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cervical lesions
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  宫颈病变
     A mutation, E6-D32E (T96G) coincided with a specific type of E7 mutation, N29S (A86G). D32E/N29S mutation rate was 38.9%(28/72), the detection rate increased with the severity of cervical lesions (P<0.05).
     氨基酸序列E6-D32E(T96G)和E7-N29S(A86G)位点突变同时伴随存在,D32E/N29S的检出率为38.9%(28/72),与宫颈病变程度相关(P<0.05)。
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     To Study the P16~(INK4A) in Cervical Lesions
     P16~(INK4A)在宫颈病变中的研究
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     Expression of human papillomavirus16 cDNA and HPV6/11,HSV-Ⅱand CMV proteins in cervical lesions
     人宫颈病变组织中HPV16 cDNA,HPV6/11,HSV-Ⅱ,CMV病毒蛋白的表达及对HPV16E7的影响
短句来源
     (4)The rate of HPV-16 integration was associated with the degree of cervical lesions. Moreover,the rate increased with the progression of cervical disease,42.9% for CINⅠ,76.5% for CINⅡ,83.3% for CINⅢ and 90.2% for SCC;
     (4)HPV-16整合发生率与不同程度的宫颈病变有关,CINⅠ、CINⅡ、CINⅢ和SCC中HPV-16整合发生率分别为42.9%、76.5%、83.3%和90.2%;
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     Expression and Significance of Cox-2 and Bcl-2 in Cervical Lesions
     Cox-2,bcl-2在宫颈病变中的表达和意义
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  子宫颈病变
     Relationship of HPV CP8304 and cervical lesions
     CP8304亚型人乳头瘤病毒感染与子宫颈病变的关系
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     [Results] The sensitivity, specificity and accuracy of colposcopy for cervical lesions in our hospital is 85.2%, 52.4%, 72% and 72.6% respectively.
     结果阴道镜检查诊断子宫颈病变的敏感性85.2%,特异性52.4%,符合率72%,阳性预测值72.6%。
短句来源
     Cervical lesions were diagnosed by biopsies as normal, CIN 1, CIN 2-3, and squamous cervical cancer(SCC).
     子宫颈病变按照病理诊断分为正常、CIN1、CIN2~3和子宫颈癌(SCC)。
短句来源
     The odds ratio (OR) between low viral load of HPV DNA and CIN1 was 1.7 (0.5~7.2) while between high viral load and CIN3 OR was 88.6 (11.6~676.7) which showed that higher viral load could increase the risk of cervical lesions (P<0.001).
     从低度病毒载量与CIN1的相对危险度(OR)为1.7(0.5~7.2)至高度病毒载量与CIN3的OR值为88.6(11.6~676.7),显示出感染病毒载量与子宫颈病变程度呈正相关(P<0.001)。
短句来源
     The odds ratio(OR)between low viral load of HPV DNA and CIN 1 was 3.8(1.9-7.3) while between high viral load and CIN 2-3 was OR=865.9(200.1-3738.0)which showed that higher viral load could increase the risk of cervical lesions(P<0. 001).
     从低度病毒载量与CIN1的危险比值比(OR)为3.8(1.9~7.3)至高度病毒载量与CIN2~3的OR值为865.9(200.1~3738.0),显示出感染病毒载量与子宫颈病变程度呈正相关(P<0.001)。
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  宫颈疾病
     Conclusion: The positive expressions of p16INK4A and p14ARF were closely related to consecutive cervical lesions. p16INK4A and p14ARF might play roles in the formation and progression of cervical cancer. The expression levels of p16INK4A and p14ARF might be referred as markers of squamous carcinoma of the cervix.
     结论:p16INK4A和p14ARF蛋白的阳性表达与宫颈疾病的严重程度密切相关,在宫颈鳞癌的形成及进展中起重要作用,p16INK4A和p14ARF蛋白基因有可能成为预测宫颈鳞癌发生及病程进展的生物学检测指标。
短句来源
     Methods 261 outpatients with cervical lesions in our hospital were tested by HPV DNA testing and TCT,Cytological diagnosis was used The Besthad System (2001).
     方法对我院妇科门诊261例宫颈疾病患者进行TCT检查和HPV DNA检测,细胞学诊断标准按照TBS(2001)分类。
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     Application of hysteroscopic electrosurgery for cervical lesions
     宫腔镜电切术在宫颈疾病中的应用
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     Methods A total of 209 patients with cervical lesions including cervical epithelial neoplasia,cervical HPV infection,cervical polyp and condyloma,and severe cervicitis were performed LEEP in our hospital.
     方法对宫颈上皮内瘤样病变(C IN)、人类乳头瘤病毒(HPV)感染、宫颈赘生物、宫颈湿疣及中重度宫颈糜烂共209例宫颈疾病患者行宫颈LEEP手术。
短句来源
     Conclusions Digital colposcope can be a very accurate diagnostic method in clinical practice. The RCI can predict the severity of cervical lesions.
     结论电子阴道镜用于诊断宫颈疾病较准确可靠,有一定的临床应用价值,而RCI可预示宫颈病变的严重程度。
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  “cervical lesions”译为未确定词的双语例句
     the patients with cervical lesions(CIN) was 32,the HPV16/18 positive rate was 62.50%(20/32),CMV7 was 21.87%;
     32例宫颈癌前病变(CIN)中检出HPV16/18型20例(阳性率62.50%),CMV7例(阳性率21.87%)。
短句来源
     With HPV_(16,18) and HPV_(11) DNA probes, 80 cervical lesions and 6 other tissues were done to study human papillomaviruses (HPV) DNA sequences by dot blot hybridization. It showed that the positive rates of HPV_(16,18,11) DNA sequences in cervical cancer, cervical dysplasia and chronic cervicitis were 44% (22/50) , 8% (4/50) and 4% (2/50);
     应用HPV_(16,18,11)三个DNA探针,通过斑点杂交技术,对80例宫颈疾患和6例其它组织进行了检测和分析,结果显示HPV_(16、18)和HPV_(11)DNA序列在宫颈癌、宫颈不典型增生和慢性宫颈炎中的检出率分别为44%(22/50),8%(4/50),4%(2/50);
短句来源
     [Objective]To study the alterations of biological behavior and the expressions of HPV16/E6E7 and ERβ of immortalized cervical cell line End1/E6E7 affected by 17-β-E 2, and to investigate the action to estrogen and its receptor with HPV in the progression of cervical lesions.
     [目的 ]研究在 17- β -E2 作用下正常宫颈上皮永生化细胞End1/E6E7的生长增殖和HPV16 /E6E7基因、ERβ表达的变化 ,探讨雌激素及HPV与ERβ在宫颈上皮病变发展过程中的作用。
短句来源
     Objective:To study the value of thin prep liquid-based cytology test(TCT),high-risk human papillomavirus (HPV-DNA) testing and colposcopy with biopsy in the early diagnosis of cervical lesions.
     目的:评价膜式液基薄层细胞学技术(thin prep liquid-based cytology test,TCT)、高危型人乳头状瘤病毒(high-risk human papillomavirus,HR-HPV)检测及阴道镜下宫颈活检对宫颈早期病变的诊断价值。
短句来源
     632 cases were infected with HPV of which benign cervical lesions accounted for 64% and cervical evasive cancer accounted for 90%.
     HPV感染阳性632例,其中宫颈上皮内瘤样变HPV感染率为64%,宫颈浸润癌HPV感染率为90%。
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  cervical lesions
Serum samples from 38 healthy women and 55 women with different types of cervical lesions were investigated for the presence of antibodies to Ras and against E4 and E7 proteins of human papillomavirus type 16 (HPV-16).
      
Using a semi-quantitative polymerase chain reaction technique (PCR) operated with carefully regulated sensitivity we have established two distinct levels of HPV 16 DNA which distinguish between high and low grade cervical lesions.
      
Definition of human papillomavirus type 16 DNA levels in low and high grade cervical lesions by a simple polymerase chain reacti
      
These data suggest that chromosome 1 may be considered as a marker chromosome for pre-malignant cervical lesions and that the DNA content measurements are complementary to the FISH results.
      
The effect of folate status may be restricted to early preneoplastic cervical lesions and not to more advanced disease.
      
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From Sept. 1979 to Dec. 1982 2000 cases of cervical lesion were examined by colposcopy. A series of 14 cases of cervical er.dometriosis following coagulation therapy are presented. The main complaints of these patients were vaginal bleeding, postcoital bleeding or bloody discharge which occurred 1-4 years after coagulation therapy. Congested plaques, spots or lines in red color situated around the cervical os were found in 11 cases. Small or medium size follicles of blue or brown color with...

From Sept. 1979 to Dec. 1982 2000 cases of cervical lesion were examined by colposcopy. A series of 14 cases of cervical er.dometriosis following coagulation therapy are presented. The main complaints of these patients were vaginal bleeding, postcoital bleeding or bloody discharge which occurred 1-4 years after coagulation therapy. Congested plaques, spots or lines in red color situated around the cervical os were found in 11 cases. Small or medium size follicles of blue or brown color with or without red plaques or lines were revealed in. 4 cases. Ten of these images were situated on the normal squamous epithelium, other four within the transformation zone. Cytologic correlations with Papanicolaou's smear were class I in 13 cases and classⅡ in 1.Six of these were biopsied, endometrial tissues were revealed in 4. Pathogenesis, clinical manifestations, colposcopical appearances, biopsy findings, treatments and prophylaxis of the disease were described and discussed.

本文报道了2000例阴道镜检查中的子宫颈子宫内膜异位症14例;其中活体组织检查者6例,4例病理切片中能见到子宫内膜腺体或间质。对其发生、临床表现、阴道镜图象、活体组织检查阳性率及防治等进行了分析和讨论。

From 1976 to 1985, 805 cases of chronic cervical lesion were treated with CO_2 laser. The cure rate was 96.1% with 700 cervical erosions, 98.2% with 57 chronic cervicitis, 92.3% with 13 hyperplastic cervical polyps and 100% with both 30 neoplasms and 5 dysplasia of the cervical squamous epithelium.

自1976~1985年应用二氧化碳激光治疗慢性宫颈疾病805例。其中宫颈糜烂700例,治愈率96.1%。慢性宫颈炎57例,治愈率98.2%。宫颈息肉样增殖13例,治愈率92.3%。宫颈赘生物30例及宫颈鳞状上皮非典型增生5例,治愈率100%,总有效率为100%。平均治愈时间为4.5周。激光疗法是利用其光热效应,使大部分组织气化,故坏死带很浅,治愈时间相应缩短。术中无痛苦,治疗彻底,复发率低,并发症少。

A series of clinical cervical lesions were studied for " the pres-ence of Human papibna virus (HPV) and Herpes simplex Viru.v type-2 (Hsv-2) antigens us- ing high specificity peroxidase -antperoxidase (PAP) method, and the correlation of viral antigens with koilocyte was analysed. It was shown that the positive rates of HRV and HSV-2 antigens in gervicitis cervical dysplasia and cervical cancer were 0, 41 .2%;31.3%,50 . 0 %; 2.1%. 62.8% , respectively; both HPV antigens and HSV-2 antigens were...

A series of clinical cervical lesions were studied for " the pres-ence of Human papibna virus (HPV) and Herpes simplex Viru.v type-2 (Hsv-2) antigens us- ing high specificity peroxidase -antperoxidase (PAP) method, and the correlation of viral antigens with koilocyte was analysed. It was shown that the positive rates of HRV and HSV-2 antigens in gervicitis cervical dysplasia and cervical cancer were 0, 41 .2%;31.3%,50 . 0 %; 2.1%. 62.8% , respectively; both HPV antigens and HSV-2 antigens were detected only in 2 dysplasia and 1 cervical cancer. Koilocyte were found in 72.2% dysplasia and 16.4% ca-ncer; HPV antigens were detected only in 4 / 11 koioctepositive dysplasia. and HSV-2 antigens were also, detected,in 6/12. kioyocyte-positive dysplasia. The results indiclte that HPV and HSV-2 may all associated with cervical cancer; koilocyte as a major characteristic for the diagnosis of HPV infection was worthwhile suspect.

通过特异性强的酶免疫PAP杂色方法,我们对一系列临床宫颈疾患中人乳头瘤病毒(HPV)和疱疹病毒Ⅱ型(HSV—2)抗原进行了检测,并分析了空泡细胞与抗原检出率的关系:结果表明,慢性宫颈炎、宫颈不典型增生和浸润性宫颈癌中HPV和HSV—2抗原的检出率分别为:0,41.2%;31.3%,50.0%;2.1%,62.8%;仅有两例不典型增生和1例浸润性宫颈癌中同时测到两种病毒的抗原。空泡细胞(Koilocyte)的阳性率在慢性炎症为0,不典型增生为72.2%,浸润性癌为16.4%;11例空泡细胞阳性的不典型增生中有4例测到了HPV抗原,但12例空泡细胞阳性的不典型增生中也有6例HSV—2抗原阳性。实验结果提示,宫颈癌的病毒病因:HSV—2和HPV可能均与官颈癌的发生有关,空泡细胞做为诊断HPV感染的特征性标志,值得怀疑。

 
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