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hla genes
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  hla基因
     HLA genes locate in human chromosome 6p21.3 region. HLA class I gene spans approximately 1500 kb, encoding transplanting antigen.
     HLA基因位于人类第6号染色体短臂6p21.3区域,其中HLA-Ⅰ类基因区靠近染色体顶端,长约1500kb,编码移植抗原。
短句来源
     HLA genes locate in human chromosome 6p21. 3 region. HLA class I gene spans approximately 1500 kb, encoding transplantation antigen.
     HLA基因位于人类染色体6p21.3区域,其中HLA-Ⅰ类基因区靠近染色体顶端,长约1500kb,编码移植抗原。
短句来源
     Study on the Correlation between Acute Lymphoblastic Leukemia and HLA genes in Southern China Han population
     中国南方汉族急性淋巴细胞白血病与HLA基因相关性研究
短句来源
     Research advance of HLA genes in diffuse panbronchiolitis
     弥漫性泛细支气管炎HLA基因的研究进展
短句来源
     HLA genes play a key role in immune-response to heterogenetic and allogeneic antigens in the inflammatory tissues.
     HLA基因在调节机体对抗原的免疫应答反应方面起重要作用,因此,研究HLA与大动脉炎患者的相关性对揭示大动脉炎的发病机制具有重要意义。
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  “hla genes”译为未确定词的双语例句
     Objectives: We choosed 30 patients with idiopathic nephrotic syndromes(INS)of Han Population of people in Shanxi and 45 healthy people in order to access the association of HLA-A、B、DR gene polymorphism with,to look for susceptible HLA genes to INS’s patients and the HLA gene frequency in INS’s patients, and to investigate the etiopathogenisis and pathogenesis of INS.
     目的:为了了解HLA-A、B、DR位点的基因多态性与原发性肾病综合征的联系关系,寻找原发性肾病综合征的HLA的易感基因及山西省部分原发性肾病综合征患者出现的基因频率的变化规律,研究原发性肾病综合征患者的病因及致病机理,我们选取了山西汉族30例原发性肾病综合征患者及45例汉族健康人的DNA进行了研究。
短句来源
     HLA genes on human chromosome 6 code for the major histocompatibility complex (MHC) proteins that are important in presentation of antigens and self recognition by immune cells.
     HLA复合体位于人类6号染色体短臂上,其基因功能多与免疫反应有关。 研究发现HLA与许多自身免疫性疾病相关,了解HLA与斑秃的相关性有助于揭示本病的发病机理。
短句来源
     However, most of studies focused on the correlation of type II genes and cervical cancer due to the effective application of HLA gene typing technique and relatively little work has been performed to identify the possible correlation of HLA genes and cervical cancer.
     虽然以往的报道主要集中于HLA-Ⅱ类基因与宫颈癌的关联,但是我们认为HLA-Ⅰ类分子对病毒抗原、肿瘤抗原等内源性抗原提呈具有重要意义,因此系统地研究HLA-Ⅰ类功能基因,包括对HLA-Ⅰ类等位基因型的分析,对明确HLA宫颈癌易感性的关系可能是一条捷径和突破口。
短句来源
     PCR amplification of HLA genes followed by electrophoresis and its application in bone marrow transplantation
     HLA 基因序列电泳多态性分析及其在骨髓移植中的应用
短句来源
     This program presented here aims at typing HLA genes systematically among 166 unrelated Han's patients withPV from Anhui province using by PCR-SSP (sequence-specific primers) and PCR-RFLP (restriction fragment length polymorphism) techniques.
     本课题采用PCRsSP(sequence-specific primers,序fd特异性弓物)和 PCR-RFLP
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  相似匹配句对
     Research advance of HLA genes in diffuse panbronchiolitis
     弥漫性泛细支气管炎HLA基因的研究进展
短句来源
     Association of HLA-DRB1 genes with pulmonary tuberculosis
     人类白细胞抗原DRB1基因与肺结核的相关性研究
短句来源
     HLA AND CHOLELITHIASIS
     HLA抗原与胆石症关联研究
短句来源
     HLA Summarize
     HLA系统实施技术的研究
短句来源
     RADIOSENSITIVITY AND GENES
     辐射敏感性和基因
短句来源
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  hla genes
Examination of populations living in regions of fallout radiation revealed changes in the distribution of HLA genes not only in irradiated individuals, but also in their children and grandchildren.
      
Non-HLA genes and the susceptibility to insulin dependent diabetes: the role of the CTLA-4 gene
      
Polymorphisms of individual genes outside the MHC also contribute to diabetes risk but recent evidence suggests that there are additional non-HLA genes determining susceptibility linked to the MHC.
      
In 9 families of which at least two members were affected by rheumatoid arthritis (RA), no specific combination of HLA genes, i.e., HLA haplotype was found to be associated with transmission of disease susceptibility.
      
Further, homozygosity of a lethal gene which is in linkage disequilibrium with HLA genes may have a role in some unexplained fetal deaths.
      
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The genetic distance among 15 national minories (Zhuang, Yiao, Dong, Li, Mongolian, Hasake, Uysur, Jing, Qiang, Olunchun, Zhaoxian, Zang, Dongxiang) and 6 populations living in Hainan, Guangxi, Sichuang, Shanghai, Beijing, and Shenyang was computed with Nei's method (1978). The HLA gene frequency data were used. A phylogenetie tree of 21 populations was constructed on the basis of genetic distance with the unweighted pair-group method of clustering by Sneath and Sokal (1973).The results show that the phylogenetic...

The genetic distance among 15 national minories (Zhuang, Yiao, Dong, Li, Mongolian, Hasake, Uysur, Jing, Qiang, Olunchun, Zhaoxian, Zang, Dongxiang) and 6 populations living in Hainan, Guangxi, Sichuang, Shanghai, Beijing, and Shenyang was computed with Nei's method (1978). The HLA gene frequency data were used. A phylogenetie tree of 21 populations was constructed on the basis of genetic distance with the unweighted pair-group method of clustering by Sneath and Sokal (1973).The results show that the phylogenetic relationships revealed in this study agree fundamentally with the results from historical cad anthropological studies.

收集整理了国内壮、瑶、侗、苗、京、羌、鄂伦春、朝鲜、藏及东乡等15个少数民族和6个汉族群体的HLA基因频率资料,用Nei氏法计算出他们之间的遗传距离,并根据遗传距离按Sneath和Sokal氏聚类原则绘制出系统树。结果发现这些人群之间的遗传距离和系统树所表示的血缘关系与人类学家及历史学家研究的结果基本上一致。

It was reported here the correlation between constitution type in TCM of healthy subject and frequency distribution of HLA gene of Miao (苗) nation- ality in Hainan Island,110 items of body' trait investigated on 97 healthy subjects of Miao nationality in Hainan Island were analysed with the method of factor analysis by IBM-PC/XT microcomputer.The results showed that Yin dominating over Yang type (阴多阳少型),Yang dominating over Ying type (阳多阴少型) and Yin-Yang balance type (阴阳平衡型) were 32,61,6 cases respectively.From...

It was reported here the correlation between constitution type in TCM of healthy subject and frequency distribution of HLA gene of Miao (苗) nation- ality in Hainan Island,110 items of body' trait investigated on 97 healthy subjects of Miao nationality in Hainan Island were analysed with the method of factor analysis by IBM-PC/XT microcomputer.The results showed that Yin dominating over Yang type (阴多阳少型),Yang dominating over Ying type (阳多阴少型) and Yin-Yang balance type (阴阳平衡型) were 32,61,6 cases respectively.From this,constitutional type of TCM were drawn and verified.Factors Ⅰ-Ⅲ the constitutional indices drawn respectively by positive and negative variables conformed to the traits of constitutional types in TCM.Homologous Leucocytic Antigen(HLA) was measured in these subjects. The results showed that the frequency distribution of HLA gene among the constitutional types of Miao subjects in Hainan Island was:The frequency of A2 was much higher Yang dominating over Yin type but the frequency of B_5 was much higher in this same type of the Han (汉) subjects in Guang- dong.However,it should be further inuestigated.

用主因子分析法和 HLA 组织相容性试验,对海南岛苗族97例健康人的中医体质类型与 HLA 基因频率分布的关系进行研究。结果是:阳多阴少型61例,阴多阳少型32例,阴阳和平型6例;从体征指标的主因子分析中,发现Ⅰ—Ⅲ因子相对应的变量,与中医体质类型特征基本相符。本材料显示海南岛苗族健康人的 HLA-A,-B,-C 抗原分布的总趋势与其它资料基本相似,在中医体质类型中,阳多阴少型的 A2频率较高,与阴多阳少型相比,有显著性差异(P<0.01)。

It is well established that genetic and environmental factors are involved in the etiology of essential hypertension(EH). Previous studies have suggested that at least one of the HLA genes is responsible for the genetic susceptibility to EH. Our aim in the present study was to investigate this issue in China by the PCR-SSP HLA-DRB1 typing method. The results showed an increased frequency of HLA-DR2 and a decreased frequency of HLA-DR7 with EH patients compared with controls. We consider...

It is well established that genetic and environmental factors are involved in the etiology of essential hypertension(EH). Previous studies have suggested that at least one of the HLA genes is responsible for the genetic susceptibility to EH. Our aim in the present study was to investigate this issue in China by the PCR-SSP HLA-DRB1 typing method. The results showed an increased frequency of HLA-DR2 and a decreased frequency of HLA-DR7 with EH patients compared with controls. We consider that HLA-DR2 may represent a marker for susceptibility to FH in the North Chinese population.

ANASSOCIATIONSTUDYBETWEENESSENTIALHYPERTENSIONANDHLA-DRB1ALLELESTaoZhenyin(陶贞寅);ZhaoYan(赵岩);ZhuXilin(朱席林);ZhuKe(朱克);YuGuoping...

 
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