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ropivacaine
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  罗哌卡因
    Methods 40 elderly patients under continuous epidural anesthesia(ASA gradeⅡ~Ⅲ,undergoing elective lower abdominal or lower extremity operations) were randomly divided into two groups: levobupivacaine with tramadol Group(GroupⅠ,n=20)and ropivacaine with tramadol Group(GroupⅡ,n=20).
    方法选择连续硬膜外麻醉下行下腹部、下肢手术患者40例,ASAⅡ-Ⅲ级,随机分为左旋布比卡因复合曲马多组(Ⅰ组,n=20)和罗哌卡因复合曲马多组(Ⅱ组,n=20)。
短句来源
    After operation,the microdose analgesic pump was connected to epidural catherter in two groups for 48h. In GroupⅠor GroupⅡ,levobupivacaine 100mg or ropivacaine 100mg with tramadol 300mg were diluted with normal saline to 100ml.
    术毕两组均连接微量止痛泵行PCEA 48h,镇痛液配制:Ⅰ组或Ⅱ组分别采用左旋布比卡因100mg或罗哌卡因100mg复合曲马多300mg加生理盐水稀释至100m l。
短句来源
    Results Average visual analog scale scores(VAS) within 2 h postoperative of saline, long-lasting lidocaine and ropivacaine group were (42.0±19.7)mm, (25.2±16.4)mm, (38.6±24.5)mm respectively . VAS were higher in the Saline group as compared with long-lasting lidocaine group(P<0.05) .
    结果术后2h对照组、长效利多卡因组、罗哌卡因组患者VAS评分分别为(42.0±19.7)mm、(25.2±16.4)mm和(38.6±24.5)mm,长效利多卡因组的VAS评分明显低于对照组,差异有统计学意义(P<0.05)。
短句来源
    100ml analgesia fluid contained 0.15% ropivacaine, 0.2mg fentanyl, and 0.5mg morphine in group RFM and 0.15% ropivacaine and 3 mg morphine in group RM.
    RFM组用0.15%罗哌卡因+芬太尼0.2mg+吗啡0.5mg配制镇痛液100ml; RM组用0.15%罗哌卡因+吗啡3mg配制镇痛液100ml;
短句来源
    Methods:Forty elderly patients were randomly divided into two groups: ropivacaine group(GR,n=20)and physiological saline control group(GS,n=20).
    方法:病人分为罗哌卡因组(GR,n=20)和对照组(GS,n=20),分别采用0.5%罗哌卡因和生理盐水硬膜外给药。
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  罗比卡因
    The effects of ropivacaine on the sodium channel in dorsal horn neurons
    罗比卡因对脊髓背角神经元钠电流特性的影响
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    A Clinical Study on Epidural Ropivacaine Labor Analgesia
    罗比卡因硬膜外分娩镇痛的临床研究
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    Comparison of 0.75% ropivacaine and 0.75% bupivicaine for CSEA in patients undergoing cesarean section
    0.75%罗比卡因与0.75%布比卡因腰麻-硬膜外联合麻醉应用于剖宫产手术的评价
短句来源
    Clinical Study on Conduction Blockade of Brachial Plexas Nerve with Ropivacaine
    罗比卡因应用于臂丛神经阻滞的临床研究
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    Comparison of 0.75% ropivacaine with 0.75% bupivacaine epidurally used for renal transplantion
    0.75%罗比卡因与0.75%布比卡因应用于肾移植术的比较
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  “ropivacaine”译为未确定词的双语例句
    Results: Time of consciousness disappear in ropivacaine group was 20% less than physiological saline group(P<0.05).
    结果:意识消失所需时间GR组比GS组快约20%(P<0.05);
短句来源
    Propofol diprivan concentration and dose in ropivacaine group were lower than control group(P<0.05).
    GR组的异丙酚效应室浓度(Ce)、用量均比GS组显著为低(P<0.05);
短句来源
    The MAP value 15 minutes after epidural injection,during consciousness disappear and 1 min after tracheal intubations in ropivacaine group were lower,compared with control group(P<0.05).
    GR组MAP在硬膜外用药15min、意识消失时、插管后1min,与GC组相比有显著性差异(P<0.05)。
短句来源
    Results The analgesic effect was satisfactory in ropivacaine group in postoperative 6 h, in Fentanyl transdermal system group in postoperative 6-48 h, and in postoperative 48 h in combination group.
    结果镇痛效果:A组术后6h内、B组术后6~48h内镇痛效果满意,C组在术后48h内镇痛效果满意;
短句来源
    Incidence of pruritus and vertigo in Fentanyl transdermal system group and combination group was higher than ropivacaine group, but without statistical difference (P>0.05).
    瘙痒、眩晕发生率B、C组略高于A组,但无统计学差异(P>0.05)。
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  ropivacaine
Dose-response study of spinal hyperbaric ropivacaine for cesarean section
      
Background: Spinal hyperbaric ropivacaine may produce more predictable and reliable anesthesia than plain ropivacaine for cesarean section.
      
The dose-response relation for spinal hyperbaric ropivacaine is undetermined.
      
This double-blind, randomized, dose-response study determined the ED50 (50% effective dose) and ED95 (95% effective dose) of spinal hyperbaric ropivacaine for cesarean section anesthesia.
      
Results: ED50 (95% confidence interval) of spinal hyperbaric ropivacaine was determined to be 10.37 (5.23~11.59) mg and ED95 (95% confidence interval) to be 15.39 (13.81~23.59) mg.
      
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Objective To investigate the effects of 0 75% Ropivacaine compared with 0 5% Bupivacaine for epidural anesthesia in Caesarean Section in order to provide basis of the clinical application of Ropivacaine Method 20 parturients (ASA Ⅰ~Ⅱ) were divided into two groups randomly Group 1:0 75% Ropivacain (n=10),group Ⅱ:0 5% Bupivacaine (n=10) In all patients epidural space L 2~3 was selected ,then the catheter was put upward 3cm 1% Lidocaine...

Objective To investigate the effects of 0 75% Ropivacaine compared with 0 5% Bupivacaine for epidural anesthesia in Caesarean Section in order to provide basis of the clinical application of Ropivacaine Method 20 parturients (ASA Ⅰ~Ⅱ) were divided into two groups randomly Group 1:0 75% Ropivacain (n=10),group Ⅱ:0 5% Bupivacaine (n=10) In all patients epidural space L 2~3 was selected ,then the catheter was put upward 3cm 1% Lidocaine 5ml as a test dose and five minutes later,the initial dose of Ropivacaine/Bupivacaine 8~15ml were injected The total dose of the study drugs were less than 20ml Results There were no significant difference of total dose,level and onset time of sensory block between two groups But in group Ⅰ: sensory motor differentiation was more obvious,more satisfactory analgesia and muscle relaxation were obtained with less changes of blood pressure and heart rate Conclusion Compared with 0 5% Bupivacaine,0 75% Ropivacaine provides more satisfactory sensory block,sensory motor block differentiation anesthesia and muscle relaxation with less effect on cardiovascular function and fewer adverse events

目的 比较0.75% 罗哌卡因和0.5% 布比卡因对剖宫产手术硬膜外麻醉的临床效果,为罗哌卡因临床应用提供客观依据。方法 20 例剖宫产术患者(ASAⅠ~Ⅱ级)随机分为二组,Ⅰ组:0.75% 罗哌卡因(n= 10 例);Ⅱ组:0.5% 布比卡因(n= 10 例)。取L2~3 行硬膜外穿刺,向上置管3cm ,注入1.0% 利多卡因5m l试验量,5 分钟后注入首次剂量罗哌卡因或布比卡因8~15m l,总量不超过20m l。结果 两组病人用药总量、感觉阻滞范围和起效时间无明显差异。Ⅰ组感觉运动阻滞分离较明显,止痛和肌松效果良好,对血压和心率影响小。结论 与0.5% 布比卡因相比,0.75% 罗哌卡因感觉阻滞完善,感觉和运动阻滞分离明显,止痛和肌松效果良好,对循环功能影响小,不良反应发生率低。

Objective To evaluate the clinical efficacy and tolerability of 0 75% ropivacaine versus 0 5% bupivacaine in epidural anesthesia in patients undergoing caesarean section Methods Sixty one patients were randomly designed to receive 0 75 ropivacaine (group Ⅰ,n=30))or 0 5% bupivacaine (group Ⅱ,n=31)epidural anesthesia respectively during caesarean section Sensory block (pinprick),motor block (modified Bromage scale),intraoperative pain(VAS score),quality...

Objective To evaluate the clinical efficacy and tolerability of 0 75% ropivacaine versus 0 5% bupivacaine in epidural anesthesia in patients undergoing caesarean section Methods Sixty one patients were randomly designed to receive 0 75 ropivacaine (group Ⅰ,n=30))or 0 5% bupivacaine (group Ⅱ,n=31)epidural anesthesia respectively during caesarean section Sensory block (pinprick),motor block (modified Bromage scale),intraoperative pain(VAS score),quality of anlge sia and abdominal wall relaxation were assessed together with adverse event Results The percent age of sensory block to T 6 level was higher and onset of sensory block to T 6 was shorter in group Ⅰ than those in group Ⅱ(P<0 01),the median of maximum cephalad sensory spread was higher with ropivacaine than with bupivacaine;Although the incidence of motor block did not differ between the groups 10min after the main dose,but a significantly lower incidence was found 30min after the main dose,and duration of complete recovery from motor block was shorter with ropivacaine than with bupivacaine (P<0 05) Significantly lower pain scores were observed at delivery,exteriorization and at last suture,and the quality of analgesia and abdominal wall relaxation were better in group Ⅰ than those in group Ⅱ(P<0 05 0 01) No severe adverse event was found during the observa tions Conclusion 0 75% ropivacaine provides a better sensory block and intraoperative analgesia than 0 5% bupivacaine when used epidurally in patients undergoing caesarean section,and the onset of motor block is slower and the recovery from motor block is faster with 0 75% ropivacaine

目的 评价0.75% 罗哌卡因用于硬膜外麻醉剖宫产手术的临床效果和耐受性,并以0.5% 丁哌卡因作为对照。方法 择期剖宫产手术病人61 例,硬膜外麻醉时随机分别接受0.75% 罗哌卡因(Ⅰ组,n= 30)或0.5% 丁哌卡因(Ⅱ组,n= 31),观察感觉阻滞(针刺法)、运动阻滞(改良Bro-m age评分)、术中疼痛(VAS评分)、镇痛和腹壁肌松质量及不良反应。结果 Ⅰ组术前和术中感觉阻滞平面达T6 病例的百分比高于Ⅱ组(P< 0.01),平面达T6 的时间短于Ⅱ组(P< 0.01),最高阻滞平面中位数高于Ⅱ组。Ⅰ组给首剂量后10 分钟时出现运动阻滞病例的百分比低于Ⅱ组(P< 0.05),而30 分钟时无明显差异。术后运动阻滞完全恢复时间Ⅰ组明显短于Ⅱ组(P< 0.05)。Ⅰ组在分娩、子宫缝合、最后缝皮时的疼痛VAS评分低于Ⅱ组(P< 0.05~0.01),镇痛和腹壁肌松质量优于Ⅱ组(P<0.05~0.01)。观察中无严重不良反应。结论 0.75% 罗哌卡因用于硬膜外麻醉剖宫产手术时其感觉阻滞及镇痛效果优于0.5% 丁哌卡因,运动阻滞起效较慢而恢复迅速。

Objective To compare ropivacaine pharmacodynamics with bupivacaine in epidural cesarean section Methods Parturients for elective cesarean section were divided into two groups and randomly received with either 8 15ml of 0 75% ropivacaine (n=10) or of 0 5% bupivacaine (n=10) for epidural anesthesia The spread levels of analgesic block and the elapsed times for completion of the widest spread,Bromage score and muscle relaxation,motor block...

Objective To compare ropivacaine pharmacodynamics with bupivacaine in epidural cesarean section Methods Parturients for elective cesarean section were divided into two groups and randomly received with either 8 15ml of 0 75% ropivacaine (n=10) or of 0 5% bupivacaine (n=10) for epidural anesthesia The spread levels of analgesic block and the elapsed times for completion of the widest spread,Bromage score and muscle relaxation,motor block and its duration,the efficacy of analgesia and visual analogue scale (VAS),Apgar score for neonates,adverse event during admission,blood pressure,and heart rate during operation were observed and compared Results 0 75% ropivacaine had a wider spread of sensory block than 0 5% bupivacaine,better analgesia and muscle relaxation,stronger motor block but with quicker recovery,more powerful in reducing both systolic and diastolic blood pressure in contrast to only reduced diastolic blood pressure Conclusion 0 75% ropivacaine is safe to parturients and neonates for cesarean section with a good foreground for clinical application

目的 将新型酰胺类局部麻醉药罗哌卡因的药效学与丁哌卡因进行比较。方法 选择行择期剖宫产的产妇20 例,分成两组进行硬膜外麻醉。随机在硬膜外注入0.75% 罗哌卡因(n= 10例)或0.5% 丁哌卡因8~15m l(n= 10例)。对镇痛平面及达到最高平面和最低平面所用时间、运动阻滞程度及恢复时间、术中镇痛效果、新生儿Apgar评分、不良反应的发生情况、血压和心率的变化进行观察。结果 罗哌卡因产生的麻醉平面广,镇痛效果和肌松效果好,运动阻滞效果好但作用消失快,能显著降低收缩压和舒张压,而丁哌卡因仅降低舒张压。结论 0.75% 罗哌卡因对产妇和新生儿安全,能满意地进行剖宫产手术,具有良好的临床应用前景。

 
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