The HO-8910 cell concentration of 4.5×106/100 μL was selected, injected into nude mice intradermally(group C),back(group D) and subcutaneous layer of forelimb axillary fossa(group E).
Extrapulmonary manifestations (metastasis) included 19 cases (44.2%) of lymph nodes to the supraclavicular region, axillary fossa, and post-peritoneal region, 15 cases (34.9%) to the pleura, 9 cases (20.9%) to the bones, 6 cases (14.0%) to the liver, 3 cases (7.0%) to the pericardium, and 3 cases (7.0%) to the brain.
Follow-up observations for a median of 54 months (range,2 ～ 84 months) revealed a local recurrence rate of 2 7% ( 4/148 ;3 patients in breast and 1 patient in axillary fossa).
Eight days after being inoculated with allogenic hepatoma cells(Hca-F25) into the subcutaneos tissue of the right axillary fossa, the mice(group B)were randomly divided into four groups(B1, n=6; B2, n=5; B3, n=3; B4, n=3). Group B1 and group B3 received a single dose of cyclophosphamide(150mg/kg, intraperitoneally).
Methods Osteosarcoma model of nude mouse was made with MG-63 cells injected into axillary fossa. Forty -eight nude mice were divided randomly into 6 groups: (1) PBS control group;
The expression of NF-κB p50 in BC was not related to tumor size, histological grade and progesterone receptor (PR)(P > 0.05), but to the lymphnode metastasis of axillary fossa, estrogen receptor (ER)(P < 0.05).
Methods After the sequence of EScDNA in the pSecTagA-EScDNA was identified correctly, human umbilical vein endothelial cells (ECV-304) were transfected with pSecTagA-EScDNA and pSecTagA by the lipofection method to assess the suppressive effect on the growth of ECV-304. Rat C6 glioma models were established by subcutaneously implanting C6 cells in axillary fossa.
Previous light-microscopic studies have shown a unique population of mast cells in lymphatic sinuses of lymph nodes located in the head, neck, axillary fossa and inguinal region of the opossum.
She first noticed the mass as a small swelling in her left axillary fossa during the 7th month of her pregnancy.
The present paper deals with a new antiarch——Procondylolepis qujingensis gen.et sp.nov.The specimens,including some detached shoulder joints,several pectoralfins and a few isolated pectoral fin plates were collected from the Lower Devonianof Cuifengshan,Qujing,Yunnan in the past few years.Associated with this antiarchare Yunnanolepis parvus and Phymolepis cuifengshanensis etc.The new genus is char-acterized by the presence of a primitive brachial process at the base of axillary fossa,by its rather complicated...
The present paper deals with a new antiarch——Procondylolepis qujingensis gen.et sp.nov.The specimens,including some detached shoulder joints,several pectoralfins and a few isolated pectoral fin plates were collected from the Lower Devonianof Cuifengshan,Qujing,Yunnan in the past few years.Associated with this antiarchare Yunnanolepis parvus and Phymolepis cuifengshanensis etc.The new genus is char-acterized by the presence of a primitive brachial process at the base of axillary fossa,by its rather complicated axillary fossa margin and its small articular area of pec-toral fin.It differs from Yunnanolepis and Phymolepis in having a V-shaped bonyplate representing an early stage of brachial process at the base of axillary fossa,inhaving the separate dorsal and ventral fossae which are articulated with pectoral finat margin of axillary fossa,and in presence of a quite smooth articulated surfaceat the medial margin of the axillary fossa.The pectoral fin is small,short unjointed,made up of four longitudinal series ofplates,and basically similar to that of Remigolepis of Late Devonian in pattern.Thenew form.however,differs distinctly from Remigolepis in some significant morphologicalcharacters:absence of a helmetlike brachial process;having a very small and convexarticular area of pectoral fin articulated with shoulder girdle;thick lateral and flatmedial margin of pectoral fin,which might imply the difference of motive means.Itis very significant for understanding the development of the shoulder girdle and pec-toral fin in various evolutionary stages and the changes in their evolutionary history,as the Antiarchi is considered to be one of the highly specialized form among the ver-tebrates in regards of its shoulder girdle and pectoral fin.The discovery of Procondylolepis(gen.nov.)has provided new evidences for thestudy of the origin,evolution and classification of Antiarchi.On the basis of characters of the shoulder joint and pectoral fin of Procondylo-lepis,it leads to the following conclusions:1.The pectoral fin armour appeared earlier than brachial process in the evolu-tionary history of the Antiarchi.2.Procondylolepis gen.nov.is a transitional form representing a stage of An-tiarchi evolution which intermediated between the non-brachial process form,as Yun-nanolepiformes in the Early Devonian and the brachial process form,as those in theMiddle and Late Devonian ages. 3.Among the so far known antiarchs of Early Devonian,the shoulder girdle ofProcondylolepis gen.nov.is close mostly to those of ancestoral antiarchs of Middleand Late Devonian morphologically.All the known antiarchs of Middle and LateDevonian may be descended from some forms related to Procondylolepis.4.The unjointed pectoral fin of antiarchs is a primitive characteristic.thedorsal articular plate of the antiarchs known from Middle and Late Devonian whichhas long been thought to be the first dorsal central plate(Cd_1)should be the firstlateral marginal plate(Ml_1).5.The motion pattern of the pectoral fin in Procondylolepis gen.nov.is differentfrom those of antiarchs of Middle and Late Devonian.6.Antiarchi is suggested to be classified into two Superorder,Abrachicondyliaand Brachicondylia.Procondylolepiformes(ord.nov.)is proposed under the Brachi-condylia.
BALB/c nude mice(NM)bearing human nasopharyngeal carcinoma(NPC)was reproduced byhypodermic implantation of human CNE-2 cells into right-side of axillary fossa. The alteration of plasmicmalondialdehyde(MDA) content and superoxide dismutase(SOD)activity were monitored in latent,early,middle and late phases(at 5, 10, 20 and 30 days followed inoculation of CNE-2 cells)of NM bearing humanNPC respectively in comparison with that of control group.Results indicated that in latent phase plasmicMDA content (7.51...
BALB/c nude mice(NM)bearing human nasopharyngeal carcinoma(NPC)was reproduced byhypodermic implantation of human CNE-2 cells into right-side of axillary fossa. The alteration of plasmicmalondialdehyde(MDA) content and superoxide dismutase(SOD)activity were monitored in latent,early,middle and late phases(at 5, 10, 20 and 30 days followed inoculation of CNE-2 cells)of NM bearing humanNPC respectively in comparison with that of control group.Results indicated that in latent phase plasmicMDA content (7.51 nmol/ml)increased sharply and was at its peak in early phase(20. 67 nmol/ml).Thiswas followed by a steady decline in its content, but in late phase its content(6.19 nmol/ml)still increasedmore markedly than that of the control group (4. 54nmol/ml).while plasmic MnSOD activity in middle orlate phase(27. 73 or 19. 97 nu/ml)decreased sharply in comparison with the control group (70. 21 nu/ml).These results suggestel that there is a relationship between plasmic MDA content or SOD activity and NPC.
rats were divided at random into 3(A. b.c) groups, and given abdominal anesthesia by injecting urethan(1 g/kg).Dual-needle electrode was located in the biceps femora to record myoeletricity; plate electrode was located subcutaneously in axillary fossa to record myocardioelectricity; the amplitude and frequency of myocardioelectricity,the threshold and latency of flexion reflex were recorded automatically through the biological signal translating system (SMUPPC);quantitative analysis was performed.43 μg/kg...
rats were divided at random into 3(A. b.c) groups, and given abdominal anesthesia by injecting urethan(1 g/kg).Dual-needle electrode was located in the biceps femora to record myoeletricity; plate electrode was located subcutaneously in axillary fossa to record myocardioelectricity; the amplitude and frequency of myocardioelectricity,the threshold and latency of flexion reflex were recorded automatically through the biological signal translating system (SMUPPC);quantitative analysis was performed.43 μg/kg AFSVC-Ⅱ were injected through the tail vein in Group A;65 μg/kg in Group B; 130 μg/kg in Group C;the contents of injection were0.3ml. Before and after AFSVC-Ⅱ was injected, the above physiological standards were measured separately (the measuring interval was 10 min,observation was stopt in 80 min).The results demonstrated that 43～65 μg/kg AFSVC-Ⅱ injected via tail vein had no eminent effects on the amplitude of myocardioelectricity, while 130 μg/kg AFSVC-Ⅱ could markedly decrease it during 10 to 30 min; 43～65 μg/kg AFSVC-Ⅱ had no eminent effects on the flexion reflex,whereas 130 μg/kg AFSVC-Ⅱ could markedly depress the neuromuscular excitability and prolong the nerve conducting speed. The experiment provided new theoretical proof of scorpion venom binding sodium channel.
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