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contraction response
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  收缩反应
     ② Seratrodast and terbutalin inhibited the maximal contraction response induced by 60 mmol/L KCl, values of were IC50 7.28×10-6 mol/L and 3.36 ×10 -6 mol/L, respectively.
     ②对60mmol/LKCl诱发的气管条收缩,塞曲司特、特布他林均可抑制其最大收缩反应,IC50分别为7.28×10-6mol/L、3.36×10-6mol/L。
短句来源
     The relaxant response to 10 -6 mol/L ACh changed into a contractile response after preincubation with L-NNA in each group, while the contraction response to 10 -6 mol/L PE increased significantly.
     L 硝基精氨酸(L NNA)使各组肺动脉环对 10 -6mol/LACh反应由舒张变为收缩 ,对 10 -6mol/LPE的收缩反应显著增强。
短句来源
     Concentration-response curves were generated with ACh or PE (1×10–8~1×10–5 mol/L). Superoxide dismutes (SOD) activity and thecontent of malondialhyde (MDA) in artery tissues were detected. For TARs, LPS significantly reduced the contraction response to PEcompared with the vehicle group (P<0.01) and the curve of cumulative dose responses to PE in the LPS group shifted downward.
     结果显示:与对照组相比,LPS6h后胸主动脉对PE的收缩反应减弱(P<0.01),对PE(1×10–8~1×10–5mol/L)累积剂量反应曲线下移;
短句来源
     (2) Seratrodast and salbutamol inhibited the maximal contraction response induced by 60 mmol/L KCl;
     (2 )对6 0mmol/LKCl诱发的气管条收缩 ,塞曲司特、沙丁胺醇均可抑制其最大收缩反应 ;
短句来源
     Toosendanin enhanced slightly and reversibly the contraction response of curarized or denervated skeletal muscle to direct stimulation in rat. And this positively inotropic effect persisted when Ca~(2+) was replaced by Sr~(2+).
     川楝素能轻度可逆地增强箭毒化及去神经骨骼肌由直接刺激引起的收缩反应. 当用Sr~(2+)代替溶液中的Ca~(2+)时,这种正肌力作用仍能出现.
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  “contraction response”译为未确定词的双语例句
     CONCLUSION: In human RGA, the contraction response is mainly mediated by α_1-AR, of which α_(1A)-AR plays an important role, whereas α_(1B)- and α_(1D)-AR are not involved in the contraction response.
     结论:在RGA中NE引起的收缩效应主要由α_(1A)-AR介导,而α_(1B)-AR和α~(1D)-AR均不参与收缩效应。
短句来源
     EGb761 (1.75 g/L) significantly inhibited 44.13% of contraction response of colonic smooth muscle cells caused by Ach (P<0.01).
     2.4乙酞胆碱(ACh)(10一6mol/L)可明显增强结肠平滑肌细胞的收缩。 用EGb761预先孵育lmin,可抑制ACh效应的44.13%(P(0.01)。
短句来源
     EGb(1.75 g/L)significantly inhibited 44.13%of contraction response of colonic smooth muscle cells caused by ACh(P<0.01).
     EGb预先孵育 1min ,可抑制乙酰胆碱 (ACh)效应的 44 .1 3 % (P <0 .0 1 )。
短句来源
     Results Ligustrazine concentration-dependently depressed the contraction response to PE. The maximum percentage relaxation of cavernosal strips by ligustrazine was (74.1±6.2)% [ compared with control: (21.9±5.6)%, P<0.01 ].
     结果 川芎嗪浓度依赖性地舒张PE诱发的阴茎海绵体平滑肌收缩作用,最大舒张效应为(74.1±6.2)%[对照组为(21.9±5.6)%,P<0.01]。
短句来源
     Results: Cumulative concentration contractile response curves (CRC) for NE were competitively antagonized in rat pulmonary artery, mesenteric artery , caudal artery and portal vein by prazosin, WB4101, 5 MU, RS17053 and BMY7378. CEC shifted the NE CRC to the right and reduced the maximal contraction response in these vessels. The coefficients of determination with α 1A , α 1B and α 1D AR in pulmonary artery were 0.05,0.45 and 0.77;
     结果:哌唑嗪、WB4101 、5MU、BMY7378 和RS17053 分别竞争性地抑制血管对NE 的收缩效应,pA2 值与这些拮抗剂对克隆α1A、α1B、α1DAR 的pKi 值间的决定系数在肺动脉分别为0 .05、0.45、0.77 ;
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  相似匹配句对
     EFS induces contraction response in some sling fibers.
     EFS还诱导部分套索纤维产生收缩反应。
短句来源
     evaluation and response;
     评价与反馈;
短句来源
     Olfactory response of D.
     此外,被害蚕豆叶片中D对。
短句来源
     the cells were contraction;
     细胞突起呈念珠状变化。
短句来源
     Non-linear seismic response analysis of arch dam with contraction joints
     小湾拱坝模拟实际横缝间距的非线性地震反应分析
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  contraction response
The temperature-dependence of ATP release and contraction response evoked by different agonists were investigated in superfused guinea-pig vas deferens.
      
This model is further validated by accurately predicting the contraction response to a triangular P waveform.
      
Increasing [Ca2+]O enhanced the myocardial contraction response, and the maximal response was obtained at [Ca2+]O of 3.0?mM.
      
Feeding FO increased the maximal contraction response to acetylcholine in the ileum compared with all diets and in the colon compared with lard, and restored the depressed response to PGE2 and PGF2α in the ileum but not the colon of SHR.
      
Isolated arterial rings were exposed to diatrizoate (high osmolar CM), iohexol (low osmolar CM) or glucose solution, and the isometric contraction response was expressed as percentage of an initial KCl control contraction.
      
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The cholinergic effect of the methiodides of galanthamine and lycoramine, two alko- loids extracted from Lycoris sqamigera Maxim. and Narcissus papyraceus Ker-Gawl, was studied. Given intravenously, lycoramine and galanthamine caused, in rabbits and cats, a fall of blood pressure as well as an increase of the tonus and peristalsis of intestine. These responses could be antagonized by atropine. Solutions of galanthamine and lycora- mine (both 0.5%) caused contraction of the pupil of rabbits to a variable extent....

The cholinergic effect of the methiodides of galanthamine and lycoramine, two alko- loids extracted from Lycoris sqamigera Maxim. and Narcissus papyraceus Ker-Gawl, was studied. Given intravenously, lycoramine and galanthamine caused, in rabbits and cats, a fall of blood pressure as well as an increase of the tonus and peristalsis of intestine. These responses could be antagonized by atropine. Solutions of galanthamine and lycora- mine (both 0.5%) caused contraction of the pupil of rabbits to a variable extent. Galanthamine (1×10~(-6)g/c.c.) and lycoramine (1×10~(-5)g/c.c.) produced contraction of iso- lated guinea-pig ileum and still lower concentrations of both preparations increased the contraction induced by acetylcholine, BaCl_2,and histamine. The effect of galanthamine on the M-choline reactive system was 5-10 times stronger than that of lycoramine. It was shown that galanthamine and lycoramine increased the response caused by acetylcholine in the frog rectus and the leech dorsal-muscle, the effect of galanthamine being slightly stronger than lycoramine. In cats and rats, the two drugs caused an in- crease of contracting response of gastrocnemius muscle to nerve stimulation. The effect of galanthamine and lycoramine on the nervemuscle preparations was concerned with stimulating frequencies and doses. Higher frequencies (25-100/sec) and larger doses caused, in many instances, depression of muscle contration; but lower frequencies (5-10/ sec) and smaller doses produced, in most instances, muscle contraction. The effect of galanthamine was 5 times stronger than that of lycoramine. After treatment with atro- pine, the cholinesterase inhibitors, galanthamine, and lycoramine were found to increase the depression of muscle contraction induced by acetylcholine in large doses. Galan- thamine, lycoramine, and neostigmine antagonized muscle paralysis induced by d-tubo- curarine, but not by succinylcholine. Like neostigmine, galanthamine and lycoramine antagonized the ganglionic blockade produced by TEA and C_6, and also increased the contraction response of nictitating mem- brane to nerve stimulation. The stimulating effect of lycoramine on the central M- and N-choline reactive system was stronger than that of galanthamine, In mice, the LD_(50) of galanthamine, lycoramine, and neostigmine were found to be 0.958, 16.65, 0,174 mg/kg respectively. The usual toxic symptoms were: salivation, twitching, and convulsion. The animals died usually of respiratory paralysis.

力可拉明与加兰他明系由紫花石蒜及臭水仙中提得,本文报导了它们的碘甲烷盐对胆碱反应系统的影响.力可拉明与加兰他明静脉注射于家兔及猫引起血压下降、肠张力及蠕动加强,可为阿托品对抗.其0.5%的溶液不同程度地收缩家兔的瞳孔.较高浓度的加兰他明(1×10~(-6)克/毫升)与力可拉明(1×10~(-5)克/毫升)可使离体豚鼠迴肠收缩,较低浓度加强乙酰胆碱、氯化钡与组织胺对肠段的收缩作用,对M-胆碱反应系统的作用加兰他明比力可拉明大5-10倍.在水蛭背肌及蛙腹直肌标本上,证明加兰他明加强乙酰胆碱的作用稍大于力可拉明.在猫与大白鼠的试验证明该二药加强了刺激神经所致的腓肠肌收缩作用,对大白鼠坐骨神经-腓肠肌标本的作用与刺激频率及剂量有关,高频(25-100次/秒)和大剂量引起肌缩抑制者较多,而低频(5-10次/秒)和小剂量绝大多数引起肌缩加强.加兰他明比力可拉明作用约大5倍.如预先用阿托品处理,大量乙酰胆碱引起的肌缩抑制,加兰他明与力可拉明均可使之加强.加兰他明、力可拉明和新斯的明可对抗箭毒所引起的肌肉松弛,但对琥珀酰胆碱则反加重.加兰他明与力可拉明类似新斯的明能对抗TEA,C6所致的神经节阻断,亦能加强电刺激交感节前纤维...

力可拉明与加兰他明系由紫花石蒜及臭水仙中提得,本文报导了它们的碘甲烷盐对胆碱反应系统的影响.力可拉明与加兰他明静脉注射于家兔及猫引起血压下降、肠张力及蠕动加强,可为阿托品对抗.其0.5%的溶液不同程度地收缩家兔的瞳孔.较高浓度的加兰他明(1×10~(-6)克/毫升)与力可拉明(1×10~(-5)克/毫升)可使离体豚鼠迴肠收缩,较低浓度加强乙酰胆碱、氯化钡与组织胺对肠段的收缩作用,对M-胆碱反应系统的作用加兰他明比力可拉明大5-10倍.在水蛭背肌及蛙腹直肌标本上,证明加兰他明加强乙酰胆碱的作用稍大于力可拉明.在猫与大白鼠的试验证明该二药加强了刺激神经所致的腓肠肌收缩作用,对大白鼠坐骨神经-腓肠肌标本的作用与刺激频率及剂量有关,高频(25-100次/秒)和大剂量引起肌缩抑制者较多,而低频(5-10次/秒)和小剂量绝大多数引起肌缩加强.加兰他明比力可拉明作用约大5倍.如预先用阿托品处理,大量乙酰胆碱引起的肌缩抑制,加兰他明与力可拉明均可使之加强.加兰他明、力可拉明和新斯的明可对抗箭毒所引起的肌肉松弛,但对琥珀酰胆碱则反加重.加兰他明与力可拉明类似新斯的明能对抗TEA,C6所致的神经节阻断,亦能加强电刺激交感节前纤维所致的瞬膜收缩.力可拉明的中枢M-与N-胆碱反应系统的兴奋作用较明显,而加兰他明则较弱.静脉注射加兰他明、力可拉明与新斯的明对小白鼠的LD_(50)分别为0.958,16.65,0.174毫克/公斤,中毒症状为流涎、震颤、抽搐,动物死于呼吸麻痹.

Toosendanin enhanced slightly and reversibly the contraction response of curarized or denervated skeletal muscle to direct stimulation in rat. And this positively inotropic effect persisted when Ca~(2+) was replaced by Sr~(2+). Toosendanin also enhanced the spontaneous contraction of guinea pig's smooth muscle, but it had negtively inotropic effect on thecontraction of oardiac muscle evoked by direct stimulation in rat.

川楝素能轻度可逆地增强箭毒化及去神经骨骼肌由直接刺激引起的收缩反应.当用Sr~(2+)代替溶液中的Ca~(2+)时,这种正肌力作用仍能出现.川楝素对豚鼠平滑肌的自发收缩亦有增强作用,但川楝素对大鼠心肌由直接电刺激引起的收缩反应则具有负肌力作用.

In anesthetized rabbits,ethanolamine nitrate ester ferulate(ENF)(100μg/kg,i.v.)reduced systemic blood pressure by 39±12mmHg,but did notaffect ECG parameters.ENF(i.v.)improved myocardial ischemia inducedby pituitrin in anesthetized rats and rabbits.ENF(i.p.)could increase theresistance to hypoxia in mice.In anesthetized chest-opened dogs,ENF(i.v.)increased coronary blood flow and reduced systemic blood pressure.On isolatedrabbit aortic strips the contraction response induced by norepinephrine was antag-onized...

In anesthetized rabbits,ethanolamine nitrate ester ferulate(ENF)(100μg/kg,i.v.)reduced systemic blood pressure by 39±12mmHg,but did notaffect ECG parameters.ENF(i.v.)improved myocardial ischemia inducedby pituitrin in anesthetized rats and rabbits.ENF(i.p.)could increase theresistance to hypoxia in mice.In anesthetized chest-opened dogs,ENF(i.v.)increased coronary blood flow and reduced systemic blood pressure.On isolatedrabbit aortic strips the contraction response induced by norepinephrine was antag-onized by ENF(100μg/ml)or FA(500μg/ml).In rats,i.v.LD_(50) was 857mg/kg,p.o.LD_(50)>1200mg/kg.

合成的阿魏硝胺(乙醇胺硝酸酯的阿魏酸盐),具有明显的心血管效应,可使麻醉兔降低全身血压39±12mmHg,但对心电图无明显影响(iv)。它对抗垂体后叶素所致急性心肌缺血(iv),能增强小鼠耐缺氧能力(ip),并能增加麻醉狗的冠脉血流量(iv);并能明显抑制去甲肾上腺素(NE)引起的动脉血管条收缩。本品对小鼠的 LD_(50)为857mg/kg(iv),>1200mg/kg(PO)。

 
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