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advance breast cancer
相关语句
  晚期乳腺癌
     PhaseⅡtrial of Exemestane in the treatment of postmenopausal women with advance breast cancer
     依西美坦治疗绝经后晚期乳腺癌Ⅱ期临床试验
短句来源
     Methods: 36 patients with advance breast cancer were intravenously infused with vinorelbine (25mg·m~(-2)) on day 1 and day 8, respectively, for 15 minutes and epirubicin (60mg·m~(-2)) on day 1 every 21~28 days for one cycle.
     方法:36晚期乳腺癌患者给予长春瑞宾25mg·m~(-2)静脉滴注15min,d1,d8; 表柔比星60mg·m~(-2),静脉冲入,d1。
短句来源
  相似匹配句对
     Advance of breast cancer resistance protein
     乳腺癌耐药蛋白的最新进展
短句来源
     Advance of the diagnosis and treatment of breast cancer
     乳癌诊治的进展
短句来源
     Advance in studies on c-erbB-2 of breast cancer
     乳腺癌c-erbB-2研究进展
短句来源
     Challenge to Radiotherapy from the Surgical Advance of Breast Cancer
     乳腺癌外科治疗的进展对放射治疗的挑战
短句来源
     Breast Cancer and Elastosis
     乳腺癌与弹力纤维增生
短句来源
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One hundred and fifteen cases of advanced breast cancer treatedwith the combination of vincristine, Thio-TEPA, 5-Fluorouracil, Durabolin and Prednisone were reported in this paper. The complete response rate was 13.0%, the partial response rate 48.7%, the no change rate 35.7%, and the progressive disease rate 2.6%. The median survival time was 14 months in the group of chemotherapy alone (76 cases); the 5-year survival rate was 38.1% in the group of multimodality therapy i.e. chemotherapy plus radical...

One hundred and fifteen cases of advanced breast cancer treatedwith the combination of vincristine, Thio-TEPA, 5-Fluorouracil, Durabolin and Prednisone were reported in this paper. The complete response rate was 13.0%, the partial response rate 48.7%, the no change rate 35.7%, and the progressive disease rate 2.6%. The median survival time was 14 months in the group of chemotherapy alone (76 cases); the 5-year survival rate was 38.1% in the group of multimodality therapy i.e. chemotherapy plus radical mastectomy plus radiotherapy (39 cases). Except one case died of myelosuppres-sion, the side effects, generally, were not serious, morderate leukopenia, oral ulceration, anorexia, nausea, vomiting, dizziness, and alopecia were found in a few patients. Only very few patients showed fever, abdominal pain or diarrhea, which all dissapeared immediately after the discontinuation of the drugs. This protocol did not take a long time, was quite convenient in using and also could be carried out in the outpatient department.

本文总结了应用长春新硷、噻替派或环磷酰胺、氟尿嘧啶、苯丙酸诺龙及强的松治疗晚期乳腺癌115例,取得完全缓解(CR)13.0%、部分缓解(PR)48.7%、无明显改变(NC)35.7%及恶化(PD)2.6%的疗效。其中单一化疗组(76例)的中数生存期为14个月;综合治疗(即化疗+根治术+放疗+化疗)组(39例)的5年生存率为38.1%。除1例死亡外,一般副作用不严重,计有白细胞轻度下降(占6.1%)及少数病人出现口腔溃疡、恶心、呕吐、食欲下降及脱发等,个别病例尚有发热、腹痛、腹泻等症状,均于停药后消失。化疗耗时不长,使用方便,可在门诊执行。

50 cases of spontaneous or artificial menopausal women, suffered from advanced breast-cancer at stage IV according to UICC system, were treated with tamoxifen from two different sources. Populations of cancer cells, from specimen of each case, should be carefully studied and divided either into hormonal receptor positive(HR + ) or negative (HR- ) according to Lee's fluorescence histochemical method. All of them received tamoxifen 10mg bid for at least three months. By this way most of...

50 cases of spontaneous or artificial menopausal women, suffered from advanced breast-cancer at stage IV according to UICC system, were treated with tamoxifen from two different sources. Populations of cancer cells, from specimen of each case, should be carefully studied and divided either into hormonal receptor positive(HR + ) or negative (HR- ) according to Lee's fluorescence histochemical method. All of them received tamoxifen 10mg bid for at least three months. By this way most of them could well tolerated

50例晚期乳腺癌妇女,比较国产和英制的他莫昔芬(tamoxifen)的疗效,剂量为10mg bid口服,疗程均在3mo(月)以上,随访6mo以上。结果表明激素受体检测可指导内分泌治疗取得较高效应,2种药物无显著差异。该药对乳腺癌疗效较高,毒副作用较低,安全性大,口服使用方便,优于其他内分泌治疗方案,可为绝经后晚期老年乳腺癌妇女首选的激素治疗药物。

After mastectomy of advanced breast cancer in 28 women(aged 49 ±SD 12yr;25 after menopause), the cancer recurred in 11 and metastasized in 17 patients. Estrogen receptor determination was done on 7 patients and all showed positive results. Each patient was given orally aminoglutethimide 0.75-1 g and prednisone 5 mg daily for at least over one month(the longest 10 months). The medication was stopped in 3 patients due to severe skin rash. The total effective rate was 57% (80% for metastasis in soft...

After mastectomy of advanced breast cancer in 28 women(aged 49 ±SD 12yr;25 after menopause), the cancer recurred in 11 and metastasized in 17 patients. Estrogen receptor determination was done on 7 patients and all showed positive results. Each patient was given orally aminoglutethimide 0.75-1 g and prednisone 5 mg daily for at least over one month(the longest 10 months). The medication was stopped in 3 patients due to severe skin rash. The total effective rate was 57% (80% for metastasis in soft tissues and 43% for metastasis in bone). Two typical patients were presented.

晚期乳腺癌28人全为女性,年龄49±SD 12岁,25人已绝经。均作过手术,11人复发、17人转移、7人雌激素受体阳性,其余未测。氨格鲁米特(aminoglutethimide,下简称AG)每日服0.75-1.0g、泼尼松5mg。3人因全身性皮疹中止治疗,其余均能耐受,耐受率89%。总有效率57%,软组织有效率80%,骨转移有效率43%。

 
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