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mice
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  小鼠
    Polychlorinated Biphenyls (Aroclor 1254) on Reproductive Toxicology in Mice
    Aroclor 1254对小鼠生殖毒理的研究
短句来源
    Expression of Green Fluorescent Protein (GFP) Fused Gene in Preimplantation Embryos of Mice
    绿色荧光蛋白融合基因在小鼠早期胚胎表达的研究
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    Expression of the Multiepitope Peptide of GP4 and GP5 of PRRSV and Its Immune Response Elicited in Mice
    PRRSV GP4和GP5多表位串联基因的表达及在小鼠诱导的免疫反应
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    Study on Molecular Pathology of Hepatocelluar Carcinoma in P21~(HBsAg/HBsAg) Transgenic Mice
    p21~(HBsAg/HBsAg)转基因小鼠发生肝细胞癌的分子病理学研究
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    THE IMMUNE STATUS OF TUMOR-BEARING HOST——Ⅰ. OBSERVATIONS ON THE DYNAMICS OP THE SPLEEN HAEMOLYTIC PLAQUE-FORMING CELLS IN SEVERAL STRAINS OF TUMOR-BEARING MICE
    肿瘤宿主的免疫状态——Ⅰ.几种带瘤小鼠脾脏溶血空斑形成细胞的动态观察
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    THE BREEDING AND QUALITY CONTROL OF NUDE (THYMUS DEFICIENT) MICE
    无胸腺小(裸)的繁殖及质量控制
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    Studies on the Infection of NPV82-17 Strain of Nuclear Polyhedrosis Virus from Mamastra brassicae (Lepidoptera) to Nude Mice
    甘兰夜蛾核型多角体82—17病毒株对裸感染性的研究
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    A DIRECT ENZYME - LINKED IMMUNOSORBENT ASSAY FOR THE DETECTION OF PSUEDORABIES VIRUS ANTIGEN IN MICE
    固相微球直接ELISA检测小白病理组织中PRV抗原
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    Studies on the Polymorphism of the Protein and Isoenzymes in KM (Kunming) Mice
    中国昆明蛋白质及同工酶多态性的研究
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    Studies of Growth Rregularity in Kun Ming Mice(2)
    昆明种小白生长发育规律的研究(二)——乳腺的生长发育
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  “mice”译为未确定词的双语例句
    Expression of Toxoplasma Gondii Gene ROP2 in E.coli and BCG and Its Immunogenicity on Mice
    弓形虫ROP2基因在大肠杆菌和卡介苗中的表达及免疫原性的研究
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    Immune Efficacy Evaluation of a Recombinant Pseudorabies Virus Expressing HA of H3N2 Swine Influenza Virus in Mice and Pigs
    表达H3N2亚型猪流感病毒HA的重组伪狂犬病病毒免疫效力的评价
短句来源
    So the results of our experiments showed ag85b、esat-6、hsp65、mpb64、ag85b-esat-6、hsp65-esat-6 and mpb64-esat-6 DNA vaccines were successfully constructed. They both induced antigen-specific humoral and cellular immune responses in BALB/c mice. So this experiment may be useful for the development of Bovis tuberculosis vaccine.
    成功构建了牛分枝杆菌ag85b、esat-6、hsp65、mpb64单基因和ag85b-esat-6、hsp65-esat-6、mpb64-esat-6双价融合基因DNA疫苗,从而为牛结核病新型疫苗的研制奠定了基础。
短句来源
    Western blot analysis showed that the expressed GP5m and M proteins had good biological activities analogy to the authentic proteins and could form disulfide-linked heterodimers GP5m/M in BHK-21 cells transfected with pCI-ORF5m/ORF6.Immunological responses to the constructs were investigated in BALB/c mice and piglets.
    转染BHK-21细胞,Western blot检测证实ORF5m和ORF6基因均获得正确表达,并且共表达的GP5m和M蛋白能够形成异源二聚体。
短句来源
    Methods:The GP5 protein gene was amplified with PCR and cloned into both pCMV-Ub containing mice ubiquitin gene and pCMV plasmid,respectively,and two recombinant plasmids,pCMV- Ub-GP5 and pCMV-GP5,were constructed and identified.
    方法:本研究将ORF5 DNA片段克隆到含泛素(Ub)基因的表达载体pCMV-Ub和pCMV载体,构建成重组质粒pCMV-Ub-GP5和pCMV-GP5。
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  mice
Investigations of their biodistribution in mice showed all five pseudo-peptide chelators (MGQ, MGGQ, MAGQ, MVGQ, MFGQ) are rapidly cleared from blood, mainly through renal clearance.
      
The multiple antioxidant activity of the polysaccharides was evidenced by significant reducing power, superoxide scavenging ability, inhibition of mice erythrocyte hemolysis mediated by peroxyl free radicals, and also ferrous ion chelating potency.
      
Compounds Ia-Ih were hydrogenated with Pd-C to give IIa-IIh, and their hypoglycemic activity was evaluated with a glucose oxidase kit and insulin load test on normal mice.
      
The purified product was found to be biologically active and to reduce the food intake and body weight of mice during tests.
      
The effects of hematopoietic stem/progenitor cells (HSPCs) expanded in the two step coculture with human bone marrow mesenchymal stem cells (hMSCs) on the hematopoietic reconstruction of irradiated NOD/SCID mice were studied.
      
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(1) A Strain of Trypanosoma equiperdum was made resistant to by repeated administration of subcurative doses to infected mice in a series of passages.The resistance was found to have increased 40 times after 32 passages in mice by blood inoculation. (2) In subsequent passages without simultaneous administration of the drug, the resistant strain had lost its resistance very rapidly, but a trace of resistance still remained for at least 57 passages in mice, after which time the passage was discontinued....

(1) A Strain of Trypanosoma equiperdum was made resistant to by repeated administration of subcurative doses to infected mice in a series of passages.The resistance was found to have increased 40 times after 32 passages in mice by blood inoculation. (2) In subsequent passages without simultaneous administration of the drug, the resistant strain had lost its resistance very rapidly, but a trace of resistance still remained for at least 57 passages in mice, after which time the passage was discontinued. (3) When mice infected with the resistant strain were treated with curative doses of, Atrycide, Trypanol and Tryparsamide, it was found that the resistant strain of this trypanosome had no cross resistance to the drugs tested.

(1)马媾疫锥虫用逐步提高之纳格宁药量在小白鼠体内连续传代,可以逐渐产生抗药性,在32代以后其耐受药量可增高至40倍。在停止用药后继续传代,则此种抗药性消失很快,但仍保留残余之抗药性,在传代57代仍不见消失。 (2)马媾疫锥虫在小白鼠体内获得纳格宁抗药性之后,对于、Antrycide、Trypanol及Tryparsamide均无交互抗药性之发生。

The present paper is concerned with the toxicity of dapterex to certain species of experimental and domestic animals.The results are as follows: 1.The LD_(50) of dipterex given by intraperitoneal injection and oral administration to albino mice are shown to be 450 and 660mg/kg respectively.Same susceptibility to the drug is found in male and female.Exposed 42 days,the aqueous preparation manifests a marked increase in its toxicity. 2.Single intraperitoneal injection of atropine (10mg/kg); concomitant intraperitoneal...

The present paper is concerned with the toxicity of dapterex to certain species of experimental and domestic animals.The results are as follows: 1.The LD_(50) of dipterex given by intraperitoneal injection and oral administration to albino mice are shown to be 450 and 660mg/kg respectively.Same susceptibility to the drug is found in male and female.Exposed 42 days,the aqueous preparation manifests a marked increase in its toxicity. 2.Single intraperitoneal injection of atropine (10mg/kg); concomitant intraperitoneal injection of atropine (10mg/kg) and PAM (50mg/kg); atropine and coramine (120mg/kg); and atropine and corazol (30mg/kg) manifest a marked protective effect on mice against intoxication by dipterex.The acute LD_(50) of the drug has to be increased from 450 to 618,1,300,1,312 and 1,217mg/kg respectively. 3.It is found that chickens and ducks are very susceptible to dipterex.The LD_(50) by oral administration are 46.6 and 44.8mg/kg respectively.The absolute lethal dose for cats after intraperitoneal injection is 300mg/kg.The toxic doses of dipterex by oral administration for pigs,sheep,cattle and horses are 65,200,100 and 50mg/kg respectively; 50mg/kg for pigs and 65mg/kg for sheep by intramuscular injection.The toxic effect of dipterex is primarily shown in the digestive system after oral administration.Intramuscular injection of dipterex to sheep produces very marked symptoms of respiratory system and local irritation. 4.Considering the anthelmintic efficiency and safety,it is preferrable to a minister dipterex by oral rather than parenteral.Recommended doses by oral are 100mg/kg for pigs and sheep,50-100mg/kg for cattle and 30mg/kg for horses.

一、国产敌百虫对小白鼠腹腔注射的LD_(50)剂量为450mg/kg,口服LD_(50)剂量为660mg/kg。雌雄小白鼠对敌百虫毒性的敏感性,无性别差异。敌百虫水溶液在室溫下貯放42天后,毒性明显增加。二、硫酸阿託品10mg/kg,PAM50mg/kg+阿託品10mg/kg,尼可他米120mg/kg+阿託品10mg/kg,五甲烯四氮唑30mg/kg+阿託晶10mg/kg对接受中毒量敌百虫的小白鼠,均有明显的保护作用,它們能分別将敌百虫的急性LD_(50)剂量提高到618、1300、1312和1217mg/kg。三、鸡、鴨对敌百虫的毒性非常敏感,口服LD_(50)剂量分別为46.6和44.8 mg/kg。猫腹胜注射的絕对致死量为300mg/kg。各种家畜口服敌百虫的中毒量为:猪65、羊200、牛100、馬50mg/kg;肌肉注射的中毒量为:猪50、羊65mg/kg。口服敌百虫的毒性反应,主要表現于消化系統。肌肉注射敌百虫,在羊呼吸系統和注射局部的反应甚为强烈。四、根据驅虫功效和反应程度,作者建議口服比注射給药安全,推荐的口服驅虫剂量为,猪100mg/kg,羊100mg/kg,牛50—100mg/kg,馬30m...

一、国产敌百虫对小白鼠腹腔注射的LD_(50)剂量为450mg/kg,口服LD_(50)剂量为660mg/kg。雌雄小白鼠对敌百虫毒性的敏感性,无性别差异。敌百虫水溶液在室溫下貯放42天后,毒性明显增加。二、硫酸阿託品10mg/kg,PAM50mg/kg+阿託品10mg/kg,尼可他米120mg/kg+阿託品10mg/kg,五甲烯四氮唑30mg/kg+阿託晶10mg/kg对接受中毒量敌百虫的小白鼠,均有明显的保护作用,它們能分別将敌百虫的急性LD_(50)剂量提高到618、1300、1312和1217mg/kg。三、鸡、鴨对敌百虫的毒性非常敏感,口服LD_(50)剂量分別为46.6和44.8 mg/kg。猫腹胜注射的絕对致死量为300mg/kg。各种家畜口服敌百虫的中毒量为:猪65、羊200、牛100、馬50mg/kg;肌肉注射的中毒量为:猪50、羊65mg/kg。口服敌百虫的毒性反应,主要表現于消化系統。肌肉注射敌百虫,在羊呼吸系統和注射局部的反应甚为强烈。四、根据驅虫功效和反应程度,作者建議口服比注射給药安全,推荐的口服驅虫剂量为,猪100mg/kg,羊100mg/kg,牛50—100mg/kg,馬30mg/kg。五、敌百虫的驅虫作用量对蠕虫直接发生作用,并非由于增强宿主的腸道蠕动所致。

Summary In order to find a simple and rapid method for evaluation of swine erysipelas serum, the hemagglutination-inhibition test was tried and the successful results may be briefly summarized as follows: (1) Among more than one hundred strains of Erysipelothrix rhusiopathiae under test, a particular strain, E. 5601, was found to agglutinate chicken erythrocytes more clearly than others in the same way as described for influenza virus. (2) The agglutinating action of strain E. 5601 was specifically inhibited...

Summary In order to find a simple and rapid method for evaluation of swine erysipelas serum, the hemagglutination-inhibition test was tried and the successful results may be briefly summarized as follows: (1) Among more than one hundred strains of Erysipelothrix rhusiopathiae under test, a particular strain, E. 5601, was found to agglutinate chicken erythrocytes more clearly than others in the same way as described for influenza virus. (2) The agglutinating action of strain E. 5601 was specifically inhibited by swine erysipelas immune sera, and was not influenced by normal serum, hog-cholera serum, nor by hemorrhagic septicemia (or pasteurellosis) sera. (3) Thirteen batches of swine erysipelas hyper-immune sera were detected for their potency, and, as a result, it was found that the hemagglutination-inhibition titers of different batches showed a series of gradient degrees in which potent sera always possessed an inhibition titer above 1: 384, impotent ones usually below 1:192 or less, and normal serum or sera other than swine erysipelas almost no titer. This fact was confirmed by a series of correlated biological tests with mice. (4) By using this method and trying to get ready all those necessary materials and equipments on hand, the potency of swine erysipelas hyper-immune sera can be evaluated within on hour.

一、通过猪丹毒杆菌有与鸡血球凝集的特性,笔者自100多个猪丹毒杆菌品系內找出了凝集作用良好的猪丹毒杆菌E、5601品系,并用来供制本試驗的抗原。二、本試驗用的抗猪丹毒免疫血清共有13个批号,并以健馬血清、抗出敗血清等四种血清作了对照試驗。試驗結果,各个抗丹毒免疫血清的凝集抑制价高低表現不一,有凝集抑制价甚低者,有高达1:384者。一般在有效期內的抗猪丹毒免疫血清,其凝集抑制价最高;失效或距失效期較久的血清則凝集抑制价逐漸减低。至健馬血清、抗禽畜出敗血清等非特异性血清均无凝集抑制現象。三、小白鼠作血清效力对照試驗說明:鸡血球凝集抑制价的高低与抗猪丹毒血清的免疫效力有直接的密切关系,經以13批抗猪丹毒血清几次重复試驗証明,无凝集抑制价的各类血清或者凝集抑制价低于1:192者的抗猪丹毒血清,对小白鼠的保护力亦差;若凝集抑制价能达1:384者,則血清效力佳良,并可符合国家頒布的效力标准要求合格适用。四、本报告內就猪丹毒免疫血清鸡血球凝集抑制試驗的操作方法以及在猪丹毒免疫血清生产上和血清效力鑑定上的实用价值,均經加以叙述与闡明。

 
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