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autologous bone marrow
相关语句
  自体骨髓
     Methods: In the 7 patients, two received autologous bone marrow transplantation (ABMT) and five received autologous peripheral blood stem cell transplantation (APBSCT).
     方法: 7例恶性肿瘤中, 2例行自体骨髓移植( autologous bone marrow transplantation, ABMT),另 5例行自体外周血干细胞移植( autologous peripheral blood stem cell transplantation, APBSCT)。
短句来源
     Autologous Bone Marrow Transplantation Treated Leukemia with rIL_2/LAK Cells Purging
     rIL_2/LAK细胞净化的自体骨髓移植治疗白血病
短句来源
     IL-2/ALLO-LAK CELLS INFUSION AFTER AUTOLOGOUS BONE MARROW TRANSPLANTATION IN TREATMENT OF 5 CASES OF ACUTE LEUKEMIA
     IL-2/同种异体LAK细胞疗法用于自体骨髓移植后治疗急性白血病5例
短句来源
     Experiment Study on Treatment of Coronary Heart Disease by Autologous Bone Marrow CD34~+ Stem Cells Implanted into Infarction Myocardium
     自体骨髓CD34~+干细胞移植治疗冠心病心肌梗死的实验研究
短句来源
     An experimental study on autologous bone marrow mesenchymal stem cells induced with transforming growth factor β_1 for the repair of defect of auricular cartilage in rabbits
     转化生长因子-β_1诱导自体骨髓间质干细胞移植修复兔耳郭软骨缺损
短句来源
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  “autologous bone marrow”译为未确定词的双语例句
     The expression rate of VEGF mRNA in the bone marrow cells from AML patients (82%) was higher than the rates in normal subjects (30.76%) and AML patients with autologous bone marrow transplantation (41.67%).
     AML病人骨髓细胞VEGF表达阳性率(82%)明显高于正常人(30.76%)及骨髓移植后的AML病人(41.76%)。
短句来源
     The patients were divided into trial group[PCI+normal saline(NS)] and control group[PCI+autologous bone marrow mononuclear cells(BM-MNCs)] randomly.
     随机分为对照组[PCI+生理盐水(NS)]与试验组[PCI+自体骨髓单核细胞(BM-MNCs)]。
短句来源
     Experimental and Clinical Study of Trans-Coronary Injection of Autologous Bone Marrow Mesenchymal Stem Cells for Treatment of Acute Myocardial Infarction
     经冠状动脉骨髓间充质干细胞心肌内移植治疗急性心肌梗死的实验及临床研究
短句来源
     ①Twenty-four swines was anaesthetized by intramuscularly injection 200 mg Ketamine, then 20 mL marrow was extracted from right thighbone. According Fercoll method autologous bone marrow mononuclear cells were gotten and mixed with colloid gold solution, cultured for 12-16 hours.
     ①24只猪均以盐酸氯胺酮200mg臀部肌肉注射麻醉后,分别于各自右侧股骨抽取骨髓20mL,采用Fercoll法分离获得骨髓单个核细胞,加入胶体金溶液,培养12~16h待用。
短句来源
     Objective Clinical efficacy of autologous bone marrow of acute leukemia in complete remission using interleukin-2(IL-2) in vitro purging with combination of interferon-α(IFN-α) was observed.
     目的 观察白介素 2 (IL 2 )加干扰素 α(IFN α)体外净化完全缓解后的急性白血病骨髓 (BM)进行骨髓移植 (ABMT)的临床疗效。
短句来源
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  相似匹配句对
     Autologous Bone Marrow Stromal Cells for Neovascularization
     自体骨髓基质细胞移植后成血管作用的实验研究
     Studies on Purging of Autologous Bone Marrow in Leukenia
     白血病自体骨髓的净化研究概述
短句来源
     Analysis of Multivariates Effects of Autologous Bone Marrow
     影响自身骨髓移植疗效的多因素分析
短句来源
     Bone Marrow Necrosis
     骨髓坏死
短句来源
     Bone marrow was normal.
     骨髓造血细胞无明显异常。
短句来源
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  autologous bone marrow
These studies have used autologous bone marrow cells as well as peripheral blood-derived progenitor cells, which were delivered via intracoronary or intramyocardial routes near the infarct area.
      
Over the past several years, a number of investigators in Europe and North America have evaluated the use of GM-CSF in the setting of autologous bone marrow transplantation.
      
Autologous reinfusion of circulating haemopoietic progenitor and stem cells (blood stem cell transplantation) has emerged as an alternative to autologous bone marrow transplantation in a variety of malignant diseases.
      
Bone formation at a rabbit skull defect by autologous bone marrow cells combined with gelatin microspheres containing TGF-β1
      
The objective of the present study is to investigate the addition effect of transforming growth factor (TGF)-β1 on the bone formation at a rabbit skull defect induced by autologous bone marrow (BM).
      
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The viaointy of cryopreserved bone marrow cells used for autologous bone marrow transplantation were studied.1. The CFU_(GM) colony forming ability of normal bone marrow cells was estimated by three different culture methods. 2. Normal bone marrow samples from 11 individuals were cryopreserved in liquid nitrogen. The nucleated cell recovery rate, trypan blue exclusion rate and CFU_(GM) recovery rate were studied after different intervals of storage. It appears that the viability...

The viaointy of cryopreserved bone marrow cells used for autologous bone marrow transplantation were studied.1. The CFU_(GM) colony forming ability of normal bone marrow cells was estimated by three different culture methods. 2. Normal bone marrow samples from 11 individuals were cryopreserved in liquid nitrogen. The nucleated cell recovery rate, trypan blue exclusion rate and CFU_(GM) recovery rate were studied after different intervals of storage. It appears that the viability of CFU_(GM) did not change much even after 50 weeks of storage. 3. After a two-step centrifugation, approximately 80±2.6% of nucleated cells could be seperated. 4. A first case of clinical trail was also reported. After one month of cryopreservation, the nucleated marrow cells from a patient with cervical carcinoma were infused back. The total infused nucleated cell count was 0.53×10~(10) and the total infused CFU_(GM) was 0.27×10~6. No untoward reactions are found after autotrasfusion.

本文旨在研究自体骨髓移植中多量骨髓的冷冻保存问题。(1)比较了正常骨髓粒系定向造血干细胞(CFU_(GM))活力的三种测试方法。在体内扩散盒培养方法中,用环磷酰胺0.3mg/g代替照射处理小鼠。(2)11例正常骨髓标本冻存于液氮并定期复温观察有核细胞回收率、锥蓝拒染率及CFU_(GM)回收率。当骨髓标本长期冻存达50周时,上述指标未见明显下降。(3)用二步离心法浓集多量骨髓的有核细胞。有核细胞可回收82.5±2.6%,所得有核细胞体积仅为原骨髓体积的三分之一左右。(4)在上述实验研究基础上,本文冻存了一例宫颈癌患者的自体骨髓。一个月后回输给患者的有核细胞总数为0.53×10~(10),CFU_(GM)总数为0.27×10~6。输注后患者的情况良好。

The intensive chemotherapy or radiotherapy has now been applied in the treatment of cancer abroad so as to get a radical cure, but its application is restricted because of the serious suppression of bone marrow. Bone marrow is drawn out before chemotherapy, preserved in vitro for some time, and after the effects of the medicine disappear, retransfused into the body. This is what autologous bone marrow transplantation ( ABMT ) means. Thus the above-mentioned harmful effects can be avoided. Therefore, whether...

The intensive chemotherapy or radiotherapy has now been applied in the treatment of cancer abroad so as to get a radical cure, but its application is restricted because of the serious suppression of bone marrow. Bone marrow is drawn out before chemotherapy, preserved in vitro for some time, and after the effects of the medicine disappear, retransfused into the body. This is what autologous bone marrow transplantation ( ABMT ) means. Thus the above-mentioned harmful effects can be avoided. Therefore, whether or not we can effectively preserve cells and sustain its viability and function is indeed -the key to the successful use of ABMT. The article introduces the cryopreservation of bone marrow. The result attained is very satisfactory. The bone marrow of human beings is effectively preserved for three davs at 4℃. Recoverable rate of the nuclear, exelusion of trypon blue and colony-forming-unit culture ( CFU-C ) are 84%, 91% ar.d 97% respectively. When the bone marrow is preserved in liquid nitrogen, the viability and function of the cells can be sustained much longer. The recoverable rate of the nuclear cells, exclusion of trypon blue, DNA and CFU-C arc 76%, 89%, 77% and 79% respectively. Successful preservation of hematoiogic stem-cell in vitro provides predisposing factor fcr applying ABMT clinically.

在恶性肿瘤的治疗中,国外目前应用强烈化疗或放疗,以期达到根治之目的.但其严重的骨髓抑制大大地限制了它的应用.自身骨髓移植就是在化疗前从人体内抽出,并在体外保存一段时间,然后待药物的毒性作用消失再将其回输入体内.这就避免了上述的副作用.因此能否有效地保存细胞,维持其活力和功能是自身骨髓移植的关键.本文介绍了骨髓的保存方法,尤其是超低温保存.取得的结果是令人满意的.人骨髓于4℃可有效地保存3天,有核细胞、锥蓝拒染率和粒系定向干细胞(CFU—C) 的回收率分别为84%、91%和97%.骨髓贮存于液氮中,其细胞的活力和功能得以较长保存,有核细胞、锥蓝拒染率、脱氧核糖核酸(DNA)和CFU—C的回收率分别为76%、89%、77%和79%.骨髓造血干细胞在体外成功的保存,为临床开展自身骨髓移植提供了先决条件.

In an effort to evaluate the possible effect of cryopreserved autologous bone marrow infusions in man,11 patients with cancer were treated with high-dose chemotherapy or large-field radiotherapy followed by an infusion of cryopreserved autologous bone marrow harvested before the treatment. The result indicated that cryopreserved autologous bone marrow infusions hastened hematopoietic recovery in the patients who had received the above mentioned treatment, and the effect could be beneficial...

In an effort to evaluate the possible effect of cryopreserved autologous bone marrow infusions in man,11 patients with cancer were treated with high-dose chemotherapy or large-field radiotherapy followed by an infusion of cryopreserved autologous bone marrow harvested before the treatment. The result indicated that cryopreserved autologous bone marrow infusions hastened hematopoietic recovery in the patients who had received the above mentioned treatment, and the effect could be beneficial to the patients. The methods of harvesting autologous bone marrow cryopreservation and determination of cell vitality were described and discussed. It may be concluded that the procedure is safe for clinical trial. It seems to be a promising approach that may offer hope to cancer patients who have failed to respond to conventional therapeutic modalities.

本文报道了11例恶性肿瘤患者,大剂量化疗或大面积(全身)放射治疗后,使用冷冻保存的自身骨髓对加速造血功能恢复的初步效果。回输冷冻保存的自身骨髓,对受药物或射线抑制的造血系统有促进恢复和重建造血功能之效应。讨论了14例患者自身骨髓采取、冷冻保存和活性测定的方法,证明临床使用是安全可靠的。自身骨髓输注,对常规治疗无效的患者提供了新的治疗途径,但尚处于试验阶段,需累积更多的病例资料才能加以肯定。

 
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