耐药蛋白 resistance protein(169) resistant protein(7) resistance-related protein(10)   resistance protein      Objective:To investigate the expression and significance of the multidrug resistance-related genes multidrug resistance gene1(MDR1)、multidrug resistance-related protein(MRP)、lung resistance protein(LRP)mRNA and their proteins P-glycoprotein(P-gp)、MRP、LRP in human non small cell lung cancer(NSCLC)tissues and paratumor tissues.      目的:研究探讨非小细胞肺癌(NSCLC)组织和癌旁组织中多药耐药基因1(multidrug resistance gene1,MDR1)、多药耐药相关蛋白(multidrug resistance-related proteins,MRP)、肺耐药蛋白(lung resistance protein,LRP)mRNA及其相应蛋白P-gp、MRP、LRP的表达情况及临床意义。 短句来源      Expression of lung resistance protein and its relationship with drug resistance in epithelial ovarian tumor.      卵巢上皮性肿瘤组织中肺耐药蛋白的表达及与化疗耐药的关系 短句来源      Expression of multidrug resistance protein P-gp170 in bladder cancer      膀胱移行细胞癌多药耐药蛋白P-gp170的表达及意义 短句来源      Objective To explore the roles of MDR1 ( multi-drug resistance protein 1) , MRP1 ( multi-drug resistance related protein 1) , LRP( lung resistance protein) and BCRP( breast cancer resistance protein) in the phenomenon of multi-drug resistance ( MOR) in hepatoma. Methods Through exposing HePG2 cell line to gradually increased concentration of adriamycin ( ADM) , HePG2 multidrug resistant subcell line (HePG2/ADM) was induced.      目的研究4种耐药蛋白:多药耐药蛋白(multi-drug resistance protein 1,MDR1),多药耐药相关蛋白1(multi-drug resistance related protein 1,MRP1),肺耐药蛋白(lung resistance protein, LRP),乳腺癌耐药蛋白(breast cancer resistance protein,BCRP)在肝癌多药耐药中的作用。 短句来源      AIM: To explore the expression of four kinds of drug resistance related protein: P-glycoprotein((P-gp)),glutathione-S-transferases-π(GST-π),lung resistance protein(LRP),multidrug resistance related protein(MRP) in osteosarcoma cell lines Saos2 and U2OS,and in osteosarcoma and soft tissue sarcoma tissues from 34 patients and their correlations with chemotherapy resistance.      目的:探讨4种耐药相关蛋白-P-糖蛋白(P-gp)、谷胱甘肽S-转移酶-π(GST-π)、肺耐药蛋白(LRP)和多药耐药相关蛋白(MRP)在骨肉瘤细胞株Saos2和U2OS以及34例骨软组织肉瘤的表达及与化疗耐药的关系。 短句来源 更多          resistant protein      Correlations between ~(99)Tc~m-MIBI uptake and membrane potential of mitochondrion or lung resistant protein of tumor tissues      ~(99)Tc~m-MIBI在癌组织中的摄取与跨膜电位或肺耐药蛋白相关性 短句来源      Objective: To observe the effect of matrine on P 170 expressed by multi-drug resistance gene, lung resistant protein(LRP), and boposomeras Ⅱ.      目的 :实验观察苦参碱口服给药对化疗诱导的多药耐药基因表达产物P170 、肺耐药蛋白LRP和拓扑异构酶Ⅱ的影响 ,探讨其干预多药耐药的分子生物学基础 ,以指导临床应用苦参碱干预化疗多药耐药的产生。 短句来源      Objective: To observe the effect of tetrandrine on the P170 production expressed by multi-drug resistance gene, lung resistant protein (LRP), and topoisomeras Ⅱ and elucidate the underlying molecular mechanism.      目的:观察粉防己碱口服给药对化疗诱导的多药耐药基因表达产物P170、肺耐药蛋白LRP和拓扑异构酶Ⅱ(TOPOⅡ)的影响。 短句来源      It was caused by complicated reasons , among which the expression of the membrane transport - associated drug resistant protein, P - glycoprotein (P - gp) is the most common and important one.      MDR产生原因复杂，膜转运相关耐药蛋白中P-糖蛋白(P-gp)的表达是最常见、最重要的原因。 短句来源      The levels of cellular multidr ug resistant protein 1 (MRP1), glutathione-S-transferase (GST), and topoisomeras e-Ⅱ (TOPO-Ⅱ) were detected by flow cytometry (FCM). The level of intracellular glutathione (GSH) was measured by fluorescence-Coomassie light blue method.      用流式细胞仪(FCM)测定细胞多药耐药蛋白1(multidrugresistantprotein1,MRP1)、谷胱甘肽鄄S鄄转移酶(GST)及TOPO鄄Ⅱ蛋白表达量,荧光鄄考马斯亮蓝法检测细胞内GSH含量,原子吸收法测定细胞内铂浓度。 短句来源 更多          resistance-related protein      Objective:To investigate the expression and significance of the multidrug resistance-related genes multidrug resistance gene1(MDR1)、multidrug resistance-related protein(MRP)、lung resistance protein(LRP)mRNA and their proteins P-glycoprotein(P-gp)、MRP、LRP in human non small cell lung cancer(NSCLC)tissues and paratumor tissues.      目的:研究探讨非小细胞肺癌(NSCLC)组织和癌旁组织中多药耐药基因1(multidrug resistance gene1,MDR1)、多药耐药相关蛋白(multidrug resistance-related proteins,MRP)、肺耐药蛋白(lung resistance protein,LRP)mRNA及其相应蛋白P-gp、MRP、LRP的表达情况及临床意义。 短句来源      Objective:To investigate the expression of P-glycoprotein(P-gp),multidrug resistance-related protein(MRP),lung resistance-related protein(LRP),P53 and c-erbB-2 in untreated non-small cell lung cancer(NSCLC) and their relationship with each other.      目的:探讨P糖蛋白(P-gp)、多药耐药相关蛋白(MRP)、肺耐药蛋白(LRP)、P53蛋白及c-erbB-2蛋白在术前未经治疗的非小细胞肺癌(NSCLC)中的表达及相互间的关系。 短句来源      Objective To investigate the expression of the inutidrug resistance-related genes: mutidrug resistance gene1 (mdr1), mulidrug resistance-related protein (MRP)、 lung resistance protein (LRP) mRNA and its proteins: P-glycoprotein(P-gp), MRP、LRP in human non small cell lung cancer tissues and paratumor tissues ,Meanwhile determine whether these genes and proteins expression had relationship with clinical stage、 pathological type、 pathological classification and lymph node metastases ;      目的 检测非小细胞肺癌组织和癌旁组织中多药耐药基因(mutidrug resistance genel，mdrl)、多药耐药相关蛋白(mutidrug resistance-related proteins，MRP)、肺耐药蛋白(lung resistance protein，LRP)mRNA及其相应蛋白P-gp、MRP、LRP的表达情况及临床意义； 短句来源      Objective:To investigate the expression of multidrug resistance gene production P-Glycoprotein (PGP),multidrug resistance-associated protein (MRP1), lung resistance-related protein (LRP), and breast cancer resistance protein (BCRP) in primary breast carcinoma, and to determine whether such the expression can predict survival. Methods:Expression of the four proteins in 50 breast cancer patients was determined by immunohiostochemistry on formalin-fixed, paraffin-embedded tumor section.      目的:研究包括P-糖蛋白(P-glycoprotein,PGP)、多药耐药相关蛋白-1(Multidrug resistance-associated protein1,MRP1)、肺耐药相关蛋白(Lung resistance-related protein,LRP)和乳腺癌耐药蛋白(Breast cancer resistance protein,BCRP)在乳腺癌组织中的表达,并评估其在乳腺癌预后中的作用。 短句来源      The aim of this study is to investigate the expression of resistance-related proteins, P-glycoprotein (P-gp), multidrug resistance-associated protein (MRP), lung resistance-related protein (LRP), topoisomerase Ⅱ (Topo Ⅱ) and glutathion-S-transferase-π (GST-π) in non-small cell lung cancer (NSCLC) tissues and their clinical significance.      本研究的目的是探讨P糖蛋白(Pgp)、多药耐药相关蛋白(MRP)、肺耐药蛋白(LRP)、拓扑异构酶Ⅱ(TopoⅡ)、谷胱甘肽S转移酶π(GSTπ)在肺癌中的表达及其临床意义。 短句来源 更多          “耐药蛋白”译为未确定词的双语例句      There was no difference between HePG2 and L02 cells for mRNA expressions of the four genes (FMDR1 = 1006, FBCRP= 87. 49, FMRP1= 3. 43, FLRP= 2. 44, Pall >0. 05).      (3)L02和HePG2中4种耐药蛋白mRNA的表达均无差异(FMDR1=1006, FBCRP=87．49,FMRP1=3．43,FLRP=2．44,Pall>0．05)。 短句来源      The co-expression rate of P-gp and GST-π protein was 29.41%, of P-gp and TS protein was 29.41%, of GST-π and TS protein was 19.61%, of P-gp, GST-π and TS protein was 13.73% in cervical cancer.      宫颈癌中P-gp和GST-π蛋白共表达率为29.41%,GST-π和TS蛋白共表达率为29.41%,P-gp和TS蛋白共表达率为19.61%,3种耐药蛋白共表达率为13.73%。 短句来源      The co-expression rate of P-gp and Topo-Ⅱproteins was 20.7%（11/53）, of P-gp and GST-π proteins was 26.4%（14/53）,of GST-pi and Topo-Ⅱproteins was 32.1%(17/53) , of P-gp、GST-π and Topo-Ⅱproteins was 15.1%（8/53）.      Topo-Ⅱ和P-gp蛋白共表达率为20.7%（11/53），GST-π和P-gp蛋白共表达率为26.4%（14/53），GST-π和Topo-Ⅱ蛋白共表达率为32.1%（17/53），三种耐药蛋白共表达率为15.1%（8/53）。 短句来源      Results The positive ratios of the drug resistance factor were caculated as follows:7.7%,2.8%,5.8%,7.4%,for P-gp,MRP,LRP,GST-π,respectively.      结果各耐药蛋白单表达的阳性率分别为P-gP:7.7%,MRP:2.8%,LRP:5.8%,GSTπ:7.4%。 短句来源      Results:(1)PGP expression was observed in 41 of 50(82.0%),MRP1 in 43 of 50(86.0%),LRP in 40 of 50(80.0%),and BCRP in 29 of 50(58.0%)tumors.      结果:(1)各种耐药蛋白在乳腺癌组织中均有不同程度的表达,PGP、MRP1、LRP和BCRP的表达率分别为82·0%(41/50)、86·0%(43/50)、80·0%(40/50)和58·0%(29/50); 短句来源 更多        查询“耐药蛋白”译词为用户自定义的双语例句     我想查看译文中含有：的双语例句 为了更好的帮助您理解掌握查询词或其译词在地道英语中的实际用法，我们为您准备了出自英文原文的大量英语例句，供您参考。   resistance protein The goal of this study was to investigate the role of a multidrug resistance protein, P-glycoprotein (Pgp), in the evolution of CML treated with imatinib. 例句来源       MDR1, multidrug resistance-associated protein (MRP) and lung-resistance protein (LRP) have been identified as important adverse prognostic factors. 例句来源       The myxovirus resistance protein A (MxA) assay is recommended as the standard assay for the quantification of NAbs providing availability of reagents. 例句来源       Expressions of multidrug resistance 1 (MDR1), multidrug resistance-associated protein (MRP) and lung resistance protein (LRP) were detected by reverse transcription polymerase chain reaction (RT-PCR). 例句来源       Relationship between methylation status of multi-drug resistance protein(MRP) and multi-drug resistance in lung cancer cell line 例句来源       更多             resistant protein Boxin is a stable, heat and proteolysis resistant protein of 18?kDa. 例句来源       Both multi-drug resistant protein1 (MRP1) and P-glycoprotein were overexpressed in K562/ADR cells when compared with K562 parent cells (K562/P). 例句来源       PrP 27-30, a unique protease-resistant protein associated with scrapie infectivity, derives from the proteolytic cleavage of a larger precursor encoded by a host gene. 例句来源       Plaque amyloid was exclusively of the β/A4 type, but abundant abnormal protease-resistant protein was identified by Western blot analysis of brain extracts. 例句来源       We studied the immunocytochemical distribution of the prion or proteinase-resistant protein (PrP) during the evolution of experimental Creutzfeldt-Jakob disease (CJD) in mice. 例句来源       更多             resistance-related protein Expression of lung resistance-related protein, LRP, and multidrug resistance-related protein, MRP1, in normal human lung cells i 例句来源       The multidrug resistance-related protein MRP1 and the lung resistance-related protein LRP are associated with drug resistance against chemotherapeutics; they protect cells against toxic compounds. 例句来源       Therefore, the purpose of this study was to retrospectively evaluate the relationship between 99mTc-MIBI parathyroid imaging results and Pgp or multidrug resistance-related protein (MRP) expression in parathyroid adenomas. 例句来源       Polarized excretion of most isoflavone conjugates was inhibited by the multidrug resistance-related protein (MRP) inhibitor leukotriene C4 (0.1?μM) and the organic anion transporter (OAT) inhibitor estrone sulfate (10?μM). 例句来源       Two recently discovered proteins, lung resistance protein (LRP) and the multidrug resistance-related protein (MRP) have been implicated in the development of MDR. 例句来源       更多           没有找到相关文摘     相关查询: 耐药 药耐药 细胞耐药 耐药肿瘤 药耐药基因 大肠杆菌耐药 乳腺癌耐药 逆转耐药 高度耐药 结核病耐药 耐药肺结核 耐药结核病  对查询结果不满意

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