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The AC activity does not show as much variation in the different areas of the brain as the oxidative enzymes, which may mean that AC is more related to static maintenance metabolism of cells than to dynamic functional metabolism.
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On the basis of these criteria, we conclude that the isolated fiber cells are viable, with intact membranes and functional metabolism.
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| From the aspects of patho-morphology and functional metabolism, 51 cases of choriocarcinoma were studied by immunohistochemical and image-analytical methods. It was found that those having a higher level of 3-hCG were associated with. a predominance of syncytiotrophoblast (ST), a plexiform of nidi, a chorion-line arrange of tumor cells and the synchronous development of cytoplasm with nuclei, Those having a lower level of β-hCG, conversely, had a predomi nance of cytotrophoblast(CT)and/or Intermediate... From the aspects of patho-morphology and functional metabolism, 51 cases of choriocarcinoma were studied by immunohistochemical and image-analytical methods. It was found that those having a higher level of 3-hCG were associated with. a predominance of syncytiotrophoblast (ST), a plexiform of nidi, a chorion-line arrange of tumor cells and the synchronous development of cytoplasm with nuclei, Those having a lower level of β-hCG, conversely, had a predomi nance of cytotrophoblast(CT)and/or Intermediate cells,with a mass of nidi, a irregular arrange of the cells and non-synchronous develop ment of both cytoplasm with nuclei and CT with ST. It was suggested that there be a subtle correlation between the patho-morphology of choriocarcinoma and the function, and the combination of function withmorphology plays an important role in predicting the biologic behavior and the nature of choriocarcinoma. | 本文用免疫组化和图象分析的方法,从病理形态结合功能代谢的角度观察分析了51例子宫绒毛膜癌。发现-hCG含量高者,其细胞多以合体滋养细胞(ST)为主,且呈丛状生长并摸拟胎盘绒毛排列,癌细胞多同步发育;反之,STf-hCG含量低者,癌细胞则多以细胞滋养细胞和(或)中间型滋养细胞为主且呈片块状,细胞排列紊乱,发育不同步(P<0.05～0.01)。本结果提示,绒癌的病理形态与其功能代谢间有着十分微妙的关系。作者认为对绒癌等病理形态与生物学行为相关性较差的肿瘤,应引入机能形态学和动力形态学的观点。 | Objective To evaluate the functional metabolism of cryopreserved homologous heart valve and blood vessels. Method Heart valves and blood vessels were taken from cadavers and frozen with two step method in -196℃ for long term storage. The levels of lactate dehydrogenase(LDH), aspartate transaminase(AST) and the sugar consumption of the cultured frozen thawed samples were measured and compared with that of the fresh tissue. Result All the cryopreserved homografts(23￣1297days) had growth ability and... Objective To evaluate the functional metabolism of cryopreserved homologous heart valve and blood vessels. Method Heart valves and blood vessels were taken from cadavers and frozen with two step method in -196℃ for long term storage. The levels of lactate dehydrogenase(LDH), aspartate transaminase(AST) and the sugar consumption of the cultured frozen thawed samples were measured and compared with that of the fresh tissue. Result All the cryopreserved homografts(23￣1297days) had growth ability and metabolic activities in culture. However in the first week the enzymatic activities of LDH and AST were lower( t=5.625, P<0 01) and the growth of the cells were slowlier than that of the fresh group. There had been 33 cryopreserved samples applied clinically and the follow up results were satisfying. Conclusion The cryopreservation technique used in this study for preserving heart valves and blood vessels proved suitable for clinical application. | ①目的从功能代谢角度评价深低温保存同种血管和瓣膜的实际效果。②方法同种材料取自脑外伤死亡个体，修剪后以两段法完成程序降温，－１９６℃长期保存。复温后体外培养检测糖消耗量、乳酸脱氢酶（ＬＤＨ）和谷－草转氨酶（ＡＳＴ），结果与新鲜材料进行对照并统计学处理。③结果低温保存２３～１２９７ｄ的同种材料复温后皆有生长和代谢活性，培养７ｄ时其ＬＤＨ和ＡＳＴ活性较对照组明显降低（ｔ＝５．６２５，Ｐ＜０．０１），细胞生长也较新鲜组织滞后；已有３３例冻存材料应用于临床，获得满意的随访效果。④结论表明现行的血管和瓣膜低温保存技术已达到临床应用的要求。 | cases of signet ring cell oarcinoma of gastrointestinal tract were observed ultrastructurally. The result showed that there were three types of signet ring cell carcinoma: mucous type, microcapsular type and glycogenic type.Combined with mucin histochemical staining,the authors discussed the cell origin of signet ring cell carcinoma,the reason and significance of cancer cell variant morphosis.It was considered that signet ring cell carcinoma originates from the multipotential stem cell, and the ultrastructural... cases of signet ring cell oarcinoma of gastrointestinal tract were observed ultrastructurally. The result showed that there were three types of signet ring cell carcinoma: mucous type, microcapsular type and glycogenic type.Combined with mucin histochemical staining,the authors discussed the cell origin of signet ring cell carcinoma,the reason and significance of cancer cell variant morphosis.It was considered that signet ring cell carcinoma originates from the multipotential stem cell, and the ultrastructural morphological changes of cancer cells are the specific manifestations of their ahnormal differentiation or their variant functional metabolism. | 通过对３８例胃肠道印戒细胞癌进行超微细胞结构观察，发现印戒细胞癌可有三种类型，即粘液型、微囊型和糖原型。结合粘液组化染色，作者对印戒细胞癌的细胞起源以及癌细胞不同形态表现的原因和意义进行了探讨，认为印戒细胞癌起源于具有多潜能分化的干细胞，癌细胞超微结构形态特征的变化是其畸形分化或功能代谢不同的具体表现。 | | | | << 更多相关文摘 |
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functional metabolism
功能代谢
查询“functional metabolism”译词为用户自定义的双语例句
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