助手标题  
全文文献 工具书 数字 学术定义 翻译助手 学术趋势 更多
查询帮助
意见反馈
   burst release 的翻译结果: 查询用时:0.051秒
图标索引 在分类学科中查询
所有学科
药学
有机化工
更多类别查询

图标索引 历史查询
 

burst release
相关语句
  突释
     The microspheres were smooth and spherical with mean diameter of 41μm, the drug loading of 0.79%, the entrapment efficiency of 79% and the burst release of 28%.
     按优化处方制得的微球表面光滑、圆整,平均粒径41μm,载药量0.79%,包封率79%,突释28%。
短句来源
     The drug release rate was only(18.37)% during the burst release phase and rose to 75.72% at 14d.
     微球体外释药符合Higuichi方程:突释期仅为18.37%,14d后释放度达75.72%。
短句来源
     6 t 1/2 -15.705? 1 ( r =0.997?5). The drug release rate was only 19.26% during the burst release phase and rose to 72.47% at the 11th day.
     微球体外释药规律符合Higuichi方程 :Q =2 5 884 6t1/ 2 - 15 70 5 1(r =0 9975 ) ,突释期内释放度仅为 19 2 6 % ,11d后其释放度达到72 4 7%。
短句来源
     In the drug release test in vitro,the drug release rate was 28.65% during the burst release phase and rose to 77.46% at the end of 12 th day.
     纳米粒体外释药突释期累积释放率为28.65%,12 d后释放率为77.46%。
短句来源
     Results:The average particle size of the NC-PLGA microspheres was 31.3±3.2μm, the drug-loading ratio was 13.7%, and the entrapment efficiency was 89.2%. Studies on the release in vitro showed that nearly on the first tow days initial burst release about 30% could be seen, drug could release slowly in 20 days.
     结果NC-PLGA外观形态为直径31.34±3.2μm的微球,载药率为13.7%,包封率为89.2%,微球体外试验显示前两天有初始突释现象,共释放约30%,药物能够在随后时间内缓慢平稳释放至20天以上。
短句来源
更多       
  “burst release”译为未确定词的双语例句
     The in vitro release kinetics of WO-1 revealed that an effective therapeutic concentration(0.2-0.8 μg/ml) of WO-1 was maintained for 6 days after a high initial burst release.
     生物衍生骨钙/磷比为1.77。 药物释放实验生物衍生骨-WO-1药物缓释系统1d表现为爆发释放,溶液浓度为4.6μg/ml,此后可连续释放6d,浓度维持在0.2~0.8μg/ml。
短句来源
     An initial burst release (33.2%) of the incorporated rhBMP-2 was observed during the first day;
     rhBMP2从支架材料中释放的动力学过程第1天表现为“爆发性”释放(33.2%);
短句来源
     In vitro release test showed a burst release of DGR from microspheres, followed by sustained release of 50% total activity over 15 days.
     DGR微球的体外释放呈现两个时相,15d释放大约DGR总活性的50%。
短句来源
     An initial burst release (30.0%) of the incorporated rhBMP 2 was observed over the first day followed by a sustained release for the remainder, which reached 80.6% at one month.
     rhBMP - 2从支架中释放的动力学过程为第 1天表现为爆发性释放 ( 30 .0 % ) ,以后缓慢持续释放 ,至 1个月左右释放量达 80 .6 % ;
短句来源
     Conclusion: The microcapsule would control the the effect of initial burst release of ASA - PHPA.
     结果:微囊型ASA-PHPA能有效地控制该共价复合体的"爆释"现象。
短句来源
更多       
  相似匹配句对
     Some burst release drug is evident,some has the antigenicity.
     课题研究第一部分:可塑性nano-HA/PHBV-PEG庆大霉素释药系统研制及体内释放实验
短句来源
     NEW RELEASE
     新片推荐
短句来源
     BURST ANGEL
     来自地狱的天使们 爆裂天使
短句来源
     Intelligent Release
     智能脱扣器
短句来源
     STUDIES ON THE PHENOMENON OF INITIAL BURST RELEASE OF ASPIRIN-POLYASARAMIDE CONJUGATE
     阿司匹林─聚天冬酰胺共价复合体“爆释”现象研究
短句来源
查询“burst release”译词为用户自定义的双语例句

    我想查看译文中含有:的双语例句
例句
为了更好的帮助您理解掌握查询词或其译词在地道英语中的实际用法,我们为您准备了出自英文原文的大量英语例句,供您参考。
  burst release
The drug release from RG 502 followed a linear pattern throughout the dissolution without any significant burst release.
      
In contrast, large burst release was observed for polydisperse microspheres produced by a conventional emulsification technique, particularly for microspheres smaller than 25 μm in diameter, which gave 93% burst at 15% loading.
      
The burst release of insulin was high (47%) from batch B and low (5%) from batch A.
      
The smaller the volumes of internal and external aqueous phase, the lower the initial burst release.
      
In phosphate buffer (pH 7.4), microspheres showed an initial burst release of 22% in 1 hour with an additional 28% release in the next 5 hours.
      
更多          


For the purnose of enhancing the the rapeutic index and reducing the toxic effect of chemotherapeuticdrugs,daunomycin-human albumin microspheres(Dau-HA-MS) were prepared,mostly as monodispersedmicrospheres with a mean diameter of 52 ± 16 μm,ranging from 29 to 1 94 μm,being suitable for the use in TAEtherapy. Dau was released effectively in physiologic saline solution from microspheres without burst release. Thespectrophotometric character and cytotoxic effect in vitro of the released Dau were unchanged,the...

For the purnose of enhancing the the rapeutic index and reducing the toxic effect of chemotherapeuticdrugs,daunomycin-human albumin microspheres(Dau-HA-MS) were prepared,mostly as monodispersedmicrospheres with a mean diameter of 52 ± 16 μm,ranging from 29 to 1 94 μm,being suitable for the use in TAEtherapy. Dau was released effectively in physiologic saline solution from microspheres without burst release. Thespectrophotometric character and cytotoxic effect in vitro of the released Dau were unchanged,the originalphysico-chemical and biological properties were retained in the microsphere preparation. It was demonstrated that30% of miee bearing S180 ascites sarcoma treated with intraperitoneal injection of Dau-HA-MS survived 6months longer and more while tumor bearing control mice and Dau treated tumor bearing mice all died in 21 and14 days respectively,showing that Dau-HA-MS were more therapeutically effective and less toxic than Dau. It issuggested that Dau-HA-MS might be used in TAE therapy for human liver cancer.

为了提高化疗药物的治疗指数和降低其毒性,制备了柔红霉素-人血清白蛋白微球(Dau-HA-MS),绝大多数为单分散相微球,平均直径56±16μm,范围为29─194μm,适用于导管动脉栓塞治疗。Dau-HA~MS在生理盐水中能有效释放Dau,但无爆发释放的缺点。释放的Dau的光谱特性和体外细胞毒效应与原药相比无变化,表明Dau通过微球制备仍保留原有的理化及生物学特性。实验表明经腹腔注射Dau-HA-MS使30%的S180腹水癌小鼠活存超过6个月,而肿瘤对照组及Dau治疗肿瘤组均分别在21d和14d全部死亡,说明Dau-HA-MS有较好的疗效及较低的毒性,提示Dau-HA-MS有可能用于人肝癌的导管动脉栓塞治疗,有进一步研究的价值。

OBJECTIVE: To improve drug burst release and stagnant release of magnetic cisplatin microspheres (MCM). METHODS: Preparing MCM by different crafts and determining drug in vivo and in vitro release. RESULTS: The prepared MCM could achieve controlled release effectively when the ratio of hydrophobic skeleton materials to crosslink coincident materials with hydrolytic bond in the polymeric substratum materials was seven to three, the stirring speed was 1 500 r·min-1, and the shaping...

OBJECTIVE: To improve drug burst release and stagnant release of magnetic cisplatin microspheres (MCM). METHODS: Preparing MCM by different crafts and determining drug in vivo and in vitro release. RESULTS: The prepared MCM could achieve controlled release effectively when the ratio of hydrophobic skeleton materials to crosslink coincident materials with hydrolytic bond in the polymeric substratum materials was seven to three, the stirring speed was 1 500 r·min-1, and the shaping temperature was 20 ℃. CONCLUSION: It is important to develop magnetic microspheres for treating malignant tumours.

目的:改善磁性顺铂微球的药物突释和滞释,实现控释。方法:用不同的工艺制备磁性顺铂微球并进行体外、体内药物释放的测定。结果:当高分子骨架材料中,疏水性纤维多糖含水解键的苯酐聚合物=7∶3,搅拌速度1500r·min-1,成型温度20℃时,制备的磁性顺铂微球具有较好的控释特性。结论:对开发磁性微球和导向治疗恶性肿瘤有实际意义

The pharmacokinetics of Sino - CLa implants which were removed" burst release" were studied in the Chinese voluntary women for five years. The plasma level of levonorgestral (LNG) in each implant user has been measured by RIA. The result indicated that a steady - state LNG plasma level has been maintained throughout the course of 5 years application. The peak concentration of LNG was reached after 24 hours of the insertion of Sino - CLa implant which was fourflod higher than that of the 5th years. The...

The pharmacokinetics of Sino - CLa implants which were removed" burst release" were studied in the Chinese voluntary women for five years. The plasma level of levonorgestral (LNG) in each implant user has been measured by RIA. The result indicated that a steady - state LNG plasma level has been maintained throughout the course of 5 years application. The peak concentration of LNG was reached after 24 hours of the insertion of Sino - CLa implant which was fourflod higher than that of the 5th years. The plasma level of LNG was 0.96 ± 0.41nmol/L (mean ± se) at the end of 5th and this concentration has been proven highly effective for contraception. The result of the drug release rate in vivo was unified with the plasma concene-tration fluctuation the amount of LNG released from implant was 43. 96μg/d during 1 -5 years. Longterm implant through five years. The LNG of remaining in implants are 52.13% of total imply weigh.The elimination T1/2 was 44.55hr and the plasma clearance was 334.0L/d after implants removed.

对10例埋植国产去除爆破效应(本文简称除爆)的CLa皮下埋植剂(左旋18-甲基炔诺酮,本文简称皮埋剂)的妇女进行5年血药水平、释药速率及药物清除等药代动力学观察,结果显示:埋植除爆CLa皮埋剂后,24h血药水平是稳态水平的4.5倍左右,5年时平均血药水平为0.96±0.41nmol/L,释药速率36.21μg/d,足以达到避孕有效浓度,埋植除爆CLa皮埋剂后,各个时期平均血药水平基本恒定,用药5年时平均血药水平比用药早期略低,释药速率与血药浓度变化趋势相似。1~5年平均释药速率为43.96μg/d。经过5年埋植,埋植剂内剩余LNG为总含量的52.13%。取出埋植剂后,消除半衰期为44.55h,廓清率为334.00L/d。

 
<< 更多相关文摘    
图标索引 相关查询

 


 
CNKI小工具
在英文学术搜索中查有关burst release的内容
在知识搜索中查有关burst release的内容
在数字搜索中查有关burst release的内容
在概念知识元中查有关burst release的内容
在学术趋势中查有关burst release的内容
 
 

CNKI主页设CNKI翻译助手为主页 | 收藏CNKI翻译助手 | 广告服务 | 英文学术搜索
版权图标  2008 CNKI-中国知网
京ICP证040431号 互联网出版许可证 新出网证(京)字008号
北京市公安局海淀分局 备案号:110 1081725
版权图标 2008中国知网(cnki) 中国学术期刊(光盘版)电子杂志社