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microbial metabolites
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  “microbial metabolites”译为未确定词的双语例句
    C-1027, a new macromolecular peptide antitumor antibiotic produced by Streptomyces globisporus C-1027. was discovered during the screening of microbial metabolites.
    C-1027是我所从珠状孢子链霉菌C-1027(streptomyces globisporus C-1027)代谢产物中,用精原细胞法筛选出来的一个新的大分子蛋白类抗肿瘤抗生素。 它是由一条由110个常见氨基酸所组成的酸性蛋白和一个脂溶性发色团所构成。
短句来源
    The new antitumor antibiotic C1027 produced by Streptomyces globisporous C-1027 was discovered during the screening of microbial metabolites.
    C1027是我所从湖北省土壤放线菌产物中发现的一种新的大分子蛋白类抗肿瘤抗生素。 它由一个酸性蛋白和一个发色团构成,发色团具有新的烯二炔类结构,是C1027分子的活性部分。
短句来源
    In the course of screening for inhibitors of cholesterol biosynthetic enzyme from microbial metabolites, a physiologically active compound-SIPI-8926-Ⅱ was isolated from Fusarium fungi SIPI-8926 by solvent extraction, Silica Gel and LH20 column chromatography etc.
    在筛选微生物来源的胆固醇生物合成酶抑制剂过程中,应用硅胶柱层析、LH20凝胶柱层析和重结晶等方法,从镰孢属真菌SIPI-8926菌株中。 分离出具有生理活性的化合物SIPI-8926-Ⅱ。
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  microbial metabolites
Microbial metabolites were completely characterized by spectral methods, including 1H-NMR and 13C-NMR spectroscopy.
      
Large scale fermentation with Streptomyces lavendulaeL-105 and Rhizopogonspecies (ATCC 36060) have resulted in the isolation of four microbial metabolites.
      
The hypothesis was studied that intestinal microbial metabolites play a role in the pathogenesis of inflammatory bowel disease.
      
Effects of microbial metabolites on catalase activity and growth ofStaphylococcus aureus 6538 P
      
ultimum or disease severity on cotton seedlings, suggesting that time-dependent microbial processes or microbial metabolites significantly contributed to suppression of P.
      
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In the course of screening for inhibitor of cholesterolbiosynthetic enzyme from microbial metabolites,a physiohgically active compound xas isolated from strain SIPI-8915.The structure of the activecompound was elucidated to be identical with that of Compactin by mea-ns of physico-chemical properties,UV, IR,MS(EI-MS,HRMS).NMR(1H and 13C)spectra.

菌株SIPI-8915经麦芽糖—蛋白胨培养基培养,发酵液于酸性条件下经乙酸乙酯萃取,硅胶柱层分离纯化、结晶和重结晶得一白色针晶,熔点150~152℃。分子式C23H34O5。其甲醇溶液在230,237、246nm处呈吸收高峰。高分辨质谱显示M+(m/z)390.2392。经1H.NMR、1H-HCOSY谱以及13C-NMR(DEPT)和13C-1HCOSY谱等数据,证实SIPI-8915产生的物质与Compactin为同物。

In the course of screening for inhibitors of cholesterol biosynthetic enzyme from microbial metabolites, a physiologically active compound-SIPI-8926-Ⅱ was isolated from Fusarium fungi SIPI-8926 by solvent extraction, Silica Gel and LH20 column chromatography etc.The structure of the active compound[7-hydroxy-3-(4-hydroxyphenyl)-4H-1-benzopyran-4-one] was elucidated to be identical with that of daidzein by means of physico-chemical properties,UV,IR,NMR(1H and ̄(13)C) spectra.

在筛选微生物来源的胆固醇生物合成酶抑制剂过程中,应用硅胶柱层析、LH20凝胶柱层析和重结晶等方法,从镰孢属真菌SIPI-8926菌株中。分离出具有生理活性的化合物SIPI-8926-Ⅱ。通过对其理化特性、UV、IR、MS、NMR( ̄1H和 ̄(13)C)等光谱的分析,确定其结构为:7-羟基-3-(4-羟苯基)-4H-1-苯并吡喃-4-酮,与文献报道的大豆黄酮(daidzein)结构一致。

We used a stably transfected cell line carrying the promoter region of human VCAM1 gene fused to the coding region of firefly luciferase gene to screen samples that prevent the TNFinduced stimulation of VCAM1 transcription from microbial metabolites.In the course of screening, three physiologically compounds KS5555E,F,G were isolated from actinomyces KS5555 by solvent extraction, ODS column chromatography and HPLC etc. These compounds showed strong inhibitory activity for the transcription of...

We used a stably transfected cell line carrying the promoter region of human VCAM1 gene fused to the coding region of firefly luciferase gene to screen samples that prevent the TNFinduced stimulation of VCAM1 transcription from microbial metabolites.In the course of screening, three physiologically compounds KS5555E,F,G were isolated from actinomyces KS5555 by solvent extraction, ODS column chromatography and HPLC etc. These compounds showed strong inhibitory activity for the transcription of firefly luciferase gene fused to the promoter region of the human VCAM1 gene, the values of IC50were 0.32, 0.14, 0.19μmol/L respectively. The structures of KS5555 E,F,G were elucidated to be identical with the acylCoA synthetase inhibitor triacsin C,D,A by means of physicochemical properties and UV, MS spectra and HPLC analysis.

使用一个含有人VCAM-1基因启动子和荧光素酶编码基因的转染细胞株,从微生物代谢产物中筛选能够抑制由TNF-α诱导的VCAM-1表达的活性物质。在筛选过程中,应用有机溶媒萃取、ODS柱层析及HPLC等方法,从一株放线菌KS-5555的发酵液中分离到了KS-5555-E、F、G3种生物活性物质。它们对与人VCAM-1基因的启动子相连接的荧光素酶基因的表达显示出较强的抑制活性,其IC50值分别为0.32、0.14、0.19μmol/L。经各种理化特性及UV、MS、HPLC等分析,确定化合物KS-5555-E、F、G分别与脂酰CoA合成抑制剂triacsinC、D、A的结构相同。

 
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