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retinoic acid syndrome
相关语句
  维甲酸综合征
     During administration of As2O3,there were 55 patients suffering from abnormal liver function(79.7%),32 digestive symptoms(46.4%),28 edema(40.6%),13 Retinoic acid syndrome(RAS)(18.8%),5 allergy(7.2%),4 fever of unkown(5.8%),and 3 Q-T interval prolongation(4.3%).
     As2O3治疗过程中出现肝功能异常55例(79.7%),消化道症状32例(46.4%),水肿28例(40.6%),类维甲酸综合征13例(18.8%),过敏5例(7.2%),发热4例(5.8%),Q-T间期延长3例(4.3%)。
短句来源
     However ,in the course of induction-APL with RA or As2O3,70% patients suffered from hyperleukocytosis and 5%-25% patients contracted retinoic acid syndrome (RAS).
     但是在RA、As2O3诱导治疗APL的过程中,约70%发生高白细胞血症,约5%-25%发生维甲酸综合征(RAS)以及维甲酸样综合征。
短句来源
     Objective: Increasing of adhesion between leukemia cells and endothelial cells during all-trans retinoic acid(ATRA) treatment plays an important role in retinoic acid syndrome.
     目的:全反式维甲酸(all-trans retinoic acid,ATRA)治疗急性早幼粒细胞白血病,引起白血病细胞与内皮细胞之间黏附增加,是发生维甲酸综合征的重要原因。
短句来源
     There were 4 patients died from Retinoic acid syndrome(30.8%).
     其中类维甲酸综合征死亡4例(30.8%)。
短句来源
     Clinical Analysis of Retinoic Acid Syndrome Developed in 11 Pat ients with Acute Promyelocytic Leukemia
     11例急性早幼粒细胞白血病患者并发维甲酸综合征的临床分析
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  “retinoic acid syndrome”译为未确定词的双语例句
     Of 82 patients with acute promyelocytic leukemia(APL) who were treated with all trans retinoic acid(ATRA), 35 developed leukocytosis and 22 fatal side effects(15 with retinoic acid syndrome and 7 intracranial bleeding).
     用全反式维甲酸(ATRA)治疗82例急性早幼粒细胞白血病(APL),其中35例(427%)出现白细胞增多症,22例(268%)出现致命性副作用。
短句来源
     The coefficient of correlation between retinoic acid syndrome and CD 11b expression was r =0 884, P =0 000 on the 7th day, r =0 541, P = 0 030 on the 14th day and r =0 38, P = 0 230 on the 28th day.
     14d :r =0 5 41,P =0 0 3 0 ; 2 8d :r =0 3 8,P =0 2 3 0。
短句来源
     Objective To explore clynical features,best optional therapy and retinoic acid syndrome of the patients with acute promyelocytic leukemia(APL).
     目的 探讨急性早幼粒细胞白血病(APL)的临床特点、最佳治疗方案、维A酸综合征(RAS)的防治。
短句来源
     But now there are occasionally early tolerance to RA, relapse of the disease and retinoic acid syndrome which limit the application of RA during the period of RA treatment.
     但是,单用RA治疗有一定的缺陷:大剂量RA有较大毒副作用,治疗后易复发或出现对RA的抵抗性或耐药性。
短句来源
     Conclusion: Earlier recognition and appropriate treatment of hyper-leukocytosis and retinoic acid syndrome can reduce the mortality of APL during ATRA therapy.
     结论:早期识别ATR毒副作用,尽早治疗,可以降低APL患者早期死亡率。
短句来源
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  相似匹配句对
     The Preparation of Cis-retinoic Acid
     异维A酸的制备方法
短句来源
     Retinoic acid in experimental myopia
     视黄醛在实验性近视中的作用
短句来源
     Peracetic acid
     过氧乙酸
短句来源
     The Super Acid
     超强酸
短句来源
     SYNDROME
     Noonan氏综合征(附2例报告)
短句来源
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  retinoic acid syndrome
The current study has provided new information on mammalian neural crest in a well-established experimental model for normal and abnormal human development, including its use as a model for the retinoic acid syndrome.
      
Sweet's syndrome was followed by retinoic acid syndrome in one of these cases.
      
It was associated with a mild retinoic acid syndrome, an inflammatory syndrome occurring in 25% of patients treated with ATRA and characterized by features of capillary leakage with systemic inflammatory signs.
      
We report a case of Sweet's syndrome associated with retinoic acid syndrome in a patient with acute promyelocytic leukemia treated with all-trans retinoic acid (ATRA).
      
Sweet's syndrome associated with retinoic acid syndrome in a patient with promyelocytic leukemia
      
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Fifty two patients with newly diagnosed acute promyelocytic leukemia(APL) were treated with alltrans retinoic acid (ATRA)alone. Five cases of them died early within one month after starting of this therapy. Four patients died of leukostasis or retinoic acid syndrome related to ATRA treatment, except that one of intracranial hemorrhage resulting from severe thrombocytopenia associated with APL itself. The clinial manifestations and pathogenesis of these serious compliactions are reviewed consulting the...

Fifty two patients with newly diagnosed acute promyelocytic leukemia(APL) were treated with alltrans retinoic acid (ATRA)alone. Five cases of them died early within one month after starting of this therapy. Four patients died of leukostasis or retinoic acid syndrome related to ATRA treatment, except that one of intracranial hemorrhage resulting from severe thrombocytopenia associated with APL itself. The clinial manifestations and pathogenesis of these serious compliactions are reviewed consulting the relevant literatures, and the preliminary opinions about management are proposed.

52例初诊APL患者单用全反式维甲酸(ATRA)治疗,其中5例在治疗后1月内早期死亡。除1例因APL本身严重的血小板减少所致的颅内出血外,其余4例死于与ATRA治疗相关的白细胞淤滞或维甲酸综合征。结合有关文献复习了这些严重合并症的临床表现和发病机理,并提出初步的处理意见。

All-trans retinoic acid (ATRA) has been successfully used in differentiation induction therapy for acute promyelocytic leukemia (APL),which was pioneered in China. We observed the side effects,emphatically special side effects,and especially the leukostasis and retinoic acid syndrome that may lead to early death easily,during ATRA treatment in fiftytwo newly diagnosed patients with APL. These serious complications were discussed.

全反式维甲酸是由我国首创的诱导分化治疗急性早幼粒细胞白血病获得成功的药物。本文对52例新诊患者接受该药治疗时发生的副反应进行了观察,重点观察特殊副反应,尤其是易引起早期死亡的白细胞淤滞和维甲酸综合征,并对这些严重并发症作了讨论。

Fifty-three cases of newly diagnosed APL were treated with all-trans retinoic acid(ATRA).Hyperleukocytosis(>20×109/L)were caused by ATRA during inducing differentiation therapy in 58% of patients treated with ATRA(31/53 cases).Retinoic acid syndrome were found in 11%(6cases)of 54patients treated with ATRA,one case of RAS occured two episodes during initial remission induction therapy and antirelapse treatment.Five cases(9.4%)were early deaths at 4~10th day after beginning of treatment.Three...

Fifty-three cases of newly diagnosed APL were treated with all-trans retinoic acid(ATRA).Hyperleukocytosis(>20×109/L)were caused by ATRA during inducing differentiation therapy in 58% of patients treated with ATRA(31/53 cases).Retinoic acid syndrome were found in 11%(6cases)of 54patients treated with ATRA,one case of RAS occured two episodes during initial remission induction therapy and antirelapse treatment.Five cases(9.4%)were early deaths at 4~10th day after beginning of treatment.Three cases were associated with hyperleukocytosis.Nine patients of hyperleukocytosis group were associated with chemotherapy of HA or DA combinations.Complete remission rate of nonhyperleukocytosis group and hyperleukocytosis group were 82%(18/22 cases)and 77%(24/31 caese)respectively.Chemotherapy is a major effective approach to treat patients with hyperleukocytosis. The synthetic treaement still is extremely important for decreasing early death.

53例初诊急性早幼粒细胞白血病采用全反式维甲酸治疗,发生白细胞增多(>20×109/L)58%(31/53例),维甲酸综合征11%(6/54例次)。5例(9.4%)早期死亡,3例有白细胞增多。高白细胞组9例并用DA或HA方案化疗。非高白细胞组和高白细胞组的完全缓解率(包括早期死亡病例)分别为82%(18/22例)和77%(24/31例),化疗为目前对白细胞增多症的主要针对性治疗,综合性治疗对减低早期死亡仍居重要地位。

 
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