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nimodipine injection
相关语句
  尼莫地平注射液
     Effects of nimodipine injection on expressions of hippocampal bcl-2 and bax mRNA after cardiopulmonary bypass in rats
     尼莫地平注射液对大鼠体外循环后海马bcl-2及baxm RNA表达的影响
短句来源
     Conclusion Nimodipine injection has a good effect on the prevention of DCVS after SAH.
     结论尼莫地平注射液预防SAH后DCVS疗效确切。
短句来源
     Methods 65 patients with AD were randomly divided into two groups:Nimodipine group (n=32), treated with Nimodipine injection;
     方法将65例AD患者随机分成两组,尼莫地平治疗组(尼莫地平组,32例):尼莫地平注射液治疗;
短句来源
     All patients accepted therapy before 72 h after the onset of the attack. The patients of control group accepted conventional therapy (dehydration, hemostasis), therapy group accepted conventional therapy and nimodipine injection 10 mg in 50 mL, iv drip, qd×14 d.
     2组均于发病72h内接受治疗,对照组用脱水、止血等常规疗法,尼莫地平组在常规疗法基础上加用尼莫地平注射液50mL(含10mg),静脉滴注,qd×14d。
短句来源
     Methods 120 patients with SAH were randomly divided into case group(70 patients) and control group(50 patients). The patients of case group were accepted both routine therapy just as control group and nimodipine injection 10mg/50 ml,ivbydrip,then,nimodipine tablet 30mg,po.
     方法 12 0例SAH病人随机分为治疗组 70例和对照组 5 0例 ,治疗组在与对照组相同的常规治疗基础上加用尼莫地平注射液 10mg/ 5 0ml,静脉滴注 ,然后改为尼莫地平片 3 0mg ,口服。
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  尼莫地平注射剂
     Investigation on Nimodipine Injection
     尼莫地平注射剂的研究
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  “nimodipine injection”译为未确定词的双语例句
     Results of the study indicated that there is no significant difference in stability of domestic and imported nimodipine injection with an average relative variation of -1.04%.
     结果表明,国产与进口注射液的尼莫地平稳定性总体上无显著性差异; 然而,国产比进口注射液的尼莫地平稳定性要略差一些,这种差别体现在平均相对差值为-1.04%;
短句来源
     METHODS: The experiment was conducted at the Center Laboratory of Dalian Medical University in July 2004. Totally 120 male SD rats were randomly divided into 3 groups:①Nimodipine group (n=50): 50 μL autologous femoral arterial blood was injected into caudate nucleus to duplicate ICH models, which were instantly given 1.6 mg/kg (8 μL/g) nimodipine injection intraperitoneally, once a day.
     方法:实验于2004-07在大连医科大学中心实验室进行。 取120只SD雄性大鼠随机分为3组:①尼莫地平组(n=50):尾壳核注射自体股动脉血50μL复制脑出血模型,造模即刻腹腔注射尼莫地平1.6mg/kg(即8μL/g),以后每天1次。
短句来源
     METHODS The guinea pigs were randomly divided into 4 groups: dexamethasone injection ischemia and nimodipine injection reperfusion group (group A), nimodipine and dexamethasone injection reperfusion (group B), nimodipine injection reperfusion group (group C), and saline injection reperfusion group (group D).
     方法随机将豚鼠分为4组:地塞米松预处理再灌注应用尼莫地平组(A组)、再灌注应用尼莫地平及地塞米松组(B组)、再灌注应用尼莫地平组(C组)、再灌注对照组(D组)。
短句来源
     Comparative Effects of Tetramethylpyrazine(TMP)and Nimodipine Injection on Cerbral Circulation in Anesthetized Rabbits
     川芎嗪注射剂和尼莫地平对兔脑循环的作用
短句来源
     After 5 minutes reperfusion, the pigs were divided randomly into three groups: the Nimodipine injection (Nim, 0. 2mg/kg), the Shenmai injection (Sm, 1ml/kg) and the control physiological saline. We studied the neuroprotective effects of Nim and SM against transient cerebral ischemia/reperfusion injury.
     制成上述急性完全性脑缺血模型5min后,分三组分别给予尼莫地平(0.2mg/kg)、参麦注射液(1ml/kg)及等量生理盐水静滴,比较尼莫地平、参麦注射液对脑缺血再灌流损伤的复苏效应。
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Nimodipine injection and its stability was studied. The preparation was deternimed by cafculative and deteered by ?? Itwas very stable when heated and unstable under light. under sunlight. it could be deseribed by apparent ?rst order kincies.its reaction rate constant in normal vials was three times higher than that in brown vials.

本文对尼莫地平注射液及其稳定性进行了研究,应用联立方程分光光度法对其进行含量测定,并用薄层层析对其进行检查。其中加入分解液和不加分解液的回收率分别为100.04%(CV=1.62%)和100.40%(CV=0.46%)。本品对热非常稳定,而对光敏感,在日光下,其光解反应为伪一级反应,而采用棕色安瓿包装可延缓尼莫地平的分解,增加本制剂的稳定性。

Transient cerebral ischemia/reperfusion injury in pig whose EEG amplitude became flattened and body presented convulsions was rpoduced by 10 minutes occluding bilateral common carotid and cerebrospinal arteries simutanously with femoral arteric hemorrhagic hypotension to 50% of its original. After 5 minutes reperfusion, the pigs were divided randomly into three groups: the Nimodipine injection (Nim, 0. 2mg/kg), the Shenmai injection (Sm, 1ml/kg) and the control physiological saline. We studied the...

Transient cerebral ischemia/reperfusion injury in pig whose EEG amplitude became flattened and body presented convulsions was rpoduced by 10 minutes occluding bilateral common carotid and cerebrospinal arteries simutanously with femoral arteric hemorrhagic hypotension to 50% of its original. After 5 minutes reperfusion, the pigs were divided randomly into three groups: the Nimodipine injection (Nim, 0. 2mg/kg), the Shenmai injection (Sm, 1ml/kg) and the control physiological saline. We studied the neuroprotective effects of Nim and SM against transient cerebral ischemia/reperfusion injury. The results showed that Nim remarkably quickened the recovery of EEG amplitude and decreased the abnormal rate of EEG (P<0. 01),Sm had similar effects,but is weaker than that of the Nim (P<0. 05). Both Nim and Sm could significantly inhibit the increase of cAMP contents in cerebrospinal fluid after reper fusion (P<0. 05). They also reduced the edema and injury to cerebro-cortical tissues after reperfusion. All above mentioned suggested that both Nim, which is a calcium antagonist and Sm, which is a free radical scavenger had neuroprotective effects against transient cerebral ischemia and reperfusion injury in pigs.

猪经股动脉放血降压至术前的50%,同时阻断其双侧颈总动脉和推动脉。10min后出现平坦脑电图(EEG)且伴随全身抽搐。制成上述急性完全性脑缺血模型5min后,分三组分别给予尼莫地平(0.2mg/kg)、参麦注射液(1ml/kg)及等量生理盐水静滴,比较尼莫地平、参麦注射液对脑缺血再灌流损伤的复苏效应。与对照组相比,结果表现为尼莫地平促进脑缺血再灌流猪EEG幅度的有效恢复且降低了EEG的异常率(P<0.01);参麦注射液有类似效果,但作用软弱(P<0.05);尼莫地平和参麦注射液均可抑制再灌流损伤后脑环磷酸腺苷(cAM)的升高(P<0.05);减轻脑水肿和大脑皮层损伤的程度。提示尼莫地平注射液和参麦注射液对缺血再灌流脑组织损伤有明显拮抗作用。

AIM: To observe the efficacy of prevention and treatment of nimodipine injection for delayed cerebrovascular spasma (DCVS) after subarachnoid hemorrhage (SAH). METHODS: Sixty patients with SAH were randomly divided into therapy group (M 20, F 10, age 54±s 6 a) and control group (M 21, F 9, age 55±5 a). All patients accepted therapy before 72 h after the onset of the attack. The patients of control group accepted conventional therapy (dehydration, hemostasis), therapy group accepted conventional therapy...

AIM: To observe the efficacy of prevention and treatment of nimodipine injection for delayed cerebrovascular spasma (DCVS) after subarachnoid hemorrhage (SAH). METHODS: Sixty patients with SAH were randomly divided into therapy group (M 20, F 10, age 54±s 6 a) and control group (M 21, F 9, age 55±5 a). All patients accepted therapy before 72 h after the onset of the attack. The patients of control group accepted conventional therapy (dehydration, hemostasis), therapy group accepted conventional therapy and nimodipine injection 10 mg in 50 mL, iv drip, qd×14 d. RESULTS: The morbidity of DCVS and mortality of SAH in the therapy group were obviously lower than that of control group (P<0.05); There was no statistically difference between the morbidity of rehemorrhage of the two groups (P>0.05). CONCLUSION: Nimodipine injection prevents DCVS following SAH. There is no danger of rehemorrhage.

目的:观察尼莫地平注射液防治蛛网膜下腔出血(SAH)后迟发性脑血管痉挛(DCVS)的疗效。方法:将60例SAH病人随机分为尼莫地平组(男性20例,女性10例,年龄54±s6a)和对照组(男性21例,女性9例,年龄55±5a)各30例。2组均于发病72h内接受治疗,对照组用脱水、止血等常规疗法,尼莫地平组在常规疗法基础上加用尼莫地平注射液50mL(含10mg),静脉滴注,qd×14d。结果:尼莫地平组DCVS发生率和SAH死亡率明显低于对照组(P<0.05);再出血发生率2组无明显差异(P>0.05)。结论:尼莫地平注射液预防SAH后DCVS疗效确切,且无增加再出血的危险。

 
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