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   剂量-效应 在 药学 分类中 的翻译结果: 查询用时:0.172秒
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剂量效应    
相关语句
  dose-effect
    OBJECTIVE To study the fitting about S model dose-effect curve with the accumulation normal distribution function.
    目的研究S型剂量效应曲线的累积正态分布函数拟合。
短句来源
    CONCLUSION The Hill coefficient is considered not any physiological meanings in the mathematics model usually used in fitting pharmacodynamics S dose-effect curve.
    结论常用的药效学S型剂量效应曲线拟合的数学模型中,Hill系数无生理学含义。
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    Amiloride is of dose-effect relationship.
    amiloride药理作用具有剂量效应关系。
短句来源
    Fitting dose-effect curve with the accumulation normal distribution
    剂量效应曲线的累积正态分布拟合
短句来源
    There was a dose-effect relation within the range of concentrations 5 to 50μg/ml.
    在实验浓度范围5~50μg/ml内,存在剂量效应关系(r=0.9740,P<0.025)。
短句来源
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  dose-dependent
    The contr ibution of polymorphic CYP2C19to both N-demethylation and O-dealk ylation of fluoxetine are substrate dose-dependent and gene dose-depen dent.
    多态性CYP2C19对氟西汀代谢的作用均呈底物剂量依赖性和基因剂量效应
短句来源
    The results show that F951 inhibit the HL-60 cells proliferation significantly in the range of dosages studied, which indicated dose-dependent effects and synergistic effects while in combination with low-dose Ara-C.
    结果:F951在体外能有效地抑制HL一60细胞生长和增殖,且在实验剂量范围内呈剂量效应关系,与小剂量Ara一C联合应用呈显协同趋势。
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    The results showed that XK469 could inhibit H460 cells growth in vitro in dose-dependent manners, after being treated for 24h, the cellular growth inhibitory rate were 65.96%(10ug/ml), 75%(20ug/ml), 81.1%(40ug/ml), 85.64%(80ug/ml), 88.57%(120ug/ml).
    26.4%(20林岁ml)、54.85%(40林岁ml)、59.17%80(林g/ml)、86.97%(120林g/ml); (2)阿霉素和足叶乙贰均具有程度不一的抑制作用,并表现出时间效应和剂量效应的关系。
短句来源
    As aspirin,an known cyclooxygenase inhibitor,and dazo xiben,an known selective thromboxane synthetase inhibitor,their inhibitory effect on the platelet aggregation induced by arachidonic acid was much stronger than that induced by ADP. Radioimmuno-assay of TXB2 and PGE2 showed that econazole andclotrimazole 0.5-50nmol/L inhibited TXB2 synthesis in rat platelets in a dose-dependent manner with corresponding increase in PGE2 production.
    放射免疫法测定大鼠血小板产生的TXB_2及PGE_2发现益康唑和克霉唑在5~50 nmol/L浓度下,能抑制TXB_2产生,同时增加PGE_2生成量,并呈良好的剂量效应相关。
短句来源
    There exist a dose-dependent relation between Ru_(486)and IL-1 activity. Result indi-cated that either in vivo or in vitro study,on hemorrhagic or normal rats, GR mightbe an important mediator of IL-1 activity,i.
    体外实验同样发现:Ru_(486)可以有效地阻断皮质酮对巨噬细胞分泌IL-1的抑制作用,呈剂量效应关系。
短句来源
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  dose effect
    (2) it was possible to establish a dose effect calibration curve for doses above 5 Gy by adding Cyt-B and prolonging the cultural time, so that its value as a biological dosimeter for clinical application might be increased than before.
    以上结果提示:①辐射事故中当以染色体畸变估算大于6Gy受照者的剂量时,必须延长培养时间,有条件者加Cyt-B方可增加培养成功的机会,提供足够的分裂像。 ②改变培养条件,加Cyt-B并延长培养时间有可能制定出剂量上限高于5Gy的剂量效应刻度曲线,从而进一步提高其作为生物剂量计的临床应用价值。
短句来源
    Significant induction of sperm deformity (P<0.01) and dose effect relationship displayed when the earthworms were exposed to imidacloprid at the concentrations of more than 0.5mg/kg dry soil.
    实验结果表明,呲虫啉在浓度大于0.5mg/kg干土时对蚯蚓精子畸变率有明显影响(P<0.01),并呈现剂量效应关系;
短句来源
    Each dose of PLC inhibited ADP induced platelet aggregation significantly ( P <0 05) and this inhibition effect showed a significant time effect relationship and dose effect relationship.
    与阴性对照辅料组相比P <0 0 5 ,与阳性对照组相比 ,在ADP诱导时 ,10 0IU·kg-1组的抑制较弱 (P <0 0 5 ) ,而 80 0、10 0 0IU·kg-1组的抑制较强 (P <0 0 5 ) ,并呈一定的剂量效应和时间效应关系 ;
短句来源
    The curves of dose effect and dose toxicity were transfered into straight line and the reguession analysis was done by computer with the SPSS soften ware.
    用SPSS软件包进行剂量 效应曲线直线化回归分析。
短句来源
    Objective To explore dose effect relationship of cholinergic neurons and Nitric Oxide Synthase positive neurons express on basal forebrain after estrogen replacement treatment to ovariectomized rats.
    目的 探讨雌激素补充治疗对去卵巢大鼠胆碱能神经元及一氧化氮合酶 (NOS)阳性神经元表达的影响及剂量效应关系。
短句来源
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  dose-response
    Fenvalerate No. 3 gives a positive result at the concentration of 5 × 10~(-5)mol/L in the absence of the metabolic activation system and a dose-response relationship has been discovered.
    氰戊莉酯№3在不和体外活化系统,浓度为5×10~(-5)mol/L时结果为阳性,并能获得剂量效应关系.
短句来源
    DEC could markedly inhibit the contraction of thoracic aortic rings induced by KCl and norepinephrine(NE) in a concentration-dependent manner,shifted the cumulative dose-response curves of KCl and NE to right,and reduced the maximal efficacy of contraction in a nonCompetitive antagonistic manner. The pD'2 values of KCl and NE were 1.991 and 2.271 respectively.
    结果显示,DEC能显著抑制KCl和去甲肾上腺素(NE)引起的胸主动脉环收缩.使KCl和NE引起的动脉环收缩的剂量效应曲线右移,最大效应降低,均表现为非竞争性拮抗,其pD'2值分别为1.991和2.271。
短句来源
    AIM:Antipyretic dose-response and time-effect relationship of promethazine have been observedRESULTS:(1)Different antipyretic effect of promethazine on endotoxin-induced febrile rabbits were produced at 3 defferent dosage of 1mg,5mg,10mg/kg.
    目的:观察异丙嗪解热的剂量效应关系和时间效应关系:结果:(1)用1mg、5mg、10mg/kg体重三个剂量的异丙嗪给内毒素性发热的家兔注射后,产生了不同的解热效应。
短句来源
    Comparing the dose-response curves of benzalkonium chloride after different time, there was no statistical difference in proliferation of HTCFs between 4 hours and 24 hours(P>0.05).
    比较不同时间下的剂量效应曲线,4和24h没有显著差异(P>0.05)。
短句来源
    The time-response and dose-response effects of isoflurane preconditioning against focal cerebral ischemia injury in rats
    异氟醚预处理的脑保护作用及时间效应与剂量效应关系研究
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  dose-effect
No linear dose-effect relationships have been revealed for both physiological and biochemical parameters.
      
As for individual solvents, the action of their mixtures with water obeys the "dose-effect" law, with a greater influence of small doses of absorbed vapors on the polymer structure and optical activity.
      
The dose-effect dependence indicated stimulating effects of β-endorphin, DAGO, and DADLE on the proliferative response in the presence of phytohemagglutinin (PHA).
      
The curve of the dose-effect dependence of C6-AHB had a breaking point within the submillimolar (10-4 M) concentration range.
      
The phytotoxicity variation is maximum in a moderately polluted plot, where both very high and very low pollution levels were observed, which determines a substantially nonlinear dose-effect relationship.
      
更多          
  dose-dependent
Prodigiosin may effectively enter cells and promote the level of intracellular reactive oxygen species (ROSin) in a dose-dependent manner.
      
Doses ranging from 12.5-50 μM provided a dose-dependent reduction in the number of viable cells when compared to controls.
      
Surprisingly, FCM also determined that the percentage of hMSCs in G2/M-and S-phases also increased in a dose-dependent manner with respect to MDA concentration.
      
TfR mRNA was expressed in a dose-dependent manner and reached a peak at the 8th hour in HaCat cells (P >amp;lt; 0.05) whereas HIF-1α mRNA expression was not affected by UVB treatment (P>amp;gt;0.05).
      
PD153035, a selective inhibitor of EGFR tyrosine kinase, inhibited the TfR protein expression in UVB-treated cells in a dose-dependent manner (P >amp;lt; 0.05).
      
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  dose effect
The disorder parameter plays a determining role in the manifestation of the dose effect; when it decreases (>amp;lt;0.4), both the magnitude of the dose effect and the time required for its annealing strongly increase.
      
On the high-dose effect in the case of ion implantation of silicon
      
In order to gain insight into the mechanism of the so-called high-dose effect, several experiments were performed with ion implantation of phosphorus into silicon.
      
It was shown that neither the distinct dose effect nor its long annealing time can be explained unless the radiation-chemical aspect of irradiation is taken into account.
      
In the newborn only the high-dose (above 3×10-6 mol/l) effect was seen but in rats older than 5 days a mixed low-dose (below 3×10-6 mole/l)/high-dose effect was apparent.
      
更多          
  dose-response
The analysis of dose-response relationships indicated that when the hemodynamic scores in patients with hypertension were lower than 75 points, the RR of stroke at 75, 60, 45, 30 and 15 points were 2.85, 4.43, 4.54, 5.40 and 9.88, respectively.
      
Dose-Response Functions as Estimates of the Effect of Acid Precipitates on Materials
      
Presented and discussed are dose-response functions for structural metals and alloys (bronze, copper, weathering steel, zinc, aluminum, nickel and tin), stone materials (limestone and sandstone), paint coatings and glasses.
      
The Classification System of ISO 9223 Standard and the Dose-Response Functions Assessing the Corrosivity of Outdoor Atmospheres
      
A model and dose-response functions characterising the corrosivity of the outdoor atmospheres are described.
      
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