
    Advances in studies on intervention effect of Chinese materia medica on blood-brain barrier
    中药对血脑屏障干预作用的研究进展
短句来源
    Intervention Effect of Puerarin on Expressions of HSP70 and Fas Proteinum in Rats with Acute Cerebral Ischemia Injury
    葛根素对急性脑缺血模型大鼠脑细胞损伤后HSP70及Fas蛋白表达的干预作用研究
短句来源
    Effects of Long-term High-fat Feeding on PKC Activation in Rats Kidneys and Intervention Effect of Compound Herbal Medicine
    长期高脂饲养大鼠肾脏PKC活性的变化及复方中药的干预作用
短句来源
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  干预效应
    Intervention effect of shenxian tang on the learning and memory power of rats with multiple cerebral infarction dementia
    参仙汤对多发性脑梗死性痴呆大鼠学习记忆能力的干预效应(英文)
短句来源
    Objective:Using aspect of neuroendocrine — immunoregulatory network to probe nosogenesis of stress ulce, to explain the intervention effect of the TCM compound shenxinlhao.
    目的:从神经-内分泌-免疫网络的角度来探讨应激性溃疡的发病机制,阐述中药复方心身1号的干预效应
短句来源
    To observe the intervention effect of dragon’s blood total flavone on VGSC in order to clarify the utility part of analgesia induced by dragon’s blood.
    观察血竭总黄酮对其的干预效应,以阐明血竭产生镇痛效应的有效部位。
短句来源
    AIM: To observe the intervention effect of shutangbao on blood glucose, blood lipid, glucose and urine protein in rats with diabetes.
    目的:观察以荔枝为主要原料的复方口服液舒糖宝对糖尿病大鼠血糖、血脂、尿糖、尿蛋白的干预效应。 方法:①实验于2004-10-05/10-22在广西右江民族医学院生化教研室实验室完成。
短句来源
  “intervention effect”译为未确定词的双语例句
    The Relationship between ET,TGF-β and Diabetic Nephropathy, and the Intervention Effect of Cordycepic Hypha
    ET、TGF-β与糖尿病肾病的关系及虫草菌丝对其影响的实验研究
短句来源
    Study on the intervention effect of Qileng decoction (芪棱汤) on mitochondria mediated and caspase-9 dependent apoptopic pathway
    芪棱汤对线粒体介导caspase-9依赖凋亡通路的干预
短句来源
    Expression of nNOS mRNA of brain tissue at early stage of intracerebral hemorrhage in rats and the intervention effect of Didangtang
    大鼠脑出血早期脑组织神经元型一氧化氮合酶mRNA表达及中药抵当汤干预对其的影响
短句来源
    A Study of Intervention Effect of Qingkailing in Epileptic Rat
    清开灵对戊四氮致癎大鼠的干预研究
短句来源
    It was suggestd the Intervention effect of Sagittaria agittifolia on rats lipid peroxidation caused by cadmiun.
    提示较高剂量的慈菇汁具有拮抗Cd 致大鼠脂质过氧化反应的作用。
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  intervention effect
An additional 245 abstainers and light drinkers who were also randomized to condition did not show any intervention effect.
      
A generalized estimating equations model yielded a significant intervention effect on all three composite outcome variables.
      
Results suggest that the latent variable growth modeling (LGM) is capable of detecting simultaneous differences in both level and slope, and provides tests of significance for these two necessary indicators of an ITS intervention effect.
      
Among multiparas we found an intervention effect on sensitivity, with control group mothers showing an increase in sensitivity, whereas the intervention group showed a constant level of sensitivity over time.
      
Furthermore, we witnessed an unexpected intervention effect that the diary may have in the lives of drug users.
      
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In order to investigate the effect of Sagittaria agittifolia on rats lipid peroxidation caused by cadmium(Cd),wistar's rats(devided into 6 groups equal in male and female)was used to experiment with 6 weeks observation.To measure serum and liver lipid peroxide(LPO) concentration,the GSH px activity,the contents of cadmium in liver were determined.The results showed that the serum LPO of middle and high dose of Sagittaria agittifolia treatment groups decreased remarkablely comparing with Cd treatment group.The...

In order to investigate the effect of Sagittaria agittifolia on rats lipid peroxidation caused by cadmium(Cd),wistar's rats(devided into 6 groups equal in male and female)was used to experiment with 6 weeks observation.To measure serum and liver lipid peroxide(LPO) concentration,the GSH px activity,the contents of cadmium in liver were determined.The results showed that the serum LPO of middle and high dose of Sagittaria agittifolia treatment groups decreased remarkablely comparing with Cd treatment group.The Cd in liver of three dose of Sagittaria agittifolia treatment groups was also decreased remarkablely comparing with Cd tmatment group,and no difference between high dose of Sagittarittifolia treatment groups and vitamin E treatment groups.The LPO in liver of three dose of Sagittaria agittifolia treatment groups was not remarkable difference comparing with Cd treatment group and vitamin E treatment groups.The GSH px activity of high dose of Sagittaria agittifolia treatment groups was increased remarkablely comparing with Cd treatment group and vitamin E treatment grops.It was suggestd the Intervention effect of Sagittaria agittifolia on rats lipid peroxidation caused by cadmiun.

为探讨慈菇对镉致大鼠脂质过氧化反应的干预作用,采用纯种Wistar 大鼠,随机分为6组:正常对照组、镉处理组、阳性对照组、低剂是干预组、中剂量干预组和高剂量干预组,连续观测6 周。观察血清及肝匀浆脂质过氧化物(LPO) 、肝匀浆谷胱甘肽过氧化物酶( GSHpx) 、血浆及肝组织镉(Cd)含量等指标。结果显示中剂量和高剂量干预组的血LPO 均比镉处理组明显降低(P< 0-05) ,而与阳性对照组无差别:3 个剂量干预组肝组织Cd 含量均比镉处理组明显降低,高剂量组的肝组织Cd 与阳性对照组无差别;3 个剂量干预组肝匀浆LPO 与镉处理组及阳性对照组均无明显差别;高剂量干预组的GSHpx 比镉处理组及阳性对照均明显增高。提示较高剂量的慈菇汁具有拮抗Cd 致大鼠脂质过氧化反应的作用。

Objective To research the effect of nitric oxide in the process of cadmium-induced acute liver injury and intervention with Sagittaria Sagittifolia.Methods Thirty male Sprague-Dawley rats were randomly assigned into six groups,each of six.The rats were pretreated intragastrically with 25%,50%, 75% Sagittaria Sagittfolia extract(2ml/100g) or distilled water once daily for ten days.Twenty-four hours after the last dosing,animals were administered with CdCl 2 (20μmol/L/kg) intraperitoneally,control animals were...

Objective To research the effect of nitric oxide in the process of cadmium-induced acute liver injury and intervention with Sagittaria Sagittifolia.Methods Thirty male Sprague-Dawley rats were randomly assigned into six groups,each of six.The rats were pretreated intragastrically with 25%,50%, 75% Sagittaria Sagittfolia extract(2ml/100g) or distilled water once daily for ten days.Twenty-four hours after the last dosing,animals were administered with CdCl 2 (20μmol/L/kg) intraperitoneally,control animals were given distilled water only.Twenty-four hours after the intoxication,the serum LDH,GPT activity and NO concentration,liver MDA content and nitric oxide synthase (NOS) activity were measured in each group above.Results Compared to the control,cadmium could increase the serum LDH,GPT activity and liver MDA content( P <0.05); Treatment of rats with 50% and 75% Sagittaria Sagittifolia extract could decrease the serum LDH,GPT activity and liver MDA content( P <0.05);Sagittaria Sagittifolia extract inhabited liver NOS activity and decrease serum NO concentration in dose-dependent manner ( r=-0.959 6,-0.995 6,P <0.05 ) also.Conclusion It is suggested that NO seems to be involved in cadmium-induced acute peroxidative liver injury on rats and the intervention effect of Sagittaria Sagittifolia on rats.

目的 探讨NO在镉致急性肝损伤中的作用以及慈菇的干预效果。方法  30只雄性SD大鼠随机分为 5组 ,每组 6只 ,分别用 2 5 %、5 0 %、75 %的慈菇 (2ml/ 10 0 g体重 )及等体积蒸馏水灌胃 10天 ,未次灌胃 2 4h后 ,腹腔注射Cd Cl2 (2 0 μmol/L/kg体重 )或蒸馏水 ,染毒 2 4h后 ,观察血清NO含量、GPT、LDH活力及肝组织NOS活力、MDA合量。结果 CdCl2 组与阴性对照组比较 ,血清LDH、GPT活力 ,肝组织MDA合量显著升高 (P <0 0 5 ) ,中、高浓度慈菇干预组相比CdCl2 组LDH、GPT活力及MDA含量显著降低 (P <0 0 5 ) ;血清中NO含量及肝组织NOS活性各组间无明显差异 (P >0 0 5 ) ,不同浓度慈菇对肝组织NOS活性及血清NO浓度的降低具有剂量反应关系 (r分别为 - 0 95 96、-0 995 6 ,P <0 0 5 )。结论 NO可能参与镉所致肝脏的急性过氧化损伤 ,提示慈菇对镉致肝急性损伤具有保护作用

To assess the significance of platelet activation in unstable angina pectoris (UA) and acute myocardial infarction (AMI), and to explore the relationship of clinical effect of Xuefu Zhuyu concentrated pill (XCP) in vivo and the serum pharmacological anti platelet activating effect of XCP in vitro. Methods: By flow cytometry and special labelled antibodys to detect the whole blood platelet membranous glycoprotein CD62P and CD41/45 expressions in UA patients before and after XCP treatment, as well as those in...

To assess the significance of platelet activation in unstable angina pectoris (UA) and acute myocardial infarction (AMI), and to explore the relationship of clinical effect of Xuefu Zhuyu concentrated pill (XCP) in vivo and the serum pharmacological anti platelet activating effect of XCP in vitro. Methods: By flow cytometry and special labelled antibodys to detect the whole blood platelet membranous glycoprotein CD62P and CD41/45 expressions in UA patients before and after XCP treatment, as well as those in peripheral blood of AMI rats before and after co cultured with XCP containing serum from patients at 37℃ for 30 min. Results: CD62P and CD41/45 expressions increased significantly in UA patients to 24.36±7.91% and 29.51±12.21% respectively. After effective treatment, they decreased to 19.57±7.22% and 20.87±8.73% respectively accompanied with increase of platelet adhesion and aggregation rate. The difference of CD62P before and after treatment was significant (P<0 05). CD62P in blood of AMI rats was 39.73±12.36%,after being co cultured with XCP containing serum from patients treated effectively, it reduced to 30.41±10.36% (P<0 05), but after co cultured with the serum from patients treated ineffectively, it showed less intervention effect (P>0 05). Conclusion: Platelet was highly activated in UA patients and AMI rats. The consistency between clinical holistic effect of XCP and serum pharmacological effect of XCP in platelet activation inhibition reflects a good correlation between serum pharmacological effect of Chinese herbal medicine and its clinical holistic effect.

目的 :探讨血小板活化在不稳定性心绞痛 (unstableanginapectoris ,UA)和急性心肌梗死 (a cutemyocardialinfarction ,AMI)中的意义以及血府逐瘀浓缩丸抗血小板活化的临床疗效与其体外血清药理作用的相关性。方法 :采用流式细胞技术和特异性标记抗体 ,检测口服血府逐瘀浓缩丸前后UA患者全血血小板膜糖蛋白CD6 2P和CD4 1/ 4 5的表达 ,并以UA患者的含药血清与AMI模型大鼠的外周血体外共温育后 ,检测大鼠CD6 2P水平。结果 :UA患者CD6 2P及CD4 1/ 4 5表达量增高 ,分别为 (2 4 36± 7 91) %和(2 9 5 1± 12 2 1) % ,经有效治疗后降至 (19 5 7± 7 2 2 ) % (与治疗前比较 ,P <0 0 5 )和 (2 0 87± 8 73) % ;同时血小板粘附和聚集率增高。AMI大鼠CD6 2P为 (39 73± 12 36 ) % ,与有效病例的含药血清作用后降至(30 4 1± 10 36 ) % (与温育前比较 ,P <0 0 5 ) ,而疗效不佳患者的药后血清干预作用则较差 ...

目的 :探讨血小板活化在不稳定性心绞痛 (unstableanginapectoris ,UA)和急性心肌梗死 (a cutemyocardialinfarction ,AMI)中的意义以及血府逐瘀浓缩丸抗血小板活化的临床疗效与其体外血清药理作用的相关性。方法 :采用流式细胞技术和特异性标记抗体 ,检测口服血府逐瘀浓缩丸前后UA患者全血血小板膜糖蛋白CD6 2P和CD4 1/ 4 5的表达 ,并以UA患者的含药血清与AMI模型大鼠的外周血体外共温育后 ,检测大鼠CD6 2P水平。结果 :UA患者CD6 2P及CD4 1/ 4 5表达量增高 ,分别为 (2 4 36± 7 91) %和(2 9 5 1± 12 2 1) % ,经有效治疗后降至 (19 5 7± 7 2 2 ) % (与治疗前比较 ,P <0 0 5 )和 (2 0 87± 8 73) % ;同时血小板粘附和聚集率增高。AMI大鼠CD6 2P为 (39 73± 12 36 ) % ,与有效病例的含药血清作用后降至(30 4 1± 10 36 ) % (与温育前比较 ,P <0 0 5 ) ,而疗效不佳患者的药后血清干预作用则较差 (P >0 0 5 )。结论 :UA患者和AMI大鼠的血小板活化增强。血府逐瘀浓缩丸含药血清药理与临床整体药效在抑制血小板活化作用上的一致性 ,反映出中药血清药理作用与临床整体药效的良好相关性。

 
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