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   orthotopic 在 肿瘤学 分类中 的翻译结果: 查询用时:0.011秒
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orthotopic
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  原位
    Study on Behavior of Orthotopic Intra-ocular Tumors and Gene Therapy of Anti-angiogenesis
    原位眼内恶性肿瘤模型生物学行为及抗新生血管生成基因治疗研究
短句来源
    ORTHOTOPIC TRANSPLANT MODEL OF HUMAN PANCREATIC CANCER IN NUDE MICE AND THEIR BIOLOGICAL PROPERTIES
    两株人胰腺癌裸小鼠胰腺内原位移植模型的建立及其生物学特性
短句来源
    THE EXPERIMENTAL STUDY OF CHANSU LIPOSOME ON MURINE BLADDER ORTHOTOPIC TRANSPLANTATION BLADDER CANCER
    蟾酥脂质体对小鼠膀胱原位移植性膀胱癌的抗癌作用研究
短句来源
    Establishment of a model of human gastric cancer in nude mice via orthotopic transplantation
    建立裸小鼠人胃癌原位移植模型的一种新方法
短句来源
    Invasive and matastatic characteristics of an orthotopic transplant model of huamn stomach cancer in nude mice
    裸小鼠人胃癌原位移植模型的浸润转移特征
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  “orthotopic”译为未确定词的双语例句
    The Effect of CD3AK Cell on Tumor Metastasis and Recurrence after Radical Hepatectomy in a Patient-like Orthotopic Nude Model Bearing Human Hepatocellular Carcinoma with High Metastatic Potential
    CD3AK细胞对人肝癌裸鼠高转移模型肝癌根治切除术后肿瘤转移复发的影响的研究
短句来源
    Methods:Nude mice bearing orthotopic xenografty highly metastatic model HCC(LCI-D20) were randomly divided into 4 groups, they were control group (saline solution), interferon treatment group (IFN-α2b), 5-FU treatment group and combined treatment group(both 5-FU and IFN-α2b).
    方法裸鼠人肝癌转移模型(LCI-D20)40只,随机分成4组即对照组(生理盐水)、干扰素组(IFN-α2a)、5-FU组和联合组(5-FU与IFN-α2a)。
短句来源
    The orthotopic neobladder was created by using 65 cm of distal ileum,with 10—12 cm being used to construct the afferent tubular limb.
    术中取回肠袢约65 cm,其中近端10~12 cm作为抗返流输入道,远端53~55 cm U形折返缝合成球形肠膀胱。
短句来源
    A model of human osteosarcoma with spontaneous highly pulmonary metastasis in nude mice by orthotopic transplantation and studies on its biological characteristic
    人骨肉瘤自发性高肺转移模型的建立及其生物学特性初探
短句来源
    Establishment of human breast cancer metastasis SCID mouse model by orthotopic transplantation and study of its biological features
    免疫双缺陷鼠人乳腺癌转移模型的生物学特性研究
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  orthotopic
Intra-abdominal hypertension is an independent cause of acute renal failure after orthotopic liver transplantation
      
Orthotopic liver transplantation was performed in two allogeneic rat strain combinations, one with fatal immunosuppression despite a complete major histocompatibility complex mismatch.
      
Combined therapy of p53-wt and drug in an orthotopic multidrug-resistant human lung cancer model
      
In order to understand the allograft rejection in orthotopic liver transplantation (OLT), an allograft rejection rat model was established and studied by proteomic approach.
      
Chemotherapy of multidrug-resistant human lung cancer combined with an MDR1 ribozyme retroviral vector in an orthotopic model
      
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This paper reports the re-sult of an experiment on the anticarcino-genic effect of liver targeted drug deli-very system-mitoxantrone-polybutylcyano-acrylate-nanospheres (DHAQ-PBCA-NS)by using a model of heterotopic and ortho-topic transplantation of human hepatocel-lular carcinoma (HCC) in nude mice. Nosignificant difference was noted betweenthe anti-HCC effects of mitoxantrone anddexerubicin, but the anti-orthotopic trans-planting HCC effect of mitoxantrone-nano-spheres was obviously higher than that...

This paper reports the re-sult of an experiment on the anticarcino-genic effect of liver targeted drug deli-very system-mitoxantrone-polybutylcyano-acrylate-nanospheres (DHAQ-PBCA-NS)by using a model of heterotopic and ortho-topic transplantation of human hepatocel-lular carcinoma (HCC) in nude mice. Nosignificant difference was noted betweenthe anti-HCC effects of mitoxantrone anddexerubicin, but the anti-orthotopic trans-planting HCC effect of mitoxantrone-nano-spheres was obviously higher than that ofmitoxantrone and dexerubicin by compari-son of tumor inhibition rates and prolifera-ting cell nuclear antigen (PCNA). Theresult showed the applicability of mitoxan-trone-nanospheres.

作者用常位(肝内)及异位(右腋皮下)移植人肝癌动物瘤株(LTNM_4)裸小鼠模型,以阿霉素(ADR)、米托蒽醌(DHAQ)作比较,对肝靶向制剂米托蒽醌毫微球(DHAQ-PBCA-NS)的抗肝癌效果进行了研究。结果表明:ADR、DHAQ和DHAQ-PBCA-NS对常位移植人肝癌的抑瘤率分别为60.07%、67.49%和99.44%。对异位移植人肝癌的抑瘤率分别为80.03%、86.18%和92.90%。用抗增殖细胞核抗原(PCNA)单克隆抗体PC_(10),采用ABPAP法显示细胞增殖活性,ADR、DHAQ和DHAQ-PBCA-NS的PCNA计数分别为85.5±12.7%、76.0±13.4%和31.0±23.0%。经t检验显示,DHAQ抗肝癌效果与ADR相当,而DHAQ-PBCA-NS抗常位移植人肝癌的效果明显优于ADR和DHAQ,具有应用研究前景。

Various doses of chansu liposome has a considerable suppressive effect on tumor cells of human bladder transitional cell carcinoma cell line BIU-87. and was dose dependent. The chansu liposome has the capability to reduce the nuclear orthotopic DNA content of human bladder transitional cell carcinoma cell line BIU-87 as compared to the controls; DNA index reduced from 4. 09 in the control group to 2. 55 in the 10μg/ml group of chansu liposome; DNA ploidy changed from high to low ploidy. The differenees...

Various doses of chansu liposome has a considerable suppressive effect on tumor cells of human bladder transitional cell carcinoma cell line BIU-87. and was dose dependent. The chansu liposome has the capability to reduce the nuclear orthotopic DNA content of human bladder transitional cell carcinoma cell line BIU-87 as compared to the controls; DNA index reduced from 4. 09 in the control group to 2. 55 in the 10μg/ml group of chansu liposome; DNA ploidy changed from high to low ploidy. The differenees were statistically significant(P<0. 05). With light microscopy, the group of chansu liposome showed vacuolar degeneration in the BIU-87 cell plasma. The result demonstrated that the anti-cancer mechanisms of chansu liposome might be due to an inhibitory effect on DNA composition of tumor cells and hence the reduction of the malignancy of the tumor.

不同剂量的蟾酥脂质体对体外培养的人膀胱移行细胞癌BIU-87细胞生长有明显抑制作用,且存在药物剂量依赖性。应用图象分析仪(IAS)对癌细胞核DNA原位定量测定,结果随药物剂量的增加,癌细胞核DNA原位含量逐渐减低,DNA指数(DI)由对照组的4.09降为2.55,从DNA的倍体分布直方图上可见癌细胞由高异倍体向低异倍体转化,经统计学分析有显著性差异(P<0.05)。光镜下发现:癌细胞有明显的空泡样变性及核裸露。认为蟾酥脂质体的抗肿瘤作用与其抑制癌细胞DNA合成及减低肿瘤恶性度有关。

Controversy still exists in the liver transplantation as one of the surgical treatments for hepatic cancer.Of the 14cases of orthotopic liver transplantation performed in our institute since 1977,12 cases were primary liver cancer(PLC).No intraoperative and immediate postoperative death occured.Four cases survived for over 3 months,in whom 2 survived for over half a year,and 1 nearly 9 months.The main causes of death were liver failure,rejection, tumor recurrence and infection.The results and the indication...

Controversy still exists in the liver transplantation as one of the surgical treatments for hepatic cancer.Of the 14cases of orthotopic liver transplantation performed in our institute since 1977,12 cases were primary liver cancer(PLC).No intraoperative and immediate postoperative death occured.Four cases survived for over 3 months,in whom 2 survived for over half a year,and 1 nearly 9 months.The main causes of death were liver failure,rejection, tumor recurrence and infection.The results and the indication of liver transplantation for PLC are discussed.The liver cancer classification more suitable for PLC and selection of the surgical treatment are suggested. It is hold that the liver transplantation is justified for the PLC at stageⅠ,type B and stageⅡ.The reasons why the results of the liver transplantation were poor in China and in our institute are analyzed.It is believed that better results will be gained by means of more strict case selection,immprovement of surgical technique and Cyclosporin A(CsA)application.

LIVERTRANSPLANTATIONFORHEPATICCANCERXiaSuisheng夏穗生(InstituteofOrganTransplantation,TongjiMedicalUniversity,Wuhan430030)Abstra...

 
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