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   lupus mice 在 中药学 分类中 的翻译结果: 查询用时:0.828秒
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lupus mice    
相关语句
  狼疮鼠
    RECENT EFFECT OF REALGAR ON THE RENAL FUNCTION OF LUPUS MICE
    雄黄对狼疮鼠肾功能的近期影响
短句来源
    Objective:To study the recent effect of realgar on the renal function of lupus mice.
    目的 :研究雄黄对狼疮鼠肾功能的影响。
短句来源
    Result:Three methods had therapeutic action on lupus mice with renal impariment. There was no significant difference among them(P>0 05).
    结果 :3种治疗方法对狼疮鼠肾损害均有治疗作用 ,3组间疗效差异无统计学意义 (P >0 .0 5 ) ;
短句来源
    Conclusion:Realgar has some therapeutic action on the renal impairments of lupus mice and hemutopoiesis inhibition and no liver toxicity is found in the early stage.
    结论 :雄黄对狼疮鼠肾损害有一定的治疗作用 ,早期未见造血抑制和肝毒性
短句来源
  狼疮小鼠
    ObjectiveTo investigate the effect of arsenic trioxide(ATO)on the autoimmunity and survival time in BXSB lupus mice.
    目的探讨三氧化二砷(Arsenic Trioxide,ATO)对BXSB狼疮小鼠自身免疫及其生存时间的影响。
短句来源
    MethodsThe model BXSB lupus mice were randomly divided into two groups equally,the ATO treated group and the control group,17 in each group. Mice in the ATO group were given intraperitoneal injection of ATO at the daily dose of 0.4 mg/kg,once every other day for 105 days or 90 days,respectively,and the observation lasted for 210 days.
    方法BXSB狼疮小鼠随机平分两组,即ATO治疗组和对照组,ATO0.4mg/(kg.d)隔日腹腔注射至90天和105天,观察至210天实验结束,比较两组小鼠生存时间的差异;
短句来源
    Effect of SHEN-YI,a Chinese herbal formula on ratio of Th1/Th2 cells within immune organs of MRL/lpr lupus mice
    肾怡对狼疮小鼠免疫器官内Th1/Th2细胞比例的调节作用
短句来源
    Effects of Arsenic Trioxide on the Autoimmunity and Survival Time in BXSB Lupus Mice
    三氧化二砷对BXSB狼疮小鼠自身免疫及其生存时间的影响
短句来源
    Objective To study the immunoregulatory mechanism of Langchuangjing Granule(LG)in different dosages in lupus mice.
    目的探讨狼疮静颗粒不同剂量对自发性狼疮小鼠部分免疫调节作用机制。
短句来源
更多       
  狼疮鼠
    RECENT EFFECT OF REALGAR ON THE RENAL FUNCTION OF LUPUS MICE
    雄黄对狼疮鼠肾功能的近期影响
短句来源
    Objective:To study the recent effect of realgar on the renal function of lupus mice.
    目的 :研究雄黄对狼疮鼠肾功能的影响。
短句来源
    Result:Three methods had therapeutic action on lupus mice with renal impariment. There was no significant difference among them(P>0 05).
    结果 :3种治疗方法对狼疮鼠肾损害均有治疗作用 ,3组间疗效差异无统计学意义 (P >0 .0 5 ) ;
短句来源
    Conclusion:Realgar has some therapeutic action on the renal impairments of lupus mice and hemutopoiesis inhibition and no liver toxicity is found in the early stage.
    结论 :雄黄对狼疮鼠肾损害有一定的治疗作用 ,早期未见造血抑制和肝毒性
短句来源
  狼疮样小鼠
    Influence of recipe of Lang Chang Fang on serum IL-6 and IL-10 in lupus mice
    中药狼疮方对狼疮样小鼠外周血IL-6和IL-10水平的影响
短句来源
    Effect of Langchuangjing Granule on Expression of CD4~+CD8~+ and CD54 in Peripheral Blood of Lupus Mice
    狼疮静颗粒对狼疮样小鼠外周血CD4~+、CD8~+及CD54表达的影响
短句来源
    Objective: To investigate Interleukin-6 and IL-10 expression in lupus mice and the effect of LangChangFang.
    目的 :探讨狼疮样小鼠外周血IL - 6和IL - 10水平及中药狼疮方对其影响。
短句来源
    LangChangFang inhibited IL-6 and IL-10 expression in lupus mice.
    ( 2 )模型组狼疮样小鼠血清Th2 细胞因子IL - 6和IL - 10水平明显高于对照组及各治疗组 ,差异显著 (P <0 0 5 )。
短句来源

 

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  lupus mice
The abnormal IL-10 response in lupus mice was derived from B cells with the marginal zone phenotype, and could be downregulated with inhibitory ODNs.
      
TLR-9 Activation of Marginal Zone B Cells in Lupus Mice Regulates Immunity Through Increased IL-10 Production
      
SAP levels in male lupus mice treated with danazol were significantly lower than normal control levels only at the 120 and 160 day time points.
      
The concentration of SAP, an acute phase reactant, was significantly decreased in danzoltreated female lupus mice at 80, 100, 120, 140 and 160 days of age when compared to vehicle-treated control mice.
      
Medication with danazol began 40 days after birth of the mice and resulted in a significant decrease in proteinuria in female but not male lupus mice.
      
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Objective: To investigate Interleukin-6 and IL-10 expression in lupus mice and the effect of LangChangFang. Methods: Chronic graft-verus-host disease model was used in this experiment. Interleukin-6 and IL-10 in serum was measured by ELISA. Results: IL-6 and IL-10 in lupus mice were higher than those of normal control. LangChangFang inhibited IL-6 and IL-10 expression in lupus mice. Conculsion: LangChangFang can be use for treatment of lupus as an immunosuppressive agent.

目的 :探讨狼疮样小鼠外周血IL - 6和IL - 10水平及中药狼疮方对其影响。方法 :采用慢性移植物抗宿主病小鼠模型 ,经中药狼疮方、强的松及联合治疗后分别检测血清抗ds -DNA抗体、和IL - 6、IL - 10水平。结果 :( 1)模型组血清抗ds -DNA抗体为 1.75± 0 .2 5 ,与对照组比较差异显著 ( 1.2 0± 0 .2 1,P <0 0 0 1) ;各治疗组血清抗ds-DNA抗体与对照组比较差异不显著 (P >0 0 5 )。 ( 2 )模型组狼疮样小鼠血清Th2 细胞因子IL - 6和IL - 10水平明显高于对照组及各治疗组 ,差异显著 (P <0 0 5 )。结论 :狼疮方具有免疫抑制作用 ,可抑制T和B细胞活化、减少Th2细胞因子的形成、自身抗体产生 ,有效的治疗狼疮性肾炎。

Objective To study the immunoregulatory mechanism of Langchuangjing Granule(LG)in different dosages in lupus mice.Methods Three -month female NZB /NZWF1mice were treated with LG in three differen t dosages for six weeks and then the effect of LG on t he expression of CD4 + ,CD8 + and CD54in peripheral blood was obse rved.Re-sults LG in different dosages showed a tend ency of increasing the content of CD4 + and CD8 + ,decreased the serum con-tent of CD54and inhibited the hyper...

Objective To study the immunoregulatory mechanism of Langchuangjing Granule(LG)in different dosages in lupus mice.Methods Three -month female NZB /NZWF1mice were treated with LG in three differen t dosages for six weeks and then the effect of LG on t he expression of CD4 + ,CD8 + and CD54in peripheral blood was obse rved.Re-sults LG in different dosages showed a tend ency of increasing the content of CD4 + and CD8 + ,decreased the serum con-tent of CD54and inhibited the hyper -expressions of CD54on the surface of lymphocyte and monocyte in plasma.T he above effects were stronger in middl e -and high -dosage of LG.Conclusion LG can improve the immune function an d restrain the excessive immunoreaction of lupus mice.

目的探讨狼疮静颗粒不同剂量对自发性狼疮小鼠部分免疫调节作用机制。方法运用狼疮静颗粒3种不同剂量,对3月龄雌性NZB/NZWF1狼疮模型小鼠进行干预治疗6周,观察其对各组小鼠CD4+、CD8+细胞及CD54表达的影响。结果中药狼疮静不同剂量有升高模型小鼠外周血CD4+、CD8+细胞的倾向,能降低血清CD54含量,抑制血浆淋巴细胞表面及单核细胞表面CD54的高表达,其作用以中、高剂量明显。结论狼疮静颗粒能改善和调节自发性狼疮小鼠细胞免疫功能,抑制过亢的免疫反应。

Objective:To study the recent effect of realgar on the renal function of lupus mice.Methods:16 lupus mices are divided into 3 groups irrigated with realgar,realgar allied prednisone and starch suspesion of prednisone respectively for 3 months. BUN,WBC,Cr,RBC,ALT were tested once a month.Result:Three methods had therapeutic action on lupus mice with renal impariment.There was no significant difference among them(P>0 05).And the obvious toxic action to the hematopoiestic system and liver is not...

Objective:To study the recent effect of realgar on the renal function of lupus mice.Methods:16 lupus mices are divided into 3 groups irrigated with realgar,realgar allied prednisone and starch suspesion of prednisone respectively for 3 months. BUN,WBC,Cr,RBC,ALT were tested once a month.Result:Three methods had therapeutic action on lupus mice with renal impariment.There was no significant difference among them(P>0 05).And the obvious toxic action to the hematopoiestic system and liver is not found.Conclusion:Realgar has some therapeutic action on the renal impairments of lupus mice and hemutopoiesis inhibition and no liver toxicity is found in the early stage.

目的 :研究雄黄对狼疮鼠肾功能的影响。方法 :将 1 6只狼疮鼠随机分为 3组 ,分别给予雄黄、雄黄 +强的松、强的松的淀粉悬液灌胃 ,治疗 3个月 ,每月 1次测定小鼠血清尿素、肌酐、白细胞、血红蛋白、转氨酶。结果 :3种治疗方法对狼疮鼠肾损害均有治疗作用 ,3组间疗效差异无统计学意义 (P >0 .0 5 ) ;且对造血和肝脏无明显的毒性作用。结论 :雄黄对狼疮鼠肾损害有一定的治疗作用 ,早期未见造血抑制和肝毒性

 
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