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diclofenac choline
相关语句
  双氯芬酸胆碱
     Determination of the mean drug concentration-time curve of diclofenac choline in rabbits aqueous humor
     家兔房水中双氯芬酸胆碱的平均药-时曲线的测定
短句来源
     High performance liquid chromatograpy with methanol-actonphosphate (25: 25: 50) as liquid phase and Zor bax SBC 18 colorimetric column as solid phase was used to determine the concentration-time curve of diclofenac choline.
     采用甲醇-乙腈-pH6.4磷酸盐(25:25:50)为流动相,ZorbaxSBC18色谱柱为固定相的高效液相色谱法测定各时间点房水中双氯芬酸胆碱的质量浓度。
短句来源
     Results Diclofenac choline was detected in rabbit aqueous humor only 15 minutes after its topical administration at a single dose of 100 μL. Not interfaring peak for contaminating material was seen. The mean drug concentration-time curve was established by plotting the concentrations of diclofenac choline in aqueous humor vs time.
     结果家兔单剂量应用双氯芬酸胆碱滴眼液100μL后,房水中15min后即可检测到药物,且无其他杂质峰干扰,用不同时间点房水中的双氯芬酸胆碱药物质量浓度对时间作图,得其药-时曲线。
短句来源
     Diclofenac choline in the aqueous humor reached its Cmax at 0. 5 hour after its application and was eliminated completely 12 hours later.
     结论药-时曲线显示,给药后0.5h房水中双氯芬酸胆碱滴跟液质量浓度达到峰值,12h基本代谢完全。
短句来源
  “diclofenac choline”译为未确定词的双语例句
     Methods Twenty-four rabbits was randomly assigned to eight time-groups. 100 LμL of diclofenac choline ( DAC ) drops was topical administrated to the rabbit eyes, and the aqueous humor samples in eight different time-points were taken.
     方法取24只家兔,随机平均分成0.25、0.5、0.75、1、2、4、8、12h8个时间组,用微量进样器滴入双氯芬酸钠胆碱(DAC)滴眼液100μL,分别于8个时间点取不少于200μL的房水样品。
短句来源
  相似匹配句对
     Synthesis of diclofenac acid-choline
     双氯芬酸胆碱的研制
短句来源
     PREPARATION AND DETERMINATION OF DICLOFENAC ACID-CHOLINE EYE DROPS
     双氯芬酸胆碱滴眼液的制备和含量测定
短句来源
     Diclofenac sodium synthesis
     双氯灭痛合成的研究
短句来源
     SYNTHESIS OF DICLOFENAC SODIUM
     二氯芬酸钠的合成
短句来源
     Excess supplemental choline for swine
     猪日粮中胆碱过量会影响增重
短句来源
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Objective To establish the drug concentration-time curve of diclofenac choline in rabbits aqueous humor. Methods Twenty-four rabbits was randomly assigned to eight time-groups. 100 LμL of diclofenac choline ( DAC ) drops was topical administrated to the rabbit eyes, and the aqueous humor samples in eight different time-points were taken. High performance liquid chromatograpy with methanol-actonphosphate (25: 25: 50) as liquid phase and Zor bax SBC 18 colorimetric column as solid phase was used to...

Objective To establish the drug concentration-time curve of diclofenac choline in rabbits aqueous humor. Methods Twenty-four rabbits was randomly assigned to eight time-groups. 100 LμL of diclofenac choline ( DAC ) drops was topical administrated to the rabbit eyes, and the aqueous humor samples in eight different time-points were taken. High performance liquid chromatograpy with methanol-actonphosphate (25: 25: 50) as liquid phase and Zor bax SBC 18 colorimetric column as solid phase was used to determine the concentration-time curve of diclofenac choline. Results Diclofenac choline was detected in rabbit aqueous humor only 15 minutes after its topical administration at a single dose of 100 μL. Not interfaring peak for contaminating material was seen. The mean drug concentration-time curve was established by plotting the concentrations of diclofenac choline in aqueous humor vs time. Diclofenac choline in the aqueous humor reached its Cmax at 0. 5 hour after its application and was eliminated completely 12 hours later. Conclusion This drug can act rapidly after its topically administrate and has an acceptable permeation via the cornea.

目的探索双氯芬酸胆碱滴眼液点眼后的房水药代动力学行为。方法取24只家兔,随机平均分成0.25、0.5、0.75、1、2、4、8、12h8个时间组,用微量进样器滴入双氯芬酸钠胆碱(DAC)滴眼液100μL,分别于8个时间点取不少于200μL的房水样品。采用甲醇-乙腈-pH6.4磷酸盐(25:25:50)为流动相,ZorbaxSBC18色谱柱为固定相的高效液相色谱法测定各时间点房水中双氯芬酸胆碱的质量浓度。结果家兔单剂量应用双氯芬酸胆碱滴眼液100μL后,房水中15min后即可检测到药物,且无其他杂质峰干扰,用不同时间点房水中的双氯芬酸胆碱药物质量浓度对时间作图,得其药-时曲线。结论药-时曲线显示,给药后0.5h房水中双氯芬酸胆碱滴跟液质量浓度达到峰值,12h基本代谢完全。该药显效快,并具有良好的角膜渗透性。

 
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