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sle mice
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  sle小鼠
     0X4 positive LC density of NS group SLE mice increased compared with that of C57BI/6 mice.
     2.地塞米松组 SLE小鼠与 C57 BI/6小鼠、生理盐水组、黄茂1组、黄茂 11组 SLE小鼠相比 OX3及 OX4阳性 LC密度明显下降。
短句来源
     Study of the Effect of Astragalus Polysaccharides on the Density of Epidermal Langerhans Cell of SLE Mice
     黄芪多糖对SLE小鼠表皮朗格汉斯细胞密度影响的研究
短句来源
     2. Compared with all the other groups both the 0X3 positive LC density and 0X4 positive LC density of Dexamethasone group SLE mice decreased significantly.
     3.黄茂1组及黄茂D组SLE小鼠与C57 B rr6小鼠相比O X3X3阳性LC密度无明显变化对X4阳性LC密度升高;
短句来源
     We have study in normal C57BL6 mice and (NZB xNZW)Fl SLE mice how (Thy - 1 antigen) expresses and the act of PG2 and corticosteroid.
     本文初步观察了Thy-1抗原在正常C57BL6小鼠、(NZB×NZW)F1小鼠中的表达情况及药物黄芪多糖、皮质类固醇激素对SLE小鼠中DETC密度的变化情况。
短句来源
     Effect of dexamethasone on the antiphospholipid antibodies in SLE mice
     地塞米松对SLE小鼠6种抗磷脂抗体影响的研究
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  红斑狼疮小鼠
     The effect of astragalus polysacchrides on the antiphospholipid antibodies in SLE mice
     黄芪多糖对红斑狼疮小鼠6种抗磷脂抗体的影响
短句来源
     Objective:To study the effect of astragalus polysacchrides on anticardiolipin, antiphosphatidyl choline, antiphosphatidyl serine, antiphospha-tidyl inositol, antiphosphatidic acid and antiphosphatidyl ethanolamine antibodies (aCL, aPC, aPS, aPI, aPA, aPE) in SLE mice. Methods:19 NZB×NZW F1 female mice were divided randomly into 3 groups: group PG2I (25 mg/kg/d), group PG2II (50 mg/kg/d), group NS (0.2 ml/d).
     目的 :观察黄芪多糖 (PG2 )对红斑狼疮小鼠抗心磷脂 (anticardiolipin ,aCL)、抗磷脂酰胆碱 (antiphosphatidylcho line ,aPC)、抗磷脂酰丝氨酸 (antiphosphatidylserine,aPS)、抗磷脂酰肌醇 (antiphosphatidylinositol,aPI)、抗磷脂酸 (antiphosphatidicacid ,aPA)和抗磷脂酰乙醇胺 (antiphosphatidylethanolamine ,aPE) 6种自身抗体的影响。
短句来源
     The VCAM-1 protein straps cannot be detected by Westem Blotting method in normal mice kidneys, while the straps in SLE mice kidneys were obvious.
     用WesternBlotting法在红斑狼疮小鼠肾脏组织中可检测出VCAM 1蛋白条带; 而未发生红斑狼疮的小鼠肾脏组织中不能测得。
短句来源
     Conclusion The expression of VCAM-1 is remarkably manifolded in SLE mice. The VCAM-1 maybe has a promoting function in the process of lupus nephritis in the mice.
     结论 VCAM 1的表达在红斑狼疮小鼠肾脏组织中明显增高,说明VCAM 1在小鼠狼疮性肾炎的发病过程中具有促进作用。
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  sle模型鼠
     Conclusion Fetal thymus transplantation performed significant therapeutic effects in SLE mice,and it could be used in clinical treatment of SLE.
     结论胚胎胸腺移植对SLE模型鼠有显著治疗效果,有望运用于临床SLE的治疗。
短句来源
     Conclusion Fetal thymus transplantation perform significant therapeutic effects on SLE mice and it could be used in clinical treatment of SLE.
     结论胚胎胸腺移植对SLE模型鼠有显著治疗效果,有望运用于临床SLE的治疗。
短句来源
  “sle mice”译为未确定词的双语例句
     Polymorphism of interleukin 10 receptor alpha chain(IL-10RA) gene and its relationship with phenotypes in SLE mice
     IL-10RA基因多态性及其与系统性红斑狼疮关系的研究
短句来源
     4. Dexamethasone and astragalus polysaccharides can decrease urine protein and improve the injury of kidney of SLE mice.
     4.黄茂多糖低剂量、高剂量及地塞米松均可明显降低SLE /J’鼠的尿蛋白,改善其肾脏损伤。
短句来源
     ② Microencapsulated thymocytes made a significant therapeutic effect to SLE mice after their being transplanted into model animals’ abdomens.
     ②微囊化胸腺细胞移植方法对SLE模型动物的治疗有显著效果 ;
短句来源
     Through detecting IL — 6 and IFN-y of Peripheral blood and observing pathology consequence of liver and kidney, we try to observe mechanism and curative effect of Qu Du capsule which is used to cure SLE mice with LPS induction in the aspect of immunology and histology and study therapeutical effect of Qu Du capsule deeply.
     p LPS诱导SLE样小鼠,给药15天,通过外周血IL—6和IFN-γ水平的测定以及肝脏和肾脏的病理观察,试图从免疫学、组织学角度透视中药祛毒胶囊治疗LPS诱导的狼疮样小鼠的机理和疗效,对祛毒胶囊的治疗作用进行深入研究。
短句来源
     Objective It remains unknown whether there is a correlation between the level of anti DNA antibodies and pathological severity in SLE mice.
     目的探讨系统性红斑狼疮性小鼠抗DNA抗体水平的动态变化与疾病严重程度之间的关系。
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  sle mice
In this study, we analyzed changes in Fas expression on T lymphocytes after fetal thymus transplantation in SLE mice.
      


We have successfully built up SLE model of mice induced by bacterial lipopolysaccharide (LPS) according to WHO Immunology Research and Training Centre Tito Cavallo and Francisco.The model of mice also accord essentially with the pathological pattern of SLE.The experimental results showed that the T、Th、Th/Ts quantity of SLE mice is lower than that in normal,whereas that of Ts is higher.Treat with Lingdan tablet,a...

We have successfully built up SLE model of mice induced by bacterial lipopolysaccharide (LPS) according to WHO Immunology Research and Training Centre Tito Cavallo and Francisco.The model of mice also accord essentially with the pathological pattern of SLE.The experimental results showed that the T、Th、Th/Ts quantity of SLE mice is lower than that in normal,whereas that of Ts is higher.Treat with Lingdan tablet,a Chinese herbal prescription,and artesunate can increase the T、Th、Th/Ts quantity of mice,lwer the Ts quantity of mice.

用LPS诱导BALB/C小鼠制备了SLE样模型。苓丹片配青蒿琥酯及少量激素在改善小鼠一般状况、降低死亡率及升高T、Th、Th/Ts水平、降低Ts方面均有显著作用。

Objective It remains unknown whether there is a correlation between the level of anti DNA antibodies and pathological severity in SLE mice.MethodsAnti DNA IgG and IgM antibodies, blood BUN and urine protein in lupus prone BXSB mice with age varying from 1 to 6 month were detected quantitatively in our experiment.ResultsWe found that anti DNA antibodies in serum varied irregularly while the concentration of blood BUN and urine...

Objective It remains unknown whether there is a correlation between the level of anti DNA antibodies and pathological severity in SLE mice.MethodsAnti DNA IgG and IgM antibodies, blood BUN and urine protein in lupus prone BXSB mice with age varying from 1 to 6 month were detected quantitatively in our experiment.ResultsWe found that anti DNA antibodies in serum varied irregularly while the concentration of blood BUN and urine protein increased gradually with age.ConclusionThat the level of anti DNA antibodies do not parallel the pathological severity in BXSB mice and it be necessary to survey multiple different items for diagnosing SLE or determining its seriousness. [

目的探讨系统性红斑狼疮性小鼠抗DNA抗体水平的动态变化与疾病严重程度之间的关系。方法测定了不同月龄的狼疮性BXSB小鼠的各种抗DNA抗体,血尿素氮和尿蛋白质浓度。结果BXSB小鼠抗DNA抗体量的动态变化无规律性,但血尿素氮和尿蛋白质的浓度随鼠龄的增加而逐步升高。结论抗DNA抗体水平并不与BXSB小鼠疾病的严重程度相平行,提示在诊断SLE或判断其严重程度时应测定多项实验指标为宜

AIM To investigate the effects of TGP on immunologic changes associated with CJ S 131 induced SLE like model in mice. METHODS SLE like syndrome was induced by injection of CJ S 131 and CFA.Various doses of TGP were given by gavage once daily for 28 days. RESULTS The levels of IgG anti single stranded DNA(ssDNA) and histone autoantibodies were increased in sera four weeks after injection.The proliferation response of splencytes to ConA and LPS and the production of IL 1...

AIM To investigate the effects of TGP on immunologic changes associated with CJ S 131 induced SLE like model in mice. METHODS SLE like syndrome was induced by injection of CJ S 131 and CFA.Various doses of TGP were given by gavage once daily for 28 days. RESULTS The levels of IgG anti single stranded DNA(ssDNA) and histone autoantibodies were increased in sera four weeks after injection.The proliferation response of splencytes to ConA and LPS and the production of IL 1 were also increased. TGP(50,100,200 mg·kg -1 ·d -1 ,ig) inhibited the aboved changes of SLE like mouse model partly or completely. CONCLUSION The SLE mouse model was similar to idiopathic SLE in humans. TGP has modulating effects on alternations of immunity of SLE like mouse model.

目的 观察白芍总苷 (TGP)对空肠弯曲菌CJ S13 1诱导的小鼠SLE样改变的保护作用。方法 采用空肠弯曲菌CJ S13 1和CFA混合免疫动物 ,诱导小鼠SLE样改变。结果 TGP 5 0 ,10 0 ,2 0 0mg·kg-1·d-1× 2 8d ,ig能部分或完全拮抗血清IgG型自身抗体水平的升高 ,抑制ConA及LPS诱导的淋巴细胞增殖反应的增强和IL 1生成的增多。结论 一定剂量的TGP对小鼠SLE样改变具有一定的保护作用

 
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