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morphine
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  吗啡
     The study on the mechanism of oxytocin synthesis and release modulated by morphine in the rat,and the Functional implication of GIRK
     吗啡调节大鼠催产素合成与释放的机制及GIRK在吗啡效应中作用的研究
短句来源
     Gene Expression and Synaptic Interface Structure in Specific Brain Regions of Morphine Dependent Rats and Related Influences of Dizocilpine
     吗啡依赖大鼠部分脑区基因表达、突触结构改变及其地卓西平的影响
短句来源
     Experimental Studies on Neurobiological Changes of Heroin, Morphine and Pethidine Drug Abuse in Rats
     海洛因、吗啡、度冷丁药物滥用神经生物学变化的实验性研究
短句来源
     cDNA Cloning and Identification of Hippocampal Differentially Expressed Genes Correlated to Morphine Dependent Memory and Application Study in Rats
     大鼠海马与吗啡依赖记忆相关差异表达基因cDNA的克隆、鉴定及应用研究
短句来源
     Regulation of GRK2, GRK5 and JNK3 Gene Expression in Rat Brain by Morphine
     吗啡对GRK2、GRK5和JNK3基因在大鼠脑内表达调控的研究
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  “morphine”译为未确定词的双语例句
     The infusing background of group T was tramadol 0.2mg·kg-1·h-1+ fentanyl 0.1μg·kg-1·h-1 and single dose was morphine 5 mg+ fentanyl 5 μg.
     曲马多组(T组)背景输注曲马多0.2mg·kg-1·h-1+芬太尼0.1μg·kg-1·h-1,单次给药量曲马多5mg+芬太尼5μg;
短句来源
     Results:The average recovery of morphine was98.53%. RSD was2.4%.
     结果 :平均回收率为98.53%,RSD2.4% ;
短句来源
     The prescription of PCEA of group L and R were 2 g/L levobupivacaine+0.04 g/L morphine(Mor)+0.02 g/L droperidol(Dro) and 2 g/L ropivacaine+0.04 g/L Mor+0.02 g/L Dro.
     R组(n=30):镇痛药为2g/L罗哌卡因(Rop)+0.04g/LMor+0.02g/LDro,PCEA方法同L组;
短句来源
     Conclusion:con-G,con-GS~ 16 Y and con-R(1-17) can significantly reduce morphine withdrawal symptoms.
     结论:con-G、con-G[S16Y]〗和con-R(1-17)对抑制小鼠的戒断症状非常有效。
短句来源
     Compared with con-R(1-17),the higher inhibitory activities of con-G and con-GS~ 16 Y on naloxone-induced withdrawal jumping in morphine dependent mice arise from their higher selectivity of NR2B subunit of NMDA receptor.
     相对于con-R(1-17),con-G和con-G[S16Y]〗对小鼠的戒断症状的抑制作用更强,这是由于con-G、con-G[S16Y]〗对NMDA受体NR2B亚基的选择性更高。
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  相似匹配句对
     Morphine Immunoassay
     吗啡的免疫测定
短句来源
     (2) morphine group (M);
     吗啡组(M组),鞘内应用吗啡20 μg;
短句来源
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  morphine
Gas Chromatography-Mass Spectrometry Determination of Morphine and Codeine in Blood as Their Propionic Esters
      
A gas-chromatographic separation procedure with mass-spectrometric detection was developed for the detection of opiates in whole blood and the quantitative determination of morphine and codeine as their propionic esters.
      
The detection limit for morphine and codeine in blood was 0.02 μg/mL.
      
An express morphine assay in aqueous samples by immunochromatography using monoclonal antibodies labeled with colloidal gold
      
A simple and accessible express method was developed for the detection of morphine in aqueous samples using competitive immunochromatography.
      
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Corydalis B (dl-tetrahydropalmatine) and L, isolated from Corydalis ambigua Cham. et Sch. by Prof. T. Q. Chou, were found to possess marked analgesic activity and less tolerance than morphine. In the present work their effects on blood pressure, cardiac rhythm and respiration were studied. The blood pressure of the carotid artery was recorded and EKG of lead Ⅱ was taken in anesthetized cats. The respiratory minute volume was measured in unanesthetized rabbits. The results were as follows: Corydalis B...

Corydalis B (dl-tetrahydropalmatine) and L, isolated from Corydalis ambigua Cham. et Sch. by Prof. T. Q. Chou, were found to possess marked analgesic activity and less tolerance than morphine. In the present work their effects on blood pressure, cardiac rhythm and respiration were studied. The blood pressure of the carotid artery was recorded and EKG of lead Ⅱ was taken in anesthetized cats. The respiratory minute volume was measured in unanesthetized rabbits. The results were as follows: Corydalis B 40 mg/kg (approximately twice the analgesic dosage) produced bradycardia and a gradual decrease of blood pressure by 20--40 mm Hg which slowly recovered within 1 hour. There was no significant change in EKG. Intravenous injection of 60 mg/kg gave a temporary increase of respiratory minute volume by 130--165 ml (26--37% above the original level) for 1--2 minutes and then a decrease of 85—320 ml/min (20--48% bolow the original level). The respiratory volume gradually returned to the original level in 1/2-1 hour. The respiratory rate showed little change. Corydalis L 30 mg/kg (approximately twice the analgesic dosage) rendered a lowering of blood pressure by 30--60 mm Hg within 5--10 minutes, accompanied by bradycardia and inverted T-wave. Respiratory minute volume gradually increased by 170—300 ml (30—60% above the original level) for 1--1 1/2 hours, but the respiratory rate showed no significant change.

1.給麻醉猫靜脉內慢慢注射延胡索素乙40毫克/千克(相当2倍鎮痛有效剂量)时,血压略降,心跳变慢,心脏功能無明显变化.正常家兔靜脉注射乙素20或40毫克/千克时,呼吸短时兴奋;剂量增至60毫克/千克(相当3倍鎮痛有效剂量)时,呼吸有抑制. 2.麻醉猫靜脉內慢慢注射延胡索素丑30毫克/千克(相当鎮痛有效剂量的2倍),血压略降,心跳变慢,心电圖的T波有倒置現象。正常家兎靜脉注射丑素30毫克/千克时,对呼吸無抑制,而有兴奋現象。

The Pellagri's reaction has been known to be a specific and sensitive color reaction for morphine and its derivatives. However, because of the lack of mastering the proper experimental conditions, this reaction always fails to give consistent results and consequently can only be applied as a qualitative but not a quantitative method. According to the following experimental condition, we have succeeded to determine morphine colorimetrically with good reproducibility and to raise up the identification...

The Pellagri's reaction has been known to be a specific and sensitive color reaction for morphine and its derivatives. However, because of the lack of mastering the proper experimental conditions, this reaction always fails to give consistent results and consequently can only be applied as a qualitative but not a quantitative method. According to the following experimental condition, we have succeeded to determine morphine colorimetrically with good reproducibility and to raise up the identification limit to 1 γ morphine base. After evaporating the aqueous solution of morphine hydrochloride or chloroform extract to dryness on a water bath, add 3 drops of HCI-H_2SO_4 (10:1) and heat for 30 minutes. Remove it from the water bath and add 6 drops of pH 7 buffer solution (KH_2PO_4-NaOH), 8 drops of 10% NaHCO_3 solution and 3 drops of 2% HIO_3 solution. Heat for 1/2 minute over water bath, then add 5 ml of water and heat for another 1/2 minute. Extract with 5 ml of n-butyl alcohol, and use the organic layer for the quantitative determination by measuring its extinction at 595 mμ or using a red brown filter instead. For the qualitative purpose, the solution to which HIO_3 has been added, is heated for 1 minute on the water bath, transferred to a test tube (5×70 mm), and is shaken with 1-2 drops of n-butyl alcohol. In the presence of morphine and its derivatives the alcoholic layer should be bluish green.

本文对Pellagri氏反应作了較全面的探討与改进,得出: 1.最合适的脱水剂是HCl-H_2SO_4(1ml:2滴),加酸后在水浴上蒸發半小时脫水,然后用KH_2PO_4-NaOH緩冲溶液及NaHCO_3溶液中和到PH7左右时所得結果最好,氧化剂以碘酸溶液为最佳。 2.反应产物可用有机溶剂抽出,其中正丁醇的抽出力最强,使反应的鑑识限度提高为1γ嗎啡鹽基. 3.依照本文条件試驗,反应产物的水溶液,正丁醇抽出液及苯抽出液都符合Beor氏定律(圖2),可用作嗎啡类化合物的比色定量(表1)。

Intraperitoneal injection of Sabianine,A an alkaloid isolated from the stem of Sabia japonica (Qingfengdung),at A dose of 50 mg/kg in mice raised the pain threshold significantly.The po- tency ratio of Sabianine A and morphine hydrochloride was about 1:2.5. In addition,Sabianine a administered intraperitoneally at a dosage of 60 mg/kg not only lessened the severity of the swelling of the ankle joint of the rats hind leg caused by the injection of formalin or egg-white,but also rendered the swelling of...

Intraperitoneal injection of Sabianine,A an alkaloid isolated from the stem of Sabia japonica (Qingfengdung),at A dose of 50 mg/kg in mice raised the pain threshold significantly.The po- tency ratio of Sabianine A and morphine hydrochloride was about 1:2.5. In addition,Sabianine a administered intraperitoneally at a dosage of 60 mg/kg not only lessened the severity of the swelling of the ankle joint of the rats hind leg caused by the injection of formalin or egg-white,but also rendered the swelling of the ankle joint disappear more rapidly. The LD_(50) of Sabianine for mice A administered intraperitoneally was 285±29 mg/kg.

一、清风藤硷甲50及100毫克/公斤给小白鼠腹腔注射能显著提高动物对热刺激的痛阈,其作用强度与吗啡比较约为1:2.5.二、清风藤硷甲60毫克/公斤腹腔注射对大白鼠甲醛性及蛋清性“关节炎”,无论预先给药或与产生”关节炎”同时给药,不但可使关节肿胀程度较对照组显著为少,且消退亦速.三、清风藤硷甲腹腔注射对小白鼠之半数致死量为285±29毫克/公斤.

 
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