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mice
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  小鼠
    Study of Esculentoside A on Autoimmunity in Mice and Its Molecular Mechanisms
    商陆皂苷甲对自身免疫性小鼠及其分子机制的研究
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    The Research of ZIDIANKELI to the Mechanism of the Immunoregulation of the ITP Model Mice
    紫癜颗粒对ITP模型小鼠免疫调控的机理研究
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    The Study on the Mechanism of Antiviral Effects and Regulating Immunoinjury and Apoptosis of Myocardium by Scutellaria Baicalin in CVB3m Myocarditis Mice
    黄芩甙抗CVB_(3m)和调控CVB_(3m)感染小鼠心肌免疫损伤及细胞凋亡的实验研究
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    Effects of XingNaoQiZhi Capsule and Its Drug-containing Serum on Repeated Ischemia-Reperfusion Mice and PC12 Cells
    醒脑启智胶囊及药物血清对反复脑缺血再灌注小鼠及嗜铬细胞瘤PC12细胞的影响
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    Decoction on Hematopoietic Cells in Mice
    八珍汤对小鼠造血功能影响的机制研究
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    A PRELIMINARY STUDY ON PREVENTION AND THERAPEUTIC EFFECTS OF BOVINE THYMOSIN F_5 ON ACUTE RADIATION SICKNESS OF MICE
    小牛胸腺素F_5对小白急性放射病防治效果的初步观察
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    EFFECT OF THYMoSIN(F_5) ON CAMP OF PERITONEAL EXUDATE MACROPHAGES IN MICE
    猪胸腺素(F_5)对小白腹腔渗出液巨噬细胞cAMP含量的影响
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    A STUDY OF THE DISTRIBUTION OF SCHISTOSOMICIDAL DRUG-~3H-7505 IN MICE
    ~3H-“7505”在小白体内分布的研究
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    EFFECT OF BU GU ZHI INJECTION(补骨脂注射剂)ON HISTOLOGY AND HISTOCHEMISTRY OF LIVER IN HYDROCORTICOID MICE
    补骨脂注射剂对小白氢化考的松模型肝组织的组织学与组织化学研究
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    ZINC AND PROTEIN PROMOTE GROWTH IN YOUNG MICE
    锌与蛋白质对促进幼龄小白生长的复合作用
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  “mice”译为未确定词的双语例句
    Distribution and Excretion of ~3H-Rhomotoxin in Mice
    ~3H-八厘麻毒素的分布和排泄
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    The Influence of Exogenous Interleukin-2 on the in Vivo Immune Reactivity in Mice
    外源性IL-2对体内免疫反应的影响
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    THE EFFECT OF ALLOXAN INDUCED DIABETES ON CFU-GM OF MICE
    四氧嘧啶所致的糖尿病对大鼠CFU-GM产率的影响
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    Studies on Polysaccharides from Algae——Ⅰ.The Antitumor Activity of Polysaccharides of Sargassum Thunbegii on S180 in Mice and their Effect of Superoxide Dismutase
    海藻多糖的实验研究 Ⅰ.鼠尾藻多糖对肉瘤S_(180)的抑制和超氧化物歧化酶的影响
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    THE EFFECTS OF SODIUM SALT OF 3,7-BISHEMISUCCINATE OF 7-HYDROXYCHOLESTEROL (RS 034) ON DNA, RNA AND PROTEIN SYNTHESES IN BONE MARROW CELLS, LIVER AND SPLEEN IN MICE BEARING EAC AND ON HEMOGRAM IN RATS
    7β-羟基胆固醇双琥珀酸单酯钠(RS 034)对荷瘤小鼠骨髓细胞、肝、脾的DNA、RNA和蛋白质合成及对大鼠血象的影响
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  mice
Investigations of their biodistribution in mice showed all five pseudo-peptide chelators (MGQ, MGGQ, MAGQ, MVGQ, MFGQ) are rapidly cleared from blood, mainly through renal clearance.
      
The multiple antioxidant activity of the polysaccharides was evidenced by significant reducing power, superoxide scavenging ability, inhibition of mice erythrocyte hemolysis mediated by peroxyl free radicals, and also ferrous ion chelating potency.
      
Compounds Ia-Ih were hydrogenated with Pd-C to give IIa-IIh, and their hypoglycemic activity was evaluated with a glucose oxidase kit and insulin load test on normal mice.
      
The purified product was found to be biologically active and to reduce the food intake and body weight of mice during tests.
      
The effects of hematopoietic stem/progenitor cells (HSPCs) expanded in the two step coculture with human bone marrow mesenchymal stem cells (hMSCs) on the hematopoietic reconstruction of irradiated NOD/SCID mice were studied.
      
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A new method for the biological assay of vegetable purgatives based on the numbers of wet faeces excreted by groups of mice after dosing is described. The relation of the number of wet faeces per group of mice to the logarithm of the dose was found to be linear. A cage has been specially designed for this assay and it has been found advantageous to incorporate a definite proportion of water in the diet during test. 40 mice divided equally into 4 groups were used in each assay. 2 groups received...

A new method for the biological assay of vegetable purgatives based on the numbers of wet faeces excreted by groups of mice after dosing is described. The relation of the number of wet faeces per group of mice to the logarithm of the dose was found to be linear. A cage has been specially designed for this assay and it has been found advantageous to incorporate a definite proportion of water in the diet during test. 40 mice divided equally into 4 groups were used in each assay. 2 groups received the standard preparation and the other 2 groups received the test preparation. The standard deviation of a single determination based on 9 such assays was estimated to be 15.7 per cent. For rhubarb and its preparations, a“6-point”assay is advocated. With suitable restric-tion in the design of the assay, it is possible to calculate the potency by simple methods. Powdered crude drugs are used as laboratory standards in the assay of senna and rhubarb. The doses of cascara bark required to produce distinctive responses are too inconveniently large to be administered in suspension. It was found possible to use a potent extract of cascara in place of the powdered bark as a laboratory standard. Examples of the assay and the subsequent calculations are given. The method described is not only convenient in use but also gives a comparatively high degree of accuracy. The method has been successfully applied to senna leaf, senna fruit, rhubarb, cascara sagrada and extracts and commercial preparations made from these drugs, pure glycosides(sennosides A and B) and pure anthracene compounds(aloe emodin and aloe-emodine anthranol).

(1)本文详述植物性泻药的一种新的生物测定法,此法係用小白鼠在服药后所排出的濕粪数为基础,以定泻药的效价。(2)小白鼠服药後所排出的湿粪数与剂量指数的关係经证明为一直线。(3)本法所用鼠笼係特别设计,并证明在饲料内加入一定量的饮水,具有多种优点。(4)番泻效价的测定,每次用小白鼠4组,每组10只。2组给与标准品,另外2组给与试验品。根据9次试验的结果,试验的标准差是15.7%.(5)大黄效价的测定,以采用“6点”法为宜,即每次试验用小白鼠6组,3组给与标准品,另外3组给与试验品,所得的准确度与上述相仿。波希鼠李皮浸膏的效价测定,则用“4点”法或“6点”法均可。(6)所有试验一律采用粉状生药为实验室的比较标准,但是波希鼠李皮的效价太低,它的粉末不适於作为标准之用,可用波希鼠李皮乾浸膏来代替,作为比较标准。(7)本文对於效价测定及其计算方法都举例说明,并介绍了比较常法为简捷的相关效价计算法。(8)本法不但方便易行,而且有相当高的准确度;曾用在番泻、大黄、波希鼠李皮及其制剂,以及一些纯粹的蒽醌衍生物的效价测定,都获得了满意的结果。

1.Twenty-two agents were tested in vitro, and four of them also in vivo for their antituber- culous activity. 2.Ginkgolic.acid,the active principle of ginkgo fruit against tubercle bacilli,was found to exist only in the fleshy part(endocarp)of the fruit.The tuberculostatic action of ginkgolic acid in vitro was not influenced by heating,but the presence of serum raised the minimal effec- tive concentration from 1:400,000 to 1:1000.The results of in vivo tests failed to demonstrate any effect of the different...

1.Twenty-two agents were tested in vitro, and four of them also in vivo for their antituber- culous activity. 2.Ginkgolic.acid,the active principle of ginkgo fruit against tubercle bacilli,was found to exist only in the fleshy part(endocarp)of the fruit.The tuberculostatic action of ginkgolic acid in vitro was not influenced by heating,but the presence of serum raised the minimal effec- tive concentration from 1:400,000 to 1:1000.The results of in vivo tests failed to demonstrate any effect of the different parts of ginkgo fruit in- cluding ginkgolic acid on the experimental tuber- culosis of mice.No apparent difference was found between the activity of ginkgo fruit with or without previous preparation with vegetable oil. 3.(?)In vitro,garlic exhibited rather weak tuberculostatic action,which decreased slightly in thè presence of serum.The in vitro effect of the winter garlic was better than that of the spring one.No curative effect was exerted by garlic on the experimental tuberculosis of mice. 4.The minimal tuberculostatic concentra- tion of berberine in vitro was found to be around 1:4000,and the èffect slightly decreased in the presence of serum.The development of experi- mental tuberculosis of mice was delayed by the administration of berberine sulfate in daily oral doses of 1.5—2.5 gm./kg. 5.There was definite curative effect of stepharanthine on the experimental tuberculosis of mice in daily doses of 200 mg./kg.;significant toxicity appeared,however,at that dosage level. 6.No significant tuberculostatic effect in vitro was found among other crude drugs. 7.“Hei pao”was ineffective in vitro,while citrinin was definitely effective and its minimal tuberculostatic concentration determined as 1:20.000. 8.Amon synthetic compounds tested,the in vitro tuberculostatic potency of an isomer of PAS was only one-hundredth of that of sodium para- amino-salicylate.The tuberculostatic effects of four sulfones were not satisfactory.The minimal tuberculostatic concentration in vitro of syn- thotic compound Ⅵ was 1:200,000. 9.It was found that the effectlve ranges of the concentration and dosage of thiosemicarba- sone in viro and in vivo were very broad,and the lower margins were comparable with those of isonicotinyl hydrazine.These facts may explain the elinieal effectiveness of thiosemicarbazone used in small doses.

1.在玻器内试验了22种药物,在动物体内试验了四种药物的抗结核杆菌作用。2.白果的抗结核杆菌有效成分(白果酸)仅存在于白果果浆中。白果酸在玻器内的抗菌作用不受加热的影响;但血清能使其最低有效浓度从1:400,000跃至1:1000。白果各部分及白果酸对小鼠的实验结核症并无肯定的疗效。油浸过的白果与未浸过的作用并无显著不同。3.大蒜在玻器内具有较弱的抗结核杆菌作用,遇血清则效力略减;冬季大蒜比春季大蒜的效力高。对小鼠的实验结核症并无疗效。4.黄连硷在玻器内的最低抑制结核杆菌浓度是1:4000左右,遇血清则效力略减。每日食入硫酸黄连硷约1.5—2.5克/公斤时,可以延缓小鼠实验结核症的发展。5.使他肺安定每日200毫克/公斤时,对小鼠实验结核症有肯定的疗效,但已表现相当大的毒性。香豆素在玻器内当浓度为1:2000时有部分抗结核杆菌作用。6.其他生药中,仅韭菜及青蒜在修改的都氏培养基中具有微弱的抗结核杆菌能力,但在尤氏培养基中无效。7.海宝在玻器内无效,橘霉素的最低制菌浓度是1:20,000。8.所试的化学合成品中,对氨水杨酸的同质异构物的抗结核杆菌作用仅为对氨水杨酸钠的1/100。砜类化合物的抗结核杆菌作用很微弱...

1.在玻器内试验了22种药物,在动物体内试验了四种药物的抗结核杆菌作用。2.白果的抗结核杆菌有效成分(白果酸)仅存在于白果果浆中。白果酸在玻器内的抗菌作用不受加热的影响;但血清能使其最低有效浓度从1:400,000跃至1:1000。白果各部分及白果酸对小鼠的实验结核症并无肯定的疗效。油浸过的白果与未浸过的作用并无显著不同。3.大蒜在玻器内具有较弱的抗结核杆菌作用,遇血清则效力略减;冬季大蒜比春季大蒜的效力高。对小鼠的实验结核症并无疗效。4.黄连硷在玻器内的最低抑制结核杆菌浓度是1:4000左右,遇血清则效力略减。每日食入硫酸黄连硷约1.5—2.5克/公斤时,可以延缓小鼠实验结核症的发展。5.使他肺安定每日200毫克/公斤时,对小鼠实验结核症有肯定的疗效,但已表现相当大的毒性。香豆素在玻器内当浓度为1:2000时有部分抗结核杆菌作用。6.其他生药中,仅韭菜及青蒜在修改的都氏培养基中具有微弱的抗结核杆菌能力,但在尤氏培养基中无效。7.海宝在玻器内无效,橘霉素的最低制菌浓度是1:20,000。8.所试的化学合成品中,对氨水杨酸的同质异构物的抗结核杆菌作用仅为对氨水杨酸钠的1/100。砜类化合物的抗结核杆菌作用很微弱。合成品〔Ⅵ〕的最低制菌浓度是1:200,000。9.硫脲胺的部分制菌浓度范围和其对小鼠实验结核症有效剂量的范围都很广,可以追及异烟肼的水平,这可解释临床上其剂量很小,但仍能生效的原因。

The extract of Lu-jung(growing horns from Cervus xanthopygus,Milne-Edwards)given to castrated rats or mice could not promote the growth of their prostates and seminal vesicles.It showed no estrogenic activity in ovariectomized mice.While tested on gonadotropic activity,it could neither induce the formation of blood spots in ovaries of non-pregnant rabbits,nor cause toads to release spermatozoa into their urine.

1.马鹿鹿茸的浸液经去睾丸大白鼠和小白鼠前列腺精囊称重法和去卵巢小白鼠阴道涂片法试验,证明并无雄性素或雌性素样作用.2.马鹿鹿茸的浸液并不能使未孕家兔的卵巢出现血斑,也不能促使雄蟾蜍排精,因此亦不具有向性腺激素样作用.

 
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