Methods Thirty-six adult C57Bl/6J mice were divided into 2 groups: retinal detachment model was set up in the left eyes of 18 mice by subretinal injection with 1.4% sodium hyaluronate in the experimental group, while the left eyes of other 18 mice underwent scleral puncture only as the control.
After the RD model was set up by subretinal injection with sodium hyaluronate, 5 μl NGF (1 μgμl) was injected into the vitreous body of the right eyes which were in the NGF group;
The groups were treated locally at traumatized cecum with 5 mL·kg-1 normal saline, sodium hyaluronate (50 mg·kg-1), or DCX-16(15 ,50,150,500 mg·kg-1) respectively during the operation. The degrees of peritoneal adhesion and incision healing were evaluated at d 14 postoperatively in order to find the most effective concentration of DCX-16 for the adhesion.
Results:Chitosan (0.1mg/ml) showed a significant (P<0.05) reduction in the proliferation of fibroblast cells relative to control and increased G 1 phase cell rate,while sodium Hyaluronate inhibited the proliferation of fibroblast cells at concentration of 1mg/ml.
All enrolled patients were randomly divided into 3 groups: M r 1.5×106-2.5×106 sodium hyaluronate group, M r 3×106 sodium hyaluronate group and M r 6×106 sodium hyaluronate group.
To investigate the effects of extraneous sodium hyaluronate (SH) on the levels of IL 1β and TNF α in serum and synovial fluid of the patients with osteoarthritis (OA).
Methods The porous matrices containing collagen Ⅰ and sodium hyaluronate were fabricated by the freeze-drying technique and were crosslinked by using 1-ethyl-3-(3-dimethyl aminopropyl) carbodiimide (EDC).
METHODS: 27 adult rabbits were randomly divided into four groups, which were carboxymethylchitosan group as A (10), sodium hyaluronate group as B(10), operative- control group as C(5) and normal control group asD (2).
Group B:Received hydrodissection using a solution containing MMC(0 2mg/ml). Group C:Received MMC dissolved in sodium hyaluronate(0 2mg/ml)which was injected into the empty capsular bag after phacoemulsification. Group D:Received MMC dissolved in irrigating solution (0 2mg/ml)which was used for irrigation.
Superoxide dismutase (SOD) from bovine erythrocytes was conjugated with sodium hyaluronate (HA) with a mean molecular weight of 106 to have greater anti-inflammatory activity in vivo.
The present paper reports on the curative effect of the 0.1% Sodium hyaluronate (Na—HA) eyedrops jointly manufactured by Guangzhou Red Cross Hospital and Guangzhou Institute of Medical & Pharmaceutical Industry.70 cases were studied.There were kerato-conjunctivitis sicca,lagophthalmos corneal fluorescein diffuse punctate epithelial lesion caused by contact lens, and keratitis punctata superficialis.The results showed effective treatment which occupied 95.7%. In the discussion,the authors point o...
108 patients underwent cataract extraction surgery and 82 patients underwent posterior chamber IOL implantion with the vis-coelastic substance of sodium hyaluronate. The corneal thickness, the intraocular pressure, the anterior chamber reactions , and the toxicity to human corneal endothelial cells were investigated.
AbstractWith chicken paw as an animal model, we studiedthe effects of sodium hyaluronate product(SHP)onthe heal of injured tendon and the formation of post-surgical tendon adhesions.The function of digit flexionangle and moving function of the tendon in SHP groupwere remarkably superior to those of tendons in physi-ological salt solution control group(P<0.01).Tendons of the experiment group healed well,theirsurface was smooth without adhesion. False sheathwas formed around the tendon,and there w...