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      耐药肿瘤     
相关语句
  drug resistant tumor
     Effect of the expression of integrin β-1 on apoptosis of drug resistant tumor cells
     耐药肿瘤细胞β-1整合素表达及对细胞凋亡的影响研究
短句来源
     Antisense MDR oligonucleotide combined with chemotherapy to inhibit drug resistant tumor cell growth
     反义MDR寡核苷酸联合化疗药物抑制耐药肿瘤细胞
短句来源
     The first section is about studies on the in vitro and in vivo anti-tumor activity of PH Ⅱ -7 and it's possible mechanisms, the second section is about identification and validation of drug resistance-related gene candidates with cDNA microarray, which will provide potential new targets for the diagnosis and therapy of clinical drug resistant tumor.
     本文首先对抗耐药肿瘤新药PHⅡ-7的体内体外活性及其机制进行研究,为PHⅡ-7的开发和临床应用打下基础:另外利用cDNA array等技术筛选出几个可能的耐药相关新基因,为临床耐药肿瘤的诊断和治疗提供新靶点。
短句来源
     Objective To observe the expression of adhesion molecular integrin β 1 in drug resistant tumor cells and its influence on programmed cell death so as to find a possible way to invert drug resistance.
     目的 探讨耐药肿瘤粘附分子 β 1整合素的表达以及其对细胞凋亡的影响 ,并寻找逆转耐药的途径。
短句来源
  multidrug resistant tumor
     Conclusion The successful construction of expressive vectors containing MDR1 promoter provides an experimental basis for targeted gene therapy to the multidrug resistant tumor cells.
     结论成功构建了MDR1启动子高表达载体,为靶向治疗耐药肿瘤构建载体提供了实验基础。
短句来源
     Results PHⅡ-7inhibited the proliferation of various human tumor cells derived from different tumor cell lines. The IC 50 values varied from0.34~18.61μmol/L. Especially,PHⅡ-7had strong inhibitory effect on multidrug resistant tumor cells,whereas adriamycin(ADR)was resistant.
     结果PHⅡ-7对多种人肿瘤细胞的生长有抑制作用,IC50为0.34~18.61μmol/L,更为突出的是,对于MDR类抗肿瘤药无效的多药耐药肿瘤细胞,PHⅡ-7同样具有生长抑制作用;
短句来源
     CDTK. provide an experimental basis for targeted gene therapy to the multidrug resistant tumor cells.
     CDTK,为今后靶向治疗耐药肿瘤构建载体提供了实验基础。
短句来源
     Preliminary Studies on the Mechanisms of a New Anti-tumor Agent PHⅡ-7 with Special Preference to Multidrug Resistant Tumor Cells
     抗耐药肿瘤新药PHⅡ-7作用机制的初步研究
短句来源
     coli, and then its effect on multidrug resistant tumor cells has been studied.
     第二部分克隆表达了hTNF-α并研究了它对耐药肿瘤细胞的逆转作用。
短句来源
更多       
  drug-resistant tumor
     dah, C. foe, C. dah 1-3 and Cfoe-1 on all tested neoplastic cell lines revealed that they were effective on both drug-resistant tumor and drug-sensitive tumor.
     结果表明,UA、BA、C.dah、C.foe、C.dah 1-3和C.foe-1具有良好的细胞毒性和相对选择性,并且对耐药肿瘤细胞同样有效,是较为理想的细胞毒制剂。
短句来源
     In Vitro Research on the Effects Against Drug-Resistant Tumor Cells of Nine Active Components of Traditional Chinese Drugs
     九种中药活性成分抗耐药肿瘤细胞体外研究
短句来源
     TTD may act by means of suppressing the function of the P-170 glycoprotein in drug-resistant tumor cells.
     推测TTD可能是通过抑制耐药肿瘤细胞膜上P-170糖蛋白的功能而起作用的。
短句来源
     Conclusions: p14 ARF can suppress the growth of the p53 positive tumor cell lines in a p53-relevant manner, while in the p53 negative, drug-resistant tumor cells, p14 ARF has strong inhibitory effect, indicating the inhibitory effect of p14 ARF on growth of drug-resistant tumor cells is independent on p53, at least in KB-v200 and MCF7/ADR drug-resistant cells.
     结论 :p14 ARF能明显抑制 p5 3阳性肿瘤细胞的生长 ,具有 p5 3相关性 ; 然而 p14 ARF对 p5 3阴性的耐药肿瘤细胞却具有强烈的抑制作用 ,由此提示 :p14 ARF抑制耐药肿瘤细胞的生长是 p5 3非依赖性的
短句来源
     Objective To investigate the inhibition of drug-resistant tumor growth by antisense MDR oligonucleotide combined with chemotherapy.
     目的 探讨反义MDR核酸技术联合化疗对耐药肿瘤细胞的生长抑制作用。
短句来源
  drug fast cancer
     Conclutions TS and p16 double promoters are capable of inducting TK target killing of 5 FU drug fast cancer cells, thus protecting normal cells and improving safety of gene therapy.
     结论 TS和p1 6双启动子可引导TK基因靶向性杀伤 5 FU耐药肿瘤细胞 ,保护肌体正常细胞 ,提高自杀基因治疗的安全性
短句来源
     Objective To study target killing of 5 FU drug fast cancer cells with thymidylate synthase (TS) and p16 gene promoters inducting TK gene expression.
     目的 探讨胸苷酸合成酶 (TS)基因启动子和p1 6基因启动子引导胸苷激酶 (TK)自杀基因靶向杀伤 5 FU耐药肿瘤细胞的作用。
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      drug resistant tumor
    We have shown that neither great increase in the level of YB-1 mRNA nor substantial increase in the number of cells with nuclear localization of YB-1 are obligatory traits of drug resistant tumor cell populations.
    例句来源      
    Our data suggest that although YB-1 regulates several MDR genes, it could not be regarded as a global marker of already formed drug resistant tumor cell populations.
    例句来源      
    This method can also be used to screen drugs which may block efflux of a chemotherpeutic drug and thus increase chemosensitivity of a drug resistant tumor.
    例句来源      
    Anexperimental anti-cancer drug, SH 30demonstrated highly selective and potentcytotoxic activity against a number ofmulti-drug resistant tumor cell lines in vitro.
    例句来源      
    Novel agents that can kill multi-drug resistant tumor cells and reach tumor cells at distant sites in the brain are needed.
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      multidrug resistant tumor
    Intracellular localization and content of YB-1 protein in multidrug resistant tumor cells
    例句来源      
    The unresponsiveness of multidrug resistant tumor cells to antineoplastic chemotherapy is often associated with reduced cellular drug accumulation accomplished by overexpressed transport molecules.
    例句来源      
    Studies in multidrug resistant tumor models confirm P-gp as the in vivo target of PSC-833 and demonstrate the ability of PSC-833 to reverse MDR leukemias and solid tumors in mice.
    例句来源      
    Mitochondrial alterations induced by serum amine oxidase and spermine on human multidrug resistant tumor cells
    例句来源      
    Current research efforts are focused on the development of agents which resensitize multidrug resistant tumor cells to chemotherapeutic drugs.
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      drug-resistant tumor
    The inhibition of these anti-apoptotic gene products by rituximab sensitizes drug-resistant tumor cells to apoptosis induced by a variety of cytotoxic chemotherapeutic drugs.
    例句来源      
    Cure of mice bearing a late-stage, highly metastatic, drug-resistant tumor by adoptive chemoimmunotherapy
    例句来源      
    The data do not demonstrate a correlation between the immunogenic properties of drug-resistant tumor cells and the expression of P-glycoprotein.
    例句来源      
    All pleiotropic (PDR) drug-resistant tumor sublines had decreased membrane potentials (membrane depolarized) compared with their corresponding drug-sensitive parental tumors.
    例句来源      
    Furthermore, BN 58705 is shown to be cytotoxic against several drug-resistant tumor cell lines.
    例句来源      
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